Patents by Inventor Walter Pfefferle

Walter Pfefferle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200239938
    Abstract: The present invention relates to an in vitro method for guiding measures against the propagation of Salmonella and/or against the propagation Campylobacter in an animal flock, the method comprising i.) determining the amount of at least one marker gene being specific for Salmonella or Campylobacter in a test sample and ii.) comparing the amount of said at least one marker gene being specific for Salmonella or Campylobacter determined in the test sample with a control sample, wherein an increase in the amount of said at least one marker gene being specific for Salmonella or Campylobacter in the test sample vs. the control sample by at least a factor of two, indicates the necessity of initiating or enhancing measures against the propagation of Salmonella and/or against the propagation Campylobacter.
    Type: Application
    Filed: September 28, 2018
    Publication date: July 30, 2020
    Applicant: EVONIK OPERATIONS GMBH
    Inventors: Andreas KAPPEL, Florian BÖHL, Walter PFEFFERLE, Stefan PELZER, Emeka Ignatius IGWE, Frank THIEMANN
  • Patent number: 8334126
    Abstract: The invention relates to an isolated polynucleotide having a polynucleotide sequence which codes for the alr gene, and a host-vector system having a coryneform host bacterium in which the alr gene is present in attenuated form and a vector which carries at least the alr gene according to SEQ ID No 1, and the use of polynucleotides which comprise the sequences according to the invention as hybridization probes.
    Type: Grant
    Filed: September 22, 2011
    Date of Patent: December 18, 2012
    Assignee: Evonik Degussa GmbH
    Inventors: Andreas Tauch, Michael Binder, Walter Pfefferle, Georg Thierbach, Jörn Kalinowski, Alfred Pühler
  • Publication number: 20120064582
    Abstract: The invention relates to an isolated polynucleotide having a polynucleotide sequence which codes for the alr gene, and a host-vector system having a coryneform host bacterium in which the alr gene is present in attenuated form and a vector which carries at least the alr gene according to SEQ ID No 1, and the use of polynucleotides which comprise the sequences according to the invention as hybridization probes.
    Type: Application
    Filed: September 22, 2011
    Publication date: March 15, 2012
    Inventors: Andreas Tauch, Michael Binder, Walter Pfefferle, Georg Thierbach, Jörn Kalinowski, Alfred Pühler
  • Patent number: 8048665
    Abstract: The invention relates to an isolated polynucleotide having a polynucleotide sequence which codes for the alr gene, and a host-vector system having a coryneform host bacterium in which the alr gene is present in attenuated form and a vector which carries at least the alr gene according to SEQ ID No 1, and the use of polynucleotides which comprise the sequences according to the invention as hybridization probes.
    Type: Grant
    Filed: November 27, 2002
    Date of Patent: November 1, 2011
    Assignee: Evonik Degussa GmbH
    Inventors: Andreas Tauch, Michael Binder, Walter Pfefferle, Georg Thierbach, Jörn Kalinowski, Alfred Pühler
  • Patent number: 7981640
    Abstract: L-lysine-producing strains of corynebacteria with enhanced lysE gene (lysine export carrier gene), in which strains additional genes chosen from the group comprising the dapA gene (dihydrodipicolinate synthase gene), the lysC gene (aspartate kinase gene), the dapB gene (dihydrodipicolinate reductase gene) and the pyc gene, but especially the dapA gene and the lysC gene (aspartate kinase gene), are enhanced and, in particular, over-expressed, and a process for the preparation of L-lysine.
    Type: Grant
    Filed: October 10, 2008
    Date of Patent: July 19, 2011
    Assignee: Evonik Degussa GmbH
    Inventors: Caroline Kruetzer, Stephan Hans, Mechthild Rieping, Bettina Mockel, Walter Pfefferle, Lothar Eggeling, Sahm Hermann, Miroslav Patek
  • Publication number: 20100261233
    Abstract: L-lysine-producing strains of corynebacteria with enhanced lysE gene (lysine export carrier gene), in which strains additional genes chosen from the group comprising the dapA gene (dihydrodipicolinate synthase gene), the lysC gene (aspartate kinase gene), the dapB gene (dihydrodipicolinate reductase gene) and the pyc gene, but especially the dapA gene and the lysC gene (aspartate kinase gene), are enhanced and, in particular, over-expressed, and to a process for the preparation of L-lysine.
    Type: Application
    Filed: October 10, 2008
    Publication date: October 14, 2010
    Applicant: Evonik Degussa GmbH
    Inventors: Caroline Kreutzer, Stephan Hans, Mechthild Rieping, Bettina Mockel, Walter Pfefferle, Lothar Eggeling, Hermann Sahm, Miroslav Patek
  • Publication number: 20100190653
    Abstract: The invention relates to an isolated polynucleotide having a polynucleotide sequence which codes for the alr gene, and a host-vector system having a coryneform host bacterium in which the alr gene is present in attenuated form and a vector which carries at least the alr gene according to SEQ ID No 1, and the use of polynucleotides which comprise the sequences according to the invention as hybridization probes.
    Type: Application
    Filed: November 27, 2002
    Publication date: July 29, 2010
    Inventors: Andreas Tauch, Michael Binder, Walter Pfefferle, Georg Thierbach, Jorn Kalinowski, Alfred Puhler
  • Patent number: 7759056
    Abstract: The invention relates to an isolated polynucleotide from coryneform bacteria containing at least one polynucleotide sequence selected from the group consisting of a) polynucleotide which is at least 70% identical to a polynucleotide which encodes a polypeptide containing the amino acid sequence according to SEQ ID no. 2, b) polynucleotide which encodes a polypeptide which contains an amino acid sequence which is at least 70% identical to the amino acid sequence of SEQ ID no. 2, c) polynucleotide which is complementary to the polynucleotides of a) or b), and d) polynucleotide containing at least 15 successive nucleotides of the polynucleotide sequences of a), b) or c), and to a process for the fermentative production of L-amino acids, in particular L-lysine.
    Type: Grant
    Filed: December 29, 2003
    Date of Patent: July 20, 2010
    Assignee: Evonik Degussa GmbH
    Inventors: Bettina Möckel, Anke Weissenborn, Walter Pfefferle, Michael Hartmann, Jörn Kalinowski, Alfred Pühler
  • Publication number: 20100009035
    Abstract: The invention relates to sulfur-containing animal-feed additives produced from fermentation liquors, and to processes for their production.
    Type: Application
    Filed: December 14, 2007
    Publication date: January 14, 2010
    Applicant: DEGUSSA AG
    Inventors: Michael BUCHHOLZ, Michael Binder, Thomas Hermann, Walter Pfefferle, Georg Thierbach
  • Patent number: 7524657
    Abstract: The invention relates to alleles of the sigA gene from coryneform bacteria which code for sigma factors A and a process for the fermentative preparation of L-lysine using bacteria which contain these alleles.
    Type: Grant
    Filed: October 16, 2002
    Date of Patent: April 28, 2009
    Assignee: Evonik Degussa GmbH
    Inventors: Brigitte Bathe, Stephan Hans, Caroline Reynen, Walter Pfefferle
  • Patent number: 7435584
    Abstract: The invention relates to L-lysine-producing strains of corynebacteria with enhanced lysE gene (lysine export carrier gene), in which strains additional genes chosen from the group comprising the dapA gene (dihydrodipicolinate synthase gene), the lysC gene (aspartate kinase gene), the dapB gene (dihydrodipicolinate reductase gene) and the pyc gene, but especially the dapA gene and the lysC gene (aspartate kinase gene), are enhanced and, in particular, over-expressed, and to a process for the preparation of L-lysine.
    Type: Grant
    Filed: June 19, 2006
    Date of Patent: October 14, 2008
    Assignee: Evonik Degussa GmbH
    Inventors: Caroline Kruetzer, Stephan Hans, Mechthild Rieping, Bettina Mockel, Walter Pfefferle, Lothar Eggeling, Sahm Hermann, Miroslav Patek
  • Patent number: 7416863
    Abstract: Isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of a) polynucleotide which is identical to the extent of at least 70% to a polynucleotide which codes for a polypeptide which comprises the amino acid sequence of SEQ ID No. 2, b) polynucleotide which codes for a polypeptide which comprises an amino acid sequence which is identical to the extent of at least 70% to the amino acid sequence of SEQ ID No. 2, c) polynucleotide which is complementary to the polynucleotides of a) or b), and d) polynucleotide comprising at least 15 successive nucleotides of the polynucleotide sequence of a), b) or c), and a process for the fermentative preparation of L-amino acids using coryneform bacteria in which at least the lysR2 gene is present in attenuated form, and the use of the polynucleotide sequences as hybridization probes.
    Type: Grant
    Filed: July 12, 2005
    Date of Patent: August 26, 2008
    Assignee: Degussa AG
    Inventors: Bettina Moeckel, Mike Farwick, Thomas Hermann, Caroline Kreutzer, Walter Pfefferle
  • Patent number: 7348037
    Abstract: The invention relates to sulfur-containing animal-feed additives produced from fermentation liquors, and to processes for their production.
    Type: Grant
    Filed: August 11, 2003
    Date of Patent: March 25, 2008
    Assignee: Evonik Degussa GmbH
    Inventors: Michael Buchholz, Michael Binder, Thomas Hermann, Walter Pfefferle, Georg Thierbach
  • Patent number: 7306939
    Abstract: The invention provides nucleotide sequences of the gpm gene which encode phosphoglycerate mutase, and fermentation processes for the preparation of amino acids, especially L-lysine, using corynebacteria wherein the gpm gene is amplified.
    Type: Grant
    Filed: November 29, 2000
    Date of Patent: December 11, 2007
    Assignee: Degussa GmbH
    Inventors: Bettina Möckel, Walter Pfefferle
  • Patent number: 7262036
    Abstract: Disclosed herein is an isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of a) polynucleotide which is identical to the extent of at least 70% to a polynucleotide which codes for a polypeptide which comprises the amino acid sequence of SEQ ID NO:2, b) polynucleotide which codes for a polypeptide which comprises an amino acid sequence which is identical to the extent of at least 70% to the amino acid sequence of SEQ ID NO:2 c) polynucleotide which is complementary to the polynucleotides of a) and b) and d) polynucleotide comprising at least 15 successive nucleotides of the polynucleotide sequence of a), b) or c), and processes for the fermentative preparation of L-amino acid with amplification of the zwa1 gene in the coryneform bacteria employed.
    Type: Grant
    Filed: May 22, 2006
    Date of Patent: August 28, 2007
    Assignee: Degussa AG
    Inventors: Bettina Hädrich, Walter Pfefferle, Achim Marx, Jörn Kalinowski, Brigitte Bathe, Alfred Pühler
  • Patent number: 7252977
    Abstract: The invention relates to an isolated polynucleotide from Corynebacterium glutamicum having a polynucleotide sequence which encodes the sugar import protein K (msiK) gene, and a host-vector system having a coryneform host bacterium in which the msiK gene is present in enhanced form and a vector which carries at least the msiK gene according to SEQ ID No 1, and the use of polynucleotides which comprise the sequences according to the invention as hybridization probes.
    Type: Grant
    Filed: September 26, 2001
    Date of Patent: August 7, 2007
    Assignee: Degussa AG
    Inventors: Brigitte Bathe, Natalie Schischka, Mike Farwick, Walter Pfefferle
  • Publication number: 20070122832
    Abstract: The invention relates to isolated polynucleotides comprising a polynucleotide sequence chosen from the group consisting of a) polynucleotide which is identical to the extent of at least 70% to a polynucleotide which codes for a polypeptide which comprises the amino acid sequence of SEQ ID No. 2, b) polynucleotide which codes for a polypeptide which comprises an amino acid sequence which is identical to the extent of at least 70% to the amino acid sequence of SEQ ID No. 2, c) polynucleotide which is complementary to the polynucleotides of a) or b), and d) polynucleotide comprising at least 15 successive nucleotides of the polynucleotide sequence of a), b) or c), and a process for the fermentative preparation of L-amino acids using coryneform bacteria in which at least the citA gene is present in attenuated form, and the use of polynucleotides which comprise the sequences according to the invention as hybridization probes.
    Type: Application
    Filed: December 22, 2006
    Publication date: May 31, 2007
    Inventors: Bettina Mockel, Mike Farwick, Thomas Hermann, Achim Marx, Walter Pfefferle
  • Patent number: 7205131
    Abstract: The invention relates to an isolated polynucleotide containing a polynucleotide sequence selected from the group comprising a) polynucleotide which is at least 70% identical to a polynucleotide which codes for a polypeptide containing the amino acid sequence of SEQ ID no. 2, b) polynucleotide which codes for a polypeptide containing an amino acid sequence which is at least 70% identical to the amino acid sequence of SEQ ID no.2, c) polynucleotide which is complementary to the polynucleotides of a) or b), and d) polynucleotide containing at least 15 successive nucleotides of the polynucleotide sequence of a), b) or c), and a process for the fermentative production of L-amino acids with enhancement of the ptsH gene coding for component H of the phosphotransferase system, and the use of the above polynucleotides as primer or hybridisation probe.
    Type: Grant
    Filed: August 12, 2004
    Date of Patent: April 17, 2007
    Assignee: Degussa GmbH
    Inventors: Mike Farwick, Bettina Möckel, Walter Pfefferle
  • Patent number: 7205144
    Abstract: The invention related to an isolated nucleic acid consisting of a fragment of the polynucleotide of Corynebacterium glutamicum citA gene or a fragment of the full complement of the polynucleotide of the C. glutamicum citA gene wherein said fragment is at least 30 consecutive nucleotide in length, and the vector and host cell harboring these nucleic acids.
    Type: Grant
    Filed: November 1, 2004
    Date of Patent: April 17, 2007
    Assignee: Degussa AG
    Inventors: Bettina Mockel, Mike Farwick, Thomas Hermann, Achim Marx, Walter Pfefferle
  • Patent number: 7202061
    Abstract: The invention relates to an isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of a) polynucleotide which is identical to the extent of at least 70% to a polynucleotide which codes for a polypeptide which comprises the amino acid sequence of SEQ ID No. 2, b) polynucleotide which codes for a polypeptide which comprises an amino acid sequence which is identical to the extent of at least 70% to the amino acid sequence of SEQ ID No. 2, c) polynucleotide which is complementary to the polynucleotides of a) or b), and d) polynucleotide comprising at least 15 successive nucleotides of the polynucleotide sequence of a), b) or c), and a process for the fermentative preparation of L-amino acids using coryneform bacteria in which at least the mikE17 gene is present in attenuated form, and the use of polynucleotides which comprise the sequences according to the invention as hybridization probes.
    Type: Grant
    Filed: August 24, 2004
    Date of Patent: April 10, 2007
    Assignee: Degussa GmbH
    Inventors: Mike Farwick, Klaus Hutchmacher, Walter Pfefferle