Abstract: An unmanned aerial vehicle (UAV) includes one or more processors individually or collectively configured to assess a location of the UAV, calculate a distance between the UAV and a flight-restricted region using the location of the UAV, assess whether the distance falls within a first distance threshold, and instruct the UAV to take a flight response measure selected from (1) a first flight response measure when the distance falls within the first distance threshold, and (2) a second flight response measure different from the first flight response measure when the distance falls outside the first distance threshold. The first flight response measure at least includes causing the UAV to descend or hover over a location. A rate at which the UAV descends is determined based on the location of the UAV.

Abstract: Neoantigens play a key role in the recognition of tumor cells by T cells. However, only a small proportion of neoantigens truly elicit T cell responses, and fewer clues exist as to which neoantigens are recognized by which T cell receptors (TCRs). To help determine the TCRs that interact with particular neoantigens, prediction models that predict TCR-binding specificities of neoantigens presented by different classes of major histocompatibility complex (MHCs) were developed. To confirm the applicability of the model to clinical settings, the prediction models were comprehensively validated by a series of analyses. The validated prediction models used a flexible transfer learning approach and differential learning schema to achieve highly accurate prediction of TCR binding specificity only using TCR sequence data, antigen sequence data, and MHC alleles.

Abstract: The present invention relates to an anti-4-1BB-anti-PD-L1 bispecific antibody, and a pharmaceutical composition and the use thereof. Specifically, the present invention relates to a bispecific antibody, which comprises a first protein functional region targeting 4-1BB and a second protein functional region targeting PD-L1 or PD-1, wherein the first protein functional region is a single-domain antibody against 4-1BB; and the second protein functional region is an anti-PD-L1 antibody, anti-PD-1 antibody, anti-CTLA-4 antibody or anti-HER-2 antibody, or an antigen-binding fragment thereof. The bispecific antibody has the function of blocking the binding of PD-L1 to a receptor PD-1, and binds to 4-1BB on an immune cell, such that the immune cell activity in a tumor microenvironment is activated and the effect of inhibiting tumor occurrence and development is improved more effectively.

Abstract: An aircraft control system and control method are disclosed. The system comprises a remote control apparatus with a first control rod and a flight controller associated with an aircraft. The first control rod is configured to move in a first movement direction to control a motion of the aircraft in a first motion direction when an external force is applied on the first control rod and after a withdrawal of the external force, the first control rod returns to a preset position. The remote control apparatus operates to generate one or more control signals corresponding to the withdrawal of the external force. The flight controller controls the aircraft to maintain a flight state based on said control signals and one or more state signals, which are generated based on a measurement of the flight state by a flight controller associated with the aircraft state measurement sensors carried by the aircraft.

Abstract: The present disclosure provides a product for preventing the deterioration of an adhesive layer and a method for manufacturing the product. The product comprises a first product housing, a second product housing, an adhesive layer, and a protective layer. The second product housing is opposite to the first product housing. A gap exists between the second product housing and the first product housing. The adhesive layer is disposed in the gap between the first product housing and the second product housing, adhering to the first product housing and the second product housing. The protective layer is disposed on the adhesive layer. The protective layer is disposed in the gap, covering the outer surface of the adhesive layer. The protective layer bonds and cross-links to the adhesive layer chemically.

Abstract: A dynamic link library loading method includes: when an identifier of a first dynamic link library is not in a list of loaded dynamic link libraries, allocating a handle to the first dynamic link library, and adding the identifier of the first dynamic link library and the handle allocated to the first dynamic link library to the list of the loaded dynamic link libraries; and when the first dynamic link library is an integrated dynamic link library, adding identifiers of one or more dynamic link libraries for integration and the handle allocated to the first dynamic link library to the list of loaded dynamic link libraries; and based on the handle allocated to the first dynamic link library, loading the first dynamic link library into a running memory of an electronic device.

Abstract: A site effect simulator, including a site effect simulator base plate, where counter-force pillars are vertically arranged at diagonals of the site effect simulator base plate, the counter-force walls are connected to counter-force pillars along two sides of the site effect simulator base plate, a plurality of single-layer soil boxes are arranged at the inner side of the site effect simulator base plate, wave-absorbing materials are arranged inside single-layer soil boxes, and sliding panels are arranged at an upper side and a lower side of each single-layer soil box. The present disclosure does not need to rely on other counter-force frames, has the characteristics of flexible use, and can be randomly placed, and the height can be adjusted randomly. With a servo hydraulic actuator with three directions and six degrees of freedom, seismic simulation tests can be realized independently.

Abstract: Control of a mobile device is transferred to and from an operator. In one aspect, a specification for triggering manual control of the mobile device is accessed. A location is identified within a geographic region that exhibits characteristics defined by the specification. The location is represented in a navigation map and is associated with an operator trigger. As the mobile device approaches the location, a request for manual control is provided to the operator based on the operator trigger, and manual control is initiated.

Abstract: The present disclosure relates to a shimming device. The shimming device may include at least one supporting component each of which is configured with a plurality of wire groove groups. Each of the plurality of wire groove groups may include a plurality of wire grooves. Each of the plurality of wire grooves may be in a closed shape. The closed shapes formed by the plurality of wire grooves may be nested. The shimming device may further include wires arranged in the wire grooves of the plurality of wire groove groups of the at least one supporting component.

Abstract: An asynchronous rolling mill with a super large diameter ratio comprises a rolling mill stand, a press-down device, a balancing device, an upper roll system, and an arc-shaped plate device. The arc-shaped plate device comprises an arc-shaped plate, the arc-shaped plate is arranged opposite to the upper roll, and the arc-shaped plate and the upper roll are cooperated to roll strips. The present disclosure also provides a method for rolling a strip using an asynchronous rolling mill with a super large diameter ratio. The asynchronous rolling mill can roll with super large diameter ratio and different speeds, and has a large angle to engage, thereby reducing the external friction force of a workpiece and improving strip forming quality.

Abstract: The present disclosure concerns a device for forming a multi-flavor composite structure filter rod in one step, including the following components: a tow transmission belt, a tow guiding horn-shaped mouth, a tow assembly paper collection groove, a cigarette lap adhesive applying device and multi-flavor adding devices. According to shapes and types of flavors, the multi-flavor adding devices are arranged in different sections to obtain one-step formation of the multi-flavor composite structure filter rods. The present disclosure also discloses a one-step method of forming the multi-flavor composite structure filter rod using the one-step forming device.

Abstract: An organic light-emitting material containing cyano-substituted ligand is disclosed. The organic light-emitting material is a metal complex containing a cyano-substituted ligand, which can be used as a light-emitting material in a light-emitting layer of an organic electroluminescent device. These new complexes can provide better device performance, e.g., narrower full width at half maximum, lower voltage values, and higher quantum efficiency, and the like. An electroluminescent device and a compound formulation containing the metal complex, and a compound capable of being used to prepare the metal complex are also disclosed.

Abstract: The present disclosure discloses an OLED package structure, a display panel and a method for preparing a package structure. The OLED package structure includes a substrate, an OLED disposed on the substrate, and a reinforcement hole disposed on at least one of the substrate and the OLED and extending along a side of the OLED towards the substrate; and an encapsulation layer covering the OLED, and at least a portion of the encapsulation layer extending into the reinforcement hole. Therefore, the reliability of the package structure can be increased, the adhesive strength of the package layer can be increased, peeling or package failure can be prevented, and the service life of the package structure can be improved.

Abstract: The present invention is a composition comprising an aqueous dispersion of polymer particles, polymeric organic crosslinked microspheres, and colloidal silica particles. The composition is useful in coating compositions for exterior applications to achieve a balance of excellent dirt pickup resistance and durability performance under accelerated testing conditions.

Abstract: Disclosed herein is a light-gauge, ultra-high strength weathering steel sheet with a composition, material properties, and surface characteristics that make it suitable for hot-stamping applications and making hot-stamped products. Also disclosed herein is a high friction rolled carbon alloy steel strip free of prior austenite grain boundary depressions and having a smear pattern. Still further disclosed herein is a high friction rolled carbon alloy steel strip that has been surface homogenized to provide a thin cast steel strip free of a smear pattern.

Abstract: A street lamp intelligent measurement and control device includes an MCU chip, and an electrical parameter measuring circuit, an NB-IoT communication circuit, a dimming circuit and a switching control circuit respectively connected to the MCU chip. The electrical parameter measuring circuit determines electrical parameter data and electrical energy data of a street lamp load, and transmits the electrical parameter data and the electrical energy data to the MCU chip. The MCU chip actively uploads the electrical parameter data and/or the electrical energy data to a remote control center according to a preset time interval, receives a controlling instruction from the remote control center, and sends out a switching signal and/or a dimming signal according to the controlling instruction. The switching control circuit controls an on-off of the street lamp load according to the switching signal sent by the MCU chip.

Abstract: A unique polyol compound formed by a reaction between a carbonate compound represented by Formula (I) and a polyamine compound is provided. A polyurethane-based adhesive composition comprising the polyol compound can produce an adhesive layer exhibiting superior bond strength and heat seal strength which will not be substantially deteriorated by the change in the weight ratio between isocyanate component and polyol component. Methods for preparing the polyol compound and for preparing the adhesive composition, as well as a laminate article prepared with said adhesive composition are also provided.

Abstract: The disclosure relates to a trunk floor mounting structure for a vehicle, and a vehicle. The trunk floor mounting structure is configured to be arrangeable in a boot of the vehicle, and includes: a floor including a front floor and a rear floor reversibly fixed to the front floor; and a suspension mechanism including a stop member and a limiting member cooperating with each other, the stop member having a fixed end fixed to a lower surface of the rear floor and a movable end capable of extending to a lower surface of the front floor, and the limiting member being configured to be arrangeable on at least one of a left side wall and a right side wall of the boot, wherein when the rear floor is flipped by a predetermined obtuse angle relative to the front floor from an initial position, the movable end abuts against the limiting member such that the rear floor is suspended in a suspended position.

Abstract: A chain saw includes a housing, a motor, a chain saw bar assembly, a tensioning assembly set on the housing, and an adjustment assembly set on the side cover corresponding to the tensioning assembly. The chain saw bar assembly is detachably connected to the first housing through the combination of the tensioning assembly and the elastic components, the adjustment assembly is movably connected with the tensioning assembly, and the adjustment assembly can adjust the relative position of the tensioning assembly and the guide shaft, to tension the chain set on the circumferential direction of the guide bar and tightly lock the chain saw bar assembly between the first housing and the side cover.

Abstract: A waterproof partition adapted to a button includes a waterproof film and a waterproof foam formed on a surface of the waterproof film and covering a periphery of the waterproof film. The waterproof foam is formed with an opening for providing a moving passage for pressing the button. The waterproof film has elasticity, and the waterproof film is annular.