Patents by Inventor Walter Pfefferle

Walter Pfefferle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pourable feed additives containing D-pantothenic acid and/or salts thereof, and process for their preparation
    Patent number: 6479084
    Abstract: A composition including at least one of D-pantothenic acid and a salt of D-panthothenic acid, greater than 50 percent of non-biomass constituents of a D-pantothenic fermentation liquor, and 0 to 100% of the biomass from D-pantothenic fermentation liquor wherein composition is a solid, pourable composition in the form of particles.
    Type: Grant
    Filed: January 30, 2002
    Date of Patent: November 12, 2002
    Assignee: Degussa AG
    Inventors: Michael Binder, Matthias Moll, Dieter Greissinger, Alexander Moeller, Walter Pfefferle
  • Nucleotide sequences which code for the chrA gene
    Publication number: 20020155554
    Abstract: The invention relates to an isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of
    Type: Application
    Filed: April 4, 2001
    Publication date: October 24, 2002
    Inventors: Brigitte Bathe, Natalie Schischka, Achim Marx, Walter Pfefferle
  • Nucleotide sequences which code for the pgsA2 gene
    Publication number: 20020155555
    Abstract: The invention relates to a genetically modified coryneform bacterium, the pgsA2 gene of which is amplified, and an isolated polynucleotide which codes for CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase from coryneform bacteria, and also a method for the fermentative preparation of L-amino acids with amplification of the pgsA2 gene in the bacteria and the use of the polynucleotide as a primer or hydridization probe.
    Type: Application
    Filed: May 16, 2001
    Publication date: October 24, 2002
    Inventors: Madhavan Nampoothiri K., Bettina Mockel, Walter Pfefferle, Lothar Eggeling, Hermann Sahm
  • Nucleotide sequences which code for the rpsL gene
    Publication number: 20020155557
    Abstract: An isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of
    Type: Application
    Filed: February 15, 2002
    Publication date: October 24, 2002
    Applicant: DEGUSSA AG
    Inventors: Bettina Moeckel, Brigitte Bathe, Stefan Hans, Caroline Kreutzer, Thomas Hermann, Walter Pfefferle, Michael Binder
  • Method to monitor a fermentation process
    Publication number: 20020151700
    Abstract: The present invention provides arrays of single- or doublestranded desoxyribonucleic acid (DNA) probes immobilized on solid supports and for using those probe arrays to detect specific nucleic acid sequences contained in a target nucleic acid in a sample, especially a method to monitore a fermentation process.
    Type: Application
    Filed: July 17, 2001
    Publication date: October 17, 2002
    Inventors: Mike Farwick, Jennifer Brehme, Thomas Hermann, Brigitte Bathe, Achim Marx, Bettina Mockel, Mechthild Rieping, Eugen Ermantraut, Thomas Ellinger, Klaus Huthmacher, Walter Pfefferle
  • Nucleotide sequences coding for the sigC gene
    Publication number: 20020146782
    Abstract: The invention relates to an isolated polynucleotide having a polynucleotide sequence which codes for the sigC gene, and a host-vector system having a coryneform host bacterium in which the sigC gene is present in attenuated form and a vector which carries at least the sigC gene according to SEQ ID No 1, and the use of polynucleotides which comprise the sequences according to the invention as hybridization probes.
    Type: Application
    Filed: August 30, 2001
    Publication date: October 10, 2002
    Inventors: Brigitte Bathe, Stephan Hans, Mike Farwick, Thomas Hermann, Walter Pfefferle
  • Nucleotide sequences which code for the atr43 gene
    Publication number: 20020142404
    Abstract: The invention relates to an isolated polynucleotide having a polynucleotide sequence which codes for the atr43 gene, and a host-vector system having a coryneform host bacterium in which the atr43 gene is present in attenuated form and a vector which carries at least the atr43 gene according to SEQ ID No 1, and the use of polynucleotides which comprise the sequences according to the invention as hybridization probes.
    Type: Application
    Filed: September 14, 2001
    Publication date: October 3, 2002
    Inventors: Mike Farwick, Klaus Huthmacher, Walter Pfefferle
  • Process for the enzymatic production of D-pantothenic acid and/or its salts
    Publication number: 20020137148
    Abstract: A process for the enzymatic production of D-pantothenic acid and/or its salts or feedstuffs additives containing the latter by fermentation of microorganisms of the family Enterobacteriaceae, in particular those that already produce D-pantothenic acid, wherein the nucleotide sequence(s) coding for the serC gene is/are enhanced, in particular overexpressed, in the microorganisms.
    Type: Application
    Filed: January 23, 2002
    Publication date: September 26, 2002
    Applicant: DEGUSSA AG
    Inventors: Mechthild Rieping, Thomas Hermann, Walter Pfefferle
  • Nucleotide sequences which code for the tmk gene
    Publication number: 20020137065
    Abstract: The invention relates to polynucleotides comprising polynucleotide sequences corresponding to the tmk gene and parts thereof that encode polypeptide sequences and parts thereof possessing varying degrees of thymidylate kinase activity, methods for preparation of L-amino acids, and methods of screening and amplifying polynucleotides encoding polypeptide sequences which comprise varying degrees of thymidylate kinase activity.
    Type: Application
    Filed: September 19, 2001
    Publication date: September 26, 2002
    Applicant: DEGUSSA AG
    Inventors: Mike Farwick, Klaus Huthmacher, Achim Marx, Walter Pfefferle
  • Process for the fermentative preparation of D-pantothenic acid and/or its salts
    Publication number: 20020137149
    Abstract: A method for the fermentative preparation of D-pantothenic acid and/or its salts or feedstuffs additives containing these by the fermentation of microorganisms from the Enterobacteriaceae family in particular those which already produce D-pantothenic acid, wherein the nucleotide sequence(s) coding for the glyA gene is enhanced in the microorganisms, in particular is overexpressed.
    Type: Application
    Filed: January 23, 2002
    Publication date: September 26, 2002
    Applicant: DEGUSSA AG
    Inventors: Thomas Hermann, Achim Marx, Walter Pfefferle, Mechthild Rieping
  • Pourable feed additives containing D-pantothenic acid and/or salts thereof, and process for their preparation
    Publication number: 20020136801
    Abstract: A composition including at least one of D-pantothenic acid and a salt of D-panthothenic acid, greater than 50 percent of non-biomass constituents of a D-pantothenic fermentation liquor, and 0 to 100% of the biomass from D-pantothenic fermentation liquor wherein composition is a solid, pourable composition in the form of particles.
    Type: Application
    Filed: January 30, 2002
    Publication date: September 26, 2002
    Applicant: DEGUSSA AG
    Inventors: Michael Binder, Matthias Moll, Dieter Greissinger, Alexander Moeller, Walter Pfefferle
  • Nucleotide sequences which code for the cstA gene
    Publication number: 20020137912
    Abstract: The invention relates to an isolated polynucleotide having a polynucleotide sequence which codes for the cstA gene, and a host-vector system having a coryneform host bacterium in which the cstA gene is present in attenuated form and a vector which carries at least the cstA gene according to SEQ ID No 1, and the use of polynucleotides which comprise the sequences according to the invention as hybridization probes.
    Type: Application
    Filed: August 24, 2001
    Publication date: September 26, 2002
    Inventors: Bettina Mockel, Achim Marx, Walter Pfefferle, Mike Farwick, Thomas Hermann
  • Nucleotide sequences coding for the PTSI protein
    Publication number: 20020132323
    Abstract: The present invention provides nucleotide sequences from Coryneform bacteria which code for the PtsI protein and a process for the fermentative preparation of amino acids using bacteria in which the ptsI gene is enhanced.
    Type: Application
    Filed: September 13, 2001
    Publication date: September 19, 2002
    Applicant: DEGUSSA AG
    Inventors: Bettina Moeckel, Stephan Hans, Natalie Schischka, Walter Pfefferle
  • Nucleotide sequences which code for the zwa1 gene
    Publication number: 20020127663
    Abstract: The invention relates to an isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of
    Type: Application
    Filed: December 8, 2000
    Publication date: September 12, 2002
    Inventors: Bettina Mockel, Walter Pfefferle, Achim Marx, Jorn Kalinowski, Brigitte Bathe, Alfred Puhler
  • Nucleotide sequences coding for the sugA gene
    Publication number: 20020127661
    Abstract: The invention relates to an isolated polynucleotide containing a polynucleotide sequence selected from the group
    Type: Application
    Filed: September 14, 2001
    Publication date: September 12, 2002
    Applicant: DEGUSSA AG
    Inventors: Mike Farwick, Klaus Huthmacher, Walter Pfefferle, Thomas Hermann, Achim Marx
  • Nucleotide sequences which code for the rpoB gene
    Publication number: 20020119537
    Abstract: The present invention relates to polynucleotides corresponding to the rpoB gene and which encode the &bgr;-subunit of RNA polymerase B, methods of producing L-amino acids, and methods of screening for polynucleotides which encode proteins having activity of the &bgr;-subunit of RNA polymerase B.
    Type: Application
    Filed: June 25, 2001
    Publication date: August 29, 2002
    Applicant: DEGUSSA AG
    Inventors: Bettina Moeckel, Brigitte Bathe, Thomas Hermann, Walter Pfefferle, Michael Binder
  • Nucleotide sequences which code for the RPSL gene
    Publication number: 20020119549
    Abstract: The present invention relates to polynucleotides corresponding to the rpsL gene and which encode ribosomal protein S12, methods of producing L-amino acids, and methods of screening for polynucleotides which encode proteins having ribosomal protein S12 activity.
    Type: Application
    Filed: October 31, 2001
    Publication date: August 29, 2002
    Applicant: DEGUSSA AG
    Inventors: Bettina Moeckel, Brigitte Bathe, Hans Stephan, Caroline Kreutzer, Thomas Hermann, Walter Pfefferle, Michael Binder
  • Nucleotide sequences which code for the truB gene
    Publication number: 20020115160
    Abstract: The invention relates to an isolated polynucleotide having a polynucleotide sequence which codes for the truB gene, and a host-vector system having a coryneform host bacterium in which the truB gene is present in attenuated form and a vector which carries at least the truB gene according to SEQ ID No 1, and the use of polynucleotides which comprise the sequences according to the invention as hybridization probes.
    Type: Application
    Filed: September 27, 2001
    Publication date: August 22, 2002
    Inventors: Mike Farwick, Klaus Huthmacher, Walter Pfefferle, Brigitte Bathe
  • Nucleotide sequences which code for the deaD gene
    Publication number: 20020115161
    Abstract: The invention relates to an isolated polynucleotide having a polynucleotide sequence which codes for the deaD gene, and a host-vector system having a coryneform host bacterium in which the deaD gene is present in attenuated form and a vector which carries at least the deaD gene according to SEQ ID No 1, and the use of polynucleotides which comprise the sequences according to the invention as hybridization probes.
    Type: Application
    Filed: September 27, 2001
    Publication date: August 22, 2002
    Inventors: Mike Farwick, Klaus Huthmacher, Jennifer Brehme, Walter Pfefferle
  • Nucleotide sequences coding for the ATR61protein
    Publication number: 20020115159
    Abstract: The invention provides nucleotide sequences from Coryneform bacteria which code for the Atr61 protein and a process for the fermentative preparation of amino acids using bacteria in which the atr61 gene is enhanced.
    Type: Application
    Filed: September 17, 2001
    Publication date: August 22, 2002
    Applicant: DEGUSSA AG
    Inventors: Mike Farwick, Klaus Huthmacher, Walter Pfefferle