Patents by Inventor Takashi Tsuji

Takashi Tsuji has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210360976
    Abstract: To provide a mechanism that makes it possible to further improve the quality of the inhalation experience provided by a flavor component generation device, a flavor component generation control device for controlling a flavor component generation device includes an attachment section that has detachably attached thereto an element configured so as to consume stored contents and thereby contribute to the generation of a gas to which a flavor component is added. The flavor component generation control device includes a controller that controls processing in which, for each of a plurality of the elements that have been attached to the attachment section in the past, identification information for the element is associated with a parameter indicating the consumption amount of the contents consumed in generation of the gas to which the flavor component is added. The result is stored in a storage.
    Type: Application
    Filed: August 6, 2021
    Publication date: November 25, 2021
    Applicant: Japan Tobacco Inc.
    Inventors: Manabu TAKEUCHI, Takeshi AKAO, Yasuhiro ONO, Takashi FUJIKI, Takuma NAKANO, Masayuki TSUJI, Ryoji FUJITA, Kazutoshi SERITA, Hiroshi TEZUKA
  • Publication number: 20210361636
    Abstract: The present invention relates to a novel fused ring compound having urea structure that exhibits excellent NAMPT activating effect, and a method using the same for treating/preventing metabolic disorder, cardiovascular and kidney disease, mitochondrial disease, neurodegenerative disease, ocular disease, and muscle wasting disorder. The present invention provides a compound represented by following formula (I) or a pharmacologically acceptable salt: Formula (I) wherein A, B, R, R2 and R3 represent the same meanings as in the claims.
    Type: Application
    Filed: July 3, 2019
    Publication date: November 25, 2021
    Inventors: Tsuyoshi NAKAMURA, Mayuko AKIU, Takashi TSUJI, Jun TANAKA, Koji TERAYAMA, Mika YOKOYAMA, Anthony B. PINKERTON, Edward Hampton SESSIONS
  • Publication number: 20210360970
    Abstract: A mechanism capable of specifying the arrangement of a flavor component generating base material in a suction device includes a retention part having an internal space; a pressure sensor for detecting a pressure applied to the inner wall of the retention part; and a control unit for specifying the arrangement of a flavor component generation base material in the internal space of the retention part on the basis of the detection result from the pressure sensor.
    Type: Application
    Filed: August 10, 2021
    Publication date: November 25, 2021
    Applicant: Japan Tobacco Inc.
    Inventors: Manabu TAKEUCHI, Takeshi AKAO, Yasuhiro ONO, Takashi FUJIKI, Takuma NAKANO, Masayuki TSUJI, Ryoji FUJITA, Kazutoshi SERITA, Hiroshi TEZUKA
  • Publication number: 20210352928
    Abstract: Provided is an edible material having an exceptional sweetness-enhancing effect. This oxidized product of a palm-based oil and fat has a total content of ?-carotene and ?-carotene of 50 mass ppm or more and 2000 mass ppm or less, and a peroxide value of the oxidized product of 3 or more and 250 or less.
    Type: Application
    Filed: October 24, 2019
    Publication date: November 18, 2021
    Inventors: Shun MATSUZAWA, Masayoshi SAKAINO, Misaki TSUJI, Takahiro TOKUCHI, Takashi SANO
  • Publication number: 20210352927
    Abstract: Provided is an edible material having an exceptional sweetness-enhancing effect. This method for producing an oil and fat composition is characterized in comprising a step for adding a carotenoid to an edible oil and fat, and a step for decomposing the carotenoid in the edible oil and fat. The carotenoid is preferably one or more selected from the group consisting of ?-carotene, ?-carotene, retinol, lutein, canthaxanthin, ?-cryptoxanthin, bixin, norbixin, astaxanthin, zeaxanthin, fucoxanthin, violaxanthin, lycopene, crocin, crocetin, and capsanthin.
    Type: Application
    Filed: October 24, 2019
    Publication date: November 18, 2021
    Inventors: Shun MATSUZAWA, Masayoshi SAKAINO, Misaki TSUJI, Takahiro TOKUCHI, Takashi SANO
  • Publication number: 20210355087
    Abstract: The present invention relates to a compound or a pharmacologically acceptable salt thereof having excellent tissue non-specific alkaline phosphatase inhibitory activity. The present invention provides a compound represented by the following formula (I): wherein X1 represents a nitrogen atom or CR9, R1 represents a hydrogen atom, a C1-C6 alkyl group, or a C1-C6 alkoxy group, R2 represents a halogen atom, R3 represents a hydrogen atom or a halogen atom, R4 represents a hydrogen atom or a halogen atom, and R5 represents a C1-C3 alkylsulfonyl group, a substituted C1-C6 alkyl group, a substituted C1-C6 haloalkyl group, a substituted C1-C6 alkoxy group, or a substituted C1-C6 alkylamino group, or a pharmacologically acceptable salt thereof.
    Type: Application
    Filed: October 22, 2019
    Publication date: November 18, 2021
    Applicants: DAIICHI SANKYO COMPANY, LIMITED, SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE
    Inventors: Takashi Tsuji, Yasunobu Kurosaki, Koutaro Ishibashi, Anthony B. Pinkerton
  • Patent number: 11155525
    Abstract: The present invention relates to a novel azole derivative as an apelin receptor agonist and a method for treating cardiovascular disease, diabetic disease, renal disease, hypertension, and arteriosclerosis, etc., using the same. The present invention provides a compound represented by formula (I) or a pharmacologically acceptable salt thereof wherein X1 represents —N? or —CH?, X2 represents —CH? or —N?, R1 and R2 each represent a C1 to C6 alkoxy group or the like, R3 represents a heteroaryl group (the heteroaryl group is optionally substituted by a methyl group or the like) or the like, and R4 represents a C1 to C6 alkylthio group or a C2 to C6 alkenyl group (the C1 to C6 alkylthio group and the C2 to C6 alkenyl group are each optionally substituted by one carboxy group or the like) or the like.
    Type: Grant
    Filed: April 20, 2020
    Date of Patent: October 26, 2021
    Assignee: SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE
    Inventors: Takuya Ikeda, Yoshiyuki Kobayashi, Naoki Miyoshi, Osamu Suzuki, Takahiro Nagayama, Takashi Tsuji, Layton H. Smith, Anthony B. Pinkerton
  • Publication number: 20210324491
    Abstract: An electrical steel sheet with an insulating film having excellent chromium elution resistance, even in the case where the insulating film is baked by utilizing rapid heating, which improves productivity, and a method for manufacturing the steel sheet. The insulating film contains Fe, Cr, an organic resin, and an organic reducing agent on at least one surface of an electrical steel sheet. A ratio of the Fe content to the Cr content (Fe/Cr) is 0.010 to 0.6 in terms of molar ratio in the insulating film.
    Type: Application
    Filed: July 8, 2019
    Publication date: October 21, 2021
    Applicant: JFE STEEL CORPORATION
    Inventors: Chiyoko TADA, Nobuko NAKAGAWA, Takashi WADA, Shota TSUJI, Naoki MURAMATSU
  • Publication number: 20210282390
    Abstract: A perfusion lumen is connected to at least one perfusion blood vessel among a plurality of blood vessels that extends from a branch of a plurality of blood vessels protruding from a liver, the branch existing on a distal side viewed from the liver, to a further distal side viewed from the liver. The perfusion lumen is supplied with perfusate to perfuse the liver and maintain the condition of the liver. Among blood vessels that are not connected to the perfusion lumen, at least one conserved blood vessel is obstructed and conserved for anastomosis to a blood vessel of the living body. Accordingly, the perfusion state of the liver is maintained even during anastomosis to the blood vessels of the living body. This enables anastomosis to the blood vessels of the living body while maintaining the perfusion state of the liver.
    Type: Application
    Filed: July 31, 2017
    Publication date: September 16, 2021
    Inventors: Eiji KOBAYASHI, Takashi TSUJI, Jun ISHIKAWA, Syuhei YOSHIMOTO, Shinji TORAI
  • Publication number: 20210196861
    Abstract: The present invention provides a method for producing regenerated hair follicle primordium that allows production of regenerated hair follicle primordium more easily and in larger amounts compared to conventional production methods. A method for producing regenerated hair follicle primordium comprising a step of obtaining hair follicle primordium by culturing a first population of cells comprising epithelial cells and a second population of cells comprising mesenchymal cells while allowing them to be in contact is provided. The production method of the present invention is characterized in that at least either one of said first population of cells and said second population of cells has formed cell aggregates before said contact, and a culture support is not used when contacting the other population of cells with said cell aggregate.
    Type: Application
    Filed: May 31, 2019
    Publication date: July 1, 2021
    Applicants: ORGAN TECHNOLOGIES, INC., RIKEN
    Inventors: Takashi Tsuji, Yutaka Mori, Koh-ei Toyoshima
  • Publication number: 20210145713
    Abstract: The present invention is directed to a hair growth agent for external use comprising chiro-inositol, which is provided as an excellent hair growth agent.
    Type: Application
    Filed: January 26, 2021
    Publication date: May 20, 2021
    Applicant: KOBAYASHI PHARMACEUTICAL CO., LTD.
    Inventors: Kosuke TANAKA, Mihoko KAWASAKI, Hironori TOMI, Takashi TSUJI
  • Publication number: 20210102890
    Abstract: Provided are a hair observation method, a phase contrast microscope system, and a preparation. The hair observation method includes capturing an infrared image of the hair using an image sensor that is capable of detecting infrared light. A phase contrast microscope system includes: a stage having a sample placed thereon; an infrared light irradiation source for irradiating infrared light to the sample placed on the stage; an image sensor that is capable of detecting infrared light and configured to capture an infrared image of the sample; and a display apparatus configured to display the infrared image captured by the image sensor. The preparation includes a microscope glass and a plurality of hair pieces that are obtained by cutting one hair and arranged on the microscope glass in a manner parallel with one another from one end to another end in a cutting order.
    Type: Application
    Filed: April 18, 2018
    Publication date: April 8, 2021
    Inventors: Takashi TSUJI, Koh-ei TOYOSHIMA, Kazuto MIYAZAKI, Takashi SAOTOME
  • Patent number: 10933001
    Abstract: The present invention is directed to a hair growth agent for external use comprising chiro-inositol, which is provided as an excellent hair growth agent.
    Type: Grant
    Filed: April 27, 2017
    Date of Patent: March 2, 2021
    Assignee: KOBAYASHI PHARMACEUTICAL CO., LTD.
    Inventors: Kosuke Tanaka, Mihoko Kawasaki, Hironori Tomi, Takashi Tsuji
  • Patent number: 10886371
    Abstract: A silicon carbide semiconductor device, including a semiconductor substrate having first and second epitaxial layers. The second epitaxial layer is formed on a first main surface of the semiconductor substrate, and includes first and second semiconductor regions, selectively provided in a surface layer of the second epitaxial layer respectively in the active region and the border region, and a third semiconductor region. The semiconductor device further includes a trench penetrating the first and third semiconductor regions to reach the first epitaxial layer, a gate electrode provided in the trench via a gate insulating film, a first electrode electrically connected to the first and third semiconductor regions, and a second electrode provided at a second main surface of the semiconductor substrate. The second semiconductor region is separate from the first semiconductor region.
    Type: Grant
    Filed: April 19, 2019
    Date of Patent: January 5, 2021
    Assignee: FUJI ELECTRIC CO., LTD.
    Inventors: Takashi Tsuji, Akimasa Kinoshita
  • Publication number: 20200347022
    Abstract: The present invention relates to a novel azole derivative as an apelin receptor agonist and a method for treating cardiovascular disease, diabetic disease, renal disease, hypertension, and arteriosclerosis, etc., using the same. The present invention provides a compound represented by formula (I) or a pharmacologically acceptable salt thereof wherein X represents —N? or —CH?, X2 represents —CH? or —N?, R1 and R2 each represent a C1 to C6 alkoxy group or the like, R3 represents a heteroaryl group (the heteroaryl group is optionally substituted by a methyl group or the like) or the like, and R4 represents a C1 to C6 alkylthio group or a C2 to C6 alkenyl group (the C1 to C6 alkylthio group and the C2 to C6 alkenyl group are each optionally substituted by one carboxy group or the like) or the like.
    Type: Application
    Filed: April 20, 2020
    Publication date: November 5, 2020
    Inventors: Takuya IKEDA, Yoshiyuki KOBAYASHI, Naoki MIYOSHI, Osamu SUZUKI, Takahiro NAGAYAMA, Takashi TSUJI, Layton H. SMITH, Anthony B. PINKERTON
  • Publication number: 20200340915
    Abstract: Provided is a flow path that can easily feed a liquid in the flow path. A flow path (210) is the flow path (210) for feeding a liquid, at least a portion of the flow path (210) includes a first region having a plurality of first through-holes for maintaining a pressure in the flow path (210) at atmospheric pressure, and a second region having an affinity for the liquid, and the liquid is fed by a force caused by affinity for the second region.
    Type: Application
    Filed: January 18, 2019
    Publication date: October 29, 2020
    Applicant: NITTO DENKO CORPORATION
    Inventors: Kazuya MIWA, Ryota MASUDA, Makoto MIYAHARA, Takashi TSUJI, Mitsuhiko HORI
  • Patent number: 10765806
    Abstract: The present invention relates to a dosing mechanism including: a body (2); and a disposable portion (3) that is removably attached to the body (2), in which the disposable portion (3) includes: a pump that sucks a medicine from a medicine vessel and discharges the medicine to a patient; a suction-side tube (33) that extends from the pump toward the medicine vessel; a discharge-side tube (34) that extends from the pump toward the patient; and a connector (331, 341) that is located at a front end of at least one of the suction-side tube (33) and the discharge-side tube (34), and the body (2) includes a sensor (24) in a position corresponding to the suction-side tube (33) or the discharge-side tube (34) attached to the body (2).
    Type: Grant
    Filed: November 26, 2015
    Date of Patent: September 8, 2020
    Assignee: NITTO DENKO CORPORATION
    Inventors: Toru Mizutani, Takashi Tsuji, Hiroyuki Shinohara
  • Publication number: 20200188065
    Abstract: The present invention provides a dental implant device comprising a dental implant body and an implant fixture. Said implant fixture is characterized in that it comprises a portion to be fixed to said implant body and a portion to be fixed to a tooth adjacent to the transplantation site of said implant body in a subject, and is configured so that mechanical stimulation from the tooth adjacent to said transplantation site is transmissible to said implant body, and said implant device is characterized in that it is placed into the oral cavity of said subject so that said implant body is inserted at said transplantation site while said implant fixture is fixed to said implant body and the tooth adjacent to said transplantation site.
    Type: Application
    Filed: August 14, 2017
    Publication date: June 18, 2020
    Inventors: Takashi Tsuji, Masamitsu Oshima, Takuo Kuboki, Yoshiki Ando, Miho Ogawa
  • Patent number: 10626096
    Abstract: The present invention relates to a novel azole derivative as an apelin receptor agonist and a method for treating cardiovascular disease, diabetic disease, renal disease, hypertension, and arteriosclerosis, etc., using the same. The present invention provides a compound represented by formula (I) or a pharmacologically acceptable salt thereof wherein X1 represents —NH? or —CH?, X2 represents —CH? or —N?, R1 and R2 each represent a C1 to C6 alkoxy group or the like, R3 represents a heteroaryl group (the heteroaryl group is optionally substituted by a methyl group or the like) or the like, and R4 represents a C1 to C6 alkylthio group or a C2 to C6 alkenyl group (the C1 to C6 alkylthio group and the C2 to C6 alkenyl group are each optionally substituted by one carboxy group or the like) or the like.
    Type: Grant
    Filed: November 21, 2016
    Date of Patent: April 21, 2020
    Assignee: SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE
    Inventors: Takuya Ikeda, Yoshiyuki Kobayashi, Naoki Miyoshi, Osamu Suzuki, Takahiro Nagayama, Takashi Tsuji, Layton H. Smith, Anthony B. Pinkerton
  • Publication number: 20200006494
    Abstract: A silicon carbide semiconductor device, including a semiconductor substrate having first and second epitaxial layers. The second epitaxial layer is formed on a first main surface of the semiconductor substrate, and includes first and second semiconductor regions, selectively provided in a surface layer of the second epitaxial layer respectively in the active region and the border region, and a third semiconductor region. The semiconductor device further includes a trench penetrating the first and third semiconductor regions to reach the first epitaxial layer, a gate electrode provided in the trench via a gate insulating film, a first electrode electrically connected to the first and third semiconductor regions, and a second electrode provided at a second main surface of the semiconductor substrate. The second semiconductor region is separate from the first semiconductor region.
    Type: Application
    Filed: April 19, 2019
    Publication date: January 2, 2020
    Applicant: FUJI ELECTRIC CO., LTD.
    Inventors: Takashi TSUJI, Akimasa KINOSHITA