Patents by Inventor Steven Josephs

Steven Josephs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20080021032
    Abstract: Disclosed herein are pyrazole glucokinase activators of the formula (I) useful for the treatment of metabolic diseases and disorders, preferably diabetes mellitus.
    Type: Application
    Filed: July 19, 2007
    Publication date: January 24, 2008
    Inventors: Steven Joseph Berthel, Robert Francis Kester, Douglas Eric Murphy, Thomas Jay Prins, Frank Ruebsam, Ramakanth Sarabu, Chinh Viet Tran, Dionisios Vourloumis
  • Patent number: 7320453
    Abstract: Generally, the present invention (referred to also as the “suspension system”) is incorporated in a system for suspending an HVAC unit from one or more wood truss members through the use of one or more top lock plates connected to the wood truss, one or more bottom lock plates connected to the HVAC unit, and one or more suspension chains connected between the top lock plates and the bottom lock plates. The suspension system provides a system for suspending HVAC equipment in residential and light commercial applications that is safer, quicker, cheaper, more reliable and more accurate than systems currently in use.
    Type: Grant
    Filed: February 24, 2005
    Date of Patent: January 22, 2008
    Assignee: Mad Metals, Inc.
    Inventors: Daniel E Berlyn, Ward D. Cole, Bradley Kevin Hall, Steven Joseph Wilkie, Frank Edward Cole
  • Patent number: 7312154
    Abstract: A method of polishing a semiconductor layer formed on a transparent substrate is described, the method including measuring the thickness of the semiconductor from the substrate side of the semiconductor layer simultaneously with the polishing, and using the thickness measurement to modify the polishing.
    Type: Grant
    Filed: December 20, 2005
    Date of Patent: December 25, 2007
    Assignee: Corning Incorporated
    Inventors: Jeffrey Scott Cites, Charles Michael Darcangelo, Steven Joseph Gregorski, Richard Orr Maschmeyer, Mark Andrew Stocker, John Christopher Thomas
  • Patent number: 7305115
    Abstract: A method and system is disclosed to improve the ability of a machine vision system to distinguish desired features of a target by taking images of the target under different one or more lighting conditions and using image analysis to extract information of interest about the target. Ultraviolet light is used alone or in connection with direct on-axis and/or low angle lighting to highlight different features of the target. One or more filters disposed between the target and the camera help to filter out unwanted light from the one or more images taken by the camera. The images may be analyzed by conventional image analysis techniques and the results recorded or displayed on a computer display device.
    Type: Grant
    Filed: February 22, 2002
    Date of Patent: December 4, 2007
    Assignee: Siemens Energy and Automation, Inc.
    Inventor: Steven Joseph King
  • Patent number: 7283374
    Abstract: An extendable enclosure for circuit cards provides the capability for a customer to purchase a low cost system up-front, but still allow for growth.
    Type: Grant
    Filed: February 3, 2005
    Date of Patent: October 16, 2007
    Assignee: Fujitsu Limited
    Inventors: Albert Pedoeem, Mahesh Mistry, Larry Fox, Todd Roccoberton, Tom Chiodo, Willie Braun, Stephen J. Brolin, Steven Joseph Smith
  • Patent number: 7262628
    Abstract: Disclosed is a multi-phase power regulator that accurately senses current at a load in a lossless manner and adjusts the power supplied to the load based on the sensed current. Also disclosed is a method of calibrating a multiphase voltage regulator by applying a known calibration current at the load and determining actual current values by the difference in measured values between when the known calibration current is applied and when it is not applied. The accurate current is determined at a known temperature and accurate temperature compensation is provided by a non-linear digital technique. Each phase of the multi-phase power regulator is individually calibrated so that balanced channels provide accurate power to the load. Also disclosed is a calibration method with minimal noise generation.
    Type: Grant
    Filed: July 2, 2004
    Date of Patent: August 28, 2007
    Assignee: Primarion, Inc.
    Inventors: Scott Wilson Southwell, Benjamim Tang, Robert T. Carroll, Steven Joseph Schulte
  • Patent number: 7262297
    Abstract: The invention relates to pyrimido[5,4-e][1,2,4]triazine-5,7-diamine compounds which are useful for inhibiting protein tyrosine phosphatases, particularly PTP1B, and are useful for lowering blood glucose concentrations in mammals.
    Type: Grant
    Filed: April 30, 2004
    Date of Patent: August 28, 2007
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Steven Joseph Berthel, Adrian Wai-Hing Cheung, Kyungjin Kim, Kshitij Chhabilbhai Thakkar, Weiya Yun
  • Patent number: 7226915
    Abstract: This invention relates to diaminopyrroloquinazoline compounds which are useful for inhibiting protein tyrosine phosphatases, particularly PTP1B, and are useful for lowering blood glucose concentrations in mammals.
    Type: Grant
    Filed: April 30, 2004
    Date of Patent: June 5, 2007
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Steven Joseph Berthel, Kshitij Chhabilbhai Thakkar
  • Patent number: 7135863
    Abstract: A thermal management system and method for cooling Magnetic Resonance Imaging gradient coils. The system includes least one first header tube positioned adjacent to said gradient coils and configured to transport a coolant fluid; at least one set of cooling tubes connected to said header tube at inlet ends and configured to transport said coolant fluid, wherein said cooling tubes are parallel to each other and at least one second header tube positioned adjacent to said gradient coils, connected to said at least one set of cooling tubes at outlet ends of said at least one set of cooling tubes and configured to transport said coolant fluid.
    Type: Grant
    Filed: September 30, 2004
    Date of Patent: November 14, 2006
    Assignee: General Electric Company
    Inventors: Mehmet Arik, Bulent Aksel, William Dwight Gerstler, Cherik Bulkes, Douglas Arthur Kelley, Steven Joseph Brzozowski
  • Patent number: 7082065
    Abstract: A method for and an apparatus in which the FSOURCE connection in a fuse domain is split into multiple nets, allowing flexible placement of primary fuses in the floorplan, is provided. In particular, multiple FSOURCE connections (e.g. C4 pads or wire pads) are provided in the floorplan, allowing flexible placement of primary fuses without additional overhead.
    Type: Grant
    Filed: September 17, 2004
    Date of Patent: July 25, 2006
    Assignee: International Business Machines Corporation
    Inventors: David James Hathaway, Steven Joseph Urish
  • Patent number: 7022313
    Abstract: New compositions formed from the combination of an active substance with a hydrogel carrier moiety are provided. The compositions are suitable for use in high-velocity transdermal particle injection techniques. Methods of providing the new compositions are also provided. In addition, methods for administering pharmacologically active agent to a subject are provided. These methods are useful for delivering drugs, biopharmaceuticals, vaccines and diagnostics agents.
    Type: Grant
    Filed: August 3, 2001
    Date of Patent: April 4, 2006
    Assignee: PowderJect Research Ltd.
    Inventors: Barbara Horsey O'Connor, Terry Lee Burkoth, Steven Joseph Prestrelski, Yuh-Fun Maa, Andrew Muddle, Roderick Hafner
  • Patent number: 6959535
    Abstract: A fuel injector includes an annular main fuel nozzle received within an annular nozzle housing, a main nozzle fuel circuit having at least one annular leg, and a pilot nozzle fuel circuit. Spray orifices of the leg extend through the fuel nozzle and spray wells through the housing are aligned with the orifices. The nozzle is designed to generate sufficient static pressure differentials between at least two different ones of the spray wells to purge the main nozzle fuel circuit. Spray well portions may be asymmetrically flared out with respect to a spray well centerline in different local streamwise directions. Some of the spray well portions may be asymmetrically flared out in a local upstream direction and others in a local downstream direction. The local streamwise direction may have an axial component parallel to a nozzle axis about which the annular nozzle housing is circumscribed and a circumferential component around the nozzle housing.
    Type: Grant
    Filed: January 31, 2003
    Date of Patent: November 1, 2005
    Assignee: General Electric Company
    Inventors: Alfred Albert Mancini, Steven Joseph Lohmueller
  • Patent number: 6863838
    Abstract: Zwitterionic imide compounds are provided according to the formula: R1—SO2—N?—SO2—R2+, where R1 and R2+ are any suitable groups. Typically R1 is a highly fluorinated alkane and R2+ contains a quaternary ammonium group or a heteroatomic aromatic group having an cationic nitrogen, such as: pyridiniumyl, pyridaziniumyl, pyrimidiniumyl, pyraziniumyl, imidazoliumyl, pyrazoliumyl, thiazoliumyl, oxazoliumyl, or triazoliumyl. Zwitterionic liquids are provided, typically having melting points of less than 100° C. and typically having a solubility in water of less than 5% by weight.
    Type: Grant
    Filed: October 25, 2001
    Date of Patent: March 8, 2005
    Assignee: 3M Innovative Properties Company
    Inventor: Steven Joseph Hamrock
  • Publication number: 20040235872
    Abstract: The invention relates to pyrimido[5,4-e][1,2,4]triazine-5,7-diamine compounds which are useful for inhibiting protein tyrosine phosphatases, particularly PTP1B, and are useful for lowering blood glucose concentrations in mammals.
    Type: Application
    Filed: April 30, 2004
    Publication date: November 25, 2004
    Inventors: Steven Joseph Berthel, Adrian Wai-Hing Cheung, Kyungjin Kim, Kshitij Chhabilbhai Thakkar, Weiya Yun
  • Publication number: 20040229890
    Abstract: This invention relates to diaminopyrroloquinazoline compounds which are useful for inhibiting protein tyrosine phosphatases, particularly PTP1B, and are useful for lowering blood glucose concentrations in mammals.
    Type: Application
    Filed: April 30, 2004
    Publication date: November 18, 2004
    Inventors: Steven Joseph Berthel, Kshitij Chhabilbhai Thakkar
  • Publication number: 20040208846
    Abstract: The present invention provides a method for treating a disorder such as hemophilia. A method of treating hemophilia in a mammal by administering recombinant virus virions comprising a nucleotide sequence having an adenoviral inverted terminal repeat fusion sequence, a packaging signal, a transcriptional control region, and a nucleic acid encoding a therapeutic protein such as FVIII. In addition, the DNA molecule does not encode an adenoviral protein. It is preferred that the virions be administered to the mammal under conditions that result in the expression of the therapeutic protein at a level that provides a therapeutic effect in said mammal.
    Type: Application
    Filed: June 15, 2004
    Publication date: October 21, 2004
    Inventors: Wei-Wei Zhang, Ramon Alemany, Yifan Dai, Steven Josephs, Cristina Balague, David Ayares, Richard Schneiderman
  • Publication number: 20040204962
    Abstract: An automatic patient compliancy monitoring method includes communicating a patient compliancy data generating device and a charging and communication station; transmitting patient compliancy data to the charging and communication station; charging the patient compliancy data generating device with the charging and communication station; communicating the charging and communication station and a central server; transmitting patient compliancy data from the charging and communication station to a central server; communicating the central server and a clinician computer; transmitting patient compliancy data from the central server to a clinician computer; and generating a patient use report from the patient compliancy data.
    Type: Application
    Filed: February 10, 2004
    Publication date: October 14, 2004
    Inventors: Steven Joseph Howser, Tommy Mel Simonis
  • Publication number: 20040158001
    Abstract: A method is provided for making aromatic-imide and aromatic-methylidynetrissulfonyl species by reaction of aromatic species with a reactant according to formula (I):
    Type: Application
    Filed: January 26, 2004
    Publication date: August 12, 2004
    Applicant: 3M Innovative Properties Company
    Inventor: Steven Joseph Hamrock
  • Publication number: 20040148938
    Abstract: A fuel injector includes an annular main fuel nozzle received within an annular nozzle housing, a main nozzle fuel circuit having at least one annular leg, and a pilot nozzle fuel circuit. Spray orifices of the leg extend through the fuel nozzle and spray wells through the housing are aligned with the orifices. The nozzle is designed to generate sufficient static pressure differentials between at least two different ones of the spray wells to purge the main nozzle fuel circuit. Spray well portions may be asymmetrically flared out with respect to a spray well centerline in different local streamwise directions. Some of the spray well portions may be asymmetrically flared out in a local upstream direction and others in a local downstream direction. The local streamwise direction may have an axial component parallel to a nozzle axis about which the annular nozzle housing is circumscribed and a circumferential component around the nozzle housing.
    Type: Application
    Filed: January 31, 2003
    Publication date: August 5, 2004
    Inventors: Alfred Albert Mancini, Steven Joseph Lohmueller
  • Publication number: 20040151779
    Abstract: This invention relates to stable non-aqueous formulations which are suspensions of proteinaceous substances or nucleic acids in non-aqueous, anhydrous, aprotic, hydrophobic, non-polar vehicles with low reactivity. More specifically, the present invention relates to stable protein or nucleic acid formulations wherein the compound remains in stable, dry powder form, yet the formulation is flowable and, therefore amenable to delivery to an animal via injection transdermal administration, oral delivery or using an implantable device for sustained delivery. These stable formulations may be stored at elevated temperatures (e.g., 37° C.) for long periods of time and are especially useful as flowable formulations which can be shipped and/or stored at high temperatures or in implantable delivery devices for long term delivery (e.g., 1-12 months or longer) of drug.
    Type: Application
    Filed: January 22, 2004
    Publication date: August 5, 2004
    Applicant: Alza Corporation
    Inventors: Victoria Knepp Maskiewicz, Steven Joseph Prestrelski, Jessica G. Smith, Manley T. Huang