Abstract: The invention is directed to opioid agonist peptides and their use.

Abstract: A hanger for securing an HVAC fluid line to a vehicle includes a rigid wire having a first end and a second end. The first end is formed to define a first aperture configured to receive a first fastener to couple the first end to the vehicle. The second end is configured to support the HVAC fluid line in a desired orientation.

Abstract: A hanger for securing an HVAC fluid line to a vehicle includes a rigid wire having a first end and a second end. The first end is formed to define a first aperture configured to receive a first fastener to couple the first end to the vehicle. The second end is configured to support the HVAC fluid line in a desired orientation.

Abstract: The invention is directed to opioid agonist peptides and their use.

Abstract: The invention is directed to opioid agonist peptides and their use.

Abstract: The present disclosure relates to a Dual Fin SCR device having two parallel fins on which cathode, anode, n- and p- type triggering taps are selectively doped, wherein one Fin (or group of parallel Fins) comprises anode and n-tap, and other Fin (or group of parallel Fins) comprises cathode and p-tap. As key regions of the proposed SCR (anode and cathode), which carry majority of current after triggering, are placed diagonally, they provide substantial benefit in terms of spreading current and dissipating heat. The proposed SCR ESD protection device helps obtain regenerative feedback between base—collector junctions of two back-to-back bipolar transistors, which enables the proposed SCR to shunt ESD current. The proposed SCR design enables lower trigger and holding voltage for efficient and robust ESD protection. The proposed SCR device/design helps offer a tunable trigger voltage and a holding voltage with highfailure threshold.

Abstract: The invention relates to novel Muramyl Dipeptide (MDP) derivative compound of structural Formula-VIII, a process for synthesis, intermediates used in the synthesis and use thereof. Wherein, R can be both linear and branched alkyl, aryl, substituted aryl and alkoxy alkyl. These compounds possess excellent pharmacological properties, in particular immunomodulating properties for use as adjuvant in vaccine formulations. These compounds are, particularly useful as adjuvants in vaccines.

Abstract: The invention relates to novel Muramyl Dipeptide (MDP) derivative compound of structural Formula-VIII, a process for synthesis, intermediates used in the synthesis and use thereof; wherein R1 and R2 both are hydrogen; or R1 is hydrogen and R2 is alkyl or aryl; or R1 is alkyl or aryl and R2 is hydrogen; or R1 and R2 both are alkyl or aryl (same or different groups); wherein alkyl group constitute C1-C6 alkyl or higher (both linear and branched) with or without heteroatoms; and aryl group constitute phenyl, substituted phenyl, heteraryl, arylalkyl and polynuclear aromatics. These compounds possess excellent pharmacological properties, in particular immunomodulating properties for use as adjuvant in vaccine formulations. These compounds are, particularly useful as adjuvants in vaccines.

Abstract: Example implementations relate to communication in a federated computing environment. For example, a method includes identifying, by a computing resource, at least one other computing resource within the federated computing environment, where the federated computing environment includes a pool of computing resources. The method also includes exchanging trust parameters with each of the at least one other computing resource, where the trust parameters are indicative of identification and authenticity of computing resources within the pool of computing resources. The method also includes communicating a first set of tokens to each of the at least one other computing resource, and receiving a second set of tokens from the at least one other computing resource, such that the first set of tokens and the second set of tokens form a global set of tokens for accessing the pool of computing resources of the federated computing environment.

Abstract: An X-ray system includes a multiple degree of freedom robotic arm mounted to a surface of a radiology suite, the robotic arm having one or more telescoping arm members, an X-ray source mounted on an end effector of the multiple degree of freedom robotic arm, at least one X-ray detector, and a work station coupled to the robotic arm, X-ray source, and X-ray detector, wherein the work station is configured to compute robotic arm trajectories for at least one scanning procedure and to control the robotic arm, X-ray source, and X-ray detector to effect the at least one scanning procedure.

Abstract: Aspects of the present disclosure provide a method for wireless communications that may be performed (e.g., by a user equipment) for location information reporting. The method generally includes determining one or more properties of the UE and adjusting one or more parameters of location information reporting based on the determined one or more properties.

Abstract: The present invention provides methods of making ?4?7 peptide monmer and dimer antagonists. Methods of the present invention include solid phase and solution phase methods, as well as synthesis via condensation of smaller peptide fragments. Methods of the present invention further include methods directed to the synthesis of peptides comprising one or more penicillamine residues.

Abstract: The present invention provides a compound of formula A: or a pharmaceutically acceptable salt thereof, wherein B, Q, R1, R5, R6, R7, R8 and Z are defined herein, which is a 2?-branched nucleoside useful for the treatment or prevention of viral infections, particularly dengue virus, yellow fever virus, West Nile virus, Japanese encephalitis virus, tick-borne encephalitis virus, Kunjin virus, Murray Valley encephalitis, St Louis encephalitis, Omsk hemorrhagic fever virus, bovine viral diarrhea virus, Zika virus and Hepatitis C virus.

Abstract: The present invention provides compounds useful as inhibitors of Ca2+/calmodulin-dependent protein kinase (CaMKII), compositions thereof, and methods of using the same.

Abstract: In an embodiment, a first media presentation session is established between a first Source and the Sink, and a second media presentation session between a second Source and the Sink. First and second media streams are streamed to the Sink by the first and second Sources, respectively. The Sink presents the first and second media streams in respective portions of a display screen, and detects user input at the Sink that is indicative of a trigger to transfer data originated from the first Source to the second Source. The Sink coordinates with one or both of the first Source and the second Source to facilitate the data to be delivered to the second Source in response to the detection. As a result of the coordination, the second Source receives the first Source-originated data (e.g., from the first Source directly, or via the Sink).

Abstract: Extended release pharmaceutical compositions comprising mycophenolate sodium as the active agent, wherein the said composition exhibits a characteristic release profile when subjected to in-vitro dissolution study, and wherein said mycophenolate sodium is released in a sustained manner in-vivo for a prolonged duration in such quantities that substantially alleviates or at least reduces the chances of causing any associated gastrointestinal side effect(s) without compromising the bioavailability of the said active agent are provided. The present invention also provides process of preparing dosage form compositions and prophylactic and/or therapeutic methods of using such dosage form. The compositions of the present invention are useful for the management such as prophylaxis, amelioration and/or treatment of immunosuppressant indicated disease(s)/disorder(s) especially for the treatment or prevention of organ, tissue or cellular allograft or xenograft rejection, e.g.

Abstract: The present invention provides a compound of formula A: or a pharmaceutically acceptable salt thereof, wherein B, Q, R1, R5, R6, R7, R8 and Z are defined herein, which is a 2?-branched nucleoside useful for the treatment or prevention of viral infections, particularly dengue virus, yellow fever virus, West Nile virus, Japanese encephalitis virus, tick-borne encephalitis virus, Kunjin virus, Murray Valley encephalitis, St Louis encephalitis, Omsk hemorrhagic fever virus, bovine viral diarrhea virus, Zika virus and Hepatitis C virus.

Abstract: An improved process for preparation of Olanzapine pamoate monohydrate from Olanzpaine is disclosed which comprises mixing at room temperature a solution of olanzapine prepared in water in presence of an acid, with a solution of pamoic acid prepared in water in presence of a base; stirring and maintaining the reaction mixture for a sufficient time till precipitation of solid and drying the solid to obtain olazapine pamoate monohydrate.

Abstract: Exemplary methods, apparatuses, and systems parse a form from a webpage to identify a plurality of input areas and corresponding input types. A multi-sequence form including a plurality of stages is generated. Each stage of the multi-sequence form is to be displayed and submitted independently of other stages of the multi-sequence form. Each stage of the multi-sequence form corresponds to a subset of the parsed form including one or more of the identified input areas. One of the plurality of identified input areas is identified to be of an input type categorized as having a higher likelihood of being completed and submitted by a user. The multi-sequence form is ordered such that the identified input area is ordered first. An updated version of the webpage is generated including the generated multi-sequence form in the determined order in place of the parsed form.

Abstract: The present invention provides a compound of formula A: or a pharmaceutically acceptable salt thereof, wherein B, Q, R1, R5, R6, R7, R8 and Z are as defined herein, which is a 2?-branched nucleoside useful for the treatment or prevention of viral infections, particularly dengue fever, yellow fever, West Nile virus, Japanese encephalitis virus, tick-borne encephalitis virus, Kunjin virus, Murray Valley encephalitis, St Louis encephalitis, Omsk hemorrhagic fever virus, bovine viral diarrhea virus, Zika virus and Hepatitis C virus.