Abstract: A method of preparing a fiber-reinforced polymer composite is provided. The method includes (a) providing a swollen clay material; (b) chemically modifying a surface of the swollen clay material with an organosilane to form a silane-modified clay material; (c) intercalating the silane-modified clay material with a binder to form an intercalated clay material; and (d) melt compounding the intercalated clay material with a mixture comprising a polymer and fiber to form the fiber-reinforced polymer composite. A fiber-reinforced polymer composite is also provided.

Abstract: In accordance with some embodiments, a downhole drilling tool comprises a bit body, a blade on an exterior portion of the bit body, and a gage pad on the blade. The gage pad includes a ball retainer and a ball located in the ball retainer such that an exposed portion of the ball is positioned to contact a wellbore and rotate in response to frictional engagement with the wellbore.

Abstract: The present invention relates to chemical constituents of the hydro-alcoholic extract of root of Lasia spinosa (L.) Thwait. More particularly, it relates to the bioactive chemical composition of Lasia spinosa (L.) Thwait and its anticancer effect. The present invention has application in the treatment of human esophageal carcinoma.

Abstract: Disclosed are improved cutters for fixed-cutter rotating drill bits. One cutter includes a substrate defining a slot therein and being configured to be coupled to a middle portion of a blade of the drill bit, and a cutting element secured within the slot and having at least a portion of the cutting element extending out of the slot, the cutting element further having a first face and a second face, wherein portions of the first and second faces are supported by the substrate within the slot.

Abstract: A method of designing a downhole drilling tool may include generating a three dimensional (3D) downhole drilling tool model and simulating engagement of the drilling tool model with a 3D model of a borehole bottom. First and second cutting zones of first and second cutting elements may be determined based on areas of the first and second cutting elements that engage the borehole bottom, where the first and second cutting zones respectively have first and second cutting zone shapes. First and second cutting forces for the first and second cutting elements may be calculated based on the respective first and second cutting zone shapes. A drilling efficiency of the drilling tool model may be modeled based at least on the first cutting force and the second cutting force and a design parameter of the drilling tool model may be modified based on the drilling efficiency of the drilling tool model.

Abstract: Various downhole drilling tools designed and manufactured at least in part on evaluating respective forces acting on respective groups and sets of cutting elements during simulated engagement with the downhole end of a wellbore and drilling from a first downhole formation into a second downhole formation. Simulating forces acting on each cutting element as the cutting element contacts a downhole formation may be used to force balance downhole drilling tools during transition drilling or non-uniform downhole drilling conditions. Multilevel force balanced downhole drilling tools may be designed using five respective simulations, cutter group level, neighbor cutter group level, cutter set level, group of N (N=3 or N=4) consecutive cutters level and all cutters level. Various cutter layout procedures and algorithms may also be used to design multilevel force balanced downhole drilling tools which may drill faster with higher lateral stability, especially during downhole transiting drilling conditions.

Abstract: According to some embodiments of the present disclosure, a method of determining a critical depth of cut of a drill bit comprises selecting a radial swath associated with an area of a bit face of a drill bit. The method further comprises identifying a plurality of cutting elements disposed on the bit face that each include at least a portion located within the radial swath. The method also comprises identifying a depth of cut controller (DOCC) disposed on the bit face and configured to control a depth of cut of the portions of the plurality of cutting elements located within the radial swath. The method additionally comprises calculating a critical depth of cut associated with the radial swath and DOCC based on a depth of cut associated with each portion of the plurality of cutting elements located within the radial swath and controlled by the DOCC.

Abstract: The present disclosure relates to a method of forming a metallic layer having pores extending therethrough, the method comprising the steps of: (a) contacting a cathode substrate with an electrolyte solution comprising at least one cation; reducing the cation to deposit the metallic layer on a surface of the cathode substrate; and (c) generating a plurality of non-conductive regions on the cathode substrate surface during reducing step (b); wherein the deposition of the metallic layer is substantially prevented on the non-conductive regions on the cathode substrate surface to thereby form pores extending through the deposited metallic layer. The present disclosure further provides a metallic porous membrane fabricated by the disclosed process.

Abstract: In accordance with some embodiments of the present disclosure, a method of designing a drill bit comprises determining placements on a drill bit for a plurality of cutting elements at a plurality of radial coordinates of the drill bit. The method further comprises determining a substrate-based critical depth of cut for a substrate of each cutting element and generating a substrate-based critical depth of cut control curve based on the substrate-based critical depth of cut at each radial coordinate. The method also comprises comparing the substrate-based critical depth of cut control curve and the threshold critical depth of cut control curve and adjusting a drill bit design parameter if the substrate-based critical depth of cut control curve is less than or equal to the threshold critical depth of cut control curve at a radial coordinate.

Abstract: A hybrid drill bit includes a bit body having a central bit body axis, a roller cone at an end of the bit body and rotatably coupled to the bit body about a roller cone axis, and a disc at the end of the bit body and rotatably coupled to the bit body about a disc axis. The roller cone axis extends toward the central bit body axis. The disc axis is transverse to a radial of the central bit body axis through a center of the disc, and the disc includes a plurality of disc cutters.

Abstract: A method of designing a drill bit is disclosed. The method includes determining a location of a bit coordinate system in a wellbore coordinate system and generating a bit profile based on an angular coordinate around a wellbore axis of a wellbore and the location of the bit coordinate system. The bit profile is based on a cutting edge of a first cutting element on an exterior portion of a first blade. The method also includes determining a cutting layer volume based on the bit profile and identifying a weak zone based on the cutting layer volume being less than a predefined minimum cutting layer volume. The method includes determining a location for a second cutting element on the exterior portion of a second blade based on the weak zone.

Abstract: Various downhole drilling tools designed and manufactured at least in part on evaluating respective forces acting on respective groups and sets of cutting elements during simulated engagement with the downhole end of a wellbore and drilling from a first downhole formation into a second downhole formation. Simulating forces acting on each cutting element as the cutting element contacts a downhole formation may be used to force balance downhole drilling tools during transition drilling or non-uniform downhole drilling conditions. Multilevel force balanced downhole drilling tools may be designed using five respective simulations, cutter group level, neighbor cutter group level, cutter set level, group of N (N=3 or N=4) consecutive cutters level and all cutters level. Various cutter layout procedures and algorithms may also be used to design multilevel force balanced downhole drilling tools which may drill faster with higher lateral stability, especially during downhole transiting drilling conditions.

Abstract: A hybrid drill bit includes a bit body having a central bit body axis at a center of the bit body, a blade on the bit body extending from an end of the bit body, and a roller disc rotatably coupled to the bit body about the end of the bit body to rotate on a roller disc axis. The roller disc axis extends toward the central bit body axis, and the blade includes a plurality of fixed cutting elements.

Abstract: Disclosed is a natural compound, Oblongifolin C, isolated from a natural plant comprising Garcinia species such as Garcinia yunnanesis Hu, for its effects of anti-migration and anti-invasion against cancer and its use as an anticancer drug. The treated cancers comprise cervical cancers and esophageal cancers. The cancer treatment comprises inhibition of cancer metastasis and inhibition of autophagic flux.

Abstract: In accordance with some embodiments of the present disclosure, a method of modeling a downhole drilling tool is disclosed. The method may include identifying a location for each of a plurality of cutlets associated with each of a plurality of cutting elements. The method may further include calculating a depth of cut for each cutlet based on the location of the cutlet and a three dimensional model of a borehole bottom. Additionally, the method may include generating a three dimensional model of a rock chip for each cutting element, in response to at least one depth of cut being greater than a critical depth of cut, each three dimensional model including a two dimensional model of a rock chip associated with each cutlet. The method may also include updating the three dimensional model of the borehole bottom by removing each three dimensional model of a rock chip.

Abstract: According to some embodiments of the present disclosure, a method of determining a critical depth of cut of a drill bit comprises selecting a radial swath associated with an area of a bit face of a drill bit. The method further comprises identifying a plurality of cutting elements disposed on the bit face that each include at least a portion located within the radial swath. The method also comprises identifying a depth of cut controller (DOCC) disposed on the bit face and configured to control a depth of cut of the portions of the plurality of cutting elements located within the radial swath. The method additionally comprises calculating a critical depth of cut associated with the radial swath and DOCC based on a depth of cut associated with each portion of the plurality of cutting elements located within the radial swath and controlled by the DOCC.

Abstract: A downhole drilling tool designed for drilling a wellbore is disclosed. The drilling tool includes a bit body and a first plurality of blades and a second plurality of blades on exterior portions of the bit body. A first group of track-set cutting elements is on exterior portions of the first plurality of blades and a second group of track-set cutting elements is on the second plurality of blades. The first and second plurality of blades and the first group and second group of track-set cutting elements cooperate with each other to form a composite bit face profile such that each respective group of at least three neighbor cutting elements on the composite bite face profile is force balanced with respect to each other.

Abstract: The present invention disclosed a compound, proanthocyanidin A1 (PA1), which is isolated from Lasia spinosa (L.) Thwait, for its effects in shortening of clolon length, reducing colonic tissue damage, suppressing colonic myeloperoxidase activity with colitis. The said compound can be used in treating inflammatory diseases and anti-cancer leading compound.

Abstract: A downhole drilling tool designed for drilling a wellbore is disclosed. The drilling tool includes a bit body, and a first plurality of blades and a second plurality of blades on exterior portions of the bit body. A first group of cutting elements is located on exterior portions of the first plurality of blades. A second group of cutting elements is located on the second plurality of blades and under-exposed with respect to the first group of cutting elements. The first and second plurality of blades and the first group and second groups of cutting elements cooperate with each other to form a composite bit face profile such that each respective group of at least three neighbor cutting elements on the composite bit face profile is force balanced with respect to each other.

Abstract: The present invention relates to chemical constituents of the hydro-alcoholic extract of root of Lasia spinosa (L.) Thwait. More particularly, it relates to the bioactive chemical composition of Lasia spinosa (L.) Thwait and its anticancer effect. The present invention has application in the treatment of human esophageal carcinoma.