Abstract: The invention provides non-crosslinked and crosslinked block copolymers comprising at least one block A comprising repeating units derived from monomers comprising one or more C1-C3 alkyl (meth)acrylamides and/or (meth)acrylates and at least one block B comprising repeating units derived from monomers comprising one or more C4-C40 alkyl (meth)acrylamides. The invention further provides compositions comprising the block copolymers and applications thereof in various industrial areas including personal care. The invention furthermore provides compositions comprising colloidal particles of the block copolymers. The variables x, y, R1, and R2 are described herein.

Abstract: Using a graphical user interface (GUI), a user is guided to generate a logical graph that represents how real data is generated in a situation. The situation is simulated using an artificial intelligence (AI) model a number of times by having the AI model choose paths through the logical graph to generate synthetic data that is representative of the real data. The AI model may also use a reward table that the user is guided to generate via the GUI to execute the simulation, wherein the reward table incentivizes certain paths of the logical graph, and agents of the AI model are trained using the values of this reward table. This synthetic data generated via the AI model can be used for training other AI models.

Abstract: The invention provides for bifunctional molecules comprising an Rpn11 binding partner and a target protein binding partner. A bifunctional molecule according to the invention binds to Rpn11 and to the target protein, thereby facilitating degradation of the target protein bound to the target protein binding partner. The invention also provides for use of a bifunctional molecule for preventing or treating disease.

Abstract: A display includes two-integrated cameras. A first camera is situated in a top right corner of a front display surface of the display and a second camera is situated in a top left corner of the front display surface. The display is connected to a transaction terminal with the first camera focused on a bagging area associated with the transaction terminal and with the second camera focused on a staging area associated with the transaction terminal. Each camera captures images of items and the item images are streamed over a high-speed display port directly to the transaction terminal. The transaction terminal performs item recognition, item tracking, and auditing on the items based the item images during transaction processing at the transaction terminal.

Abstract: An example playback device includes programming for executing functions including, while connected to both (i) a local area network and (ii) an audio playback network configured separately from the local area network and arranged for playback of media content via at least the playback device, receiving from a network device via the local area network, a request for the network device to connect to the audio playback network. The functions also include, in response to the request, transmitting to the network device via the local area network, a message indicating an identifier of the audio playback network and a password for accessing the audio playback network. The functions also include exchanging one or more messages with the network device via the audio playback network to authenticate the network device for the audio playback network and receiving an audio playback command from the network device via the audio playback network.

Abstract: Systems and methods of the present disclosure enable variable and dynamic feedback to electronic activities by receiving event data and utilizing a feedback machine learning model to predict an average feedback attribute and an average feedback variability attribute based on the event data. A feedback data entry is added to a user profile to store the average feedback attribute and the average feedback variability attribute. A new event and a new event attribute are received for the user profile, and a feedback probability distribution for the new event is generated based on the new event attribute, the average feedback attribute, and the average feedback variability attribute. A new event feedback is generated for the new event based on a random selection from the feedback probability distribution and is output to a computing device associated with the user profile.

Abstract: A method for changing a set point of a system where period of a dominant resonance of the system is determined, a change profile for the set point change is processed; a time period for the set point change based on the period of the dominant resonance in order to minimize excitation of the dominant resonance is also processed; and the set point change is actioned according to the processed change profile and the time period.

Abstract: The invention provides a process for removal of a thio-based end group from a polymer comprising repeating units derived from at least one monomer comprising at least one acryloyl moiety and at least one functionalized or unfunctionalized lactam moiety by subjecting the polymer to radiation in a reaction medium devoid of any chemical reagent. Exemplary process involves removal of thio-based end groups from polymers prepared by reversible addition-fragmentation chain transfer polymerization of at least one monomer comprising at least one acryloyl moiety and at least one functionalized or unfunctionalized lactam moiety by exposing the polymer to visible radiation in a reaction medium devoid of any chemical reagent.

Abstract: The invention provides a method for preparation of homopolymers and non-homopolymers comprising polymerizing in an aqueous medium a monomer comprising at least one acryloyl moiety and at least one functionalized or unfunctionalized lactam moiety, and optionally at least one hydrophilic or hydrophobic comonomer, in the presence of at least one chain transfer agent and at least one non-radiation initiator. Exemplary diblock polymers prepared by the method have the structure: where subscripts x, y, and z and variables R, R8, R9 and R10 are described herein.

Abstract: A method for outputting recommendations for energy efficient operation of a vehicle having at least two modes of operation, from which an operating mode is respectively selected by a drive controller, depending on the occurrence of specified triggers, for operating the vehicle. A change of operating mode caused by the trigger is determined. A frequency of the change of operating mode is incremented at every determination of the change of operating mode caused by the trigger. The frequency is analyzed by comparing the frequency of the change of operating mode a predetermined value. A message is generated on a case-by-case basis. The message is output via at least one output comprised by the vehicle.

Abstract: The present invention relates to specific types of pharmaceutical formulations and compositions comprising cannabinoids for use in the treatment of various disorders.

Abstract: The present invention relates to specific types of pharmaceutical formulations and compositions comprising cannabinoids for use in the treatment of various disorders.

Abstract: A compound of formula (I) wherein n is 0 to 4; m is 0 or 1 with the proviso that the sulphur atom and R3 are in vicinal position (if m=0 then R3 is in position 2?, and if m=1 then R3 is on position 1?); R is ethyl or vinyl; R1 is hydrogen or (C1-6)alkyl, R2 is hydrogen or (C3-6)cycloalkyl, or unsubstituted (C1-6)alkyl, or (C1-6)alkyl substituted by one or more of hydroxy; preferably one or two, methoxy, halogen, (C3-6)cycloalkyl, or R1 and R2 together with the nitrogen atom to which they are attached form a 5 to 7 membered heterocyclic ring containing at least 1 nitrogen atom or 1 nitrogen and 1 additional heteroatom e. g. selected from N or O, or R1 is hydroxy and R2 is formyl; R3 is OH, OR4, a halogen atom, or R3 is bound to 2? and represents —O—(CH2)p—O— with p is 2 or 3; R4 is unsubstituted (C1-6)alkyl or (C3-6)cycloalkyl, or a pharmaceutically acceptable salt, solvate, prodrug or metabolite thereof for the specific use in the treatment or prevention of a disease mediated by a virus.

Abstract: A medical device includes a handle; flexible tubing extending from the handle and having a proximal end fixed to the handle; flexible tip attached to the distal end of the flexible tubing; a tip actuator assembly adjusting the bending plane of the tip relative to the distal end and adjusting the degree of bending of the tip in the bending plane; user operable controls on the handle and moveable in a first, rotational direction relative to the handle and to a tip actuator assembly around an axis causing the tip actuator assembly to adjust the bending plane of the tip substantially and moveable relative to the handle and the tip actuator assembly along a second, substantially linear direction towards and away from the proximal end of the flexible tubing, causing the tip actuator assembly to adjust bending of the tip in the bending plane without adjusting the bending plane.

Abstract: A method for outputting recommendations for energy efficient operation of a vehicle having at least two modes of operation, from which an operating mode is respectively selected by a drive controller, depending on the occurrence of specified triggers, for operating the vehicle. A change of operating mode caused by the trigger is determined. A frequency of the change of operating mode is incremented at every determination of the change of operating mode caused by the trigger. The frequency is analyzed by comparing the frequency of the change of operating mode a predetermined value. A message is generated on a case-by-case basis. The message is output via at least one output comprised by the vehicle.

Abstract: A method adapts vehicle functionality that is automatically carried out by an assistance system. In a method in which misunderstandings between driver and vehicle are prevented in predetermined driving situations, when the driver aborts the automatically carried out functionality, this abortion is recorded and saved. If the abortion frequency exceeds a predetermined threshold value, the aborted functionality is replaced by a modified or new functionality.

Abstract: A device for operating a seating arrangement that can be folded out of or into a vehicle. Includes a control unit that receives and executes an activation command by an authorized vehicle user and third parties for folding the seating arrangement out of a region inside the vehicle into a region accessible from outside the vehicle.

Abstract: An apparatus for producing a three-dimensional object by spray deposition including a powder conveyance line A arranged to channel a flow of spray material entrained in a carrier gas to a nozzle (a first flow). The apparatus also has a process line B arranged to channel a flow of gas to the nozzle (a second flow). The apparatus also has a spray nozzle. The apparatus is such that pressure and temperature parameters of the first flow are controlled in real time, but for the second flow these parameters are not controlled in real time. The two flows merge to cause spray material to be propelled from the nozzle to a substrate to create a three-dimensional object.

Abstract: A method of 3D printing an item, includes printing part of the item in three dimensions on a substrate, reorienting the part with respect to holding means that holds the part or substrate, and printing a further part of the item in three dimensions on the first mentioned part.