Abstract: The invention relates to novel Muramyl Dipeptide (MDP) derivative compound of structural Formula-VIII, a process for synthesis, intermediates used in the synthesis and use thereof. Wherein, R can be both linear and branched alkyl, aryl, substituted aryl and alkoxy alkyl. These compounds possess excellent pharmacological properties, in particular immunomodulating properties for use as adjuvant in vaccine formulations. These compounds are, particularly useful as adjuvants in vaccines.

Abstract: A first information handling system may determine a first bandwidth of a first connection between the first information handling system and a client information handling system. The first information handling system may also determine a second bandwidth of a second connection between a second information handling system and the client information handling system. The first information handling system may determine that the first bandwidth is greater than the second bandwidth. Based on the determination, the first information handling system may be designated as a VRRP master node based. Based on the designation as the VRRP master node, the first information handling system may control VRRP operation of the first and second information handling systems.

Abstract: Presented herein are systems and methods that provide traffic recover when virtual router redundancy protocol (VRRP) virtual media access control (VMAC) failures occur in a link aggregation group fabric environment. In one or more embodiments, automatic traffic recovery may be accomplished using internode link control messages to synchronize a VRRP VMAC failure that has been encountered by one LAG node with a LAG peer node. If a database associated with the failed LAG node comprises no entry that indicates that the failure scenario has previously occurred in the LAG peer node, a forwarding path entry rule may be generated to route traffic via the internode link, thereby, reducing data loss through routing failures and the like.

Abstract: The present invention provides compounds useful as inhibitors of Ca2+/calmodulin-dependent protein kinase (CaMKII), compositions thereof, and methods of using the same.

Abstract: The present invention is directed towards a process for the preparation of Cariprazine (Ia) or a pharmaceutically acceptable salt thereof, wherein, N,N-dimethyl-1H-imidazole-1-carboxamide alkyl halide (VII) is reacted with trans-4-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)cyclohexanamine or a salt thereof (IIa) to produce Cariprazine (Ia) or a pharmaceutically acceptable salt thereof. The present invention is also directed towards amorphous form of Cariprazine hydrochloride (I) and solid dispersion of Cariprazine hydrochloride (I), and its preparation thereof.

Abstract: An aspect of the present disclosure facilitates resolving tickets in a multi-tenant environment. In one embodiment, a server receives a ticket for a tenant from a ticketing system and then determines a gross job representing a class of jobs suitable for resolution of the received ticket. The server then identifies a set of values for a set of system parameters characterizing the computing resources serving the tenant. The server selects a target job based on the combination of the determined gross job and the set of values for the set of system parameters. The selected target job is then executed to cause resolution of the ticket for the tenant. According to another aspect, the server performs the above noted actions automatically without manual intervention, in response to adding of the ticket into the ticketing system.

Abstract: A dumper body is disclosed. The dumper body may include a pivot assembly. The dumper body may include at least one of: a set of ribs, wherein the set of ribs is connected to the pivot assembly such that the set of ribs is comprised of multiple respective discontinuous structures, and a set of stringers, wherein the set of stringers includes a respective stringer cut-out around an outside surface of a bed plate of the dumper body at a point where a top plate of the dumper body connects to an inside surface of the bed plate.

Abstract: A first information handling system may determine a first bandwidth of a first connection between the first information handling system and a client information handling system. The first information handling system may also determine a second bandwidth of a second connection between a second information handling system and the client information handling system. The first information handling system may determine that the first bandwidth is greater than the second bandwidth. Based on the determination, the first information handling system may be designated as a VRRP master node based. Based on the designation as the VRRP master node, the first information handling system may control VRRP operation of the first and second information handling systems.

Abstract: Presented herein are systems and methods that provide traffic recover when virtual router redundancy protocol (VRRP) virtual media access control (VMAC) failures occur in a link aggregation group fabric environment. In one or more embodiments, automatic traffic recovery may be accomplished using internode link control messages to synchronize a VRPP VMAC failure that has been encountered by one LAG node with a LAG peer node. If a database associated with the failed LAG node comprises no entry that indicates that the failure scenario has previously occurred in the LAG peer node, a forwarding path entry rule may be generated to route traffic via the internode link, thereby, reducing data loss through routing failures and the like.

Abstract: The present invention provides compounds useful as inhibitors of Ca2+/calmodulin-dependent protein kinase (CaMKII), compositions thereof, and methods of using the same.

Abstract: An X-ray system includes a multiple degree of freedom robotic arm mounted to a surface of a radiology suite, the robotic arm having one or more telescoping arm members, an X-ray source mounted on an end effector of the multiple degree of freedom robotic arm, at least one X-ray detector, and a work station coupled to the robotic arm, X-ray source, and X-ray detector, wherein the work station is configured to compute robotic arm trajectories for at least one scanning procedure and to control the robotic arm, X-ray source, and X-ray detector to effect the at least one scanning procedure.

Abstract: The invention is directed to opioid agonist peptides and their use.

Abstract: A mobile X-ray system for digital tomography is disclosed. The mobile X-ray system comprising a multiple degree of freedom robotic arm comprising one or more extendable arms and a column member; an X-ray source mounted on an extendable arm of the one or more extendable arms; an X-ray detector; and a control unit coupled to the robotic arm, the X-ray source and the X-ray detector, wherein the control unit is configured to control the movement of the extendable arm and the column member for moving the X-ray source along a path to perform tomography imaging of a subject.

Abstract: The present disclosure relates to a Dual Fin SCR device having two parallel fins on which cathode, anode, n- and p-type triggering taps are selectively doped, wherein one Fin (or group of parallel Fins) comprises anode and n-tap, and other Fin (or group of parallel Fins) comprises cathode and p-tap. As key regions of the proposed SCR (anode and cathode), which carry majority of current after triggering, are placed diagonally, they provide substantial benefit in terms of spreading current and dissipating heat. The proposed SCR ESD protection device helps obtain regenerative feedback between base-collector junctions of two back-to-back bipolar transistors, which enables the proposed SCR to shunt ESD current. The proposed SCR design enables lower trigger and holding voltage for efficient and robust ESD protection. The proposed SCR device/design helps offer a tunable trigger voltage and a holding voltage with highfailure threshold.

Abstract: One example provides a method for authenticating a computing device received from a manufacturer, the method including establishing a secured connection with the computing device, receiving, from the computing device, a first set of security artifacts, and retrieving, from a secure cloud storage location, a second set of security artifacts, the second set of security artifacts including the EK public key and the PCR values for the computing device obtained during manufacturing. The method further comprises, when the first set of security artifacts matches the second set of security artifacts, then verifying the computing device as trusted and permitting communication between the computing device and a secured computing environment, and when the first set of security artifacts does not match the second set of security artifacts, then not verifying the computing device as trusted and not permitting communication between the computing device and the secured computing environment.

Abstract: The invention relates to novel Muramyl Dipeptide (MDP) derivative compound of structural Formula-VIII, a process for synthesis, intermediates used in the synthesis and use thereof; wherein R1 and R2 both are hydrogen; or R1 is hydrogen and R2 is alkyl or aryl; or R1 is alkyl or aryl and R2 is hydrogen; or R1 and R2 both are alkyl or aryl (same or different groups); wherein alkyl group constitute C1-C6 alkyl or higher (both linear and branched) with or without heteroatoms; and aryl group constitute phenyl, substituted phenyl, heteraryl, arylalkyl and polynuclear aromatics. These compounds possess excellent pharmacological properties, in particular immunomodulating properties for use as adjuvant in vaccine formulations. These compounds are, particularly useful as adjuvants in vaccines.

Abstract: In an embodiment, a first media presentation session is established between a first Source and the Sink, and a second media presentation session between a second Source and the Sink. First and second media streams are streamed to the Sink by the first and second Sources, respectively. The Sink presents the first and second media streams in respective portions of a display screen, and detects user input at the Sink that is indicative of a trigger to transfer data originated from the first Source to the second Source. The Sink coordinates with one or both of the first Source and the second Source to facilitate the data to be delivered to the second Source in response to the detection. As a result of the coordination, the second Source receives the first Source-originated data (e.g., from the first Source directly, or via the Sink).

Abstract: A dumper body is disclosed. The dumper body may include a pivot assembly. The dumper body may include at least one of: a set of ribs, wherein the set of ribs is connected to the pivot assembly such that the set of ribs is comprised of multiple respective discontinuous structures, and a set of stringers, wherein the set of stringers includes a respective stringer cut-out around an outside surface of a bed plate of the dumper body at a point where a top plate of the dumper body connects to an inside surface of the bed plate.

Abstract: The present invention provides methods of making ?4?7 peptide monomer and dimer antagonists. Methods of the present invention include solid phase and solution phase methods, as well as synthesis via condensation of smaller peptide fragments. Methods of the present invention further include methods directed to the synthesis of peptides comprising one or more penicillamine residues.