Abstract: The present invention discloses a freeze-dried preparation of chemiluminescent immune microspheres, and a preparation method and an application thereof. The preparation is composed of one or more spherical solid particles having the same composition, which are uniform, smooth, and highly stable. In the preparation process, a magnetic particle coating raw material, an acridinium ester marking raw material and a reagent storage agent are freeze-dried into microspheres, so that the freeze-dried preparation can be stored and transported at normal temperature; the microspheres prepared in the present invention can be sub-packaged conveniently into individual packs, which are hygienic, simple and clear, and convenient to get and use, thereby the safety and convenience of use are improved. The preparation provided by the present invention and the test kit prepared according to the present invention can be used for immunoassays that are not for a disease diagnoses or treatment purpose.

Abstract: A photonic structure is provided. The photonic structure includes a guiding region, a sensing region, and logic region. The guiding region has a first side and a second side opposite to the first side. The sensing region is disposed on the second side of the guiding region. The logic region is disposed on a side of the sensing region opposite to the guiding region. The guiding region, the sensing region, and the logic region are stacked along a vertical direction. A method for manufacturing the photonic structure is also provided.

Abstract: The present disclosure relates to novel RNAi agents designed to decrease the expression of ANGPTL8 in the liver, where the RNAi agents comprise delivery moieties conjugated to oligonucleotides optionally via a linker. The RNAi agents are useful in the treatment of diseases involving the regulation of ANGPTL8 expression.

Abstract: Embodiments of this application disclose a data processing method, which is used in a storage system. The method in embodiments of this application includes: A network interface card device receives a first access request of a first client, where the first access request carries an access address; the network interface card device detects whether the first access request has a conflict; and when the network interface card device detects that the first access request has a conflict, the network interface card device processes the conflict according to a processing policy. In embodiments of this application, when a conflict occurs, the network interface card device processes the conflict according to the processing policy. This avoids conflict management performed by a processor of a storage node, and saves a resource of the processor of the storage node.

Abstract: A method for arterial endothelial-enhanced functional T cell generation is provided. In the method, arterial endothelial cells enhance functional T cell generation by promoting the generation of hematopoietic progenitor cells with T-lineage bias. The first stage of T cell differentiation from human pluripotent stem cells (hPSCs) is optimized, and it is found that hPSC-derived autologous arterial endothelial cells increase the T cell potential of hematopoietic progenitor cells. Moreover, the T cells generated by arterial endothelial cell priming share similar function to that of human peripheral blood T cells. hPSC-derived CD19-CAR-T cells have been verified to have tumor-killing effects both in vivo and in vitro. The established hPSC-T differentiation system would provide a valuable resource for chimeric antigen receptor T cell (CAR-T) therapy.

Abstract: A method is provided that includes forming a cavity in a substrate. The cavity is formed to extend into the substrate from a first surface to a second surface. Sidewall spacers are formed on sidewalls of the substrate in the cavity. A semiconductor layer is formed on the second surface in the cavity of the substrate, and the semiconductor layer abuts the sidewall spacers in the cavity.

Abstract: Systems and methods automatically construct a realization of a model from an available set of alternative co-simulation components, where the realization meets one or more objectives, such as fidelity, execution speed, or memory usage, among others. The systems and methods may construct the realization model by setting up and solving a constrained optimization problem, which may select particular ones of the alternative co-simulation components to meet the objectives. The systems and methods may configure the realization, and execute the realized model through co-simulation. The systems and methods may employ and manage different execution engines and/or different solvers to run the realization of the model.

Abstract: A projector system includes a connector attachable to a lighting wiring base mounted on a ceiling surface of a room, a housing hanging from the connector, a communicator accommodated in the housing to obtain content to be projected onto a wall surface of the room, a projection unit accommodated in the housing to emit emission light to project a picture including the content onto the wall surface, a brightness sensor to sense a brightness of the room, and a corrector to control the emission light to correct an effect of a state of the wall surface on the projected picture in accordance with the brightness of the room.

Abstract: A semiconductor package includes a first substrate, a first layer structure, a second layer structure, a first antenna layer and an electronic component. The first antenna layer is formed on at least one of the first layer structure and the second layer structure, wherein the first antenna layer has an upper surface flush with a layer upper surface of the first layer structure or the second layer structure. The electronic component is disposed on a substrate lower surface of the first substrate and exposed from the first substrate. The first layer structure is formed between the first substrate and the second layer structure.

Abstract: Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising these compounds thereof, and use of these compounds in preparing drugs for inhibiting ROCK.

Abstract: A screen projection control method and an electronic device are provided. The screen projection control method includes detecting that a first electronic device and a second electronic device are connected with each other through a physical bus and confirming screen projection reference parameters based on the second electronic device and the physical bus; establishing a network link between the first electronic device and the second electronic device; obtaining multimedia data to-be-outputted by an output unit of the first electronic device; and transmitting the multimedia data to the second electronic device using the network link based on the screen projection reference parameters to allow the second electronic device to output the multimedia data.

Abstract: The disclosed computer-implemented method for producing adjustments to malware-detecting services may include (1) receiving, from a plurality of malware-detecting services executing on a plurality of client computing devices, a respective plurality of probability scores with corresponding model identifiers for an analyzed file and a plurality of respective identifiers describing the malware-detecting services, (2) building a training dataset from at least a portion of the received plurality of probability scores with corresponding model identifiers, and (3) performing a security action including (A) training, with the training dataset, a malware-detecting linear regression ensemble machine learning model that is specific to an identifier in the plurality of identifiers and (B) sending the trained linear regression ensemble machine learning model to one of the plurality of malware-detecting services executing on one of the client computing devices.

Abstract: A semiconductor device includes: at least one conductive feature disposed on a substrate; at least one dielectric layer overlying the substrate, a trench structure extending through the at least one dielectric layer; and a protection layer overlaying the trench structure.

Abstract: The disclosed computer-implemented method for dynamically augmenting machine learning models based on contextual factors associated with execution environments may include (1) generating a base machine learning model and a supplemental set of machine learning models, (2) determining at least one contextual factor associated with an execution environment of a machine learning system that is configured to make predictions regarding a set of input data using at least the base machine learning model, (3) selecting, based on the contextual factor, a continuation set of machine learning models from the supplemental set of machine learning models, and (4) directing the machine learning system to utilize both the base machine learning model and the continuation set of machine learning models when making predictions regarding the set of input data. Various other methods, systems, and computer-readable media are also disclosed.

Abstract: This disclosure provides a method and an apparatus for accessing a solid state disk (SSD). The method is applied to a storage node, the storage node includes a network interface card and an SSD, and the network interface card includes a memory. The network interface card receives a data write request sent by a client, where the data write request includes to-be-written data. The network interface card writes the to-be-written data to the memory of the network interface card, and the SSD obtains the to-be-written data from the memory of the network interface card and writes the to-be-written data to the SSD.

Abstract: An information processing method applied to an electronic device includes monitoring whether the target application is abnormal in response to a target application being started when the electronic device is in a target display mode, and in response to the target application being abnormal, switching a window of the target application from a first window display mode to a second window display mode such that the target application adapts to a target display mode. In the target display mode, the window of the target application is in the first window display mode indicated by the target display mode.

Abstract: A method for accessing a solid state disk and a storage device are provided. The storage device includes a network interface card, a memory, and a solid state disk, the network interface card receives to-be-written data and a write command, where the write command instructs to write the to-be-written data to the solid state disk; the network interface card writes the to-be-written data to the memory, and writes the write command to a submission queue of the solid state disk. Then, the network interface card notifies the solid state disk that there is a to-be-executed command in the submission queue of the solid state disk, where the to-be-executed command is the write command. The solid state disk obtains the to-be-written data from the memory and writes the to-be-written data to a medium of the solid state disk according to the write command.

Abstract: The disclosed computer-implemented method for malware detection using localized machine learning may include (i) generating a global score for a file using a global machine learning model, (ii) generating a localized score for the file using a localized machine learning model, (iii) determining that the file is malware using the global score, the localized score, and the local conviction threshold, and (iv) in response to determining that the file is malware, performing a security action to protect the computing device against malware. Various other methods, systems, and computer-readable media are also disclosed.