Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for presence determination. One of the methods includes for one or more user devices having one or more associated users, determining a current location of a user, wherein the current location is associated with a particular space of a plurality of different spaces, wherein the determining includes: computing a plurality of location results, wherein each location result is computed using a distinct process of a plurality of processes; and evaluating the plurality of location results to determine a current space of the user; wherein the determining is performed by one or more of, a particular user device, a terminal device, or a server system.

Abstract: A subtractive corrective assay device and methodology, whereby ail required binding and label detection reagents are initially located within the detection zone. Application of a magnetic field is used to selectively remove bound label from the detection zone by means of paramagnetic particles. The relationship between measured label concentration before and after the application of a magnetic field within the detection zone is used to accurately measure analyte concentration within the sample.

Abstract: A medical imaging data processing apparatus for identifying an interface between anatomical features comprises a receiving unit configured to receive first medical imaging data that represents a region of a subject at a first time, and second medical imaging data that represents the region of the subject at a second, later time, a registration unit configured to perform a registration procedure to obtain registration data representative of a registration between the first medical imaging data and the second medical imaging data, and an interface identification unit configured to determine a variation of the registration data with location and to identify an interface between an anatomical feature and at least one further anatomical feature based on said variation of the registration data with location.

Abstract: A subtractive corrective assay device and methodology, whereby ail required binding and label detection reagents are initially located within the detection zone. Application of a magnetic field is used to selectively remove bound label from the detection zone by means of paramagnetic particles. The relationship between measured label concentration before and after the application of a magnetic field within the detection zone is used to accurately measure analyte concentration within the sample.

Abstract: A network sensor that features a data store and a packet processing engine. Communicatively coupled to the data store, the packet processing engine is configured to (i) generate a retention priority for at least a first flow within a first storage region of a plurality of storage regions and (ii) identify, in response to an eviction request, the priority of each of the plurality of storage regions. The priority of the first storage region is partially based on the retention priority associated with the first flow while the priority of a second storage region is based on retention priorities associated with flows stored within the second storage region. The packet processing engine also is configured to identify, through use of the retention priorities of the stored flows within the first storage region, which flows are to be retained and which flows are to be evicted.

Abstract: A network sensor that features a data store and a packet processing engine. In communication with the data store, the packet processing engine comprises (1) a cache management logic and (2) deduplication logic. The cache management logic is configured to analyze packets to determine whether (a) a packet under analysis include duplicated data and (b) content of the packet is targeted for storage in a same continuous logical storage area as the duplicated data. The deduplication logic, when activated by the cache management logic, is configured to generate a deduplication reference for insertion into the packet prior to storage.

Abstract: Methods and apparatus for liquid/solid separation for use in applications such as dewatering fine particulate solids, and recovery of valuable metals from ore in a leaching process are provided. One application relates to methods of agitation leaching of metals such as gold from gold-bearing feedstock. A slurry is formed in a tank by agitation, and allowed to settle. A filter bed forms to drain the liquid from the tank, and a vertical screen pipe such as a well point addresses the formation of an impervious film on the upper surface of the filter bed.

Abstract: Fibrous structures that exhibit a Geometric Mean Overhang Length (GM Overhang Length) of less than 3.65 cm as measured according to the Flexural Rigidity Test Method and/or a Cross-Machine Direction Overhang Length (CD Overhang Length) of less than 3.875 cm as measured according to the Flexural Rigidity Test Method described herein are provided.

Abstract: Embodiments of the present invention are directed to the oral administration of Bryostatins for the treatment of neuro-degenerative disease.

Abstract: An assay method and device can perform at least one (e.g., at least two) assays on a single aliquot of a sample liquid. The device can mix a sample liquid with assay reagents including magnetically susceptible particles. The device is configured to create a sample liquid-air interface with the sample liquid. The magnetically susceptible particles can be located (via an applied magnetic field) at the liquid-air interface when a second liquid contacts the interface to form a liquid-liquid interface. The magnetic particles travel across the liquid:liquid interface to the second liquid. The magnetically susceptible particles are configured to transport an analyte across the interface into the second liquid. An assay for the analyte is performed in the second liquid. An assay for another analyte can also be performed in the sample liquid.

Abstract: Embodiments of the present invention are directed to the oral administration of Bryostatins for the treatment of neuro-degenerative disease.

Abstract: Embodiments of the present invention are directed to methods and dosage forms for treating inflammation and rejection in transplantation injuries with Bryostatin-1, Bryostatin-1 analogs and pharmaceutically acceptable salts thereof.

Abstract: Techniques that optimize performance of simultaneous localization and mapping (SLAM) processes for mobile devices, typically a mobile robot. In one embodiment, erroneous particles are introduced to the particle filtering process of localization. Monitoring the weights of the erroneous particles relative to the particles maintained for SLAM provides a verification that the robot is localized and detection that it is no longer localized. In another embodiment, cell-based grid mapping of a mobile robot's environment also monitors cells for changes in their probability of occupancy. Cells with a changing occupancy probability are marked as dynamic and updating of such cells to the map is suspended or modified until their individual occupancy probabilities have stabilized.

Abstract: A subtractive corrective assay device and methodology, whereby ail required binding and label detection reagents are initially located within the detection zone. Application of a magnetic field is used to selectively remove bound label from the detection zone by means of paramagnetic particles. The relationship between measured label concentration before and after the application of a magnetic field within the detection zone is used to accurately measure analyte concentration within the sample.

Abstract: The present invention relates to a microfluidic based assay system, comprising a disposable assay cartridge and associated reading device, as well as the individual components themselves. The present invention also relates to methods of conducting assays, using the cartridge and device of the invention, as well as kits for conducting assays.

Abstract: Fibrous structures that exhibit a Geometric Mean Flexural Rigidity (GM Flexural Rigidity) of less than 40.0 mg*cm2/cm and/or less than 18.0 mg*cm2/cm as measured according to the Flexural Rigidity Test Method described herein and/or a Cross-Machine Direction Flexural Rigidity (CD Flexural Rigidity) of less than 21.0 mg*cm2/cm and/or less than 18.0 mg*cm2/cm and/or less than 17.4 mg*cm2/cm and/or less than 17.25 mg*cm2/cm as measured according to the Flexural Rigidity Test Method described herein are provided.

Abstract: Fibrous structures that exhibit a Geometric Mean Overhang Length (GM Overhang Length) of less than 3.65 cm as measured according to the Flexural Rigidity Test Method and/or a Cross-Machine Direction Overhang Length (CD Overhang Length) of less than 3.875 cm as measured according to the Flexural Rigidity Test Method described herein are provided.

Abstract: A secure electronic financial funds transfer arrangement including: a funds provider entity who issue a voucher to a customer after registration; a customer seeking to purchase goods and services from a merchant utilising electronic means, or other means intending delivery of valuable goods to the registered address; a verification means available to the merchant with the funds provider entity and whereupon said validation of the voucher issued by the funds provider entity to the customer will result in the transfer of financial funds from the funds provider entity to the merchant and the delivery of the selected goods and/or services to the registered address made by the customer during the registration process before the financial funds transfer voucher was issued by the funds provider entity.

Abstract: An assay method and device can perform at least one (e.g., at least two) assays on a single aliquot of a sample liquid. The device can mix a sample liquid with assay reagents including magnetically susceptible particles. The device is configured to create a sample liquid-air interface with the sample liquid. The magnetically susceptible particles can be located (via an applied magnetic field) at the liquid-air interface when a second liquid contacts the interface to form a liquid-liquid interface. The magnetic particles travel across the liquid-liquid interface to the second liquid. The magnetically susceptible particles are configured to trans-port an analyte across the interface into the second liquid. An assay for the analyte is performed in the second liquid. An assay for another analyte can also be performed in the sample liquid.

Abstract: An assay method and device can perform at least one (e.g., at least two) assays on a single aliquot of a sample liquid. The device can mix a sample liquid with assay reagents including magnetically susceptible particles. The device is configured to create a sample liquid-air interface with the sample liquid. The magnetically susceptible particles can be located (via an applied magnetic field) at the liquid-air interface when a second liquid contacts the interface to form a liquid-liquid interface. The magnetic particles travel across the liquid:liquid interface to the second liquid. The magnetically susceptible particles are configured to transport an analyte across the interface into the second liquid. An assay for the analyte is performed in the second liquid. An assay for another analyte can also be performed in the sample liquid.