Patents by Inventor Shinichi Yamaguchi
Shinichi Yamaguchi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20110192972Abstract: A first mass analysis is executed in a condition that gas is not introduced into a loop-flight chamber (4), and a time-of-flight spectrum obtained in a data processor (12) is stored in a storage unit (13). Next, a second mass analysis is executed on the same sample as the one used in the first mass analysis in a condition that a valve (8) is opened and helium gas (He) is introduced into the loop-flight chamber (4), and the time-of-flight spectrum is obtained in the data processor (12). If different kinds of ions having the same m/z value exit, these ions form a single peak in the first time-of-flight spectrum, while these ions appear as separate peaks in the second time-of-flight spectrum even though they have the same m/z value. This is because, in the second mass analysis, the ions collide with the gas and have different times of flight depending on their difference in size.Type: ApplicationFiled: September 16, 2008Publication date: August 11, 2011Applicant: SHIMADZU CORPORATIONInventors: Osamu Furuhashi, Shinichi Yamaguchi, Hideaki Izumi
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Publication number: 20110192971Abstract: A variety of ions generated in an ion source are made to fly while bypassing a loop orbit and mass analyzed to create a mass spectrum. Among the peaks appearing on the mass spectrum, peaks complying with predetermined conditions are extracted to determine a plurality of mass ranges to be measured (S1 through S3). Next, the ion selection conditions for the timing when ions should be injected into the loop orbit and on the loop orbit are determined for each mass range. In addition, deviation conditions under which selected ions will not be mixed are determined (S4 and S5). When the second measurement is performed for the same sample, ions are put into the loop orbit and unnecessary ions are removed from the loop orbit in accordance with the ion selection conditions (S6 and S7). Thus, only the ions to be measured are left on the loop orbit with a high mass resolving power.Type: ApplicationFiled: October 30, 2008Publication date: August 11, 2011Applicant: SHIMADZU CORPORATIONInventor: Shinichi Yamaguchi
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Publication number: 20110180705Abstract: A basic ion optical system having a guaranteed capability for the temporal focusing of ions, including sector-shaped electrodes, an injection slit and an ejection slit, is arranged on the same plane. Four or more sets of the basic ion optical systems are arrayed at predetermined intervals in a direction substantially orthogonal to the aforementioned plane. The injection slit on a topmost basic ion optical system plane and the ejection slit on a basic ion optical system plane located immediate below, as well as the injection slit on a bottommost basic ion optical system plane and the ejection slit on a basic ion optical system plane located immediate above, are respectively connected by another type of basic ion optical system having a guaranteed capability for the temporal focusing of ions. The other injection slits and ejection slits are respectively connected by another type of basic ion optical system having a guaranteed capability for the temporal focusing of ions.Type: ApplicationFiled: October 9, 2008Publication date: July 28, 2011Applicant: SHIMADZU CORPORATIONInventor: Shinichi Yamaguchi
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Patent number: 7956320Abstract: A main peak list is created with the data obtained by an MSn analysis (S1), the difference between the mass-to-charge ratio of each product ion listed on this main peak list and that of the precursor ion is calculated (S2), and an auxiliary peak list for forming a virtual peak corresponding to the mass-to-charge ratio difference is created (S3). On the same graph, an MSn spectrum data is created so that each peak listed on the main peak list and each peak listed on the auxiliary peak list are drawn with different display colors (S4), and the MSn spectrum is displayed on the display screen (S5). Consequently, an MSn analysis result for a plurality of precursor ions with different mass-to-charge ratios becomes easy to be compared. In particular, it is possible to easily and visually determine whether or not a fragment having the same mass-to-charge ratio desorbed by a dissociation exists.Type: GrantFiled: May 18, 2006Date of Patent: June 7, 2011Assignee: Shimadzu CorporationInventor: Shinichi Yamaguchi
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Patent number: 7928372Abstract: A mass spectrometer is provided in which ions are favorably introduced into a loop orbit or favorably led out from the loop orbit without affecting the motion of the ions flying along the loop orbit. An ion-introduction orbit 5 is set to correspond to the orbit (ejection orbit portion 4) of ions after being bent by the sector-shaped electric field E1 in the loop orbit 4. When ions are introduced, a voltage applied to the electrode unit 11 is put to zero to release the sector-shaped electric field E1. Then the ions emitted along the ion-introduction orbit 5 fly straight in the electrode unit 11. The direction and position of the ions coming out from the exit end of the electric field is the same as those ions flying along the loop orbit 4. Therefore, there is no need for placing a deflection electrode for introducing/leading-out ions on the loop orbit.Type: GrantFiled: January 18, 2008Date of Patent: April 19, 2011Assignee: Shimadzu CorporationInventors: Shinichi Yamaguchi, Masaru Nishiguchi, Kiyoshi Ogawa, Yoshihiro Ueno
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Publication number: 20110047782Abstract: In a combination of, for example, a rotor having eight magnetic poles and a stator having twelve slots and pulsating components of permeance, which generate a sinusoidal cogging torque having maxima of the same number as the number of poles of the rotor, pressurizing parts arranged in predetermined positions, applying a force at an outer periphery of the stator and directed inwardly cancels the pulsating components of the cogging torque.Type: ApplicationFiled: November 10, 2010Publication date: March 3, 2011Applicant: MITSUBISHI DENKI KABUSHIKI KAISHAInventors: Yukari Toide, Akihiro Daikoku, Masatsugu Nakano, Hideaki Arita, Shinichi Yamaguchi, Moriyuki Hazeyama, Takashi Yoshioka, Tomohiro Kikuchi, Katsumi Hayami, Takashi Miyazaki
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Publication number: 20110042567Abstract: A sample solution containing a sample component is sprayed onto an atmosphere at atmospheric approximately pressure while being applied with electric charge from the tip of a nozzle (1). A sample molecule is released as an ion in a process where charged minute liquid droplets collide with an atmospheric gas and are broken apart, and a solvent is vaporized from the respective liquid droplets. A reflectron (7) in the shape of a half-cut spheroid is arranged in such a manner that a second focal point (F2) is positioned in front of an ion-introducing portion (4) in the spray flow. A discharge electrode (8) is disposed in a position at a first focal point (F1) of the reflectron (7). When pulsed high voltage is applied to the discharge electrode (8), an electric discharge occurs, causing shock waves to be generated. The shock waves reflected on the reflectron (7) are converged on the second focal point (F2).Type: ApplicationFiled: March 17, 2008Publication date: February 24, 2011Applicant: SHIMADZU CORPORATIONInventor: Shinichi Yamaguchi
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Patent number: 7872223Abstract: A laser light is linearly delivered onto the sample 4. The ions generated from the irradiated area are collected, mass-separated in the mass separator 27, and detected by the detector 28. A mass analysis is repeated while moving the sample stage 3 by a predetermined step width in the x-axis direction so that the one-dimensional mass spectrum information of the sample 4 at a certain rotational position is obtained. Additionally, while the sample 4 is rotated by a predetermined angle, the same measurement is repeated for the entire perimeter, so that the one-dimensional mass spectrum information at each rotational position is obtained. Based on the data obtained in this manner, a reconstruction computational processing is performed by the CT method to reconstruct the two-dimensional distribution image for a substance having a certain mass for example and the image is displayed on the display 35.Type: GrantFiled: April 7, 2006Date of Patent: January 18, 2011Assignee: Shimadzu CorporationInventor: Shinichi Yamaguchi
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Publication number: 20100324833Abstract: A product ion spectrum is created on the basis of MS2 analysis data respectively obtained for a parent compound and a metabolite (S1 and S2). Additionally, a neutral loss spectrum, in which the mass of each product ion is replaced with a mass difference between the mass of the product ion and that of a precursor ion, is created (S3). Then, a common peak having the same mass in both the parent compound and the metabolite is extracted (S4), and a complementary peak appearing at a position corresponding to the difference between the mass of the common peak and that of the precursor ion is extracted (S5); the complementary peak corresponding to a common peak located on the product ion spectrum appears on the neutral loss spectrum, while the complementary peak corresponding to a common peak located on the neutral loss spectrum appears on the product ion spectrum.Type: ApplicationFiled: October 22, 2007Publication date: December 23, 2010Applicant: Shimadzu CorporationInventor: Shinichi Yamaguchi
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Patent number: 7849584Abstract: In a combination of, for example, a rotor having eight magnetic poles and a stator having twelve slots and pulsating components of permeance, which generate a sinusoidal cogging torque having maxima of the same number as the number of poles of the rotor, pressurizing parts arranged in predetermined positions, applying a force at an outer periphery of the stator and directed inwardly cancels the pulsating components of the cogging torque.Type: GrantFiled: November 12, 2008Date of Patent: December 14, 2010Assignee: Mitsubishi Denki Kabushiki KaishaInventors: Yukari Toide, Akhiro Daikoku, Masatsugu Nakano, Hideaki Arita, Shinichi Yamaguchi, Moriyuki Hazeyama, Takashi Yoshioka, Tomohiro Kikuchi, Katsumi Hayami, Takashi Miyazaki
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Publication number: 20100312489Abstract: A product ion spectrum is created on the basis of MS2 analysis data respectively obtained for a parent compound and a metabolite (S1 and S2). Additionally, a neutral loss spectrum, in which the mass of each product ion is replaced with a mass difference between the mass of the product ion and that of a precursor ion, is created (S3). Then, a common peak having the same mass on the neutral loss spectrums of both the parent compound and the metabolite is extracted (S4), and a complementary peak appearing on the product ion spectrum of the metabolite is extracted (S5); this peak appears at a position corresponding to the difference between the mass of the common peak and that of the precursor ion. The ion corresponding to the complementary peak is designated as a precursor ion for the next MS3 analysis (S6), and this MS3 analysis is performed (S7).Type: ApplicationFiled: October 23, 2007Publication date: December 9, 2010Applicant: SHIMADZU CORPORATIONInventor: Shinichi Yamaguchi
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Publication number: 20100312487Abstract: In deducing the composition of an unknown metabolite, information on the kind of reaction and the component which is added or dropped is provided, based on the prediction and knowledge on the pathways of metabolism (S5). Then, based on the information, the kind of elements and the maximum value of the increase and decrease in the number of atoms of the elements are computed. In addition, based on the values and the composition of the original substance, the kind of the unknown substance and the possible range of numbers of atoms thereof are obtained (S6 and S7). Using the element's kind and range of numbers as a computational condition, the combination of elements that matches the mass of the unknown metabolite obtained by a mass analysis is searched to deduce the composition of the unknown metabolite (S8). Since the computational condition is fairly limited, the composition can be deduced with a practical amount of computation and with a high degree of accuracy.Type: ApplicationFiled: November 15, 2006Publication date: December 9, 2010Applicant: Shimadzu CorporationInventor: Shinichi Yamaguchi
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Publication number: 20100277026Abstract: A rotary electric machine comprising a rotor (30A) including a plurality of permanent magnets having magnetic poles and a stator (20A) including a plurality of tooth sections each having a front end portion which faces the rotor, wherein the rotor (30A) has a skew structure having a change section in which boundaries between the magnetic poles change with respect to a rotation axis direction, and the front end portion of each of the plurality of tooth sections of the stator (20A) has an auxiliary slot (24A) which is selectively formed in an extending manner at one portion of the front end portion in the rotation axis direction such that substantially a center of the auxiliary slot in the rotation axis direction is opposed to a center of the change section in the rotation axis direction, and no auxiliary slot is formed at portions located on extensions of the auxiliary slot in the rotation axis direction.Type: ApplicationFiled: December 1, 2008Publication date: November 4, 2010Applicant: MITSUBISHI ELECTRIC CORPORATIONInventors: Shinichi Yamaguchi, Hisashi Otsuka, Haruyuki Hasegawa
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Publication number: 20100258716Abstract: A mass analysis is initially performed while applying appropriate voltages to the electrodes so that ions injected through an entrance gate electrode (5) into a loop orbit (3) are guided through approximately one half of the loop orbit (3) and diverted at an exit gate electrode (6) toward an ion detector (7). Based on the intensities of the peaks appearing on a mass spectrum obtained by this mass analysis, one or more objective ions are selected and a time parameter is specified so that the voltage applied to the exit gate electrode (6) changes when none of the ions flying along the loop orbit (3) are passing through the exit gate electrode (6). As a result, the orbit of the objective ions will assuredly changed so that they will be directed toward the ion detector (7) after flying through the loop orbit (3) multiple times. Thus, the mass information of the objective ions can be assuredly obtained.Type: ApplicationFiled: November 11, 2007Publication date: October 14, 2010Applicant: Shimadzu CorporationInventor: Shinichi Yamaguchi
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Publication number: 20100257829Abstract: There are required a honeycomb structure that is excellent in heat resistance and thermal shock resistance and is less likely to undergo thermal decomposition, and also exhibits stable mechanical properties even when subjected to a heat treatment, and a purifying apparatus using the same. The honeycomb structure of the present invention includes a honeycomb structure made from a ceramic body including a crystal of MgTi2O5—Al2TiO5. The purifying apparatus includes a honeycomb structural, and a casing that accommodates the honeycomb structure and has an inlet port and an outlet port, wherein a fluid introduced through the inlet port of the casing is passed through the honeycomb structure and then discharged through the outlet port of the casing.Type: ApplicationFiled: September 26, 2008Publication date: October 14, 2010Applicant: KYOCERA CORPORATIONInventor: Shinichi Yamaguchi
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Publication number: 20100239773Abstract: An aqueous treating solution for an Sn-based plated steel sheet, comprising (A) an organic material, (B) a water-soluble chromium compound, (C) a water-dispersible silica, and water, wherein the organic material (A) is at least one member selected from an oxy-acid with the ratio of hydroxyl group/carboxyl group in one molecule being from 3/1 to 10/1, its lactone form and an oxide derivative thereof, the water-soluble chromium compound (B) does not contain hexavalent chromium, and pH is from 0.7 to 6.0.Type: ApplicationFiled: September 6, 2007Publication date: September 23, 2010Inventors: Shinichi Yamaguchi, Masao Kurosaki, Yasuto Goto, Manabu Kumagai, Kensuke Mizuno, Takumi Kozaki
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Publication number: 20100201210Abstract: A linear motor includes a stator having field poles arranged linearly with opposing polarities arranged in an alternating manner; and a rotor having an armature core with teeth that faces a pole face of the field poles with a gap, and coils wound around the teeth. The stator and the rotor are supported in a slidable manner, a direction perpendicular to a sliding direction of the rotor and in parallel with the pole face is defined as a stacking direction. A head of each of the teeth has an extended portion extended in the sliding direction. At least heads of the teeth arranged at both ends of the armature core along the sliding direction is divided into a plurality of areas along the stacking direction. At least one of extended portions arranged on adjacent areas is extended by a different length along the sliding direction.Type: ApplicationFiled: September 30, 2008Publication date: August 12, 2010Applicant: MITSUBISHI ELECTRIC CORPORATIONInventors: Misa Nakayama, Shinichi Yamaguchi, Koki Naka, Kazumasa Ito, Toshinori Tanaka
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Publication number: 20100195265Abstract: A dielectric ceramic which improves the lifetime characteristics and dielectric breakdown voltage of a laminated ceramic capacitor includes core-shell crystalline grains which have a core-shell structure and homogeneous crystalline grains which have a homogeneous structure. In this dielectric ceramic, the core-shell crystalline grains and the homogeneous crystalline grains are present at an area ratio in the range of 91:9 to 99:1. Preferably, when the mean grain size for the core-shell crystalline grains is represented by R1 and the mean grain size for the homogeneous crystalline grains is represented by R2, the ratio of R2/R1 is 0.8 or more and 3 or less.Type: ApplicationFiled: January 20, 2010Publication date: August 5, 2010Applicant: MURATA MANUFACTURING CO., LTDInventors: Masanori Nakamura, Shinichi Yamaguchi, Toshikazu Takeda
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Patent number: 7763846Abstract: The present invention provides a method and an apparatus for analyzing mass analysis data for easily deducing the structure of an unknown substance, based on data obtained by an MSn analysis. First, the structural formula of a precursor ion of the unknown substance is deduced based on the mass-to-charge ratio of the precursor ion (Step S12), and candidate structures which have the same compositional formula as the compositional formula deduced in Step S12, by combining the structure of the known substance and known structural change patterns (Step S14). Next, fragment ion peaks expected to appear from the candidate structures are deduced (Step S15), and based on the expected fragment ion peaks, the candidate structures are ranked in the order of probability (Step S16). Then, by comparing a mass spectrum of the known substance and that of the unknown substance, a common fragment ion peak is searched. (Step S19).Type: GrantFiled: April 10, 2007Date of Patent: July 27, 2010Assignee: Shimadzu CorporationInventors: Shinichi Yamaguchi, Yusuke Inohana
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Patent number: 7763847Abstract: An ion optical system to form a loop orbit is provided to sufficiently ensure required performance such as ion transmission efficiency while making it easy to design the system by alleviating a space-focusing condition. The loop orbit of the ion optical system is realized so as to satisfy (t|x)=(t|?)=(t|?)=0 as the time-focusing condition and to satisfy ?2<(x|x)+(?|?)<2, and ?2<(y|y)+(?|?)<2 as the space-focusing condition. (x|x) and other similar terms are constants determined by the elements indicated in the parenthesis in a general expression format of the ion optical system. The conditions are substantially alleviated as opposed to the conventional space-focusing condition where each of (x|x), (?|?), (y|y) and (?|?) needs to be ±1. Thus, the parameters to decide the shape of electrodes by which the ion optical system is configured have higher degree of freedom.Type: GrantFiled: July 20, 2007Date of Patent: July 27, 2010Assignees: Shimadzu Corporation, Osaka UniversityInventors: Masaru Nishiguchi, Shinichi Yamaguchi, Michisato Toyoda