Abstract: The invention relates to amino-heteroaryl derivatives having the general Formula I or a pharmaceutically acceptable salt thereof, to pharmaceutical compositions comprising the same, as well as to the use of these derivatives for the treatment of pain, such as neuropathic pain or inflammatory pain.

Abstract: The present invention relates to compounds of formula (I) wherein X, R1, R2, R3, R4 and R5 are as defined herein, which are useful for treating diseases which respond to CXCR2 receptor mediators. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.

Abstract: A dry powder inhaler has a main airflow path including a cyclone chamber (16) having an air inlet and being so shaped that at least a part of the chamber decreases in cross-sectional area in a direction away from the air inlet, so as thereby in use to set up a reverse flow cyclone in the chamber. A bypass airflow path (8) bypasses the cyclone chamber and the main and bypass airflow paths communicate with a mouthpiece (6). The cyclone chamber may be provided by a part (22) which is removable from the rest of the inhaler for regular replacement thereof.

Abstract: A method for centralising and retaining a molded end coil (20) in a magnet former (12) which includes an oversleeve (24) for retaining the end coil in position, the radially outer (A2) surface of the end coil being of lesser diameter than the radially inner surface of the oversleeve.

Abstract: In a method and apparatus for joining a number of superconductive cables to establish electrical connection therebetween, a cup-like member having a base, a sidewall, and an opening to receive electrically conductive ends of said cables is provided. The base of the cup-like member is attached to a holder device. The holder device is attached to a cryogenically cooled surface. The ends of the superconductive cables are connected together within the cup-like member.

Abstract: In a cylindrical superconducting magnet system for magnetic resonance imaging, primary superconducting coils are positioned within an outer vacuum chamber. A thermal radiation shield surrounds the primary superconducting coils. A gradient coil assembly is axially aligned with the primary superconducting coils. A mechanical support assembly is radially positioned outside of the primary superconducting coils and is mechanically attached to the gradient coil assembly by mechanical attachments which pass through through-holes through the outer vacuum chamber and the thermal radiation shield.

Abstract: The invention relates to novel 5-hydroxytryptamine (5-HT) receptor modulator compounds of formula (I); wherein A, B, R1-R5, T, W, X, Y, Z and m are defined herein, to pharmaceutical compositions comprising these compounds and to their use in the treatment of conditions associated with 5-HT action.

Abstract: A primer-less coating composition for facestock comprises: a binder being a water-dispersible polymer; an ethylenically unsaturated compound which is aqueous-dispersible and miscible with or bonded to said water-dispersible polymer, wherein said ethylenically unsaturated compound is able to form a covalent bond with an ink; and a crosslinker, wherein said crosslinker is suitable for binding the coating to the facestock. The coating composition may be applied to a substrate to form a printable film. A printed film in accordance with the invention may be used in a label, for example for use on a container such as a bottle.

Abstract: A primer-less coating composition for facestock comprises: a binder being a water-dispersible polymer; an ethylenically unsaturated compound which is aqueous-dispersible and miscible with or bonded to said water-dispersible polymer, wherein said ethylenically unsaturated compound is able to form a covalent bond with an ink; and a crosslinker, wherein said crosslinker is suitable for binding the coating to the facestock. The coating composition may be applied to a substrate to form a printable film. A printed film in accordance with the invention may be used in a label, for example for use on a container such as a bottle.

Abstract: There is provided an irrigation apparatus. The irrigation apparatus is used to water trees.

Abstract: A primer-less coating composition for facestock comprises: a binder being a water-dispersible polymer; an ethylenically unsaturated compound which is aqueous-dispersible and miscible with or bonded to said water-dispersible polymer, wherein said ethylenically unsaturated compound is able to form a covalent bond with an ink; and a crosslinker, wherein said crosslinker is suitable for binding the coating to the facestock. The coating composition may be applied to a substrate to form a printable film. A printed film in accordance with the invention may be used in a label, for example for use on a container such as a bottle.

Abstract: A primer-less coating composition for facestock comprises: a binder being a water-dispersible polymer; an ethylenically unsaturated compound which is aqueous-dispersible and miscible with or bonded to said water-dispersible polymer, wherein said ethylenically unsaturated compound is able to form a covalent bond with an ink; and a crosslinker, wherein said crosslinker is suitable for binding the coating to the facestock. The coating composition may be applied to a substrate to form a printable film. A printed film in accordance with the invention may be used in a label, for example for use on a container such as a bottle.

Abstract: A primer-less coating composition for facestock comprises: a binder being a water-dispersible polymer; an ethylenically unsaturated compound which is aqueous-dispersible and miscible with or bonded to said water-dispersible polymer, wherein said ethylenically unsaturated compound is able to form a covalent bond with an ink; and a crosslinker, wherein said crosslinker is suitable for binding the coating to the facestock. The coating composition may be applied to a substrate to form a printable film. A printed film in accordance with the invention may be used in a label, for example for use on a container such as a bottle.

Abstract: A primer-less coating composition for facestock comprises: a binder being a water-dispersible polymer; an ethylenically unsaturated compound which is aqueous-dispersible and miscible with or bonded to said water-dispersible polymer, wherein said ethylenically unsaturated compound is able to form a covalent bond with an ink; and a crosslinker, wherein said crosslinker is suitable for binding the coating to the facestock. The coating composition may be applied to a substrate to form a printable film. A printed film in accordance with the invention may be used in a label, for example for use on a container such as a bottle.

Abstract: Disclosed are pumpable-fluid compositions and methods for establishing hydraulic isolation in cemented subterranean wells. The fluid compositions comprise solids-free solutions of water-soluble polymers. Upon entering voids and cracks in the cement sheath and contacting the set-cement surfaces, the fluid gels and forms a seal that prevents further leakage.

Abstract: An adapter for passing messages in a telecommunications infrastructure from a first device to a second device. The adapter comprises a messaging interface, a processor, and a bus interface. The messaging interface is in communication with the first device and is operable to receive a received message in a first messaging format from the first device. The processor is coupled to the messaging interface and is operable to receive the received message from the messaging interface and translate the received message into a common message in a common format. The bus interface is coupled to the processor and is operable to receive the common message from the processor and transmit the common message to the second device through a bus.

Abstract: Devices, methods, and systems capable of an enabling transmission and receipt of secure and non-secure data are discussed in this document. According to some embodiments, a network apparatus can transmit ciphered and unciphered data. The network apparatus transmits a first signal indicating a cipher to be used and transmits a second signal indicating that non-secure data is to be transmitted and received unciphered. The network apparatus can cipher secure data and transmits ciphered-secure data and unciphered-non-secure data. A wireless terminal can receive the first and second signals, the ciphered secure data, and the unciphered non-secure data. The wireless terminal can deciphers the received secure data and does not decipher the received non-secure data. System embodiments can include both network-side and network terminal components. Embodiments of the present invention enable secure transmission of data in concert with efficient processing.

Abstract: An optical cable includes a buffer tube housing at least one optical fiber, a sheath surrounding such buffer tube and at least one longitudinal strength member embedded in the sheath, in which at least one separation element is provided between a portion of the outer surface of the buffer tube and the inner surface of the sheath, laying in an axial plane not containing the at least one strength member.

Abstract: The invention relates to (pyrrolidin-2-yl)phenyl derivatives having the general Formula I wherein R1 is (C1-4)alkyl, halo(C1-4)alkyl, (C1-4)alkyloxy, or halo(C1-4)alkyloxy; R2 is H, (C1-4)alkyl, halo(C1-4)alkyl, (C1-4)alkyloxy, halo(C1-4)alkyloxy or halogen; R3 is H, (C1-4)alkyl or halo(C1-4)alkyl; R4 is H, (C1-4)alkyl or halo(C1-4)alkyl; R5 is H, (C1-4)alkyl or halo-(C1-4)-alkyl; or R4 and R5, when bonded to the same carbon atom, can together with the carbon atom form a spiro(C3-6)cycloalkyl group, optionally substituted with halogen; R6 is H, (C1-4)alkyl, halo(C1-4)alkyl, (C1-4)alkyloxy, halo(C1-4)alkyloxy or halogen; or a pharmaceutically acceptable salt thereof, to pharmaceutical compositions comprising the same, as well as to the use of these (pyrrolidin-2-yl)phenyl derivatives for the treatment of pain, such as neuropathic pain or inflammatory pain.