Abstract: Described is a method for instilling the haptic dimension of texture to virtual and holographic objects using mid-air ultrasonic technology. A set of features is extracted from imported images using their associated displacement maps. Textural qualities such as the micro and macro roughness are then computed and fed to a haptic mapping function together with information about the dynamic motion of the user's hands during holographic touch. Mid-air haptic textures are then synthesized and projected onto the user's bare hands. Further, mid-air haptic technology enables tactile exploration of virtual objects in digital environments. When a user's prior and current expectations and rendered tactile texture differ, user immersion can break. A study aims at mitigating this by integrating user expectations into the rendering algorithm of mid-air haptic textures and establishes a relationship between visual and mid-air haptic roughness.

Abstract: A system providing various improved perceptions techniques for haptic feedback above interactive surfaces that require no contact with either tools, attachments or the surface itself is described. A range of receptors in a perceiving member which is part of the human body is identified to create substantially uniformly perceivable feedback. A vibration frequency that is in the range of the receptors in the perceiving member is chosen and dynamically altered to create substantially uniformly perceivable feedback throughout the receiving member.

Abstract: According to an aspect, an inflatable penile prosthesis includes a fluid reservoir configured to hold fluid, an inflatable member, and a pump assembly configured to transfer the fluid between the fluid reservoir and the inflatable member. The pump assembly includes a valve body, a pump bulb, and a deflation mode actuator. The valve body includes a bi-directional valve configured to move from an inflation position to a deflation position in response to an activation of the deflation mode actuator. The bi-directional valve in the inflation position is configured to open a fluid passageway in the valve body to transfer fluid from the pump bulb to the inflatable member. The bi-directional valve in the deflation position is configured to open a fluid passageway in the valve body to transfer fluid from the inflatable member to the fluid reservoir that bypasses the pump bulb.

Abstract: Systems and methods are disclosed for generating for display digital content (e.g., an advertisement, a feed item, or some other information) together with digital components (e.g., branding data for the application or the publisher of the application). When the server receives, from a user device, a digital content request, the server can determine whether the digital content request was transmitted in response to an application state being changed to an active focus. Based on determining that the digital content request is being sent in response to an application state being changed to an active focus, the server generates a response that includes digital content and one or more digital components (e.g., branding data), and transmits that response to the user device. When the user device receives the response, the user device generates for display the digital components and the digital content.

Abstract: A method and system for initiating message listening and routing message content to authorized user devices is disclosed. For a second user device to receive notifications regarding records of a first user, the second user device provides information identifying the first user to a notification service. The notification service verifies the identifying information. The notification service initiates one or more listeners to listen for messages flowing over a messaging bus that are relating to the first user. Once a message is identified, at least a portion of the message is used to generate a notification that may be sent to the second user device.

Abstract: The present invention concerns a method and apparatus for the modulation of an acoustic field for providing tactile sensations. A method of creating haptic feedback using ultrasound is provided. The method comprises the steps of generating a plurality of ultrasound waves with a common focal point using a phased array of ultrasound transducers, the common focal point being a haptic feedback point, and modulating the generation of the ultrasound waves using a waveform selected to produce little or no audible sound at the haptic feedback point.

Abstract: A garment production system, comprising a virtual development environment configured to receive and store in a database thereof body information relating to a user, establish measurements for the user based on the body information, display, on a display device connected to the virtual development environment, a virtual representation of the user using the established measurements, customize one or more garments for the user based on the established measurements, display, on the display device, a virtual representation of the one or more customized garments on the virtual representation of the user, receive and store in the database personalization information from the user regarding the one or more customized garments, and alter the one or more customized garments and the virtual representation thereof based on the received personalization information for manufacture thereof.

Abstract: The present application relates methods for treating a depressive symptom comprising administering an effective amount of a ? opioid receptor agonist or a pharmaceutically acceptable salt thereof to a subject in need thereof. Non-limiting examples of such agonist include the compounds of Formulas I, II, III, and IV, as well as the compounds of Table A.

Abstract: This invention relates to combination therapies comprising an EZH2 inhibitor and a chemotherapeutic agent, and associated pharmaceutical compositions, methods of treatment, and pharmaceutical uses.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for presenting a first application's interface within a second application's interface. One of the methods includes receiving, by an active application executing on a user device that is not an application store, digital content referencing a second application not installed on the user device; obtaining application store data for the second application; providing, a user interface of the active application, the digital content with an application store user interface that includes (i) the application store data for the second application and (ii) an install element for triggering installation of the second application on the user device from within the active application; detecting user interaction with the install element; and in response to detecting the user interaction with the install element, triggering a download of the second application independent of launching an application for the application store.

Abstract: An automated data entry system comprising target database servers for storing target database(s), a processing server configured to execute a client-application and configured to store a plurality of data objects including a document schema and a target database schema corresponding to the target database(s), and a client terminal connected to the processing server, configured to: generate a first graphical interface for connection to a target database, and to execute a second graphical interface for connection to the client-application. The processing server may also receive an electronic data file representing an unprocessed document, to associate the unprocessed document with a document schema and extract a data variable based on the document schema, and to generate a database operation comprising the data variable configured according to a target database schema.

Abstract: A robotic vehicle management system for the control, optimization and distribution of robotic vehicles is presented in which vehicle operational data is recorded and used to model and optimize a vehicle's travel path. A process for receiving data from multiple vehicles is disclosed, wherein the recorded data is used in the optimization of control systems with regards to travel path, fuel savings, safety, and other considerations. The recorded data may be used to improve system operations or operations of individual vehicles. Methods and techniques are also provided for reading data from vehicle sensors, applying analysis techniques to this data, and uploading improved operational processes to one or more vehicles or to a fleet of vehicles. Adaptive controls, learning based controls, navigation system and other capabilities may be included for optimization and distribution by this discloses system and methods.

Abstract: Provided are compounds of Formula (I?) or (I) below, or pharmaceutically acceptable salts thereof, and methods for their use and production.

Abstract: A method in an intermediate server of initiating updates to a secondary database based on activity in a primary database includes: retrieving primary data from a primary server hosting the primary database; retrieving secondary data from a secondary server hosting the secondary database; storing a combined data set including the primary data and the secondary data; responsive to receiving a request from a client device, presenting a portion of the combined data set to the client device; receiving, from the client device, input data associated with the portion of the combined data set and updating the combined data set in the memory; determining whether to synchronize the updated combined data set with at least one of the primary server and the secondary server; and when the determination is affirmative, selecting a subset of the combined data set for transmission to at least one of the primary and secondary servers.

Abstract: According to an aspect, an implantable device for penile construction includes a penile implant having a distal portion and a proximal portion. The distal portion includes a shaft portion configured to be disposed in a neophallus. The proximal portion defines a first strut and a second strut, and the proximal portion is configured to be attached to a pelvis structure.

Abstract: The present invention provides compounds of formula (I), wherein: R1 is unsubstituted C1-C6 alkyl; La is substituted or unsubstituted C1-C6 alkyl linker, substituted or unsubstituted C3-C10 carbocycle, substituted or unsubstituted heterocycle comprising one or two 5- or 6-member rings and 1-4 heteroatoms selected from N, O and S, or substituted or unsubstituted heteroaryl comprising one or two 5- or 6-member rings and 1-4 heteroatoms selected from N, O and S; and R2 and R3 are each, independently, H, substituted or unsubstituted C1-C6 alkyl, or substituted or unsubstituted C6-C10aryl; or alternatively, R2 and R3, together with the nitrogen atom to which they are attached, form a substituted or unsubstituted heteroaryl comprising one or two 5- or 6-member rings and 1-4 heteroatoms selected from N, O and S or a substituted or unsubstituted heterocycle comprising one or two 5- or 6-member rings and 1-4 heteroatoms selected from N, O and S.

Abstract: A hand grip apparatus for receiving operator input includes a body having a proximal end and a distal interface end for coupling to an input apparatus. A first control lever is attached to the body and extends away from the proximal end and terminates in a finger grip for receiving one of the operator's fingers. A second control lever is attached to the body and extends away from the proximal end terminating in a thumb grip for receiving the operator's thumb. Movement of at least one of the control levers is operable to produce a first control signal representing the movement. An input control is included on the body between the grip ends and has an actuator surface angled towards the finger grip end and configured to produce a second control signal in response to actuation by one of the operator's fingers.

Abstract: According to an aspect, an implant includes an inflatable member and a pump assembly configured to facilitate a transfer of a fluid from the reservoir to the inflatable member. The inflatable member has a sidewall that defines a lumen and a porous structure disposed within the lumen.

Abstract: A hand grip apparatus for receiving operator input includes a body having a proximal end and a distal interface end for coupling to an input apparatus. A first control lever is attached to the body and extends away from the proximal end and terminates in a finger grip for receiving one of the operator's fingers. A second control lever is attached to the body and extends away from the proximal end terminating in a thumb grip for receiving the operator's thumb. Movement of at least one of the control levers is operable to produce a first control signal representing the movement. An input control is included on the body between the grip ends and has an actuator surface angled towards the finger grip end and configured to produce a second control signal in response to actuation by one of the operator's fingers.