Abstract: The present invention relates to an article for use as part of a non-combustible aerosol provision system, the article comprising: a housing; an aerosol generating component; and an aerosol generating material transfer component, the aerosol generating component and the aerosol generating material transfer component being housed within the housing, wherein the aerosol generating component is urged against the aerosol generating material transfer component.

Abstract: An improved apparatus for storing a wide assortment of articles in the form of a modular rail system and corresponding attachments which can be quickly attached and detached from said modular rail system, as well as remaining secure when attached.

Abstract: According to at least one embodiment, a method, a computer system, and a computer program product for notifying emergency personnel is provided. The present invention may include continuously monitoring a dependent using one or more dependent devices wherein the continuous monitoring of the dependent comprises monitoring a location of the dependent or a presence of one or more abnormal conditions; and automatically initiating a dependent alert SOS call to emergency personnel using the dependent devices, wherein the automatically initiating the dependent alert SOS call to the one or more emergency personnel occurs upon receiving a guardian activated SOS signal from one or more guardian devices or upon the presence of the one or more abnormal conditions. Additionally, the present invention may include detecting whether one or more guardian devices initiated the guardian-activated SOS signal and detecting of the presence of the one or more abnormal conditions.

Abstract: A spool unloading device comprising: a spindle; a first bulk spool of material is mounted on the spindle, wherein the spindle is rotatably controlled to dispense the material; a series of pulleys for receiving the unspooled material such that a variable length of the material is stored within the device before exiting the device to an upstream equipment; and a drive mechanism for indexing the unspooled material exiting the spool unloading machine at a controlled rate.

Abstract: An implant in accordance with an embodiment of the present technology includes proximal and distal end portions spaced apart from one another along a longitudinal axis and configured to be deployed at first and second airways, respectively, of a bronchial tree, the second airway being of a greater generation than the first airway. The implant includes a wire extending along a wire path within a tubular region coaxially aligned with the longitudinal axis. The wire includes first and second legs alternatingly disposed along the wire path and extending distally and proximally, respectively, in a circumferential direction about the longitudinal axis. The implant is configured to transition from a low-profile delivery state to an expanded deployed state at a treatment location and to allow mucociliary clearance from immediately distal to the implant to immediately proximal to the implant while the in deployed at the treatment location.

Abstract: A truck bed storage system provides multiple different use configurations, including a cap, a rack, and a bed cover. Elements of the system are reconfigurable to assemble the different use configurations. The system is easily assembled, reconfigured, or disassembled. The system includes a modular frame which connects to the truck bed and is used in the rack and cap configurations. A bed cover is removably attached to the top of the frame in the cap configuration, and connects to the top of the bed in the bed cover configuration. Removable panels attach to the frame in the cap configuration.

Abstract: A consumable for use with an aerosol provision device includes a support and aerosol generating material. The aerosol generating material includes one or more or discrete portions of aerosol generating material and the discrete portions are supported on the support. At least one discrete portion has a detectable characteristic, and the detectable characteristic is indicative of at least one product characteristic of the discrete portion.

Abstract: Systems and methods are provided for operating molten carbonate fuel cells to produce increased amounts of H2 in the anode effluent while still maintaining operation of the cell within conventional operation boundaries, such as having a temperature differential between the cathode input flow and the cathode effluent of 35° C. or more, with the cathode effluent being hotter than the cathode input flow. This temperature differential between the cathode input flow and the cathode effluent while still producing excess hydrogen is achieved in part by a) passing an input flow containing hydrocarbons and/or reformable fuel into an external reformer, b) reforming 20 vol % or more of the hydrocarbons and/or reformable fuel in the external reformer prior to c) passing the partially reformed input flow into a fuel cell or fuel cell stack where additional reforming is performed in the anode(s) and/or in a reforming element in the fuel cell stack.

Abstract: The invention relates to compounds of Formula (I)-(III) and pharmaceutically acceptable salts thereof to their use in medicine; to compositions containing them; to processes for their preparation; and to intermediates used in such processes. The compounds the present invention may be useful in the treatment, prevention, suppression and amelioration diseases, disorders and conditions such as cancers.

Abstract: This invention relates to a truncated dysferlin nucleic acid and protein, vectors (e.g., adeno-associated virus vectors) comprising the nucleic acid and methods of using the same for delivery of dysferlin to a cell or a subject and treating dysferlinopathy.

Abstract: A control system for controlling a surgical robot system, the surgical robot system comprising a surgical robot, the surgical robot comprising a base, and an arm extending from the base to an attachment for an instrument, the arm comprising a plurality of joints whereby the configuration of the arm can be altered, the control system comprising: a main controller configured to: receive communications identifying inputs from an operator of the surgical robot; generate control signals for controlling the movement of the surgical robot arm based on the inputs; and send communications to the surgical robot identifying the control signals; and a safety device situated such that communications to and from the main controller pass through the safety device, the safety device being operable to selectively filter the communications to and/or from the main controller.

Abstract: The present invention relates to compounds of Formula (I): or pharmaceutically acceptable salts thereof, wherein Ring A, Ring B, R1—R16, n and p are defined herein. The novel nitrogen-linked benzisoxazole sulfonamide derivatives are useful in the treatment of abnormal cell growth, such as cancer, in patients. Additional embodiments relate to pharmaceutical compositions containing the compounds and to methods of using the compounds and compositions in the treatment of abnormal cell growth, such as cancer, in patients.

Abstract: A selector assembly incorporated into the frame of an airsoft handgun that is operable to configure the airsoft gun in a semi-automatic or full-automatic firing mode. The selector assembly is operable to adjust the position of a disconnector and a sear such that the engagement surfaces of the disconnector and sear are configured to interact with the hammer and firing assembly such that one or multiple rounds are propelled down the barrel for each trigger engagement.

Abstract: A system includes one or more control units configured to determine one or more fuel consumption models for an aircraft. A method includes determining, by one or more control units, one or more fuel consumption models for an aircraft. A non-transitory computer-readable storage medium comprising executable instructions that, in response to execution, cause one or more control units comprising a processor, to perform operations including determining one or more fuel consumption models for an aircraft.

Abstract: Agents, kits, and methods that utilize oxygenation to prevent and/or treat intestinal inflammation and/or infections caused by anaerobic microorganisms are provided. In several embodiments, the formulations are provided as a capsule within a capsule in order to separate an oxygen prodrug from a catalyst until the formulation is at a target site within the intestine. In several embodiments, the catalyst is provided in an excess of the oxygen prodrug. In several embodiments, the prodrug is within an inner capsule or coating and a biological material comprising a catalyst (e.g., yeast, spirulina, chlorella, etc.) surrounds the encapsulated prodrug and the biological material is within a capsule or coating. The agents, kits, and methods can be utilized to prevent and/or treat anaerobic bacterial infections of the intestinal lumen by enteric aerobization therapy.

Abstract: A comfortable insert comprises a retention structure sized for placement under the eyelids and along at least a portion of conjunctival sac of the upper and lower lids of the eye. The retention structure resists deflection when placed in the conjunctival sac of the eye and to guide the insert along the sac when the eye moves. The retention structure can be configured in many ways to provide the resistance to deflection and may comprise a hoop strength so as to urge the retention structure outward and inhibit movement of the retention structure toward the cornea. The insert may move rotationally with deflection along the conjunctival sac, and may comprise a retention structure having a cross sectional dimension sized to fit within folds of the conjunctiva. The insert may comprise a release mechanism and therapeutic agent to release therapeutic amounts of the therapeutic agent for an extended time.

Abstract: A system for matching a candidate and a financial sponsor is disclosed, including at least one user computing device in operable connection with a user network. An application server is in operable communication with the user network to host an application program for matching a candidate to a financial sponsor. The application program includes a user module enabling the generation of a candidate profile and a financial sponsor profile. A matching module matches a suitable candidate profile to a suitable financial sponsor profile, and a communication module enables the communication between a candidate and a financial sponsor.

Abstract: Agents, kits, and methods that utilize oxygenation to prevent and/or treat intestinal inflammation and/or infections caused by anaerobic microorganisms are provided. In several embodiments, the formulations are provided as a capsule within a capsule in order to separate an oxygen prodrug from a catalyst until the formulation is at a target site within the intestine. In several embodiments, the catalyst is provided in an excess of the oxygen prodrug. In several embodiments, the prodrug is within an inner capsule or coating and a biological material comprising a catalyst (e.g., yeast, spirulina, chlorella, etc.) surrounds the encapsulated prodrug and the biological material is within a capsule or coating. The agents, kits, and methods can be utilized to prevent and/or treat anaerobic bacterial infections of the intestinal lumen by enteric aerobization therapy.

Abstract: A quick-connector assembly for joining abutting flanged ends of two tubular members includes first and second connector portions joined by a rotatable hinge having a hinge pin coupling the first connector portion and the second connector portion so that the first and second connector portions encircle about abutting flanged ends of the tubular members when the first and second connector portions are in a closed position. Further, a stand having a bracket with at least one hole for accommodating the hinge pin is designed to at least partially support the weight of the connector assembly and the flanged ends of the tubular members.