Abstract: Disclosed are one or more compounds comprising chemically modified gamma-hydroxybutyrate (GHB), 2-hydroxytetrahydrofuran, and/or 1,4-butanediol, and salts of such compounds (GHB delivering compounds and salts thereof). Also disclosed are compositions comprising at least one GHB delivering compound, or a salt thereof, methods of making such compounds, and methods of using such GHB delivering compounds and compositions. Methods of treatment using the compounds are also disclosed.

Abstract: The disclosed calibration method includes a calibration phantom positioned on an adjustable table on the surface of a mechanical couch, with the phantom's centre at an estimated location for the iso-centre of a radio therapy treatment apparatus. The calibration phantom is then irradiated using the apparatus, and the relative location of the center of the calibration phantom and the iso-centre of the apparatus is determined by analyzing images of the irradiation of the calibration phantom. The calibration phantom is then repositioned by the mechanical couch applying an offset corresponding to the determined relative location of the centre of the calibration phantom and the iso-centre of the apparatus to the calibration phantom. Images of the relocated calibration phantom are obtained, to which the offset has been applied, and the obtained images are processed to set the co-ordinate system of a stereoscopic camera system relative to the iso-centre of the apparatus.

Abstract: A flow improver comprising a plurality of core-shell particles that can be formed by emulsion polymerization. The core of the core-shell particles can include a drag reducing polymer, while the shell of the particles can include repeat units of a hydrophobic compound and an amphiphilic compound. The flow improver can demonstrate increased pumping stability over conventionally prepared latex flow improvers.

Abstract: A method of processing objects using a programmable motion device is disclosed. The method includes the steps of providing an input conveyance system by which input bins of objects may be provided to a processing station that includes the programmable motion device that includes an end effector, perceiving at the processing station identifying indicia representative of an identity of a plurality of objects at an input area of the input conveyance system, grasping the an acquired object using the end effector, moving the acquired object toward an identified processing container using the programmable motion device, the identified processing container being associated with the identifying indicia and said identified processing container being provided as one of a plurality of processing containers at the processing station, and providing an output conveyance system in communication with the processing station, by which processing containers that contain processed objects may be provided.

Abstract: A method of cutting soft tissue in a hand to treat trigger finger involves advancing an introducer shaft into the hand to position a distal end of the introducer shaft beyond a pulley in a finger of the hand, advancing a blade along a guiding channel on an upper surface of the introducer shaft, to position a distal end of the blade at or near the distal end of the introducer shaft, and rotating a cutting surface of the blade to an orientation at or near perpendicular relative to the upper surface of the introducer shaft. The method further involves retracting the blade along the introducer shaft to cut the pulley and removing the introducer shaft and the blade from the hand.

Abstract: A cleaning arrangement (200) for a coating apparatus (100). The coating apparatus has a base (123) for carrying loose material. The base is rotatable to coat the loose material. The cleaning arrangement includes a base-scraping arrangement (127) and further includes a mounting arrangement (131) by which the base-scraping arrangement is mounted to be reversibly lowered, from a coating position, to a scraping position at which the base-scraping arrangement is positioned to scrape buildup from the base.

Abstract: Provided are automated cell culture systems and related in vitro cell culture methods, including for a co-culture of different cell populations having different cell culture conditions. For example, the system may comprise a bioreactor having a plurality of cell culture compartments, the bioreactor having a fluid port fluidly connected to the plurality of cell culture compartments. A pump fluidly connected to the fluid port can provide a cell culture medium to the plurality of culture compartments. A sensor is operably connected to at least one of the plurality of cell culture compartments for measuring at least one cell culture parameter. In this manner, a controller electronically connected the pump and sensor, is configured to automatically adjust a pump flow rate and/or a cell culture gas content to provide a desired steady-state cell culture parameter for facilitating cells interactions and collection of products representative of said interactions.

Abstract: Composite laminates fabricated from one or more respective laminae of composite material (e.g., fiber-reinforced polymers) may be pre-formed and fully cured, yet configured to be selectively conformable to a desired radius of curvature. To repair a damaged composite structure, a plurality of such composite laminates may be bonded together to form a repair part that may be bolted to or otherwise secured to the damaged composite structure, thereby repairing the structure using repair parts that may match the parent material of the damaged composite structure. Methods of forming said repair parts from a plurality of such composite laminates may provide advantages in costs and lead time, over conventional techniques. Kits may include a plurality of such pre-formed and cured composite laminates that may be stacked and combined together in a plurality of different arrangements to create a customizable repair part for a given damaged composite structure.

Abstract: A multilayer film including at least one abuse layer. The abuse layer being a blend of one or more polyamides and an anhydride grafted or maleic anhydride grafted elastomer. Anhydride or maleic anhydride grafted elastomers include ethylene propylene diene monomer, ethylene propylene copolymer, styrene-ethylene-butylene-styrene, ethylene/octene copolymer and blends thereof. A pouch for made from the multilayer film, a method for packaging a food product with the multilayer film are also disclosed.

Abstract: An object processing system is disclosed that includes a plurality of track sections, and a plurality of remotely actuatable carriers for controlled movement along at least portions of the plurality of track sections, each of the actuatable carriers being instructed at any time to move a limited number of track section only.

Abstract: A transimpedance amplifier (TIA) for converting an input current at an input node into an output voltage at an output node, the TIA comprising: a first amplifier stage having a first input coupled to the input node and a first output; a feedback path between the first output and the first input; a second amplifier stage in the feedback path having a second input, the second input coupled to the first output of the first amplifier stage; a feedback resistor in the feedback path coupled between an output of the second amplifier stage and first input of the first amplifier stage; and an output stage, comprising: a load resistor coupled between a reference voltage node and a T-coil, the T-coil comprising first and second inductors coupled in series at an inductor node, the T-coil coupled between the first output and the load resistor, the inductor node coupled to the output node of the TIA.

Abstract: Techniques for enabling access in a multi-assistant speech processing system are described, where a first assistant system may use components of a second assistant system as data processing components. Runtime operational data and user input data related to the first assistant may be kept separate from the processing data and input data related to the second assistant by propagating a first account ID, for user inputs directed to the first assistant, through the processing pipeline, and using a second account for user inputs directed to the second assistant. A mapping between the first account ID and the second account ID may be accessible to a select number of system components. Handoffs between the two assistants are handled in a manner where data related to one assistant is not accessible by the other assistant.

Abstract: Systems and methods are provided for assembling an aircraft. The method includes receiving an upper half barrel section of fuselage that is in a crown up orientation and installing a crown module into the upper half barrel section.

Abstract: The present invention is directed to novel compounds of Formula (I), or a pharmaceutically acceptable salt, solvate or hydrate thereof. Pharmaceutical compositions comprising a compound of Formula (I), or a pharmaceutically acceptable salt, solvate or hydrate thereof, are also described. The invention is also directed to use of the compounds of Formula (I) for treating a condition in a mammal associated with AhR imbalance, such as an inflammatory disease or disorder.

Abstract: A surface-reinforced bitumen roofing membrane includes at least two layers, namely 1) a bitumen compound layer, and 2) a fiber mat, and can optionally include a) an optional bleed blocker layer that is located between the bitumen compound layer and the fiber mat, b) an optional liquid applied coating that partially or fully encapsulates the fiber mat, c) an optional release liner that is releasably positioned on the bottom surface of the bitumen roofing membrane, and/or d) an optional release film that is releasably positioned on the fiber mat surface.

Abstract: Systems and methods are described to determine relationships between one or more components of an isolated execution environment system based on data obtained from a data intake and query system. Based on the determined relationships, an interactive visualization is generated that indicates the hierarchical relationship of the components. In some cases, to illustrate the relationship between components of the isolated execution environment system, the visualization can include one or more display objects displayed in a subordinate or superior relationship to other display objects. In certain cases, based on an interaction with a display object, the system can generate a query and/or display additional information and/or visualizations based on the results of the query.

Abstract: An electronic aiming system includes an electro-mechanical reticle having a plurality of electrically powered holdover indicators disposed on a primary crosshair of the reticle, the holdover indicators configured to be individually selected and energized to a visible state, a rangefinder configured to generate range data, a computing device configured to generate ballistics data; and a processor configured to receive the range data and ballistics data, select, based at least in part on either or both of the range data and ballistics data, one or more of the holdover indicators, and energize the selected holdover indicator or indicators to the visible state.

Abstract: Disclosed are flexible fluid reservoirs including a front sheet and a back sheet, each comprising a four-layer insulated wall. The four-layer insulated wall includes an interior layer and an exterior layer, and a metallic film layer and an insulation layer disposed between the interior layer and the exterior layer where the metallic film layer is oriented toward the exterior layer and the insulation layer is oriented toward the interior layer. One or more of the interior or exterior layers can be a metallocene modified polyethylene film. The metallic film layer can be aluminum coated polyethylene terephthalate resin. The insulation layer can be a foam layer comprising closed cell polyethylene resin. The four-layer insulated wall can resist or limit temperature changes of a fluid disposed within the reservoir for a period of time. The insulated fluid reservoirs can include closure mechanisms for sealing an upper opening of the reservoir.

Abstract: Methods, apparatus, devices, subsystems, and systems for holographically displaying three-dimensional objects are provided. In one aspect, a device includes at least one processor and at least one memory coupled to the at least one processor and having instructions executable by the at least one processor to perform operations including: obtaining primitive data of a plurality of primitives corresponding to at least one object based on information of the plurality of primitives, the information of the plurality of primitives comprising respective primitive identifiers of the plurality of primitives; for each primitive of the plurality of primitives, determining an electromagnetic (EM) field contribution to each of a plurality of display elements of a display based on primitive data of the primitive; and for each of the plurality of display elements of the display, generating a sum of the EM field contributions of the plurality of primitives to the display element.

Abstract: A system for refining a six degrees of freedom pose estimate of a target object based on a one-dimensional measurement includes a camera and a range-sensing device. The range-sensing device is configured to determine an actual distance measured between the range-sensing device and an actual point of intersection. The range-sensing device projects a line-of-sight that intersects with the target object at the actual point of intersection. The system also includes one or more processors in electronic communication with the camera and the range-sensing device and a memory coupled to the processors. The memory stores data into one or more databases and program code that, when executed by the processors, causes the system to predict the six degrees of freedom pose estimate of the target object. The system also determines a revised six degrees of freedom pose estimate of the target object based on at least an absolute error.