Abstract: A positive-logic FET switch stack that does not require a negative bias voltage, exhibits high isolation and low insertion/mismatch loss, and may withstand high RF voltages. Embodiments include a FET stack comprising series-coupled positive-logic FETs (i.e., FETs not requiring a negative voltage supply to turn OFF), series-coupled on at least one end by an “end-cap” FET of a type that turns OFF when its VGS is zero volts. The one or more end-cap FETs provide a selectable capacitive DC blocking function or a resistive signal path. Embodiments include a stack of FETs of only the zero VGS type, or a mix of positive-logic and zero VGS type FETs with end-cap FETs of the zero VGS type. Some embodiments withstand high RF voltages by including combinations of series or parallel coupled resistor ladders for the FET gate resistors, drain-source resistors, body charge control resistors, and one or more AC coupling modules.

Abstract: The present invention refers to a method for producing an integrated circuit comprising a Near Field Communication (NFC) chip, a sensor and an antenna, wherein the method comprises the steps of providing an intermediate circuit comprising the NFC chip connected the sensor, for instance a biosensor, and of providing a single side inlay comprising a substrate and the antenna. Afterwards, the intermediate circuit and the single side inlay are mated together so as to connect the NFC chip to the antenna. The present invention also refers to the integrated circuit or tag produced according to this method.

Abstract: A patient tube securement apparatus is disclosed that may be used for oral or nasal intubation of a patient. The apparatus may comprise an endotracheal tube securement apparatus for securing an endotracheal tube to a patient, the apparatus comprising a dermal patch arranged to be positioned on the skin of the patient, and at least one tube holder on the dermal patch. The apparatus may comprise a patient tube securement apparatus for securing a patient tube to a patient, the apparatus comprising a dermal patch arranged to be positioned on the skin of the patient, and at least one tube holder on the dermal patch. Examples are provided in which the tube holder is adjustably mounted on the dermal patch such that the position of the tube holder on the dermal patch can be adjusted without removing the dermal patch from the skin of the patient.

Abstract: The present invention relates to prostate cancer (PC), in particular the identification of certain bacteria in prostate cancer tissues or liquid biopsies and the use of such identification as a prognostic indicator of cancer progression. The present invention also relates to cultures of newly identified bacteria and means for identifying such bacteria in biological samples.

Abstract: The disclosure relates to operating a wind turbine generator during heating operation that includes a rotor and a stator. The stator includes a first three-phase system with three first drivetrains and a second three-phase system with three second drivetrains. The rotor is configured to generate a magnetic field and inject an electric current into the first and second three-phase systems during a rotation with the magnetic field. The first three-phase system includes a first switch for short-circuiting the first drivetrains in a closed state and idling them in an open state. The second three-phase system includes a second switch for short-circuiting the second drivetrains in a closed state and idling them in an open state. The heating operation includes a first phase in which the first switch is switched to the closed state and the second switch is switched to the open state, or vice-versa.

Abstract: The present invention relates to inorganic salts of nicotinamide mononucleotides and compositions of Formula I, useful in the treatment of disorders and diseases associated with deficiencies in NAD+: wherein A, M1, k, R1 and R2 are as described herein.

Abstract: In one implementation, we propose a block-based end-to-end image and video compression method that takes non-overlapping or overlapping split blocks of input images or frames of videos as input. Then, the proposed decoder network reconstructs non-overlapped split blocks of the input. We also introduce an intra prediction method to reduce spatial redundancy in the latent space, i.e., one or more previously decoded latent tensors from neighboring blocks are used as references to predict the current block's latent tensor. Additionally, the decoder can selectively complete the pixel reconstruction process for decoded latent blocks without causing any error drift to neighboring blocks since the prediction is made in the latent space. Enabling and disabling the pixel reconstruction can be signaled by the encoder as metadata in the bitstream or decided at the decoding stage using a computer vision task.

Abstract: The invention provides an anti-CCR9 antibody molecule for use in a method of treatment of cancer in a mammalian subject wherein the anti-CCR9 antibody molecule is administered simultaneously, sequentially or separately with a chemotherapeutic agent selected from the group consisting of: vincristine, docetaxel, paclitaxel, nanoparticle albumin-bound paclitaxel, and vinblastine, wherein said anti-CCR9 antibody molecule and said chemotherapeutic agent are not conjugated together. Also provided are related methods of treatment.

Abstract: Techniques for monitoring cerebral blood metrics such as cerebral blood flow, cerebral blood volume and/or heart rate are provided. In some embodiments, techniques involve a headset with at least one laser configured to emit light into the brain and one or more light detectors such as CMOS sensors that generate information indicative of light reflected from one or more structures within the brain, which can be used to determine the cerebral blood metrics. Each light detector may be positioned within 5 mm of the scalp in some cases.

Abstract: Collet chuck having a plurality of jaws which are radially movable with respect to one another and which, with their clamping faces, form a common receptacle for guiding a rod that is to be machined in a lathe, characterized by a blind hole which is routed in at least one jaw from the outer face, opposite the clamping face of the jaw, in the direction of the clamping face, with a blind-hole bottom which is delimited on the one hand by the clamping face and on the other hand by the blind hole and which, through wear of the clamping face, is configured to effect the formation of a through-hole indicating the wear of the collet chuck.

Abstract: The subject matter described herein is directed to a chimera molecule such as a polypeptide or protein chimera useful for treating or preventing a viral infection or reducing the severity, incidence, or transmissibility of a viral infection, to nucleic acid molecules encoding the polypeptide or protein chimera, and to pharmaceutical compositions containing them. Also, methods of generating such antiviral polypeptide or protein chimera, of generating nucleic acid molecules encoding the antiviral polypeptide or protein chimera, and of generating pharmaceutical compositions containing the same, and methods of using the same for treatment or prevention of a SARS-CoV-2 infection, or to reduce the severity, incidence, or transmissibility of a of a SARS-CoV-2 infection, are described.

Abstract: Techniques for determining stroke risk are provided. In some embodiments, the techniques may involve causing, using one or more light sources disposed on a headset worn by a user, light to be emitted into the head of the user. The techniques may involve obtaining, using one or more light detectors disposed on the headset, information indicative of light reflected from one more structures within the head, wherein a portion of the obtained information spans a time period during which the user was holding their breath. The techniques may involve based on the obtained information, determining one or more cerebral blood metrics. The techniques may involve providing a representation of the one or more cerebral blood metrics as input to a trained machine learning model, and determining a likelihood the user will experience a stroke over a predetermined future time period based on an output of the trained machine learning model.

Abstract: An auto-injector for administering a dose of a liquid medicament (M) is present having a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle. The injector also has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for insertion of the needle through the chassis into an injection site.

Abstract: A computer-implemented method is provided. The method includes generating an augmented reality environment, determining a number of virtual avatars requiring an avatar space within said augmented reality environment, determining a number of physical avatar spaces that are available for occupation within the augmented reality environment, comparing the number of virtual avatars requiring an avatar space to the number of available physical avatar spaces and, when the number of virtual avatars requiring an avatar space within the augmented reality environment is less than or equal to the number of available physical avatar spaces, assigning a different available physical avatar space to each virtual avatar.

Abstract: Various methods and circuital arrangements for biasing one or more gates of stacked transistors of an amplifier are possible where the amplifier is configured to operate in at least an active mode and a standby mode. Circuital arrangements can reduce bias circuit and stacked transistors standby current during operation in the standby mode and to reduce impedance presented to the gates of the stacked transistors during operation in the active mode while maintaining voltage compliance of the stacked transistors during both modes of operation.

Abstract: An example operation includes one or more of determining one or more objects in a transport that may become airborne and altering a portion of the transport to minimize the one or more objects from becoming airborne during a collision.

Abstract: Disclosed are techniques for environment sensing. In an aspect, a transmitter base station determines a configuration for a radio frequency (RF) sensing signal, the configuration determined based at least in part on coordination among a plurality of base stations, and transmits the RF sensing signal to at least one receiver base station based on the configuration. In an aspect, a receiver base station receives a configuration for an RF sensing signal, the configuration determined based at least in part on coordination among a plurality of base stations, receives, from at least one transmitter base station, the RF sensing signal, and detects at least one target object based, at least in part, on reception of the RF sensing signal.

Abstract: A set of headphones has an audio system, a control system with a graphical user interface (GUI) and a digital content management system including a database of digital content, a user authentication system, a processor, and a memory storing executable instructions. The processor is configured to validate a user, download and store digital content upon user authentication, and decrypt and decode the digital content for output via the audio system to an authenticated user. A set of headphones enable one or more users to engage with story content with one or more biometric sensors to capture physiological and emotional responses, such as heart rate, skin conductivity, and/or motion, which are analyzed in real time by one or more of the processors. This adaptive system dynamically modifies the narrative path and content delivery based on the user's responses, creating personalized and immersive storytelling experiences.

Abstract: Grinding apparatus for grinding a substance in the form of beans into powder, including at least one hopper removably connected to a support structure, a grinding device configured to grind the beans, and weighing means for selectively weighing the hopper and the beans present therein.

Abstract: An Operational Technology (OT) device database is trained by interrogating physical OT devices over the data communication network, and from responses, generating a profile for each interrogated physical OT device, each profile comprising at least data used to set up decoy OT devices that are virtualized to mirror each interrogated physical OT device. A list of local physical OT devices running on a remote private network is received from a specific deception appliance on the remote private network. OT device profiles are selected from the OT device database based on the list of local physical OT devices. The selected OT device profiles are transmitted to the specific deception appliance, at the remote private network. The specific deception appliance maintains VM machines for running decoy OT devices, based on the selected OT device profiles, on the remote private network.