Abstract: Described herein are HSD17B13 inhibitors and pharmaceutical compositions comprising said inhibitors. The subject compounds and compositions are useful for the treatment of liver disease, metabolic disease, or cardiovascular disease, such as NAFLD or NASH, or drug induced liver injury (DILI).

Abstract: Disambiguating question answering responses by receiving voice command data associated with a first user, determining a first user identity according to the first user voice command data, determining a first user activity context according to the first user voice command data, determining a first response for the first user, receiving voice command data associated with a second user, determining a second user identity according to the second user voice command data, determining a second user activity context according to the second user voice command data, determining a second response for the second user, determining a predicted ambiguity between the first response and the second response, altering the first response according to the predicted ambiguity, and providing the first response and the second response.

Abstract: In one embodiment, a method includes acquiring an Internet Protocol version 6 (IPv6) address for a physical interface of a first network element. The method also includes configuring an Internet Protocol version 4 (IPv4) over IPv6 tunnel between the first network element and a second network element using the physical interface of the first network element. The method also includes acquiring an updated IPv6 address for the physical interface of the first network element and using an IPv6 Service Level Agreement (SLA) Hypertext Transfer Protocol (HTTP) operation to notify the second network element of the updated IPv6 address to establish a bidirectional IPv4 over IPv6 tunnel. The method further includes establishing a control connection with an IPv4 SD-WAN controller and automatically building an SD-WAN overlay tunnel with the bidirectional IPv4 over IPv6 tunnel as a transport.

Abstract: An aspect of the present disclosure facilitates resolving tickets in a multi-tenant environment. In one embodiment, a server receives a ticket for a tenant from a ticketing system and then determines a gross job representing a class of jobs suitable for resolution of the received ticket. The server then identifies a set of values for a set of system parameters characterizing the computing resources serving the tenant. The server selects a target job based on the combination of the determined gross job and the set of values for the set of system parameters. The selected target job is then executed to cause resolution of the ticket for the tenant. According to another aspect, the server performs the above noted actions automatically without manual intervention, in response to adding of the ticket into the ticketing system.

Abstract: Described herein are HSD17B13 inhibitors and pharmaceutical compositions comprising said inhibitors. The subject compounds and compositions are useful for the treatment of liver disease, metabolic disease, or cardiovascular disease, such as NAFLD or NASH, or drug induced liver injury (DILI).

Abstract: Described herein are HSD17B13 inhibitors and pharmaceutical compositions comprising said inhibitors. The subject compounds and compositions are useful for the treatment of liver disease, metabolic disease, or cardiovascular disease, such as NAFLD or NASH, or drug induced liver injury (DILI).

Abstract: Described herein are HSD17B13 inhibitors and pharmaceutical compositions comprising said inhibitors. The subject compounds and compositions are useful for the treatment of liver disease, metabolic disease, or cardiovascular disease, such as NAFLD or NASH, or drug induced liver injury (DILI).

Abstract: Provided herein are novel lipase inhibitors and methods for using the same to treat inflammation, multisystem organ failure, necrotic pancreatic acinar cell death, acute pancreatitis, sepsis (e.g., culture negative sepsis), burns, and acne. For example, provided herein are two novel lipase inhibitors useful in the methods described herein: or a pharmaceutically acceptable salt thereof.

Abstract: Disclosed herein a system, method, and computer program product for providing proactive guidance to users in order to execute a shift left model in software delivery. As disclosed, a processor may receive an issue resolution request. The processor may further access an issue resolution request repository where the issue resolution request repository may include details related to prior issue resolution requests. The processor may subsequently classify the issue resolution request based on the details related to the prior issue resolution requests. Accordingly, the processor may identify a root cause for the issue resolution request.

Abstract: In one set of embodiments, during an initial pre-copying phase, copies of the virtual disks of a VM or VM template can be distributed across one or more datastores, prior to the start of any cloning. This effectively seeds each datastore with a disk pool comprising a certain number of copies of the VM/VM template's virtual disks. Then, at the time of receiving a user request to create k clones from the VM/VM template, up to k copies of the VM/VM template's virtual disks that already reside in the disk pools of one or more target datastores can be moved from those disk pools to the clones' home folders on the target datastores, thereby reducing or eliminating the need to create brand new copies of the virtual disks on demand.

Abstract: Described herein is a method, system, and non-transitory computer readable medium for helping customers in accessing data through an application from a replica database, detecting whether the replica database, zone of availability of the replica database, or geographical region encompassing the zone of availability is experiencing an outage or other failure, and re-routing traffic to a backup replica database accordingly. To assess the status of the database, metrics are pushed in a secure manner from a private subnet to a public-facing monitoring agent, achieving a clear segregation of private subnet and public facing components. Further, circuit-breaker logic is included for preventing failure during updating DNS addresses during the re-routing process.

Abstract: Methods and systems are provided for controlling movement of a mobile medical device drive platform. In one example, a mobile platform includes a chassis configured to house one or more medical devices, an omnidirectional wheel system including an omnidirectional wheel coupled to the chassis, a battery housed in the chassis, the battery configured to supply power to drive the omnidirectional wheel system and/or supply power to operate the one or more medical devices, and a battery charging system housed in the chassis, where the battery charging system is configured to facilitate wired and/or wireless charging of the battery.

Abstract: In one embodiment, a method includes determining, by a router, a common prefix pool from a transport interface associated with a transport virtual private network (VPN). The method also includes identifying, by the router, a prefix associated with a service VPN and generating, by the router, an IPv6-to-IPv6 Network Address Translation (NAT66) prefix translation using the common prefix pool and the prefix. The NAT66 prefix translation includes a predetermined prefix length. The method further includes automatically installing, by the router, the NAT66 prefix translation into a translation table.

Abstract: Keepalive packets are transmitted between a sender node and a receiver node at an interval that varies depending on the transit times of previously transmitted keepalive packets. The transit time is based on when a keepalive packet is transmitted to the receiver node and when a corresponding feedback packet is received from the receiver node. The transmission interval varies depending on the path conditions between the sender node and the receiver node, which may be reflected in the transit time.

Abstract: Aspects of the present disclosure relate to methods, systems, and apparatus for conducting a radical treatment operation on a substrate prior to conducting an annealing operation on the substrate. In one implementation, a method of processing semiconductor substrates includes pre-heating a substrate, and exposing the substrate to species radicals. The exposing of the substrate to the species radicals includes a treatment temperature that is less than 300 degrees Celsius, a treatment pressure that is less than 1.0 Torr, and a treatment time that is within a range of 8.0 minutes to 12.0 minutes. The method includes annealing the substrate after the exposing of the substrate to the species radicals. The annealing includes exposing the substrate to molecules, an anneal temperature that is 300 degrees Celsius or greater, an anneal pressure that is within a range of 500 Torr to 550 Torr, and an anneal time that is less than 4.0 minutes.

Abstract: Provided herein are novel lipase inhibitors and methods for using the same to treat inflammation, multisystem organ failure, necrotic pancreatic acinar cell death, acute pancreatitis, sepsis (e.g., culture negative sepsis), burns, and acne. For example, provided herein are two novel lipase inhibitors useful in the methods described herein: or a pharmaceutically acceptable salt thereof.

Abstract: A method, computer system, and a computer program product for allocating unused computing resources of a plurality autonomous vehicles is provided. The present invention may include receiving at least one computation request from at least one user. The present invention may include identifying the unused computing resources of the plurality of autonomous vehicles. The present invention may include predicting an amount of computational activities performable by the unused computing resources of the plurality of autonomous vehicles. The present invention may include allocating the unused computing resources of the plurality of autonomous vehicles to perform the predicted amount of computational activities, wherein the received at least one computation request is allocated at least a portion of the unused computing resources. The present invention may include distributing a processing load to at least one of the plurality of autonomous vehicles.

Abstract: A computer system provides patient monitoring and treatment using electronic textiles. Biometric data pertaining to a user is received that is obtained over time from an electronic textile device associated with a body of the user. The biometric data is analyzed to identify positions and movements of the body. The identified positions and movements are analyzed to generate a knowledge corpus for the user that maps one or more of: positions, movements, and portions of the body to a health condition of the user. A treatment plan is generated, based on the knowledge corpus, that indicates a relatedness between the health condition of the user and the one or more positions, movements, and portions of the body. Embodiments of the present invention further include a method and program product for providing patient monitoring and treatment in substantially the same manner described above.

Abstract: The present application provides new processes for preparing arachidonoylethanolamine analogues. Intermediates useful for preparing the compounds are also provided.

Abstract: Disambiguating question answering responses by receiving voice command data associated with a first user, determining a first user identity according to the first user voice command data, determining a first user activity context according to the first user voice command data, determining a first response for the first user, receiving voice command data associated with a second user, determining a second user identity according to the second user voice command data, determining a second user activity context according to the second user voice command data, determining a second response for the second user, determining a predicted ambiguity between the first response and the second response, altering the first response according to the predicted ambiguity, and providing the first response and the second response.