Patents by Inventor William A. Barr
William A. Barr has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8945835Abstract: The invention provides methods for pairwise sequencing of a double-stranded polynucleotide template, which methods result in the sequential determination of nucleotide sequences in two distinct and separate regions of the polynucleotide template.Type: GrantFiled: April 11, 2012Date of Patent: February 3, 2015Assignee: Illumina Cambridge LimitedInventors: Eric Hans Vermaas, Graham John Worsley, Jonathan Mark Boutell, Colin Lloyd Barnes, Roberto Rigatti, Niall Anthony Gormley, Geoffrey Paul Smith, Vincent Peter Smith, Tobias William Barr Ost, David Bentley
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Publication number: 20140349891Abstract: The invention relates to methods of generating templates for a nucleic acid sequencing reaction which comprise: providing at least one double-stranded nucleic acid molecule, wherein both strands of the double-stranded nucleic acid molecule are attached to a solid support at the 5? end, cleaving one or both strands of the double-stranded nucleic acid molecule, and subjecting the cleaved strand(s) to denaturing conditions to remove the portion of the cleaved strand(s) not attached to the solid support, thereby generating a partially or substantially single-stranded template for a nucleic acid sequencing reaction,Type: ApplicationFiled: January 28, 2014Publication date: November 27, 2014Applicant: ILLUMINA CAMBRIDGE LIMITEDInventors: Xiaohai Liu, John Milton, Geoffrey Paul Smith, Colin Lloyd Barnes, Isabelle Marie Julia Rasolonjatovo, Roberto Rigatti, Xiaolin Wu, Tobias William Barr Ost, Graham John Worsley, David James Earnshaw, Gerardo Turcatti, Anthony Romieu
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Publication number: 20140336057Abstract: The invention relates to methods for pairwise sequencing of a double-stranded polynucleotide template, which methods result in the sequential determination of nucleotide sequences in two distinct and separate regions of the polynucleotide template. Using the methods of the invention it is possible to obtain two linked or paired reads of sequence information from each double-stranded template on a clustered array, rather than just a single sequencing read from one strand of the template.Type: ApplicationFiled: May 19, 2014Publication date: November 13, 2014Applicant: ILLUMINA CAMBRIDGE LIMITEDInventors: Roberto Rigatti, Tobias William Barr Ost
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Publication number: 20140304440Abstract: A method for communicating data between peripheral devices and an embedded processor that includes receiving, at a data buffer unit of the embedded processor, the data from a peripheral device. The method also includes copying data from the data buffer unit into the bridge buffer of the embedded processor as a bridge buffer message. Additionally, the method includes creating, after storing the data as a bridge buffer message, a peripheral device message comprising the bridge buffer message, and sending the peripheral device message to a thread message queue of a subscriber.Type: ApplicationFiled: April 4, 2014Publication date: October 9, 2014Applicant: WILLIAM MARSH RICE UNIVERSITYInventors: Thomas William Barr, Scott Rixner
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Publication number: 20140287415Abstract: Modified DNA polymerases have an affinity for DNA such that the polymerase has an ability to incorporate one or more nucleotides into a plurality of separate DNA templates in each reaction cycle. The polymerases are capable of forming an increased number of productive polymerase-DNA complexes in each reaction cycle. The modified polymerases may be used in a number of DNA sequencing applications, especially in the context of clustered arrays.Type: ApplicationFiled: December 20, 2013Publication date: September 25, 2014Applicant: ILLUMINA, INC.Inventors: Geoffrey Paul Smith, Roberto Rigatti, Tobias William Barr Ost, Shankar Balasubramanian, Raquel Maria Sanches-Kuiper
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Patent number: 8765381Abstract: The invention relates to methods for pairwise sequencing of a double-stranded polynucleotide template, which methods result in the sequential determination of nucleotide sequences in two distinct and separate regions of the polynucleotide template. Using the methods of the invention it is possible to obtain two linked or paired reads of sequence information from each double-stranded template on a clustered array, rather than just a single sequencing read from one strand of the template.Type: GrantFiled: April 4, 2013Date of Patent: July 1, 2014Assignee: Illumina Cambridge LimitedInventors: Roberto Rigatti, Tobias William Barr Ost
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Patent number: 8715966Abstract: The invention relates to methods of generating templates for a nucleic acid sequencing reaction which comprise: providing at least one double-stranded nucleic acid molecule, wherein both strands of the double-stranded nucleic acid molecule are attached to a solid support at the 5? end, cleaving one or both strands of the double-stranded nucleic acid molecule, and subjecting the cleaved strand(s) to denaturing conditions to remove the portion of the cleaved strand(s) not attached to the solid support, thereby generating a partially or substantially single-stranded template for a nucleic acid sequencing reaction.Type: GrantFiled: April 19, 2012Date of Patent: May 6, 2014Assignee: Illumina Cambridge LimitedInventors: Liu Xiaohai, John Milton, Geoffrey Paul Smith, Colin Lloyd Barnes, Isabelle Marie Julia Rasolonjatovo, Roberto Rigatti, Xiaolin Wu, Tobias William Barr Ost, Graham John Worsley, David James Earnshaw, Gerardo Turcatti, Anthony Romieu
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Publication number: 20140059917Abstract: An animal trap may include a source of compressed gas; a trigger mechanism configured to be actuated by an animal, and a kill mechanism powered by compressed gas. The trap may include two or more trigger valves connected in series. At least one trigger valve may include an opening, a valve seat surrounding the opening, a valve member having a sealing surface, and an O-ring arranged to seal between the sealing surface and the valve seat. One or more flow paths may allow gas to flow along at least part of an internal periphery of the O-ring. The trigger may include a trigger rod extending in a rest position from a mount at or near a first end thereof. The trigger rod may be mounted for pivoting movement about the mount, and may have two rotational degrees of freedom. Pivoting movement of the trigger rod in any direction away from the rest position may result in actuation of the trigger.Type: ApplicationFiled: August 26, 2013Publication date: March 6, 2014Applicant: Goodnature LimitedInventors: Craig Richard Bond, Stuart William Barr, Robert Blair van Dam
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Patent number: 8623628Abstract: Modified DNA polymerases have an affinity for DNA such that the polymerase has an ability to incorporate one or more nucleotides into a plurality of separate DNA templates in each reaction cycle. The polymerases are capable of forming an increased number of productive polymerase-DNA complexes in each reaction cycle. The modified polymerases may be used in a number of DNA sequencing applications, especially in the context of clustered arrays.Type: GrantFiled: May 10, 2006Date of Patent: January 7, 2014Assignee: Illumina, Inc.Inventors: Tobias William Barr Ost, Geoffrey Paul Smith, Shankar Balasubramanian, Roberto Rigatti, Raquel Maria Sanches
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Patent number: 8540318Abstract: In at least one embodiment, the present invention relates to a vehicle seat assembly comprising a seat frame made of structural foam and having a main body portion having a forward portion and a rearward portion, and a wire attachment bracket having a front attachment tab, a rear attachment tab, and a connecting portion extending between the front and rear attachment tabs. The front attachment tab can be securable to a vehicle floor pan to secure the forward portion of the seat frame to the vehicle floor pan, and the rear attachment tab can be securable to a vehicle floor pan to secure the rearward portion of the seat frame to the vehicle floor pan. In at least one embodiment, the vehicle seat assembly further comprises a cushion supported on the frame, with the cushion being softer than the seat frame, and a trim material disposed over the cushion.Type: GrantFiled: May 12, 2011Date of Patent: September 24, 2013Assignee: Lear CorporationInventors: Mark Allyn Folkert, William Barr, Ashford A. Galbreath, Asad S. Ali
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Publication number: 20130165327Abstract: The invention provides methods for pairwise sequencing of a double-stranded polynucleotide template, which methods result in the sequential determination of nucleotide sequences in two distinct and separate regions of the polynucleotide template.Type: ApplicationFiled: April 11, 2012Publication date: June 27, 2013Applicant: ILLUMINA CAMBRIDGE LIMITEDInventors: Eric Hans Vermaas, Graham John Worsley, Jonathan Mark Boutell, Colin Lloyd Barnes, Roberto Rigatti, Niall Anthony Gormley, Geoffrey Paul Smith, Vincent Peter Smith, Tobias William Barr Ost, David Bentley
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Patent number: 8431348Abstract: The invention relates to methods for pairwise sequencing of a double-stranded polynucleotide template, which methods result in the sequential determination of nucleotide sequences in two distinct and separate regions of the polynucleotide template. Using the methods of the invention it is possible to obtain two linked or paired reads of sequence information from each double-stranded template on a clustered array, rather than just a single sequencing read from one strand of the template.Type: GrantFiled: June 29, 2012Date of Patent: April 30, 2013Assignee: Illumina Cambridge LimitedInventors: Roberto Rigatti, Tobias William Barr Ost
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Publication number: 20120309634Abstract: The invention relates to methods for pairwise sequencing of a double-stranded polynucleotide template, which methods result in the sequential determination of nucleotide sequences in two distinct and separate regions of the polynucleotide template. Using the methods of the invention it is possible to obtain two linked or paired reads of sequence information from each double-stranded template on a clustered array, rather than just a single sequencing read from one strand of the template.Type: ApplicationFiled: June 29, 2012Publication date: December 6, 2012Applicant: ILLUMINA CAMBRIDGE LIMITEDInventors: Roberto Rigatti, Tobias William Barr Ost
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Publication number: 20120208194Abstract: The invention relates to methods of generating templates for a nucleic acid sequencing reaction which comprise: providing at least one double-stranded nucleic acid molecule, wherein both strands of the double-stranded nucleic acid molecule are attached to a solid support at the 5? end, cleaving one or both strands of the double-stranded nucleic acid molecule, and subjecting the cleaved strand(s) to denaturing conditions to remove the portion of the cleaved strand(s) not attached to the solid support, thereby generating a partially or substantially single-stranded template for a nucleic acid sequencing reaction,Type: ApplicationFiled: April 19, 2012Publication date: August 16, 2012Applicant: ILLUMINA CAMBRIDGE LIMITEDInventors: Xiaohai Liu, John Milton, Geoffrey Paul Smith, Colin Barnes, Isabelle Marie Julia Rasolonjatovo, Roberto Rigatti, Xiaolin Wu, Tobias William Barr Ost, Graham John Worsley, David James Earnshaw, Gerardo Turcatti, Anthony Romieu
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Patent number: 8236505Abstract: The invention relates to methods for pairwise sequencing of a double-stranded polynucleotide template, which methods result in the sequential determination of nucleotide sequences in two distinct and separate regions of the polynucleotide template. Using the methods of the invention it is possible to obtain two linked or paired reads of sequence information from each double-stranded template on a clustered array, rather than just a single sequencing read from one strand of the template.Type: GrantFiled: December 19, 2011Date of Patent: August 7, 2012Assignee: Illumina Cambridge LimitedInventors: Roberto Rigatti, Tobias William Barr Ost
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Publication number: 20120187739Abstract: In at least one embodiment, the present invention relates to a vehicle seat assembly comprising a seat frame made of structural foam and having a main body portion having a forward portion and a rearward portion, and a wire attachment bracket having a front attachment tab, a rear attachment tab, and a connecting portion extending between the front and rear attachment tabs. The front attachment tab can be securable to a vehicle floor pan to secure the forward portion of the seat frame to the vehicle floor pan, and the rear attachment tab can be securable to a vehicle floor pan to secure the rearward portion of the seat frame to the vehicle floor pan. In at least one embodiment, the vehicle seat assembly further comprises a cushion supported on the frame, with the cushion being softer than the seat frame, and a trim material disposed over the cushion.Type: ApplicationFiled: May 12, 2011Publication date: July 26, 2012Applicant: LEAR CORPORATIONInventors: Mark Allyn Folkert, William Barr, Ashford A. Galbreath, Asad S. Ali
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Patent number: 8192930Abstract: The invention provides methods for pairwise sequencing of a double-stranded polynucleotide template, which methods result in the sequential determination of nucleotide sequences in two distinct and separate regions of the polynucleotide template.Type: GrantFiled: February 8, 2007Date of Patent: June 5, 2012Assignee: Illumina Cambridge LimitedInventors: Eric Hans Vermaas, Graham John Worsley, Jonathan Mark Boutell, Colin Lloyd Barnes, Roberto Rigatti, Niall Anthony Gormley, Geoffrey Paul Smith, Vincent Peter Smith, Tobias William Barr Ost, David Bentley
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Publication number: 20120094848Abstract: The invention relates to methods for pairwise sequencing of a double-stranded polynucleotide template, which methods result in the sequential determination of nucleotide sequences in two distinct and separate regions of the polynucleotide template. Using the methods of the invention it is possible to obtain two linked or paired reads of sequence information from each double-stranded template on a clustered array, rather than just a single sequencing read from one strand of the template.Type: ApplicationFiled: December 19, 2011Publication date: April 19, 2012Applicant: ILLUMINA CAMBRIDGE LIMITEDInventors: Roberto Rigatti, Tobias William Barr Ost
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Patent number: 8105784Abstract: The invention relates to methods for pairwise sequencing of a double-stranded polynucleotide template, which methods result in the sequential determination of nucleotide sequences in two distinct and separate regions of the polynucleotide template. Using the methods of the invention it is possible to obtain two linked or paired reads of sequence information from each double-stranded template on a clustered array, rather than just a single sequencing read from one strand of the template.Type: GrantFiled: May 3, 2011Date of Patent: January 31, 2012Assignee: Illumina Cambridge LimitedInventors: Roberto Rigatti, Tobias William Barr Ost
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Publication number: 20110296739Abstract: An animal trap is powered by compressed gas and includes a trigger mechanism and kill mechanism. The trap is preferably self-resetting. A variety of sources of compressed gas may be used, and different kill mechanisms may also be used. The trap is particularly suited to applications where low-maintenance traps are required, because it uses a simple, reliable mechanism which can kill a number of animals over a long period of time without requiring maintenance or manual resetting.Type: ApplicationFiled: March 3, 2010Publication date: December 8, 2011Inventors: Craig Richard Bond, Robert Blair Creig, Stuart William Barr