Patents by Inventor SuPing Lyu

SuPing Lyu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20150367055
    Abstract: Methods and related apparatuses for sorbent recharging are provided. The methods and related apparatuses for recharging can recharge a specific rechargeable layer of a sorbent material such as zirconium phosphate in a sorbent cartridge. The methods and apparatuses include passing solutions containing combinations of acids, bases and salts through a module containing a rechargeable sorbent material such as zirconium phosphate in order to replace ions bound to the zirconium phosphate with hydrogen and sodium ions. The method allows for a customizable zirconium phosphate, with control over the ratios of sodium to hydrogen on the recharged zirconium phosphate.
    Type: Application
    Filed: March 10, 2015
    Publication date: December 24, 2015
    Applicant: Medtronic, Inc.
    Inventors: Bryant J. Pudil, SuPing Lyu, Eric Grovender, Christopher M. Hobot, Martin T. Gerber
  • Publication number: 20150367054
    Abstract: Methods include monitoring indicators of blood pH or blood electrolyte levels during a blood fluid removal session and adjusting concentrations of pH buffers or electrolytes in dialysate or replacement fluid used during the session based on the monitored indicators. Blood fluid removal systems may employ sensors that monitor blood pH or electrolyte levels to adjust the fluid parameters during a blood fluid removal session.
    Type: Application
    Filed: August 18, 2015
    Publication date: December 24, 2015
    Applicant: MEDTRONIC, INC.
    Inventors: Martin Gerber, John Burnes, Suping Lyu, VenKatesh R. Manda, Bryant Pudil
  • Publication number: 20150352269
    Abstract: Methods include monitoring indicators of blood pH or blood electrolyte levels during a blood fluid removal session and adjusting concentrations of pH buffers or electrolytes in dialysate or replacement fluid used during the session based on the monitored indicators. Blood fluid removal systems may employ sensors that monitor blood pH or electrolyte levels to adjust the fluid parameters during a blood fluid removal session.
    Type: Application
    Filed: August 18, 2015
    Publication date: December 10, 2015
    Applicant: MEDTRONIC, INC.
    Inventors: Martin Gerber, John Burnes, Suping Lyu, VenKatesh R. Manda, Bryant Pudil
  • Patent number: 9192707
    Abstract: Methods include monitoring indicators of blood pH or blood electrolyte levels during a blood fluid removal session and adjusting concentrations of pH buffers or electrolytes in dialysate or replacement fluid used during the session based on the monitored indicators. Blood fluid removal systems may employ sensors that monitor blood pH or electrolyte levels to adjust the fluid parameters during a blood fluid removal session.
    Type: Grant
    Filed: March 20, 2012
    Date of Patent: November 24, 2015
    Assignee: Medtronic, Inc.
    Inventors: Martin Gerber, John Burnes, Suping Lyu, Manda R. VenKatesh, Bryant Pudil
  • Publication number: 20150306382
    Abstract: Implantable medical leads include a conductive interconnect within a high frequency shunt that dissipates high frequency current. The conductive interconnect provides an elasticity that allows a drive shaft to rotate and translate during implantation of the lead while the conductive interconnect maintains physical contact with the drive shaft and with a shunt electrode before, during, and after the implantation. The conductive interconnect may provide a low friction that presents a smooth rotation and translation of the drive shaft to provide an acceptable tactile feedback during implantation. The conductive interconnect also provides a high electrical conductivity so that a substantial amount of high frequency current flows through the conductive interconnect to the shunt electrode. The conductive interconnect may include a polymer filler that partially penetrates into the interstitial spaces of the conductive interconnect to assist in maintaining the physical integrity of the conductive interconnect.
    Type: Application
    Filed: April 28, 2014
    Publication date: October 29, 2015
    Applicant: Medtronic, Inc.
    Inventors: Bushan K. Purushothaman, Kenneth C. Gardeski, Suping Lyu, Yaling Fan, Peter M. Seiler
  • Publication number: 20150196867
    Abstract: Frame structures, assemblies and methods for use in implantable medical devices. The frames may include one or more first polymeric portions and one or more second polymeric portions coupled to the one or more first polymeric portions. The one or more first polymeric portions may have a higher durometer than the one or more second polymeric portions. The one or more second polymeric portions may provide an interference fit between the one or more second polymeric portions and the housing and/or between the one or more second polymeric portions and one or more components disposed in the housing.
    Type: Application
    Filed: January 9, 2015
    Publication date: July 16, 2015
    Inventors: Andrew J. Ries, SuPing Lyu, Catherine M. Asgian, David Engmark, Ananta Pandey, Todd Schaefer, Erik Scott, Joachim Hossick-Schott
  • Patent number: 9061099
    Abstract: A method includes initiating a blood fluid removal session for a patient in need thereof; monitoring a cardiovascular parameter of the patient; determining whether the indicator of the cardiovascular state crosses a predetermined threshold; and altering a parameter of the blood fluid removal session if the indicator is determined have crossed the threshold.
    Type: Grant
    Filed: March 20, 2012
    Date of Patent: June 23, 2015
    Assignee: Medtronic, Inc.
    Inventors: Martin Gerber, John Burnes, Suping Lyu, Manda R. VenKatesh, Bryant Pudil
  • Publication number: 20150151033
    Abstract: A method includes initiating a blood fluid removal session of a patient; monitoring an indicator of tissue fluid volume of the patient, or a portion thereof, during the blood fluid removal session; monitoring an indicator of blood fluid volume of the patient during the blood fluid removal session; determining whether a ratio of the indicator of tissue fluid volume to indicator of blood fluid volume is outside of a predetermined range; and altering the rate of fluid removal during the blood fluid removal session if the ratio is determined to be outside of the predetermined range. A blood fluid removal system may be configured to carry out the method.
    Type: Application
    Filed: February 4, 2015
    Publication date: June 4, 2015
    Applicant: MEDTRONIC, INC.
    Inventors: Martin Gerber, John Burnes, Suping Lyu, Manda R. VenKatesh, Bryant Pudil
  • Patent number: 9017277
    Abstract: An implantable dialysis device with a related medical system for intracorporeal dialysis and ultrafiltration of blood, and methods of use are described. The medical system includes an extracorporeal module, a cutaneous module, and an implantable module. Features of the implantable module facilitate delivery and flow of blood and dialysate through the medical system. A filter pack within the implantable module performs dialysis and ultrafiltration of blood. System cleansing is also described.
    Type: Grant
    Filed: May 2, 2012
    Date of Patent: April 28, 2015
    Assignee: Medtronic, Inc.
    Inventors: SuPing Lyu, Thomas Edward Meyer, Mark Fredrick Daniels, Bryant J. Pudil
  • Patent number: 9005634
    Abstract: A pharmaceutical depot includes a biodegradable polymer having a glass transition temperature of 20 degrees centigrade or less and at least 25% wt solid particles suspended in the biodegradable polymer. The pharmaceutical depot also includes a post-operative pain relieving therapeutic agent.
    Type: Grant
    Filed: October 27, 2011
    Date of Patent: April 14, 2015
    Assignee: Medtronic, Inc.
    Inventors: Phillip E. McDonald, Suping Lyu
  • Publication number: 20150088047
    Abstract: A method includes monitoring an indicator of fluid volume of a patient via a sensor device, and setting an initial fluid volume removal prescription for a blood fluid removal session based on the monitored indicator of fluid volume. The method may further include transmitting data regarding the indicator of fluid volume from the implantable sensor device to fluid removal device. The system includes a blood fluid removal device configured to set the initial fluid removal volume and rate prescription. In some embodiments, the fluid removal device sets or calculated the initial fluid volume removal prescription based on the data received from the implantable sensor. The indicator of fluid volume may be an indicator of tissue fluid volume or an indicator of blood fluid volume.
    Type: Application
    Filed: November 26, 2014
    Publication date: March 26, 2015
    Applicant: MEDTRONIC, INC.
    Inventors: Martin Gerber, John Burnes, Suping Lyu, Manda R. VenKatesh, Bryant Pudil
  • Publication number: 20150080682
    Abstract: A method includes monitoring an indicator of fluid volume of a patient via a sensor device, and setting an initial fluid volume removal prescription for a blood fluid removal session based on the monitored indicator of fluid volume. The method may further include transmitting data regarding the indicator of fluid volume from the implantable sensor device to fluid removal device. The system includes a blood fluid removal device and control electronics configured to set the initial fluid removal volume and rate prescription. In some embodiments, the fluid removal device sets or calculated the initial fluid volume removal prescription based on the data received from the implantable sensor. The indicator of fluid volume may be an indicator of tissue fluid volume or an indicator of blood fluid volume.
    Type: Application
    Filed: November 26, 2014
    Publication date: March 19, 2015
    Applicant: MEDTRONIC, INC.
    Inventors: Martin Gerber, John Burnes, Suping Lyu, Manda R. VenKatesh, Bryant Pudil
  • Patent number: 8951219
    Abstract: A method includes initiating a blood fluid removal session of a patient; monitoring an indicator of tissue fluid volume of the patient, or a portion thereof, during the blood fluid removal session; monitoring an indicator of blood fluid volume of the patient during the blood fluid removal session; determining whether a ratio of the indicator of tissue fluid volume to indicator of blood fluid volume is outside of a predetermined range; and altering the rate of fluid removal during the blood fluid removal session if the ratio is determined to be outside of the predetermined range. A blood fluid removal system may be configured to carry out the method.
    Type: Grant
    Filed: March 20, 2012
    Date of Patent: February 10, 2015
    Assignee: Medtronic, Inc.
    Inventors: Martin Gerber, John Burnes, Suping Lyu, Manda R. VenKalesh, Bryant Pudil
  • Patent number: 8926542
    Abstract: A method includes monitoring an indicator of fluid volume of a patient via a sensor device, and setting an initial fluid volume removal prescription for a blood fluid removal session based on the monitored indicator of fluid volume. The method may further include transmitting data regarding the indicator of fluid volume from the implantable sensor device to fluid removal device. In some embodiments, the fluid removal device sets or calculated the initial fluid volume removal prescription based on the data received from the implantable sensor. The indicator of fluid volume may be an indicator of tissue fluid volume or an indicator of blood fluid volume.
    Type: Grant
    Filed: March 20, 2012
    Date of Patent: January 6, 2015
    Assignee: Medtronic, Inc.
    Inventors: Martin Gerber, John Burnes, SuPing Lyu, VenKatesh R. Manda, Byant Pudil
  • Publication number: 20140326671
    Abstract: Disclosed are systems and methods for the performance of kidney replacement therapy having or using a dialyzer, control components, a sorbent cartridge with at least two separate flow paths, and fluid reservoirs configured to be of a weight and size suitable to be worn or carried by an individual requiring treatment. The system for performing kidney replacement therapy has a controlled compliance dialysis circuit, where a control pump controls the bi-directional movement of fluid across a dialysis membrane. The dialysis circuit and an extracorporeal circuit for circulating blood are in fluid communication through the dialysis membrane. The flux of fluid moving between the extracorporeal circuit and the dialysis circuit is modified by the rate at which the control pump is operating such that a rate of ultrafiltration and convective clearance can be controlled.
    Type: Application
    Filed: August 22, 2012
    Publication date: November 6, 2014
    Applicant: Medtronic, Inc.
    Inventors: Thomas D. Kelly, SuPing Lyu
  • Patent number: 8831748
    Abstract: A medical electrical electrode includes an elongated conductive coil located over a lead body, and a conductive polymer material in contact with the lead body and located between individual coils of the elongated conductive coil. In certain embodiments, the conductive polymer is a polymer (e.g., silicone) implanted with a conductive filler (e.g., carbon black). In certain embodiments, the conductive polymer material is generally isodiametric with an outer diameter of the individual coils of the elongated conductive coil. A medical electrical electrode is fabricated by sliding an elongated conductive coil over a length of a lead body, dispersing a conductive polymer on the helical coil, inserting a tubing over the elongated conductive coil, distributing the polymer material between individual turns of the elongated conductive coil, heating the tubing so the tubing shrinks around the elongated conductive coil, and removing the tubing.
    Type: Grant
    Filed: March 30, 2009
    Date of Patent: September 9, 2014
    Assignee: Medtronic, Inc.
    Inventors: Mark T. Marshall, Teresa A. Whitman, Suping Lyu, Elizabeth K. Nagy, David S. Olson
  • Patent number: 8637064
    Abstract: A process for making an implantable material comprising a composite of a biocompatible polymer and a bioactive agent. The composite combines desirable mechanical properties of polymers and the bioactivity of tissue or one or more component of tissue. More particularly, but not exclusively, the invention relates to methods for the manufacture of implantable materials, devices and components via a powder molding process.
    Type: Grant
    Filed: September 20, 2006
    Date of Patent: January 28, 2014
    Assignee: Warsaw Orthopedic, Inc.
    Inventors: SuPing Lyu, Christopher M. Hobot, Sean M. Haddock, Brian A. Loy, Randall V. Sparer, K. Matthew Kinnane, Jeffrey M. Gross
  • Publication number: 20130256227
    Abstract: Sorbent cartridges having a polystyrene sulfonate resin saturated with calcium ions for the performance of kidney replacement therapy are disclosed. Systems and methods having or using a sorbent cartridge, a dialyzer, control components, a cartridge having a polystyrene sulfonate resin, and fluid reservoirs configured to be of a weight and size suitable to be worn or carried by an individual requiring treatment are disclosed. A system for performing kidney replacement therapy has a controlled compliance dialysis circuit, where a control pump controls the bi-directional movement of fluid across a dialysis membrane. The system provides for the monitoring of an inlet and outlet conductivity of the sorbent cartridge to quantify or monitor the removal of urea by the sorbent cartridge.
    Type: Application
    Filed: September 12, 2012
    Publication date: October 3, 2013
    Applicant: MEDTRONIC, INC.
    Inventors: Thomas D. Kelly, SuPing Lyu
  • Publication number: 20130213890
    Abstract: Apparatuses, systems, and methods for the performance of kidney replacement therapy having or using a dialyzer, control components, sorbent cartridge, and fluid reservoirs configured to be of a weight and size suitable to be worn or carried by an individual requiring treatment are disclosed. The system has a controlled compliance dialysis circuit, where a control pump controls the bi-directional movement of fluid across a dialysis membrane. A first sorbent cartridge is provided for use in a portable treatment module having activated carbon and zirconium oxide. The system also provides for the monitoring of an inlet and outlet conductivity of a sorbent cartridge containing urease to provide a facility to quantify or monitor the removal of urea by a detachable urea removal module.
    Type: Application
    Filed: August 15, 2012
    Publication date: August 22, 2013
    Applicant: Medtronic, Inc.
    Inventors: Thomas D. Kelly, SuPing Lyu, Bryant J. Pudil, Thomas E. Meyer
  • Publication number: 20130199998
    Abstract: Systems and methods for the performance of kidney replacement therapy having or using a dialyzer, control components, sorbent cartridge and fluid reservoirs configured to be of a weight and size suitable to be worn or carried by an individual requiring treatment are disclosed. The system for performing kidney replacement therapy has a controlled compliance dialysis circuit, where a control pump controls the bi-directional movement of fluid across a dialysis membrane. The dialysis circuit and an extracorporeal circuit for circulating blood are in fluid communication through the dialysis membrane. The flux of fluid moving between the extracorporeal circuit and the dialysis circuit is modified by the rate at which the control pump is operating such that a rate of ultrafiltration and convective clearance can be controlled. The system provides for the monitoring of an inlet and outlet conductivity of the sorbent cartridge to provide a facility to quantify or monitor the removal of urea by the sorbent cartridge.
    Type: Application
    Filed: August 2, 2012
    Publication date: August 8, 2013
    Applicant: MEDTRONIC, INC.
    Inventors: Thomas D. Kelly, SuPing Lyu, Bryant J. Pudil, Thomas E. Meyer