Abstract: The presently disclosed invention relates to devices and methods for conducting bone surgery on an animal using a bone surgery tool comprising a base, a fixed arm fixed to the base, the fixed arm including a shoulder and a jaw, a sliding arm releasably fixable to the base, the sliding arm including a head that receives an implant and a cartridge in a slot, the method comprising hooking the bone with the jaw, moving the head toward the jaw capturing the bone, accessing the bone with a drill through cartridge bores in the cartridge, and drilling holes, accessing the bone with a self-shearing screw attached to a screw driver through cartridge bores in the cartridge, and attaching the implant to the bone, and moving the head away from the jaw releasing the bone.

Abstract: A high-voltage protection module for a metrology device includes a metal-oxide varistor (MOV) coupled across a mains power line, a resistor electrically coupled to the MOV in series with the MOV, and a fuse electrically coupled to the MOV and the resistor in series, the resistor being located between the fuse and the MOV. The fuse opens upon an overvoltage event disengaging alternating current (AC) power from the mains power line to the metrology device.

Abstract: An inventory of Internet-facing assets related to a username within a social media site is generated using network data gathered from network data sources. Using data sources of known threats, such as malware, phishing attempts, scam pages, blacklisted sites, and so on, a network analytic system generates analytical information about components that are owned, managed, and/or controlled by a target entity. A measure of identity threat is generated based on a classification model using the analytical information.

Abstract: The present invention relates to a microfluidic assay system and associated reading device, as well as the individual components themselves. The present invention also relates to methods of conducting assays, using a disposable system and associated reading device, as well as kits for conducting assays.

Abstract: Therapeutics and methods for treating a stroke in a human comprising administering a therapeutic to the patient, wherein the therapeutic comprises one of immortalized human placenta mesenchymal stem cells (hPMSCs) and a product from the immortalized hPMSCs. Methods and therapeutic products comprising extracellular vesicles (EVs) isolated from of immortalized hPMSCs. Therapeutics and methods of treating COVID-19 disease vascular injury comprising administering a therapeutic to the patient, wherein the therapeutic comprises one of hPMSCs and a product from the hPMSCs.

Abstract: An automatic door handle/panel sanitizer dispensing assembly comprising a frame, a control unit including a processor, an actuator assembly controlled by the processor, the actuator assembly includes one of a pump and a valve, a first sensor operatively connected to the processor, a power storage unit powering the control unit, the actuator assembly, and the first sensor, a first nozzle and a second nozzle, both fluidly connected to the actuator assembly, a container coupled to the frame, for storing disinfectant, a threaded hook to hang the assembly onto the door handle, a tray having an arcuate shape and being arranged abutting a roof of the frame and being supported by the frame, a plurality of threaded tray holes extending through the tray arranged proximate to a rear end of the tray.

Abstract: A method for fabricating a cantilever having a device surface, a tapered surface, and an end region includes providing a semiconductor substrate having a first side and a second side opposite to the first side and etching a predetermined portion of the second side to form a plurality of recesses in the second side. Each of the plurality of recesses comprises an etch termination surface. The method also includes anisotropically etching the etch termination surface to form the tapered surface of the cantilever and etching a predetermined portion of the device surface to release the end region of the cantilever.

Abstract: Functionality is disclosed for providing status updates for email threads. A personal information management (PIM) server application receive a first message and a second message. The PIM server application can extract a first status value from the first message and a second status value from the second message, and can generate a status notification message that includes one or both of the first status value or the second status value. The PIM server application can also receive a third message subsequent to the first and second messages, and extract a third status value from the third message. Subsequently, the status notification message can be updated by replacing the first status value or the second status value with the third status value in the status notification message. In this manner, the status notification message can provide a consolidated view of the latest status of multiple email threads.

Abstract: Therapeutics and methods of treating COVID-19 in a patient in need thereof comprising administering a pharmaceutical composition containing a pharmaceutically effective dose of a therapeutic, wherein the therapeutic contains both an ACE2 externalizer and one or more ACE2 internalization preventors. Methods of treatment and pharmaceutical compositions comprising an ACE2 externalizer and one or more ACE2 internalization preventors.

Abstract: A method of diagnosing Alzheimer's disease and related dementias (ADRD) in a patient comprising obtaining a plasma sample from the patient; determining a level of a biochemical sulfide in the plasma sample from the subject by trapping volatilized H2S in the plasma sample using alkaline buffer with monobromobiamine, and detecting the level of biochemical sulfide in the plasma sample, the biochemical sulfide being one of acid-labile sulfide, bound sulfide, and total sulfide; and diagnosing the patient with ADRD when the level of the biochemical sulfide is at least an elevated threshold level for the biochemical sulfide.

Abstract: A waveguide display system may include an eyepiece waveguide that can have a first surface and a second surface, the waveguide including an incoupling diffractive optical element (DOE) and an outcoupling DOE. The waveguide display system may include a light source and a scanning mirror, and may include reflective and collimating optical elements. The incoupling DOE can be configured to selectively propagate incident light beams to the outcoupling DOE in the waveguide through total internal reflection (TIR).

Abstract: The present invention relates to methods for detecting an analyte present in a fluid sample using a microfluidic device comprising a detection zone characterized by an optically transmissible portion and reagent(s) associated with a porous matrix, wherein the analyte is detected with an optical detector. The present invention also provides a microfluidic channel and a microfluidic cartridge for use in such a method.

Abstract: A medical device comprising a structure formed of polyvinyl alcohol.

Abstract: An optical scanner includes a cantilevered optical member protruding from the base portion and a transducer assembly comprising one or more piezoelectric actuators coupled to the cantilevered optical member and configured to induce motion of the cantilevered optical member in a scan pattern. In some cases, the cantilevered optical member has a tapered shape with a distal end narrower than a proximal end adjacent to the base portion of the optical scanner. In some cases, the cantilevered optical member has an elongated width along a first plane and includes a plurality of waveguides. The transducer assembly is configured to induce motion of the cantilevered optical member in a second plane orthogonal to the first plane.

Abstract: The present invention relates to a microfluidic assay system and associated reading device, as well as the individual components themselves. The present invention also relates to methods of conducting assays, using a disposable system and associated reading device, as well as kits for conducting assays.

Abstract: Embodiments of the present invention are directed to drug delivery systems, dosage forms and methods for the intranasal administration of Bryostatins for the treatment of neuro-degenerative diseases. Inventions of the present application are directed to the treatment of neuro-degenerative diseases such as Hutchinson Disease, Parkinson's disease, Down syndrome and Alzheimer's disease.

Abstract: An inventory of Internet-facing assets related to a target domain is generated using network data gathered from network data sources. Using data sources of known threats, such as malware, phishing attempts, scam pages, blacklisted sites, and so on, a network analytic system generates analytical information about domains, sub-domains, and components that are owned, managed, and/or controlled by a target entity. A measure of domain identity threat is generated based on a classification model using the analytical information.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for presence determination. Systems can include one or more user devices and terminal devices. A current location may be determined of a user that is associated with a particular space of a plurality of different spaces. A plurality of location results may be calculated, wherein each location result is computed using a distinct process of a plurality of processes; and evaluating the plurality of location results to determine a current space of the user; wherein the determining is performed by one or more of, a particular user device, a terminal device, or a server system.

Abstract: Embodiments of the present invention are directed to methods and dosage forms for treating inflammation and rejection in transplantation injuries with Bryostatin-1, Bryostatin-1 analogs and pharmaceutically acceptable salts thereof.

Abstract: Embodiments of the present invention are directed to methods and dosage forms for treating inflammation and rejection in transplantation injuries with Bryostatin-1, Bryostatin-1 analogs and pharmaceutically acceptable salts thereof.