Patents by Inventor Ting Zhang
Ting Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10047413Abstract: A method for smelting magnesium quickly and continuously includes: preparing dolomite or magnesite with reductants and fluorite at a predetermined ratio, uniformly mixing the prepared ingredients to obtain pellets, and calcining the obtained pellets in an argon or nitrogen atmosphere; continuously feeding the high-temperature calcined pellets (without being cooled) under argon protection into a reduction furnace, and performing a high-temperature reduction reaction in a flowing argon atmosphere to obtain high-temperature magnesium steam; and enabling the high-temperature magnesium steam to be carried out of the high-temperature reduction furnace by an argon flow, and performing condensation to obtain metal magnesium. The present invention eliminates a vacuum system and a vacuum reduction tank, so that quick and continuous production of the metal magnesium is realized, the reduction time is shortened to 90 min or less, and the recovery rate of magnesium is increased to 88% or more.Type: GrantFiled: August 26, 2014Date of Patent: August 14, 2018Assignee: Northeastern UniversityInventors: Ting'an Zhang, Zhihe Dou, Zimu Zhang, Yan Liu, Guozhi Lv, Jicheng He
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Publication number: 20180153894Abstract: The present invention provides novel compounds of Formula (I), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, isotopically labeled derivatives, prodrugs, and compositions thereof. Also provided are methods and kits involving the inventive compounds or compositions for treating or preventing proliferative diseases (e.g., cancers (e.g., lung cancer, breast cancer, leukemia, lymphoma, melanoma, multiple myeloma, Ewing's sarcoma, osteosarcoma, brain cancer, neuroblastoma), benign neoplasms, angiogenesis, inflammatory diseases, autoinflammatory diseases, and autoimmune diseases) in a subject. Treatment of a subject with a proliferative disease using a compound or composition of the invention may inhibit the aberrant activity of a kinase (e.g. a protein kinase (e.g. a cyclin-dependent kinase (CDK) (e.g. CDK7, CDK12, or CDK13) or a lipid kinase such as a phosphatidylinositol-5-phosphate 4-kinase (PIP4K) (e.g.Type: ApplicationFiled: June 24, 2016Publication date: June 7, 2018Applicant: Dana-Farber Cancer Institute, Inc.Inventors: Nathanael S. Gray, Ting Zhang
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Publication number: 20180139280Abstract: Apparatuses and methods are disclosed for cluster switching. An exemplary method may include synchronizing original data on a first cluster to a second cluster after starting to switch clusters. A priority of the original data on the second cluster is set to a lower priority. The method may also include responding to a write operation request on the second cluster in the period of synchronizing the original data on the first cluster to the second cluster. A priority of new data corresponding to the write operation request is set to a higher priority. A version of data with a higher priority can overwrite another version of data. The method may further include responding to the write operation request on the second cluster after synchronizing the original data on the first cluster to the second cluster.Type: ApplicationFiled: January 12, 2018Publication date: May 17, 2018Inventors: Ting ZHANG, Zhongyu ZOU, Wenzhao LI, Ming YANG, Jinbo WU
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Patent number: 9969724Abstract: In its many embodiments, the present invention provides a novel class of benzamide compounds represented by Formula (I) or pharmaceutically acceptable salts or solvates thereof, or pharmaceutical compositions comprising one or more said compounds or pharmaceutically acceptable salts or solvates thereof, and methods for using said compounds or pharmaceutically acceptable salts or solvates thereof for treating or preventing a thromboses, embolisms, hypercoagulability or fibrotic changes.Type: GrantFiled: April 10, 2015Date of Patent: May 15, 2018Assignees: Merck Sharp & Dohme Corp., Mochida Pharmaceutical Co., Ltd.Inventors: Isao Sakurada, Tomokazu Hirabayashi, Yoshitaka Maeda, Hiroshi Nagasue, Takashi Mizuno, Jiayi Xu, Ting Zhang, Cameron Smith, Dann Parker
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Publication number: 20180073917Abstract: The invention discloses a flexible conductive diaphragm comprising at least one conductive film, and the conductive film comprises a flexible support layer (1), a flexible sensitive layer (2) overlapped on the flexible support layer (1), a flexible conductive layer (3) overlapped on the flexible sensitive layer (2), and an electrode (4) electrically connected with the flexible conductive layer (3). The invention further discloses a method for preparing the flexible conductive diaphragm, and a flexible vibration sensor based on the flexible conductive diaphragm. With the combination of the techniques such as the flexible material, the nano-material and the arrayed micro-structure, the flexible vibration sensor of the present invention has the characteristics of high sensitivity, low preparation cost, light weight, small thickness, small size, and being foldable and flexible, and can be applied in wearable or adherable electronic devices.Type: ApplicationFiled: August 13, 2015Publication date: March 15, 2018Inventors: Ting Zhang, Yang Gu
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Patent number: 9914727Abstract: The present invention provides compounds of Formula (I) and pharmaceutical compositions comprising compounds of Formula I, and methods for using compounds of Formula I for treating or preventing thromboses, embolisms, hypercoaguability or fibrotic changes.Type: GrantFiled: December 16, 2013Date of Patent: March 13, 2018Assignees: Merck Sharp & Dohme Corp., Mochida Pharmaceutical Co., Ltd.Inventors: Cameron James Smith, John Qiang Tan, Ting Zhang, James Balkovec, William John Greenlee, Liangqin Guo, Yi-Heng Chen, Yili Chen, Samuel Chackalamannil, Tomokazu Hirabayashi, Mika Sekioka
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Publication number: 20180030036Abstract: The present invention provides a compound of Formula I, and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing unstable angina, refractory angina, myocardial infarction, transient ischemic attacks, atrial fibrillation, thrombotic stroke, embolic stroke, deep vein thrombosis, disseminated intravascular coagulation, ocular build up of fibrin, and reocclusion or restenosis of recanalized vessels. The compounds are selective Factor IXa inhibitors.Type: ApplicationFiled: December 7, 2015Publication date: February 1, 2018Applicants: MERCK SHARP & DOHME CORP., MOCHIDA PHARMACEUTICAL CO., LTDInventors: Ting Zhang, Yi-Heng Chen, Liangqin Guo, Alan Hruza, Tianying Jian, Bing Li, Dongfang Meng, Dann L. Parker, Edward C. Sherer, Harold B. Wood, Isao Sakurada
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Publication number: 20180022747Abstract: The present invention provides a compound of Formula I and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing unstable angina, refractory angina, myocardial infarction, transient ischemic attacks, atrial fibrillation, thrombotic stroke, embolic stroke, deep vein thrombosis, disseminated intravascular coagulation, ocular build up of fibrin, and reocclusion or restenosis of recanalized vessels. The compounds are selective Factor IXa inhibitors.Type: ApplicationFiled: February 12, 2016Publication date: January 25, 2018Applicant: Merck Sharp & Dohme Corp.Inventors: Dongfang Meng, Hong Li, Meng Yang, Manuel de Lera Ruiz, Sunita V. Dewnani, Tianying Jian, Dann L. Parker, Jr., Ting Zhang, Louis-Charles Campeau, Harold B. Wood, Jiayi Xu, Richard Berger, Jane Yang Wu, Robert K. Orr, Shawn P. Walsh, Bart Harper
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Patent number: 9816882Abstract: The invention provides a piezoresistive electronic skin, a preparation method and a use thereof. The piezoresistive electronic skin uses carbon nanotube film as the conductive layer and uses materials provided with micro-nano patterns, such as polydimethylsiloxane, polyethylene terephthalate, polyvinyl alcohol, polyvinyl formal, polyethylene, and so on, as the substrate, enabling the substrate has advantages of high flexibility and being pliable, and it needs low operating voltage and little power consumption, but has high sensitivity and short response time. More importantly, the invention uses the patterned flexible substrate as the basis, greatly improving the sensitivity of electronic skin reacting to tiny applied force from outside. The invention also provides a capacitive electronic skin and a preparation method thereof. Further, the invention also provides a use of the piezoresistive electronic skin or the capacitive electronic skin on speech recognition, pulse detection, medical robot, etc.Type: GrantFiled: January 28, 2014Date of Patent: November 14, 2017Assignee: SUZHOU INSTITUTE OF NANO-TECH AND NANO-BIONICS (SINANO), CHINESE ACADEMY OF SCIENCESInventors: Ting Zhang, Xuewen Wang, Zuoping Xiong, Yang Gu, Wen Gu
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Patent number: 9808445Abstract: In its many embodiments, the present invention provides a novel class of benzamide compounds represented by Formula (I) or pharmaceutically acceptable salts or solvates thereof, or pharmaceutical compositions comprising one or more said compounds or pharmaceutically acceptable salts or solvates thereof, and methods for using said compounds or pharmaceutically acceptable salts or solvates thereof for treating or preventing a thromboses, embolisms, hypercoagulability or fibrotic changes.Type: GrantFiled: April 10, 2015Date of Patent: November 7, 2017Assignees: Merck Sharp & Dohme Corp., Mochida Pharmaceutical Co., Ltd.Inventors: Isao Sakurada, Tomokazu Hirabayashi, Yoshitaka Maeda, Hiroshi Nagasue, Takashi Mizuno, Jiayi Xu, Ting Zhang, Cameron Smith, Dann Parker
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Publication number: 20170278392Abstract: A computer-implemented method includes receiving a data stream, the data stream including one or more driving factors. The computer-implemented method further includes comparing the one or more driving factors to one or more known driving factors to identify a driving scenario. The computer-implemented method further includes monitoring the driving scenario for a risk. Monitoring the driving scenario for a risk further includes detecting the risk. The computer-implemented method further includes generating an intervention, wherein the intervention is generated based on detecting the risk for the driving scenario. A corresponding computer system and computer program product are also disclosed.Type: ApplicationFiled: May 15, 2017Publication date: September 28, 2017Inventors: Ci-Wei Lan, Wen Zhu Liu, Dong Ni, Yiping Qu, Yu Wei Sun, Li Yue, Jie Xu, Ting Ting Zhang
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Patent number: 9708308Abstract: The present invention provides a compound of Formula (I) wherein R1 is H or C1-6 alkyl, R2, is H or C1-6 alkyl or CH2OH, R3 is H or C1-6 alkyl, and R4 is H or C1-6 alkyl, provided that when R1, R2, and R3 are H, R4 is C1-6 alkyl, and when R1, R2, and R4 are H, then R3 is C1-6 alkyl, and when R1, R3, and R4 are H, R2 is C1-6 alkyl or —CH2OH, and when R2, R3, and R4 are H, then R1 is C1-6 alkyl; A is 1) a 9-10 membered bicyclic heterocycle having 1-3 heteroatoms independently selected from N, S and O, which 9-10 membered bicyclic heterocycle is unsubstituted or substituted with R5 and unsubstituted or substituted with R6 and unsubstituted or substituted with NH2, or 2) a 6-9 membered monocyclic or bicyclic carbocyclic ring system unsubstituted or substituted with R5, unsubstituted or substituted with R6, and unsubstituted or substituted with —CH2NH2; and B is 1) a 5- or 6-membered monocyclic heterocycle having 1 or 2 heteroatoms independently selected from N, S or O, which is unsubstituted or substitutType: GrantFiled: December 16, 2013Date of Patent: July 18, 2017Assignees: Merck Sharp Dohme Corp., Mochida Pharmacuetical Co., Ltd.Inventors: Cameron James Smith, John Qiang Tan, Ting Zhang, James Balkovec, William John Greenlee, Liangqin Guo, Yi-Heng Chen, Yili Chen, Jiayi Xu, Samuel Chackalamannil, Tomokazu Hirabayashi, Hiroshi Nagasue, Kouki Ogawa
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Patent number: 9701340Abstract: A computer-implemented method includes receiving a data stream, the data stream including one or more driving factors. The computer-implemented method further includes comparing the one or more driving factors to one or more known driving factors to identify a driving scenario. The computer-implemented method further includes monitoring the driving scenario for a risk. Monitoring the driving scenario for a risk further includes detecting the risk. The computer-implemented method further includes generating an intervention, wherein the intervention is generated based on detecting the risk for the driving scenario. A corresponding computer system and computer program product are also disclosed.Type: GrantFiled: March 22, 2016Date of Patent: July 11, 2017Assignee: International Business Machines CorporationInventors: Ci-Wei Lan, Wen Zhu Liu, Dong Ni, Yiping Qu, Yu Wei Sun, Jie Xu, Li Yue, Ting Ting Zhang
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Publication number: 20170183760Abstract: A method for smelting magnesium quickly and continuously includes: preparing dolomite or magnesite with reductants and fluorite at a predetermined ratio, uniformly mixing the prepared ingredients to obtain pellets, and calcining the obtained pellets in an argon or nitrogen atmosphere; continuously feeding the high-temperature calcined pellets (without being cooled) under argon protection into a reduction furnace, and performing a high-temperature reduction reaction in a flowing argon atmosphere to obtain high-temperature magnesium steam; and enabling the high-temperature magnesium steam to be carried out of the high-temperature reduction furnace by an argon flow, and performing condensation to obtain metal magnesium. The present invention eliminates a vacuum system and a vacuum reduction tank, so that quick and continuous production of the metal magnesium is realized, the reduction time is shortened to 90 min or less, and the recovery rate of magnesium is increased to 88% or more.Type: ApplicationFiled: August 26, 2014Publication date: June 29, 2017Inventors: Ting'an ZHANG, Zhihe DOU, Zimu ZHANG, Yan LIU, Guozhi LV, Jicheng HE
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Publication number: 20170174674Abstract: Disclosed are compounds of Formula A, or a salt thereof: wherein R1, R2, and E are defined herein, which compounds have properties for inhibiting Nav 1.7 ion channels found in peripheral and sympathetic neurons. Also described are pharmaceutical formulations comprising the compounds of Formula A or their salts, and methods of treating pain disorders, cough, and itch using the same.Type: ApplicationFiled: December 14, 2016Publication date: June 22, 2017Applicant: Merck Sharp & Dohme Corp.Inventors: Thomas J. Greshock, James Mulhearn, Junying Zheng, Ronald M. Kim, Ting Zhang, Anthony J. Roecker, Walter Won, Philippe Nantermet, Rajan Anand, Gang Zhou, Deping Wang, Liangqin Guo
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Publication number: 20170129880Abstract: In its many embodiments, the present invention provides a novel class of benzamide compounds represented by Formula (I) or pharmaceutically acceptable salts or solvates thereof, or pharmaceutical compositions comprising one or more said compounds or pharmaceutically acceptable salts or solvates thereof, and methods for using said compounds or pharmaceutically acceptable salts or solvates thereof for treating or preventing a thromboses, embolisms, hypercoagulability or fibrotic changes.Type: ApplicationFiled: April 10, 2015Publication date: May 11, 2017Inventors: Isao Sakurada, Tomokazu Hirabayashi, Yoshitaka Maeda, Hiroshi Nagasue, Takashi Mizuno, Jiayi Xu, Ting Zhang, Cameron Smith, Dann Parker
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Publication number: 20170098390Abstract: A real-time multimodal image perception system to transform the standard lab blood smear image for persons with BVI to perceive, employing a combination of auditory, haptic, and vibrotactile feedbacks. These sensory feedbacks are used to convey visual information in appropriate perceptual channels, thus creating a palette of multimodal, sensorial information. A Bayesian network is provided to characterize images through two groups of features of interest: primary and peripheral features. A method is provided for optimal matching between primary features and sensory modalities.Type: ApplicationFiled: October 3, 2016Publication date: April 6, 2017Applicant: Purdue Research FoundationInventors: Bradley S. Duerstock, Juan P. Wachs, Ting Zhang, Greg Williams
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Patent number: 9591055Abstract: A method, an apparatus, and a system for remotely controlling an electronic apparatus are provided. In the method, a control apparatus discovers at least one response apparatus in the same network and obtains an apparatus description of each response apparatus. According to a command list in the apparatus description, the control apparatus sends a control message requesting a service in the command list to the response apparatus, so as to control the response apparatus to execute an operation corresponding to the control message. Here, the command list records a plurality of services provided by the response apparatus.Type: GrantFiled: May 3, 2013Date of Patent: March 7, 2017Assignee: Wistron CorporationInventor: Ying-Ting Zhang
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Publication number: 20170027916Abstract: In its many embodiments, the present invention provides a novel class of benzamide compounds represented by Formula (I) or pharmaceutically acceptable salts or solvates thereof, or pharmaceutical compositions comprising one or more said compounds or pharmaceutically acceptable salts or solvates thereof, and methods for using said compounds or pharmaceutically acceptable salts or solvates thereof for treating or preventing a thromboses, embolisms, hypercoagulability or fibrotic changes.Type: ApplicationFiled: April 10, 2015Publication date: February 2, 2017Applicants: Merck Sharp & Dohme Corp., Mochida Pharmaceutical Co., Ltd.Inventors: Isao Sakurada, Tomokazu Hirabayashi, Yoshitaka Maeda, Hiroshi Nagasue, Takashi Mizuno, Jiayi Xu, Ting Zhang, Cameron Smith, Dann Parker
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Publication number: 20170017480Abstract: The invention discloses a method for updating an application in a user terminal, comprising: acquiring information of an application installed by a user in a terminal; and sending the information of the application installed by the user in the terminal to a server to be stored in an account of the user; wherein the information of the application is used for being pushed by the server to another terminal used by the user. In addition, the invention further discloses an apparatus for updating an application in a user terminal. With the invention, when a user installs a new application and/or updates an installed application in a terminal used by him, the user may be prompted to install and/or update the same application in other terminal used by him.Type: ApplicationFiled: December 10, 2014Publication date: January 19, 2017Inventor: Ting ZHANG