Patents by Inventor SuPing Lyu

SuPing Lyu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120289881
    Abstract: An implantable dialysis device with a related medical system for intracorporeal dialysis and ultrafiltration of blood, and methods of use are described. The medical system includes an extracorporeal module, a cutaneous module, and an implantable module. Features of the implantable module facilitate delivery and flow of blood and dialysate through the medical system. A filter pack within the implantable module performs dialysis and ultrafiltration of blood. System cleansing is also described.
    Type: Application
    Filed: May 2, 2012
    Publication date: November 15, 2012
    Applicant: Medtronic, Inc.
    Inventors: SuPing Lyu, Thomas Edward Meyer, Mark Fredrick Daniels, Bryant J. Pudil
  • Publication number: 20120277655
    Abstract: A method includes initiating a blood fluid removal session of a patient; monitoring an indicator of tissue fluid volume of the patient, or a portion thereof, during the blood fluid removal session; monitoring an indicator of blood fluid volume of the patient during the blood fluid removal session; determining whether a ratio of the indicator of tissue fluid volume to indicator of blood fluid volume is outside of a predetermined range; and altering the rate of fluid removal during the blood fluid removal session if the ratio is determined to be outside of the predetermined range. A blood fluid removal system may be configured to carry out the method.
    Type: Application
    Filed: March 20, 2012
    Publication date: November 1, 2012
    Inventors: Martin Gerber, John Burnes, SuPing Lyu, VenKalesh R. Manda, Bryant Pudil
  • Publication number: 20120277604
    Abstract: A method includes monitoring an indicator of fluid volume of a patient via a sensor device, and setting an initial fluid volume removal prescription for a blood fluid removal session based on the monitored indicator of fluid volume. The method may further include transmitting data regarding the indicator of fluid volume from the implantable sensor device to fluid removal device. In some embodiments, the fluid removal device sets or calculated the initial fluid volume removal prescription based on the data received from the implantable sensor. The indicator of fluid volume may be an indicator of tissue fluid volume or an indicator of blood fluid volume.
    Type: Application
    Filed: March 20, 2012
    Publication date: November 1, 2012
    Inventors: Martin Gerber, John Burnes, SuPing Lyu, VenKatesh R. Manda, Byant Pudil
  • Publication number: 20120273415
    Abstract: Monitoring of the performance of a blood fluid removal medium of a blood fluid removal device includes monitoring of condition, such as fluid flow rate or concentration of blood waste product, downstream of the medium. Upstream monitoring of the condition may also be performed to enhance the ability to determine whether the blood fluid removal medium is performing within predetermined ranges.
    Type: Application
    Filed: March 20, 2012
    Publication date: November 1, 2012
    Inventors: Martin Gerber, SuPing Lyu, Bryant Pudil
  • Publication number: 20120277650
    Abstract: A method includes initiating a blood fluid removal session for a patient in need thereof; monitoring a cardiovascular parameter of the patient; determining whether the indicator of the cardiovascular state crosses a predetermined threshold; and altering a parameter of the blood fluid removal session if the indicator is determined have crossed the threshold.
    Type: Application
    Filed: March 20, 2012
    Publication date: November 1, 2012
    Inventors: Martin Gerber, John Burnes, SuPing Lyu, VenKatesh R. Manda, Bryant Pudil
  • Publication number: 20120273420
    Abstract: Methods include monitoring indicators of blood pH or blood electrolyte levels during a blood fluid removal session and adjusting concentrations of pH buffers or electrolytes in dialysate or replacement fluid used during the session based on the monitored indicators. Blood fluid removal systems may employ sensors that monitor blood pH or electrolyte levels to adjust the fluid parameters during a blood fluid removal session.
    Type: Application
    Filed: March 20, 2012
    Publication date: November 1, 2012
    Inventors: Martin Gerber, John Burnes, SuPing Lyu, VenKatesh R. Manda, Bryant Pudil
  • Publication number: 20120277722
    Abstract: Methods for monitoring patient parameters and blood fluid removal system parameters include identifying those system parameters that result in improved patient parameters or in worsened patient parameters. By comparing the patient's past responses to system parameters or changes in system parameters, a blood fluid removal system may be able to avoid future use of parameters that may harm the patient and may be able to learn which parameters are likely to be most effective in treating the patient in a blood fluid removal session.
    Type: Application
    Filed: March 20, 2012
    Publication date: November 1, 2012
    Inventors: Martin Gerber, John Burnes, SuPing Lyu, VenKatesh R. Manda, Bryant Pudil
  • Publication number: 20120277552
    Abstract: Methods include monitoring blood pH or electrolyte levels and setting initial fluid parameters, such as dialysate fluid parameters or replacement fluid parameters, for a blood fluid removal session based the monitored data. Blood fluid removal systems may employ sensors that monitor blood pH or electrolyte levels to adjust the fluid parameters during a blood fluid removal session.
    Type: Application
    Filed: March 20, 2012
    Publication date: November 1, 2012
    Inventors: Martin Gerber, SuPing Lyu, Bryant Pudil
  • Publication number: 20120263761
    Abstract: A pharmaceutical depot includes a biodegradable polymer having a glass transition temperature of 20 degrees centigrade or less and at least 25% wt solid particles suspended in the biodegradable polymer. The pharmaceutical depot also includes a post-operative pain relieving therapeutic agent.
    Type: Application
    Filed: October 27, 2011
    Publication date: October 18, 2012
    Applicant: Warsaw Orthopedic, Inc.
    Inventors: PHILLIP E. MCDONALD, Suping Lyu
  • Patent number: 8129477
    Abstract: Implantable medical devices and methods including blends of biodegradable polymers are disclosed herein. The polymer blends include a continuous phase in which the polymer chains are oriented along an axis. Such polymer blends can exhibit properties such as improved toughness that can be desirable for use in medical devices.
    Type: Grant
    Filed: August 3, 2009
    Date of Patent: March 6, 2012
    Assignee: Medtronic, Inc.
    Inventors: Jianbin Zhang, SuPing Lyu, James Louis Schley
  • Publication number: 20110066029
    Abstract: An insertable or implantable medical device includes an elongated member having a proximal end, a distal end, at least one conductive coil near the distal end, and electrical conductors which carry current from the coil towards the proximal end. The coil surrounds or is surrounded by a flexible magnetic polymeric composite.
    Type: Application
    Filed: September 11, 2009
    Publication date: March 17, 2011
    Applicant: Medtronic, Inc.
    Inventors: SuPing Lyu, Micheal R. Neidert, Christipher M. Hobot, James Louis Schley, Kenneth C. Gardeski
  • Publication number: 20090269390
    Abstract: Polymers, compositions, and medical devices useful for delivering (e.g., by local and/or sustained delivery) a haloacetate (e.g., dichoroacetate) to a tissue are disclosed herein. Such methods can be useful for treatment of diseases such as cancer.
    Type: Application
    Filed: April 23, 2009
    Publication date: October 29, 2009
    Applicant: Medtronic, Inc.
    Inventors: Lian Leon Luo, Michael Eric Benz, Christopher M. Hobot, SuPing Lyu
  • Patent number: 7596415
    Abstract: The present invention relates generally to medical devices; in particular and without limitation, to unique electrodes and/or electrical lead assemblies for stimulating cardiac tissue, muscle tissue, neurological tissue, brain tissue and/or organ tissue; to electrophysiology mapping and ablation catheters for monitoring and selectively altering physiologic conduction pathways; and, wherein said electrodes, lead assemblies and catheters optionally include fluid irrigation conduit(s) for providing therapeutic and/or performance enhancing materials to adjacent biological tissue, and wherein each said device is coupled to or incorporates nanostructure or materials therein. The present invention also provides methods for fabricating, deploying, and operating such medical devices.
    Type: Grant
    Filed: January 20, 2005
    Date of Patent: September 29, 2009
    Assignee: Medtronic, Inc.
    Inventors: Scott J. Brabec, Kenneth C. Gardeski, Suping Lyu, James A. Coles, Jr., Christopher M. Hobot
  • Publication number: 20090187236
    Abstract: A medical electrical electrode includes an elongated conductive coil located over a lead body, and a conductive polymer material in contact with the lead body and located between individual coils of the elongated conductive coil. In certain embodiments, the conductive polymer is a polymer (e.g., silicone) implanted with a conductive filler (e.g., carbon black). In certain embodiments, the conductive polymer material is generally isodiametric with an outer diameter of the individual coils of the elongated conductive coil. A medical electrical electrode is fabricated by sliding an elongated conductive coil over a length of a lead body, dispersing a conductive polymer on the helical coil, inserting a tubing over the elongated conductive coil, distributing the polymer material between individual turns of the elongated conductive coil, heating the tubing so the tubing shrinks around the elongated conductive coil, and removing the tubing.
    Type: Application
    Filed: March 30, 2009
    Publication date: July 23, 2009
    Applicant: Medtronic, Inc.
    Inventors: Mark T. Marshall, Teresa A. Whitman, Suping Lyu, Elizabeth K. Nagy, David S. Olson
  • Patent number: 7512447
    Abstract: A medical electrical electrode includes an elongated conductive coil located over a lead body, and a conductive polymer material in contact with the lead body and located between individual coils of the elongated conductive coil. In certain embodiments, the conductive polymer is a polymer (e.g., silicone) implanted with a conductive filler (e.g., carbon black). In certain embodiments, the conductive polymer material is generally isodiametric with an outer diameter of the individual coils of the elongated conductive coil. A medical electrical electrode is fabricated by sliding an elongated conductive coil over a length of a lead body, dispersing a conductive polymer on the helical coil, inserting a tubing over the elongated conductive coil, distributing the polymer material between individual turns of the elongated conductive coil, heating the tubing so the tubing shrinks around the elongated conductive coil, and removing the tubing.
    Type: Grant
    Filed: April 25, 2005
    Date of Patent: March 31, 2009
    Assignee: Medtronic, Inc.
    Inventors: Mark T. Marshall, Teresa A. Whitman, Suping Lyu, Elizabeth K. Nagy, David S. Olson
  • Publication number: 20080069856
    Abstract: A process for making an implantable material comprising a composite of a biocompatible polymer and a bioactive agent. The composite combines desirable mechanical properties of polymers and the bioactivity of tissue or one or more component of tissue. More particularly, but not exclusively, the invention relates to methods for the manufacture of implantable materials, devices and components via a powder molding process.
    Type: Application
    Filed: September 20, 2006
    Publication date: March 20, 2008
    Inventors: SuPing Lyu, Christopher M. Hobot, Sean M. Haddock, Brian Loy, Randall V. Sparer, K. Matthew Kinnane, Jeffrey M. Gross
  • Publication number: 20070276504
    Abstract: Polymer-coated medical devices having improved structural integrity and drug elution profile, and related methods. Treatment of a polymeric undercoat layer to reflow the undercoat polymer results in a substrate/coating interface with improved adhesion.
    Type: Application
    Filed: August 6, 2007
    Publication date: November 29, 2007
    Applicant: Medtronic, Inc.
    Inventors: Randall Sparer, Christopher Hobot, SuPing Lyu
  • Publication number: 20070249754
    Abstract: Methods of modifying polyurethanes using surface treated clay are disclosed herein. Such methods can be useful for controlling the surface concentration of one or more additives in the polyurethane, which can be useful for fabricating medical devices therefrom.
    Type: Application
    Filed: April 24, 2007
    Publication date: October 25, 2007
    Applicant: Medtronic, Inc.
    Inventors: SuPing Lyu, Thomas P. Grailer, James Louis Schley, Christopher M. Hobot, Christopher A. Deegan, Randall V. Sparer
  • Publication number: 20070048288
    Abstract: Cell delivery compositions including shear thinning polymers and their use in cell delivery are described. The cell delivery compositions include shear thinning polymers that confer higher viscosity when at rest and decreased viscosity when subject to shear stress when dissolved or suspended in a carrier liquid. These shear thinning properties can facilitate cell delivery. Shear thinning polymer solutions may be used to deliver cells to particular tissue sites in a subject.
    Type: Application
    Filed: August 30, 2005
    Publication date: March 1, 2007
    Inventors: SuPing Lyu, Brian Fernandes, Matthew Bergan
  • Publication number: 20060241734
    Abstract: A medical electrical electrode includes an elongated conductive coil located over a lead body, and a conductive polymer material in contact with the lead body and located between individual coils of the elongated conductive coil. In certain embodiments, the conductive polymer is a polymer (e.g., silicone) implanted with a conductive filler (e.g., carbon black). In certain embodiments, the conductive polymer material is generally isodiametric with an outer diameter of the individual coils of the elongated conductive coil. A medical electrical electrode is fabricated by sliding an elongated conductive coil over a length of a lead body, dispersing a conductive polymer on the helical coil, inserting a tubing over the elongated conductive coil, distributing the polymer material between individual turns of the elongated conductive coil, heating the tubing so the tubing shrinks around the elongated conductive coil, and removing the tubing.
    Type: Application
    Filed: April 25, 2005
    Publication date: October 26, 2006
    Inventors: Mark Marshall, Teresa Whitman, Suping Lyu, Elizabeth Nagy, David Olson