Abstract: An in-cell touch panel device includes a first substrate, a plurality of color filters formed on an upper layer with respect to the first substrate and including a green color filter, a transmitter electrode formed on an upper layer with respect to the plurality of color filters, a receiver electrode formed on a lower layer with respect to the plurality of color filters, and a second substrate including a pixel electrode disposed on the second substrate. The transmitter electrode includes a gap portion formed in a portion overlapping the receiver electrode in a plan view and in a portion overlapping the green color filter in a plan view.

Abstract: A number of crystalline forms of N-(2-((6-(3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-methylureido)pyrimidin-4-yl)amino)-5-(4-ethylpiperazin-1-y1)phenyl)acrylamide are provided. These include a crystalline free base form, a crystalline monohydrochloride salt form, a crystalline dihydrochloride salt form, and a crystalline ethanesulfonate salt form. Methods of making and using crystalline compounds are also provided.

Abstract: A liquid crystal display device includes a first substrate, a second substrate, a vertical alignment liquid crystal layer, and a plurality of pixels. Each of the pixels includes a reflective region for performing display in a reflection mode. The first substrate includes a reflective electrode including a first region located within each of the plurality of pixels and a second region located between any two pixels, of the plurality of pixels, adjacent to each other, a transparent insulating layer provided to cover the reflective electrode, and a pixel electrode formed from a transparent conductive material and provided on the transparent insulating layer in each of the plurality of pixels. The second substrate includes a counter electrode provided to be opposite to the pixel electrode and the reflective electrode.

Abstract: A liquid crystal display panel includes pixels including a reflective region for display in a reflection mode and a transmissive region for display in a transmission mode. The liquid crystal display panel includes a liquid crystal layer including a nematic liquid crystal material having negative dielectric anisotropy and a chiral agent, a pixel electrode including a reflective conductive layer and a transparent conductive layer, a counter electrode, a light diffusing structure provided in common to the reflective region and the transmissive region, and a first vertical alignment film provided between the pixel electrode and the liquid crystal layer, and a second vertical alignment film provided between the counter electrode and the liquid crystal layer.

Abstract: A liquid crystal display device includes a first substrate, a second substrate, a vertical alignment liquid crystal layer, and a plurality of pixels. Each of the pixels includes a reflective region for performing display in a reflection mode. The first substrate includes a reflective electrode including a first region located within each of the plurality of pixels and a second region located between any two pixels, of the plurality of pixels, adjacent to each other, a transparent insulating layer provided to cover the reflective electrode, and a pixel electrode formed from a transparent conductive material and provided on the transparent insulating layer in each of the plurality of pixels. The second substrate includes a counter electrode.

Abstract: A liquid crystal display device includes a liquid crystal cell including a first substrate, a second substrate disposed on a viewer side to the first substrate, and a liquid crystal layer provided between the first substrate and the second substrate, and a first linear polarizer disposed on a viewer side to the liquid crystal cell, and has a plurality of pixels. Each of the pixels includes a reflective region where display is performed in a reflection mode. The liquid crystal display device does not include a ?/4 plate between the first linear polarizer and the liquid crystal layer. An in-plane retardation of the liquid crystal layer in the reflective region is configured to vary from approximately zero to approximately ?/4 depending on a voltage applied to the liquid crystal layer.

Abstract: A liquid crystal display device includes a first substrate, a second substrate, a vertical alignment liquid crystal layer, and a plurality of pixels. Each of the pixels includes a reflective region for performing display in a reflection mode. The first substrate includes a reflective electrode including a first region located within each of the plurality of pixels and a second region located between any two pixels, of the plurality of pixels, adjacent to each other, a transparent insulating layer provided to cover the reflective electrode, and a pixel electrode formed from a transparent conductive material and provided on the transparent insulating layer in each of the plurality of pixels. The second substrate includes a counter electrode.

Abstract: A liquid crystal display device includes a first substrate, a second substrate, a vertical alignment liquid crystal layer, and a plurality of pixels. Each of the pixels includes a reflective region for performing display in a reflection mode. The first substrate includes a reflective electrode including a first region located within each of the plurality of pixels and a second region located between any two pixels, of the plurality of pixels, adjacent to each other, a transparent insulating layer provided to cover the reflective electrode, and a pixel electrode formed from a transparent conductive material and provided on the transparent insulating layer in each of the plurality of pixels. The second substrate includes a counter electrode provided to be opposite to the pixel electrode and the reflective electrode.

Abstract: A liquid crystal display device includes an element substrate, a counter substrate, a liquid crystal layer sandwiched between the element substrate and the counter substrate, reflective electrodes placed on a surface of the element substrate that is located on the liquid crystal layer side, and a pair of alignment films each of which is placed on a corresponding one of a surface of the element substrate that is located on the liquid crystal layer side and a surface of the counter substrate that is located on the liquid crystal layer side. A liquid crystal composition contained in the liquid crystal layer contains a compound containing an alkoxy group. The alignment films contain a polymer including polyimide. The polyimide is derived from a polyamic acid and contains a side chain represented by Formula (1).

Abstract: The present invention found that, for example, inhibiting phosphorylation of a Ser residue in Regnase-1 is effective in treating and/or preventing diseases. The invention also found that, for example, inhibiting the binding of Regnase-1 with at least one factor selected from the group consisting of TBK1, IKKi, Act-1, IKK, and IRAK is effective in treating and/or preventing diseases.

Abstract: The present invention provides a composition for treating or preventing skin pigmentation, which contains fibroblasts as an active ingredient, wherein the fibroblasts are those fibroblasts which are less damaged than fibroblasts localized in a site where the skin pigmentation occurs, and the composition is characterized by being intended to be applied to a site where the pigmentation occurs or a dermis tissue around the site.

Abstract: Each pixel has a reflection region to produce a display in reflection mode. The first substrate includes: a pixel electrode for each pixel; and a first vertical alignment film. The second substrate includes: an opposite electrode opposite the pixel electrodes; and a second vertical alignment film. Of the first and second vertical alignment films, only the second vertical alignment film exerts an alignment-regulating force that determines a pretilt angle. Each pixel electrode includes a plurality of subpixel electrodes. The opposite electrode has an opening in an area corresponding to one of four corners of at least one of the plurality of subpixel electrodes. Liquid crystal molecules in a thickness-wise middle portion of the liquid crystal layer on the subpixel electrode are oriented toward the opening.

Abstract: Embodiments of the disclosure relate to tetrahydropyrazolopyrimidine compounds that act as antagonists or inhibitors for Toll-like receptors 7 and/or 8, and their use in pharmaceutical compositions effective for treatment of systemic lupus erythematosus (SLE) and lupus nephritis.

Abstract: Each pixel has a reflection region to produce a display in reflection mode. The first substrate includes: a pixel electrode for each pixel; and a first vertical alignment film. The second substrate includes: an opposite electrode opposite the pixel electrodes; and a second vertical alignment film. Of the first and second vertical alignment films, only the second vertical alignment film exerts an alignment-regulating force that determines a pretilt angle. Each pixel electrode includes a plurality of subpixel electrodes. The opposite electrode has an opening in an area corresponding to one of four corners of at least one of the plurality of subpixel electrodes. Liquid crystal molecules in a thickness-wise middle portion of the liquid crystal layer on the subpixel electrode are oriented toward the opening.

Abstract: The purpose of the present invention is to provide a molecule having a significant effect on the development of fibrosis and a substance capable of inhibiting fibrosis. This biomarker for fibrosis comprises RNA binding motif protein 7 (RBM7) and is useful as a biomarker for diagnosis of fibrosis. This fibrosis detection method comprising the step of detecting RBM7 in a biological sample from a subject preferably using an anti-RBM7 antibody is useful for diagnosis of fibrosis. This antifibrotic agent containing a substance which inhibits the expression of RBM7, preferably at least one nucleic acid drug selected from the group consisting of siRNAs, shRNAs, dsRNAs, miRNAs, and antisense nucleic acids against RBM7, is useful for treatment of fibrosis.

Abstract: A reflective-type liquid crystal display device includes: a first substrate including a light-reflective first electrode; a second substrate including a light-transmissive second electrode; a liquid crystal layer that is provided between the first electrode and the second electrode and takes a generally vertical alignment during black display; a polarizing layer provided on a viewer side of the second substrate; and a first retardation layer, a second retardation layer and a third retardation layer that are arranged in this order from a side of the polarizing layer, wherein 40°?|?3?2×?2+2×?1|?50°, 130°?|?3?2×?2+2×?1|?140°, 220°?|?3?2×?2+2×?1|?230° or 310°?|?3?2×?2+2×?1|?320° is satisfied, where ?1 denotes an angle formed between an absorption axis or a transmission axis of the polarizing layer and a slow axis of the first retardation layer, ?2 an angle formed between the absorption axis or the transmission axis of the polarizing layer and the slow axis of second retardation layer, and ?3 an angle formed betwe

Abstract: A liquid crystal display device includes a first substrate, a second substrate, a liquid crystal layer, and a plurality of pixels. Each of the pixels has a reflection region for performing display in a reflective mode. The first substrate includes a pixel electrode provided in each of the pixels and a reflection layer positioned opposite to the liquid crystal layer with respect to the pixel electrode. The reflection layer has a first region positioned in each of the pixels and a second region positioned between any two pixels adjacent to each other. Voltages of an identical polarity are applied to the liquid crystal layer for any two pixels adjacent to each other in a row direction, for any two pixels adjacent to each other in a column direction, or for all the pixels.

Abstract: A liquid crystal display panel includes pixels including a reflective region for display in a reflection mode and a transmissive region for display in a transmission mode. The liquid crystal display panel includes a liquid crystal layer including a nematic liquid crystal material having negative dielectric anisotropy and a chiral agent, a pixel electrode including a reflective conductive layer and a transparent conductive layer, a counter electrode, a light diffusing structure provided in common to the reflective region and the transmissive region, and a first vertical alignment film provided between the pixel electrode and the liquid crystal layer, and a second vertical alignment film provided between the counter electrode and the liquid crystal layer.

Abstract: A liquid crystal cell 10A according to the present invention includes: a pair of substrates 11 and 12 facing each other and having alignment films 11a and 12a formed on surfaces of the substrates, respectively, the surfaces facing each other; and a liquid crystal layer LC interposed between the substrates 11 and 12. The alignment films 11a and 12a contain a polymer for alignment films which has a hydrazide functional group represented by Chemical Formula (1).

Abstract: A display device includes a reflective electrode, a driving circuit section, a wiring, and a wiring expansion section. The reflective electrode is divided into split electrodes arranged with spaces, which transmit light, respectively provided thereamong and reflects light. The driving circuit section drives the reflective electrode. The wiring is connected to at least the split electrodes and the driving circuit section and composed of a conductive material having a light transmission property. The wiring expansion section is formed to expand in the wiring to overlap the space.