Abstract: The present invention discloses a fastening device, comprising a main body and a holding part, wherein the main body constitutes a main plane, and the holding part and the main body are rotatably connected to each other; and the holding part comprises a first arm and a second arm, the first arm is provided with a first connection mechanism and a second connection mechanism, the first arm is rotatably connected to the main body via the first connection mechanism, and the second arm is rotatably connected to the first arm via the second connection mechanism. Such a fastening device can be used for the installation of floorings. Not only can the height of a handle be changed, but also the angle at which the handle is held can be changed at the same time. Moreover, the fastening device is further provided with a detachable auxiliary moving device, which can easily move a base during use, but the auxiliary moving device can be removed when it is not needed, which is convenient for packaging and transportation.

Abstract: A method and an apparatus for displaying interactive information in a panoramic video are disclosed. The method includes determining a first interactive information display area corresponding to a perspective of a first camera position of the panoramic video; and displaying first interactive information in the first interactive information display area corresponding to the perspective of the first camera position when playing an image associated with the perspective of the first camera position. According to the present disclosure, a display position of the first interactive information is not changed along with a head turning action of a user, etc. As such, when the user wants to see the first interactive information, the user can adjust the line of sight to a determined position for viewing, thus increasing an attraction of the first interactive information display area to the user, and helping to enhance the user experience.

Abstract: The present invention provides a laser ranging apparatus, including: a holder, a measuring part mounted to the holder, and a housing detachably connected to the holder, wherein the housing includes a first casing. The first casing is an integrally formed tubular structure detachably sleeved outside the holder. An advantage of the present invention is to provide a laser ranging apparatus for fixedly mounting a measuring component on a holder and installing a detachable casing on the outside of the holder so as to ensure that the position of the measuring component will not be moved during the disassembly and assembly of the casing and the ranging precision of the measuring part will not be affected. The casing is composed of several simple components, which can effectively reduce the process difficulty of the casing parts.

Abstract: The present disclosure relates generally to the fields of oncology, virology and immunotherapy. It concerns poxviruses, specifically the highly attenuated modified vaccinia virus Ankara (MVA), and a recombinant modified vaccinia Ankara virus with deletion of vaccinia virulence factor E3 (MVA?E3L), each further modified to express human Fms-like tyrosine kinase 3 ligand (Flt3L) or GM-CSF. The disclosure relates to use of the foregoing recombinant viruses as cancer immunotherapeutic agents. The foregoing recombinant poxviruses can also be used in combination with immune checkpoint blockade therapy.

Abstract: A method of manufacturing a cutting member include cutting a first metal material to form a first portion of the cutting member; cutting second metal material to form a second portion of the cutting member, wherein a first edge of the second portion has at least two line segments, a curve formed by the at least two line segments being mathematically continuously differentiable; welding the first portion and the second portion together; raising the cutting member blank to a first temperature at a first rate and holding raising the cutting member blank from the first temperature to a second temperature at a second rate lower than the first rate and holding, and raising the cutting member blank from the second temperature to a third temperature at a third rate not higher than the second rate and holding.

Abstract: Some embodiments of the present disclosure provide a knife. The knife includes a handle and a blade, the handle includes a first casing and a second casing that are detachably connected, the blade is clamped between the first casing and the second casing, the blade is provided with a plurality of limiting openings that are arranged horizontally, a limiting structure corresponding to the limiting openings is arranged on the handle, and the limiting structure has a locking position and an unlocking position; when the limiting structure is in the locking position, the blade is fixed on the handle; and when the limiting structure is in the unlocking position, the blade can move forward or backward relative to the handle.

Abstract: The present invention provides a laser ranging apparatus, including: a holder, a measuring part mounted to the holder, and a housing detachably connected to the holder, wherein the housing includes a first casing. The first casing is an integrally formed tubular structure detachably sleeved outside the holder. An advantage of the present invention is to provide a laser ranging apparatus for fixedly mounting a measuring component on a holder and installing a detachable casing on the outside of the holder so as to ensure that the position of the measuring component will not be moved during the disassembly and assembly of the casing and the ranging precision of the measuring part will not be affected. The casing is composed of several simple components, which can effectively reduce the process difficulty of the casing parts.

Abstract: The present invention relates generally to the fields of oncology, virology and immunotherapy. More particularly, it concerns the use of poxviruses, specifically the replication competent attenuated vaccinia virus with deletion of thymidine kinase (VC-TK?) with and without the expression of human Flt3L or GM-CSF as oncolytic and immunotherapy. The foregoing poxviruses can also be used in combination with immune checkpoint blocking agents. The foregoing poxviruses can also be inactivated via Heat or UV-treatment and the inactivated virus can be used as immunotherapy either alone or in combination with immune checkpoint blocking agents.

Abstract: The present application discloses a pneumatic chipping hammer, and relates to a pneumatic impact tool, which comprises a handle part, the handle part being a hollow member; a main power part, one end of the main power part being connected to the handle part, and principal axes of the handle part and the main power part forming a certain angle; and a chisel part, the chisel part being detachably connected to the other end of the main power part, wherein the direction of mounting the chisel part on the main power part can be changed. According to the pneumatic chipping hammer of the present application, the mounting direction of the chisel part on the main power part is changed by the locking member, and therefore the angle between the principal axes of the handle part and the main power part can be 5-85 degrees, so that a handle is inclined to further achieve different purposes and be suitable for people with different heights.

Abstract: Disclosed is a valve control device, comprising: a drive unit; an execution mechanism, connected to the drive unit by a transmission mechanism, attached to a valve, and configured to be able to move under the drive of the drive unit, so as to drive the valve to rotate; and a control module, connected to the drive unit, and configured to be able to control the drive unit. The valve control device according to the present invention may be mounted on an existing manually operated valve in a pipeline such as a water pipeline or a gas pipeline, and it is not necessary to remodel the existing valve and pipeline, so that the valve can be remotely, intelligently, and automatically controlled, and a water leakage situation, a gas leakage situation or the like caused by untimely response are avoided.

Abstract: An adjustable wrench includes a wrench body, a second jaw and an adjustment mechanism, the wrench body including a first jaw, a neck and a handle, wherein the first jaw is a front end of the wrench body, and the neck is located between the first jaw and the handle. The first jaw is disposed opposite the second jaw to form a holding space for holding an object. The neck is provided with a through hole, the adjustment mechanism is disposed in the through hole, and the second jaw is movably connected to the neck of the wrench body by the adjustment mechanism. The adjustment mechanism is used to adjust the movement of the second jaw relative to the first jaw. The adjustable wrench therefore includes a jaw that can move relatively fast and can also be effectively prevented from skidding or returning.

Abstract: The present invention relates generally to the fields of oncology, virology and immunotherapy. More particularly, it concerns the use of poxviruses, specifically the replication competent attenuated vaccinia virus with deletion of thymidine kinase (VC-TK?) with and without the expression of human Flt3L or GM-CSF as oncolytic and immunotherapy. The foregoing poxviruses can also be used in combination with immune checkpoint blocking agents. The foregoing poxviruses can also be inactivated via Heat or UV-treatment and the inactivated virus can be used as immunotherapy either alone or in combination with immune checkpoint blocking agents.

Abstract: The present invention provides a rivet gun including a first handle, a second handle, a transmission mechanism, and a clamping-pulling mechanism.

Abstract: The present invention discloses a method for manufacturing a screwdriver head, the screwdriver head including a head portion for being inserted into a slot of a screw head and a basal body for supporting the head portion; the manufacturing method including: providing the screwdriver head made of a first metal material; preparing alloying coating; coating the alloying coating on the surface of the head portion of the screwdriver head; conducting laser surface alloying treatment on the surface of the head portion coated with the alloying coating to form an alloyed layer; and conducting low temperature tempering treatment on the screwdriver head after the laser surface alloying treatment. The present invention further discloses a screwdriver head, the surface of the position at which the head portion of the screwdriver head contacts with the slot of the screw head is provided with an alloyed layer formed through the laser surface alloying treatment.

Abstract: The present disclosure is related to an imaging system. The imaging system may include at least one array radiation source and a detector. Each of the at least one array radiation source may include a plurality of point radiation sources. The at least one array radiation source may be configured to emit at least one radiation beam. The detector may be configured to detect at least part of the at least one radiation beam.

Abstract: Provided is a composition, which contains (A) a silane functionalized ethylene-based polymer, (B) a hindered phenol antioxidant, and (C) an aromatic amine-aromatic sulfonic acid salt. A coated conductor including a conductor and a coating which contains said composition on the conductor is also provided.

Abstract: The present disclosure relates to infection-competent, but nonreplicative inactivated modified vaccinia Ankara (MVA) and its use as immunotherapy, alone, or in combination with immune checkpoint blocking agents for the treatment of malignant solid tumors. Particular embodiments relate to inducing an immune response in a subject diagnosed with a solid malignant tumor.

Abstract: The present disclosure relates to modified vaccinia Ankara (MVA) virus or MVA?E3L delivered intratumorally or systemically as an anticancer immunotherapeutic agent, alone, or in combination with one or more immune checkpoint blocking agents for the treatment of malignant solid tumors. Particular embodiments relate to mobilizing the host's immune system to mount an immune response against the tumor.

Abstract: The present invention discloses a hand riveter and relates to the field of hand-operated tools, and the hand riveter comprises a first handle, a second handle and a clamping and pulling mechanism, wherein the second handle is capable of rotating around a pivoting shaft with respect to the first handle; the second handle is separated into a force applying end and a warping end by the pivoting shaft, and the warping end and the clamping and pulling mechanism are connected via a connecting shaft; when the force applying end of the second handle is rotated and opened with respect to the first handle, the warping end of the second handle drives the clamping and pulling mechanism to move in a rivet-driving direction; and when the force applying end of the second handle is rotated and closed with respect to the first handle, the warping end of the second handle drives the clamping and pulling mechanism to move in a rivet-pulling direction.

Abstract: The present invention discloses a movable worktable, comprising wheels, a support provided on the wheels and a table top provided on the support, wherein the table top may be opened and turned over, a first closed storage space is provided below the table top and an open storage space is provided below the first closed storage space. The present invention provides a worktable which can store various tools and is convenient to move.