Abstract: A method of manufacturing an ultrasonic welding-based microfluidic device, the method including: forming a bottom board having two welding stoppers formed right and left and having a certain height and a certain interval; forming a top board having two energy directors formed with an interval greater than the interval between the two welding stoppers; putting the top board on the bottom board to locate the energy directors at the outside of welding stoppers, respectively; and welding the top board to the bottom board by using ultrasonic welding, wherein a channel is formed between the two welding stoppers without additional energy directors. Accordingly, it is possible to prevent a phenomenon that a fluid irregularly flows due to an uneven surface formed on a side of the channel while the energy directors are melted.

Abstract: Provided is a method and an apparatus for extracting an edge of a distal radius metaphysis. The method includes: setting a region of interest including a distal radius in an X-ray image; setting a potential energy distribution of the region of interest by using a gradient of gray levels; setting a temporary edge adjacent to both sides of a distal radius metaphysis and a side of an epiphysis in the region of interest; and extracting a detailed edge of the distal radius metaphysis having minimum energy by adjusting the set temporary edge using a metropolis annealing technique.

Abstract: The invention provides a method of correcting a distance between an ambient intelligence display and a user using a linear regression and a smoothing, by which distance information of a user who approaches to the display can be accurately output even in an unanticipated condition using a passive infrared (PIR) sensor and an ultrasonic device.

Abstract: An apparatus for supporting taking medicine includes a medicine storage unit which has a plurality of medicine storage holes to store therein medicines to be taken by a user, a sensor controller which determines whether the medicine storage holes include medicines therein, and a medicine taking service unit which receives a preset schedule by synchronizing with a personal computer, checks whether a user has taken medicine according to a determination of the sensor controller and informs a user to take a medicine according to the preset schedule. Thus, users who should take various medicines on a regular basis for daily life may observe the medicine taking time.

Abstract: An apparatus of managing quality of sleep includes a weight sensor unit including a plurality of pressure sensors, which detect pressures in response to a presence and a movement of a user; an environment sensor including multiple sensors, which detect an environment surrounding the user in a sleep; and a controller for collecting and analyzing information, detected by the weight sensor unit and the environment sensor unit, and classifying and managing the analyzed information according to quality of sleep. The apparatus provides an optimized sleep environment adequate for a subject by learning various sleep environments, and provides a comfortable and cozy sleep environment to the subject to restore energy and be refreshed, so that the subject can enjoy energetic and effective daytime life.

Abstract: Provided is a disposable multi-layered filtration device for the separation of blood plasma which can be applied to a biochip and appropriate for disposal uses. The filtration device for the separation of blood plasma includes: an upper substrate including a blood inlet; an intermediate substrate including a filtering unit for extracting blood plasma from blood flowing through the blood inlet; and a lower substrate including an air outlet, wherein the upper substrate, the intermediate substrate, and the lower substrate are stacked and adhered.

Abstract: Provided are a method and apparatus for clustering gene expression profiles by using the Gene Ontology (GO). The method includes: selecting one or more GO terms from a GO tree; receiving gene expression data sets; classifying the gene expression data sets into groups according to the GO terms; firstly clustering gene expression data belonging to each of the groups based on a similarity of the gene expression data; and secondly clustering the gene expression data sets by using the result of the first clustering as a seed.

Abstract: A method and apparatus provide geriatric care management service. The apparatus comprises a plurality of sensors, which generate sensor signals for informing daily behavior or health of an aged person, a signal processor, which analyzes the sensor signals to generate daily behavior information, an emergency situation manager, which informs a care giver that an emergency situation occurs and generates emergency situation occurrence information, an abnormal symptom manager, which analyzes the daily behavior information to informs the care giver whether or not the abnormal symptom occurs and generates abnormal symptom occurrence information, and a care information manager, which summarizes the daily behavior information, the emergency situation occurrence information, and the abnormal symptom occurrence information and generates care information.

Abstract: Apparatus and method for refining subject activity classification for the recognition of daily activities of a subject, and a system for recognizing daily activities using the same. The refining apparatus improves the correctness of subject activity classification using daily activities of a subject, activation time information of sensors mounted on objects associated with the daily activities of the subject, and the suitability of a continuous activity pattern in relation to the daily activities. This improves the correctness of subject activity classification that becomes basic information in daily activity analysis.

Abstract: There are provided a method and system for sensing abnormal signs in daily activities, the method comprising, at the system, sensing the daily activities, reading previously stored daily activity information, generating a daily activity sequence based thereon, sensing the abnormal signs from the daily activity sequence by using a preset sequence alignment algorithm, and providing the sensed abnormal signs to a user. As described above, the abnormal signs, which should be checked to provide care services, are sensed via changes in a daily activity pattern and added to a care service system that will be installed in welfare facilities for the aged or a home of a solitary old person, thereby effectively sensing the abnormal signs in daily activities of the aged.

Abstract: There is provided a daily activity recognition system using sensors installed in required positions in a home to recognize daily activities of an old person, the system including: a radio frequency (RF) management unit receiving data measured by a plurality of sensors installed in required positions in a home, recognizing a corresponding sensor transmitting the received data, and converting the received data into a basic activity corresponding to the recognized sensor; a buffer management unit storing the basic activity received from the wireless processing manager in an internal buffer; and a daily activity recognition unit recognizing daily activities of an old person at each point in time previously set, based on the basic activity stored in the buffer. The daily activities of the old person are recognized and stored in a database, thereby providing various services related to the health of the old person.

Abstract: Provided is a method for manufacturing a floating structure of a MEMS. The method for manufacturing a floating structure of a microelectromechanical system (MEMS), comprising the steps of: a) forming a sacrificial layer including a thin layer pattern doped with impurities on a substrate; b) forming a support layer on the sacrificial layer; c) forming a structure to be floated on the support layer by using a subsequent process; d) forming an etch hole exposing both side portions of the thin layer pattern; and e) removing the sacrificial layer through the etch hole to form an air gap between the support layer and the substrate.

Abstract: The present invention relates to an apparatus and method for recognizing biological named entity from biological literature based on united medical language system (UMLS). The apparatus and the method receives metathesaurus from the UMLS, constructs a concept name database, a single name database and a category keyterm database, which are language resources to be used recognize a named entity, receives each concept name stored in the concept name database, extracts features of each of the concept names by using data stored in the single name database and the category keyterm database, constructs a rule database by creating rules used to recognize the named entity and filtering the rules by using the extracted features, receives a biological literature, extracts nouns and noun phrases that are candidate named entities, applies the rules stored in the rule database to the nouns and the noun phrases, and recognizes the named entities.

Abstract: Provided are a micro gas sensor for measuring a gas concentration configured to achieve a high heating and cooling rate of a gas sensitive layer, achieve temperature uniformity, and achieve durability against thermal impact and mechanical impact; and a method for manufacturing the micro gas sensor. The micro gas sensor includes: a vacuum cavity disposed in a substrate; a support layer covering the vacuum cavity; a sealing layer sealing the support layer and the vacuum cavity; a micro heater disposed on the sealing layer; a plurality of electrodes disposed on the micro heater, insulated from the micro heater; and a gas sensitive layer covering the electrodes.

Abstract: Provided is an apparatus and method for comparing a protein structure, which can search a protein similar to an inquiry protein in a 3D protein database in real time by describing a feature of a protein structure by using a three-dimensional (3D) relative directional angle (RDA) and a Fourier descriptor. The apparatus includes: a 3D RDA coder configured to code a 3D RDA of a target protein data or an inquiry protein data inputted from the outside; a Fourier transformer configured to obtain Fourier coefficients by Fourier transforming 3D RDA coding values coded by the 3D RDA coder; a comparator configured to compare the obtained Fourier coefficient of the target protein data with the obtained Fourier coefficient of the inquiry protein data; and a data generator configured to output protein data in order from high similarity to low similarity according to the comparison result of the comparator.

Abstract: Provided is an apparatus and method for predicting gene modules controlled by the same set of transcription factors and performing the same function in a cell, using gene expression data and transcription factor binding information.

Abstract: Provided is a blood plasma separator for separating blood plasma and blood cells from whole blood without an additional complicated structure by passing the whole blood through a micro channel having a predetermined shape to make the whole blood flow turbulently and cause a velocity difference or deflection between flows of the blood plasma and the blood cells of the whole blood, and a blood plasma separation method thereof. The blood plasma separator includes: a body; a micro channel formed in the body to allow blood to pass therethrough; a separation member formed at the micro channel to make flow of blood cells or blood plasma turbulent to separate the blood cells from the blood plasma; an inlet connected to the micro channel and configured to introduce blood into the micro channel; and an outlet connected to the micro channel and configured to discharge blood from the micro channel.

Abstract: Provided is a layout method for protein-protein interaction networks based on a seed protein, which is for performing multiple stages of nesting centered on a node having a high degree of physical relationship, and performing multiple stages of extension and force directed placement (FDP) with respect to a final nest graph. The layout method includes the steps of: a) extracting a node list of each sub-graph constituting a protein-protein interaction network, and aligning the node list according to adjacency of nodes; b) selecting a seed protein from the aligned node list according to node priority and nest relationship with another node; c) nesting adjacent nodes centered on the selected seed protein to generate a nested node; and d) selecting an initial position of the generated nested node, placing the nodes of the nested nodes on respective division points, centered on the seed protein, and then performing layout.

Abstract: Provided is an apparatus and method for detecting a ligand through automatic specific site extraction and allow a convenient and speedy protein structure-based drug design by detecting sequences and structures of protein binding sites or detecting structures of protein binding sites, and then automatically extracting a specific site to detect a ligand. The ligand detecting apparatus includes: an input data processing unit for processing input data; a binding site extraction unit for extracting a binding site from the data; a user input unit for allowing a user to select a comparison type; a manual like-binding-site comparison unit for manually comparing a binding site of a target protein with a like binding site of a protein of a database to extract a specific site; an automatic like-binding-site comparison unit; and a ligand detection unit for performing virtual screening on the specific site.

Abstract: Provided is a micro filtration device for separating blood plasma from whole blood without external actuation, and a method for fabricating the micro filtration device. The micro filtration device for separating blood plasma from whole blood includes: a whole blood inlet through which whole blood is introduced; a blood plasma outlet through which blood plasma separated from whole blood is discharged; a micro channel for connecting the whole blood inlet and the blood plasma outlet; a micro pump formed under the whole blood inlet to generate an air pressure without external actuation for moving whole blood from the whole blood inlet toward the blood plasma outlet through the micro channel; and a microstructure formed in the micro channel for separating blood plasma from the whole blood.