Abstract: Systems and methods for monitoring for theft of a vehicle component (e.g., a catalytic converter) or another item is provided herein. A monitoring device can be communicatively coupled with a GPS locator and a wireless transceiver such that a location signal can be generated and sent upon certain conditions being met. Preferably, the monitoring device is connected to an external power source and causes the location signal to be generated and sent when there is an interruption in power received from the external power source.

Abstract: Techniques are disclosed relating to improving secure message communication. In various embodiments, a message delivery server receives a request to deliver an encrypted message from a sender to a recipient. The encrypted message obfuscates the identity of the sender such that the message delivery server is unable to determine the identity of the sender. The message delivery server determines whether to deliver the encrypted message based on a signed attestation received with the request and, based on the determining, delivers the encrypted message to the recipient. In some embodiments, the determining includes verifying the signed attestation using a verification key provide by the sender. In some embodiments, the encrypted message is an email, a text message, a push notification, or a video or audio call request.

Abstract: The invention provides a compound of formula (I): or a pharmaceutically acceptable salt thereof, wherein the variables Y1-Y6, X, Z, Z1, Z2, R2-R3, and R6 have the meaning as described herein, and compositions containing such compounds and methods for using such compounds and compositions.

Abstract: An adhesion device incorporates element block assemblies partially disposed within an element support body having an engagement surface. Each element block assembly may include an element activation sheet, an element deployment sheet, a plurality of engagement elements, and an element transition mechanism operatively coupled to the engagement elements. The element transition mechanism is reversible to transition from a neutral configuration wherein the element activation sheet is substantially adjacent to the element deployment sheet, and an expanded configuration wherein the element activation sheet and the element deployment sheet are separated by a transition gap. The element support body, in the neutral configuration, constrains each engagement element in a deployment state with a substantially straightened configuration perpendicular to the engagement surface and suitable for insertion into (or removal from) a target material.

Abstract: Systems, and methods relate to a medical device receiving a treatment parameter operating point within a first operating region defined by a first set of operating points for which automatic incremental adjustment of a parameter in the current operation is permitted. In an illustrative example, incremental adjustment may use artificial intelligence based on patient feedback and sensor measurement of outcomes. Some exemplary devices may receive a request to alter the current treatment parameter operating point to a second treatment parameter operating point outside the first operating region and in a second operating region in a known safe operation zone, bounded by a known unsafe zone unavailable to the user. In the second operating region, some examples may restrict the step size of incremental adjustments requested by the user. Data may be collected for cloud-based analysis, for example, to facilitate discovery of more effective treatment protocols.

Abstract: Methods and system of recording work history of a mining node on a blockchain in a blockchain network. The methods may include mining a first block containing a registration generation transaction that includes, within a registration information field, a miner identifier for the mining node; and mining two or more additional blocks in an order, each additional block containing a generation transaction that includes an information field containing the miner identifier, a reference to the generation transaction of the preceding additional block in the order, wherein the registration generation transaction is a first block in the order. Work history may be verified by tracing the recorded work history and validating the miner identifier. Recorded work history may serve as the basis for a reputation score for the miner, which reflects contributed work evidenced by the proof-of-work secured work history.

Abstract: Described are techniques for electrical grid origination determination using Power Line Disturbance (PLD) characteristics. The techniques include detecting a first PLD in a first voltage feed of a first power unit at a first time. The techniques further include comparing the first PLD to other PLDs aggregated from multiple power units. The techniques further include determining that the first voltage feed of the first power unit originates from a same source as a second power unit based on a similarity between the first PLD and a second PLD of the second power unit satisfying a similarity threshold and occurring within a same timeframe proximate to the first time. The techniques further include recording that the first power unit and the second power unit receive power from a same source.

Abstract: The present invention relates to Ras inhibitors, intermediates in the synthesis thereto, and methods for preparing the Ras inhibitors and the intermediates.

Abstract: Belts and sanitary tissue products of the present disclosure may comprise discrete cells of multiple sizes (including three different cell sizes) and/or certain patterns. The cells may be discrete knuckles or pillows and the fibrous structures may further comprise an emboss, such as a double dot emboss.

Abstract: A vessel hull stabilization system includes a housing having a rotatable shaft mounted thereto, the shaft configured to connect to a fin such that the fin is located on an outside of the vessel hull and the housing is located on an inside of the vessel hull. A drive system is mounted to the housing and includes a motor and a drive element. The motor is connected to a central shaft of the drive element. The drive element includes a plurality of teeth positioned between the outer element and the central shaft such that when the motor rotates the central shaft, the plurality of teeth oscillate inwards and outwards to interact with teeth in the outer element and thereby cause rotation of a fin shaft connected to the outer element or to the gear having the oscillating teeth. A controller receives sensor readings to determine control signals to send to the motor(s) to impart rotation of the fin.

Abstract: Methods and systems are provided to cool an electric machine rotor. The electric machine fluid cooling system includes, in one example, one or more air vents in fluidic communication with one or more radial cooling passages of a rotor shaft. In the system, the radial cooling passages are in fluidic communication with one or more rotor shaft cooling passages that extend through the rotor shaft and an inlet cooling passage.

Abstract: A vegetable slicing shield includes a root, a u-shaped handle, and a plurality of tines. The root is medially disposed between the u-shaped handle and the tines. The u-shaped handle is coupled with the root at opposing lateral regions of a first side of the root. The plurality of tines have first ends coupled with a second side of the root and extending outward from the root to second ends which form a row spaced apart points. Open slots are defined between adjacent tines of the plurality of tines. A subset of the tines are shaped between their first ends and their second ends to form slices of a containment basket which is curved in three-dimensions.

Abstract: The technology is generally directed to reordering packets received by a network to reduce the unfairness in transmitting and receiving data. The packets may be reordered based on a timestamp appended to the packet. The timestamp may correspond to a time when the sender loses control of the packet and the receiving network gains control. A packet reorder structure may receive the packets with the appended timestamps during a sample interval. The packet reorder structure may compare the timestamp to a time interval for a plurality of timeslots. The packets may be reordered based on the timeslot the packet is allocated to. In some examples, the duration of the timeslot may be dynamically adjusted such that the number of out of order packets received during the sample interval corresponds to a threshold.

Abstract: A method of generating a suppression signal using an adaptive filter, using an ear canal microphone signal from an earphone and an audio content signal and combining the suppression signal with others signals to generate a mixed signal that is sent to a speaker.

Abstract: The present invention relates to the combination of soluble ?-glucan and anti-cancer agents that affect the tumor microenvironment. Soluble ?-glucan promotes an immunostimulatory environment, which allows enhanced effectiveness of anti-cancer agents.

Abstract: Bifunctional compounds, which find utility as modulators of leucine-rich repeat kinase 2 (LRRK2), are described herein. In particular, the hetero-bifunctional compounds of the present disclosure contain on one end a moiety that binds to the cereblon E3 ubiquitin ligase and on the other end a moiety which binds LRRK2, such that the target protein is placed in proximity to the ubiquitin ligase to effect degradation (and inhibition) of target protein. The hetero-bifunctional compounds of the present disclosure exhibit a broad range of pharmacological activities associated with degradation/inhibition of target protein. Diseases or disorders that result from aberrant regulation of the target protein are treated or prevented with compounds and compositions of the present disclosure.

Abstract: A packet gateway may protect TCP/IP networks by enforcing security policies on in-transit packets that are crossing network boundaries. The policies may include packet filtering rules derived from cyber threat intelligence (CTI). The rapid growth in the volume of CTI and in the size of associated CTI-derived policies, coupled with ever-increasing network link speeds and network traffic volume, may cause the costs of sufficient computational resources to be prohibitive. To efficiently process packets, a packet gateway may be provided with at least one probabilistic data structure, such as a Bloom filter, for testing packets to determine if packet data may match a packet filtering rule. Packet filtering rules may be grouped into subsets of rules, and a data structure may be provided for determining a matching subset of rules associated with a particular packet.

Abstract: A method of the invention prepares a hydrocarbon-bearing formation for stimulation. A bottom hole assembly comprising a plug and a perforation tool connected to a wireline is lowered into the wellbore. Acid is injected into the wellbore such that the acid is in direct contact with the perforation tool, wireline and casing of the wellbore. The plug is positioned downhole beyond a location where a first perforation area is to be made in the casing. The perforation tool is activated creating the first perforation area. The acid then contacts the first perforation area and cementitious debris generated from the casing being perforated. The perforation tool is next moved up-hole to a second location and the casing is again perforated to create a second perforation area. The acid also contacts the second perforated area and cementitious debris generated from the perforated casing. The perforation tool is lastly removed from the wellbore.

Abstract: A method for determining a disease state prediction, relating to a potential disease or medical condition of a subject, includes accessing a set of subject images, the subject images capturing a part of a subject's body, and accessing a set of clinical factors from the subject. The clinical factors are collected by a device or a medical practitioner substantially contemporaneously with the capture of the subject images. The subject images are inputted into an image data model to generate disease metrics for disease prediction for the subject. The disease metrics generated by the image data model and the clinical factors are inputted into a classifier to determine the disease state prediction, and the disease state prediction is returned.

Abstract: An example method of threshold voltage offset calibration at memory device power up comprises: identifying a set of memory pages that have been programmed within a time window; determining, for each voltage offset bin of a plurality of voltage offset bins, a corresponding value of a data state metric produced by a memory access operation with respect to a memory page of the set of memory pages; identifying a subset of the plurality of voltage offset bins, such that memory access operations performed using the corresponding voltage offsets produced respective values of the data state metric that satisfy a predefined quality criterion; selecting, among the subset of the plurality of voltage offset bins, a voltage offset bin that is associated with the lowest voltage offset; and associating the set of memory pages with the selected voltage offset bin.