Patents by Inventor Thomas J. Nelson

Thomas J. Nelson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9567422
    Abstract: The invention relates to enamine resins which are the reaction products of a) an acetoacetylated resin, and a C1-C20 alkyl amine or a mixture of C1-C20 alkyl amines. The acetoacetylated resin is the reaction product of a polyol having 4 or more hydroxyl groups; and at least one acetoacetate. The invention also relates to an acetoacetylated resin which is the reaction product of a polyol having 4 or more hydroxyl groups and at least one acetoacetate, where a portion of the hydroxyl groups of the polyol are replaced by acetoacetate groups and the remaining hydroxyl groups are replaced by a saturated monofunctional carboxylic acid ester, unsaturated monofunctional carboxylic acid ester, or a mixture thereof; as well as to enamine resins prepared from these acetoacetylated resins. The invention also relates to curable coating compositions containing such resins or a mixture of those resins, at least one metallic drier compound; and optionally one or more solvents.
    Type: Grant
    Filed: February 4, 2011
    Date of Patent: February 14, 2017
    Assignee: NDSU RESEARCH FOUNDATION
    Inventors: Dean C. Webster, Thomas J. Nelson, Xiao Pan
  • Publication number: 20160354898
    Abstract: A laterally-stretched netting comprising a patterned abrasive layer on a first major surface thereof, and methods of making.
    Type: Application
    Filed: May 26, 2016
    Publication date: December 8, 2016
    Inventors: Aaron K. Nienaber, Ronald W. Ausen, John M. Brandner, Thomas J. Nelson, Stephen M. Sanocki
  • Publication number: 20160289447
    Abstract: The invention provides structural biocomposites comprising cellulose-based bast natural fibers, glass fibers, or mixtures thereof, and polyurethanes. The polyurethanes are synthesized from the reaction of polyfunctional bio-based polyols with polyisocyanates. The resultant polyurethanes have higher moduli, hardness, and Tg compared to other bio- and petroleum-based polyols. Methods of making the structural biocomposites are also disclosed.
    Type: Application
    Filed: November 18, 2014
    Publication date: October 6, 2016
    Inventors: Dean C. WEBSTER, Thomas J. NELSON, Nassibeh HOSSEINI, Chad A. ULVEN
  • Publication number: 20160256427
    Abstract: The present disclosure describes novel PKC-? activators chosen from halogenated esters of unsaturated fatty acids derivatives thereof, including halogenated esters of both polyunsaturated and monunsaturated fatty acids and derivatives thereof. The disclosure further relates to compositions, kits, and methods for treatment using the halogenated esters.
    Type: Application
    Filed: October 20, 2014
    Publication date: September 8, 2016
    Inventors: Thomas J. Nelson, Daniel L. Alkon
  • Publication number: 20160060236
    Abstract: The present invention relates to methods of activate an isoform of protein kinase C (PKC) for the treatment of neurological diseases including Alzheimer's disease and stroke using cyclopropanated or epoxidized derivatives of mono- and polyunsaturated fatty acids. The present invention also relates to methods of reducing neurodegeneration using cyclopropanated or epoxidized derivatives of mono- and polyunsaturated fatty acids.
    Type: Application
    Filed: July 20, 2015
    Publication date: March 3, 2016
    Applicant: Blanchette Rockefeller Neurosciences Institute
    Inventors: Thomas J. NELSON, Daniel L. ALKON
  • Patent number: 9163032
    Abstract: The present disclosure relates to esters of 8-[2-(2-pentyl-cyclopropylmethyl)cyclopropyl]-octanoic acid (“DCPLA”). The disclosure further relates to compositions, kits, and methods for treatment using the esters.
    Type: Grant
    Filed: November 13, 2012
    Date of Patent: October 20, 2015
    Assignee: Blanchette Rockefeller Neurosciences Insitute
    Inventors: Daniel L. Alkon, Thomas J. Nelson
  • Patent number: 9119825
    Abstract: The present invention relates to methods of activate an isoform of protein kinase C (PKC) for the treatment of neurological diseases including Alzheimer's disease and stroke using cyclopropanated or epoxidized derivatives of mono- and polyunsaturated fatty acids. The present invention also relates to methods of reducing neurodegeneration using cyclopropanated or epoxidized derivatives of mono- and polyunsaturated fatty acids.
    Type: Grant
    Filed: February 21, 2012
    Date of Patent: September 1, 2015
    Assignee: Blanchette Rockefeller Neurosciences Institute
    Inventors: Thomas J. Nelson, Daniel L. Alkon
  • Publication number: 20140323456
    Abstract: The present disclosure relates to esters of 8-[2-(2-pentyl-cyclopropylmethyl)cyclopropyl]-octanoic acid (“DCPLA”). The disclosure further relates to compositions, kits, and methods for treatment using the esters.
    Type: Application
    Filed: November 13, 2012
    Publication date: October 30, 2014
    Inventors: Daniel L. Alkon, Thomas J. Nelson
  • Publication number: 20140315990
    Abstract: The present disclosure relates to PKC activators and combinations thereof. The disclosure further relates to compositions, kits, uses, and methods thereof.
    Type: Application
    Filed: November 13, 2012
    Publication date: October 23, 2014
    Inventors: Daniel L. Alkon, Thomas J. Nelson
  • Publication number: 20130261251
    Abstract: Alkyd resin compositions which comprise the monomer-grafting polymerization of a) an alkyd, which is an ester of a polyol having 4 or more hydroxyl groups and an unsaturated fatty acid, and b) an unsaturated monomer having a carbon-carbon double bond are disclosed. The alkyd may be a partially esterified polyol. Coating compositions of containing the alkyd resin compositions of the invention are also disclosed.
    Type: Application
    Filed: June 16, 2011
    Publication date: October 3, 2013
    Applicant: NDSU RESEARCH FOUNDATION
    Inventors: Dean C. Webster, Thomas J. Nelson
  • Publication number: 20130036939
    Abstract: The invention relates to enamine resins which are the reaction products of a) an acetoacetylated resin, and a C1-C20 alkyl amine or a mixture of C1-C20 alkyl amines. The acetoacetylated resin is the reaction product of a polyol having 4 or more hydroxyl groups; and at least one acetoacetate. The invention also relates to an acetoacetylated resin which is the reaction product of a polyol having 4 or more hydroxyl groups and at least one acetoacetate, where a portion of the hydroxyl groups of the polyol are replaced by acetoacetate groups and the remaining hydroxyl groups are replaced by a saturated monofunctional carboxylic acid ester, unsaturated monofunctional carboxylic acid ester, or a mixture thereof; as well as to enamine resins prepared from these acetoacetylated resins. The invention also relates to curable coating compositions containing such resins or a mixture of those resins, at least one metallic drier compound; and optionally one or more solvents.
    Type: Application
    Filed: February 4, 2011
    Publication date: February 14, 2013
    Inventors: Dean C. Webster, Thomas J. Nelson, Xiao Pan
  • Publication number: 20120149768
    Abstract: The present invention relates to methods of activate an isoform of protein kinase C (PKC) for the treatment of neurological diseases including Alzheimer's disease and stroke using cyclopropanated or epoxidized derivatives of mono- and polyunsaturated fatty acids. The present invention also relates to methods of reducing neurodegeneration using cyclopropanated or epoxidized derivatives of mono- and polyunsaturated fatty acids.
    Type: Application
    Filed: February 21, 2012
    Publication date: June 14, 2012
    Inventors: Thomas J. Nelson, Daniel L. Alkon
  • Patent number: 8163800
    Abstract: The present invention relates to methods of activate an isoform of protein kinase C (PKC) for the treatment of neurological diseases including Alzheimer's disease and stroke using cyclopropanated or epoxidized derivatives of mono- and polyunsaturated fatty acids. The present invention also relates to methods of reducing neurodegeneration using cyclopropanated or epoxidized derivatives of mono- and polyunsaturated fatty acids.
    Type: Grant
    Filed: July 28, 2009
    Date of Patent: April 24, 2012
    Assignee: Blanchette Rockefeller Neurosciences Institute
    Inventors: Thomas J. Nelson, Daniel L. Alkon
  • Patent number: 8006536
    Abstract: A mechanism for forming thin metallic skin enclosures from blanks. The apparatus includes a forming assembly including a plurality of die stations. The stations are stepped farther away from an axis in a direction of which blanks being processed are positioned at a plurality of die stations. Grippers spaced along the axis and away from the axis at distances substantially the same as are die stations are carried by the transfer assembly. An actuator is used to move the transfer assembly reciprocally in directions generally parallel to the axis between first and second axial positions. A ram is provided to move the transfer assembly between first and second stepped positions relative to the axis.
    Type: Grant
    Filed: April 11, 2007
    Date of Patent: August 30, 2011
    Assignee: Greatbatch Ltd.
    Inventors: Thomas J. Nelson, Matthew Klun
  • Patent number: 7977377
    Abstract: The invention provides for the use of carbonic anhydrase activators; protein kinase C activators and FGF-18 to treat depressive disorders. The invention also relates to improved animal models and methods for screening and identifying compounds the treatment of depressive disorders.
    Type: Grant
    Filed: May 24, 2007
    Date of Patent: July 12, 2011
    Assignee: Blanchette Rockefeller Neurosciences Institute
    Inventors: Miao-Kun Sun, Daniel L. Alkon, Thomas J. Nelson
  • Patent number: 7913713
    Abstract: A combination wet kit includes a single mounting bracket supporting an end dump/return manifold and a walking floor/side dump/low boy manifold, as well as a support bracket for the hydraulic fluid filter. A three-way valve is positioned between the end dump/return manifold and a walking floor/side dump/low boy manifold. The manifold unit attached to the tractor without requiring holes in the tractor frame. The manifolds and the preassembled nature of the manifold assembly greatly simplify and reduce costs for installation of the combination wet kit.
    Type: Grant
    Filed: December 26, 2006
    Date of Patent: March 29, 2011
    Assignee: Clutch and Transmission Service, Inc.
    Inventor: Thomas J. Nelson
  • Patent number: 7803400
    Abstract: This invention relates to a highly efficient artificial low-density lipoprotein (LDL) carrier system for the targeted delivery therapeutic agents across the blood-brain barrier (BBB). In particular, this invention relates to artificial LDL particles comprised of three lipid elements: phosphatidyl choline, fatty-acyl-cholesterol esters, and at least one apolipoprotein. The present invention further relates to compositions, methods and kits comprising artificial LDL particles for targeting drugs to and across the BBB for the prevention and treatment of brain diseases.
    Type: Grant
    Filed: May 24, 2007
    Date of Patent: September 28, 2010
    Assignee: Blanchette Rockefeller Neurosciences Institute
    Inventors: Thomas J. Nelson, Daniel L. Alkon, Alessandro Quattrone
  • Publication number: 20100022645
    Abstract: The present invention relates to methods of activate an isoform of protein kinase C (PKC) for the treatment of neurological diseases including Alzheimer's disease and stroke using cyclopropanated or epoxidized derivatives of mono- and polyunsaturated fatty acids. The present invention also relates to methods of reducing neurodegeneration using cyclopropanated or epoxidized derivatives of mono- and polyunsaturated fatty acids.
    Type: Application
    Filed: July 28, 2009
    Publication date: January 28, 2010
    Applicant: BLANCHETTE ROCKEFELLER NEUROSCIENCES INSTITUTE
    Inventors: Thomas J. Nelson, Daniel L. Alkon
  • Patent number: 7614197
    Abstract: A disengageable connector for interconnecting panels includes a longitudinally extending connector body. The connector body including a base and a projection extending from the base. The base includes a top surface and a bottom surface, and at least one footing member extending downwardly from the bottom surface of the base. The footing member is shaped and dimensioned to compress the upper surface of a resilient pad positioned beneath the connector and the panels. The connector is used in conjunction with an interlocking flooring system. The interlocking flooring system includes a plurality of flooring panels, each flooring panel including a plurality of edges. A first connecting member is provided for connecting adjacent flooring panels and a second connecting member is provided for connecting adjacent flooring panels. The first connecting member is the same as the connector described above and is different from the second connecting member.
    Type: Grant
    Filed: November 14, 2003
    Date of Patent: November 10, 2009
    Assignee: Premark RWP Holdings, Inc.
    Inventor: Thomas J. Nelson
  • Publication number: 20090004443
    Abstract: A chair mat includes a first decorative layer, the first decorative layer being composed of melamine-formaldehyde impregnated decorative sheet. The chair mat also includes a central core layer including a top first surface and a bottom second surface, the central core layer being composed of at least one resin impregnated sheet. The first decorative layer is coupled to the top first surface of the central core layer. The chair mat also includes a second decorative layer coupled to the bottom second surface of the central core layer, the second decorative layer being composed of a melamine-formaldehyde impregnated decorative sheet.
    Type: Application
    Filed: June 30, 2008
    Publication date: January 1, 2009
    Inventor: Thomas J. Nelson