Abstract: Embodiments of the present invention are directed to methods and dosage forms for treating inflammation and rejection in transplantation injuries with Bryostatin-1, Bryostatin-1 analogs and pharmaceutically acceptable salts thereof.

Abstract: The present disclosure generally relates to web page analysis, and more particularly to a classification system for web pages. The classification system may classify a web page as malicious based upon one or more signatures generated for the web page. For example, the classification system may compare one or more signatures generated for a first web page to one or more signatures generated for a second web page, where the first web page and the second web page are the same web page at different times or different web pages. Based upon a similarity of the signatures, the classification system may output whether the first web page is malicious. For another example, the classification system may include a classification model that is trained based upon one or more signatures for one or more classified web pages. The classification model may output whether the web page is malicious.

Abstract: An assay method and device can perform at least one (e.g., at least two) assays on a single aliquot of a sample liquid. The device can mix a sample liquid with assay reagents including magnetically susceptible particles. The device is configured to create a sample liquid-air interface with the sample liquid. The magnetically susceptible particles can be located (via an applied magnetic field) at the liquid-air interface when a second liquid contacts the interface to form a liquid-liquid interface. The magnetic particles travel across the liquid-liquid interface to the second liquid. The magnetically susceptible particles are configured to trans-port an analyte across the interface into the second liquid. An assay for the analyte is performed in the second liquid. An assay for another analyte can also be performed in the sample liquid.

Abstract: An RF PA and an RF PA protection circuit are disclosed according to one embodiment of the present disclosure. The RF PA includes an RF PA bias circuit and an RF PA transistor element. The RF PA transistor element has a first current terminal and a control terminal. The RF PA protection circuit is coupled between the RF PA bias circuit and the first current terminal. The RF PA protection circuit reduces a current through the first current terminal using the RF PA bias circuit when a magnitude of a voltage at the first current terminal exceeds a protection threshold.

Abstract: In one embodiment, entries in a database journal in a non-interactive mode can be partially flushed to maintain database performance. In particular, data records that require decryption prior to flushing a database journal entry can be bypassed in non-interactive mode, while data records that need not be decrypted can be flushed. For example, entries that relate to a creation or deletion of a data record can be performed, while entries relating to modification of an existing record can be bypassed and processed during an interactive mode of operation. Other embodiments also include a transformation of the database journal using a filter so that multiple entries to a same record can be combined.

Abstract: In one embodiment, a system uses a two-layer deterministic function, such as a hashing mechanism, to ensure session stickiness or affinity. A client can generate a session key that can be used for at least two things. First, a load balancer can be selected by the client using the session key by using a consistent or deterministic hashing algorithm so that the same load balancer is selected from a set of weighted load balancers. After selecting the load balancer, the client can send the request to the selected load balancer. The load balancer then uses the same session key, which can be transmitted in an HTTP header, to select a backend host server computer. The result is that session affinity is maintained.

Abstract: The presently claimed invention relates to materials and methods for diagnosing a chronic inflammatory disease in a patient comprising testing a biological sample from the patient for a level of a first neurovascular biomarker of lymphatic activation and diagnosing the patient as having the chronic inflammatory disease if the tested level of the first neurovascular biomarker of lymphatic activation is less than a first normal level.

Abstract: Techniques that optimize performance of simultaneous localization and mapping (SLAM) processes for mobile devices, typically a mobile robot. In one embodiment, erroneous particles are introduced to the particle filtering process of localization. Monitoring the weights of the erroneous particles relative to the particles maintained for SLAM provides a verification that the robot is localized and detection that it is no longer localized. In another embodiment, cell-based grid mapping of a mobile robot's environment also monitors cells for changes in their probability of occupancy. Cells with a changing occupancy probability are marked as dynamic and updating of such cells to the map is suspended or modified until their individual occupancy probabilities have stabilized.

Abstract: Techniques that optimize performance of simultaneous localization and mapping (SLAM) processes for mobile devices, typically a mobile robot. In one embodiment, erroneous particles are introduced to the particle filtering process of localization. Monitoring the weights of the erroneous particles relative to the particles maintained for SLAM provides a verification that the robot is localized and detection that it is no longer localized. In another embodiment, cell-based grid mapping of a mobile robot's environment also monitors cells for changes in their probability of occupancy. Cells with a changing occupancy probability are marked as dynamic and updating of such cells to the map is suspended or modified until their individual occupancy probabilities have stabilized.

Abstract: A medical imaging data processing apparatus for identifying an interface between anatomical features comprises a receiving unit configured to receive first medical imaging data that represents a region of a subject at a first time, and second medical imaging data that represents the region of the subject at a second, later time, a registration unit configured to perform a registration procedure to obtain registration data representative of a registration between the first medical imaging data and the second medical imaging data, and an interface identification unit configured to determine a variation of the registration data with location and to identify an interface between an anatomical feature and at least one further anatomical feature based on said variation of the registration data with location.

Abstract: An assay method and device can perform at least one (e.g., at least two) assays on a single aliquot of a sample liquid. The device can mix a sample liquid with assay reagents including magnetically susceptible particles. The device is configured to create a sample liquid-air interface with the sample liquid. The magnetically susceptible particles can be located (via an applied magnetic field) at the liquid-air interface when a second liquid contacts the interface to form a liquid-liquid interface. The magnetic particles travel across the liquid-liquid interface to the second liquid. The magnetically susceptible particles are configured to transport an analyte across the interface into the second liquid. An assay for the analyte is performed in the second liquid. An assay for another analyte can also be performed in the sample liquid.

Abstract: Disclosed is a switching apparatus for an electrical appliance where the switching apparatus includes a plurality of electric switches connected to the electrical appliance. Each electric switch is configured to switch ON/OFF the electrical appliance. A plurality of interconnected ON solenoid devices and a plurality of interconnected OFF solenoid devices are electro-magnetically coupled to ON terminals and OFF terminals of the plurality of electric switches, respectively. Upon flipping an electric switch to an ON operating position a respective OFF solenoid device coupled to the electric switch is de-activated causing de-activation of remaining OFF solenoid devices thereby electro-magnetically flipping remaining electric switches to respective ON operating positions.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for presence determination. One of the methods includes for one or more user devices having one or more associated users, determining a current location of a user, wherein the current location is associated with a particular space of a plurality of different spaces, wherein the determining includes: computing a plurality of location results, wherein each location result is computed using a distinct process of a plurality of processes; and evaluating the plurality of location results to determine a current space of the user; wherein the determining is performed by one or more of, a particular user device, a terminal device, or a server system.

Abstract: A subtractive corrective assay device and methodology, whereby ail required binding and label detection reagents are initially located within the detection zone. Application of a magnetic field is used to selectively remove bound label from the detection zone by means of paramagnetic particles. The relationship between measured label concentration before and after the application of a magnetic field within the detection zone is used to accurately measure analyte concentration within the sample.

Abstract: A medical imaging data processing apparatus for identifying an interface between anatomical features comprises a receiving unit configured to receive first medical imaging data that represents a region of a subject at a first time, and second medical imaging data that represents the region of the subject at a second, later time, a registration unit configured to perform a registration procedure to obtain registration data representative of a registration between the first medical imaging data and the second medical imaging data, and an interface identification unit configured to determine a variation of the registration data with location and to identify an interface between an anatomical feature and at least one further anatomical feature based on said variation of the registration data with location.

Abstract: A subtractive corrective assay device and methodology, whereby ail required binding and label detection reagents are initially located within the detection zone. Application of a magnetic field is used to selectively remove bound label from the detection zone by means of paramagnetic particles. The relationship between measured label concentration before and after the application of a magnetic field within the detection zone is used to accurately measure analyte concentration within the sample.

Abstract: Methods and apparatus for liquid/solid separation for use in applications such as dewatering fine particulate solids, and recovery of valuable metals from ore in a leaching process are provided. One application relates to methods of agitation leaching of metals such as gold from gold-bearing feedstock. A slurry is formed in a tank by agitation, and allowed to settle. A filter bed forms to drain the liquid from the tank, and a vertical screen pipe such as a well point addresses the formation of an impervious film on the upper surface of the filter bed.

Abstract: A network sensor that features a data store and a packet processing engine. Communicatively coupled to the data store, the packet processing engine is configured to (i) generate a retention priority for at least a first flow within a first storage region of a plurality of storage regions and (ii) identify, in response to an eviction request, the priority of each of the plurality of storage regions. The priority of the first storage region is partially based on the retention priority associated with the first flow while the priority of a second storage region is based on retention priorities associated with flows stored within the second storage region. The packet processing engine also is configured to identify, through use of the retention priorities of the stored flows within the first storage region, which flows are to be retained and which flows are to be evicted.

Abstract: A network sensor that features a data store and a packet processing engine. In communication with the data store, the packet processing engine comprises (1) a cache management logic and (2) deduplication logic. The cache management logic is configured to analyze packets to determine whether (a) a packet under analysis include duplicated data and (b) content of the packet is targeted for storage in a same continuous logical storage area as the duplicated data. The deduplication logic, when activated by the cache management logic, is configured to generate a deduplication reference for insertion into the packet prior to storage.

Abstract: Fibrous structures that exhibit a Geometric Mean Overhang Length (GM Overhang Length) of less than 3.65 cm as measured according to the Flexural Rigidity Test Method and/or a Cross-Machine Direction Overhang Length (CD Overhang Length) of less than 3.875 cm as measured according to the Flexural Rigidity Test Method described herein are provided.