Abstract: A moiré magnification device including a transparent substrate carrying: an array of micro-focusing elements, the focusing elements defining a focal plane; a first array of microimage elements in a first colour and a second array of microimage elements in a second colour, the first and second arrays of microimage elements are located in a plane substantially coincident with the focal plane of the focusing elements, the second array of microimage elements being laterally offset from the first. The pitches of the micro-focusing elements, first and second arrays of microimage elements and their relative locations are such that the array of micro-focusing elements cooperates with each of the first and second arrays of microimage elements to generate respective magnified versions of the microimage elements due to the moiré effect. An interruption zone is perceived between the magnified versions of the first and second microimage arrays, respectively, and exhibits no magnified versions.

Abstract: Methods of manufacturing security documents and security devices, and corresponding products, provide a lenticular device effect in a first registration zone. Viewing its appearance from two different angles in this way, the relative positioning of the focussing element array and the image array can be judged to a high degree of accuracy. If the two arrays do not have the desired relative position, this will be clearly apparent since the different first and second images will not be captured at the first and second test viewing angles.

Abstract: A security device comprises a transparent, colored element in a first region of the device and in a surface of which a first optically variable effect generating relief structure is formed. A reflection enhancing layer extends over the first optically variable effect generating relief microstructure and follows the contour of the relief, the reflection enhancing layer also being provided in a second region of the device laterally offset from the first region.

Abstract: The present invention provides improved methods for producing RPE cells from human embryonic stem cells or from other human pluripotent stem cells. The invention also relates to human retinal pigmented epithelial cells derived from human embryonic stem cells or other human multipotent or pluripotent stem cells. hRPE cells derived from embryonic stem cells are molecularly distinct from adult and fetal-derived RPE cells, and are also distinct from embryonic stem cells. The hRPE cells described herein are useful for treating retinal degenerative diseases.

Abstract: A diffractive security device is disclosed, including first and second diffractive structures defined in a carrier layer. The first diffractive structure is a diffractive zone plate structure of a continuously curved surface configured such that when the device is illuminated by on-axis light, a first diffraction pattern generated by the first diffractive structure can be viewed from at least a first side of the device at substantially all viewing angles, the first diffraction pattern exhibiting a reference point or reference line relative to which other features of the first diffraction pattern appear to move when the viewing angle is changed. The second diffractive structure is an off-axis diffractive structure configured such that when the device is illuminated by on-axis light a second diffraction pattern generated by the second diffractive structure can be viewed from at least the first side of the device at at least some off-axis viewing angles.

Abstract: A diffractive security device is disclosed including at least a first diffractive structure defined in a carrier layer. The first diffractive structure is an on-axis diffractive zone plate structure of a continuously curved surface configured such that when the device is illuminated by on-axis light a first diffraction pattern generated by the first diffractive structure can be viewed from at least a first side of the device at substantially all viewing angles, the first diffraction pattern exhibiting a reference point or reference line relative to which other features of the first diffraction pattern appear to move when the viewing angle is changed.

Abstract: A security device including a substrate carrying a surface relief optically variable effect generating structure formed by the super position of three diffractive image generating structures (rear, surface and front planes) which respond to respectively different color components or wavelength ranges of white light to generate a first, substantially achromatic image or background pattern located in a plane spaced from the surface of the substrate.

Abstract: A method of applying a pattern formed of two different materials to a pattern support layer includes: providing a die form having a surface with recesses defining the pattern; applying a first curable material to a surface first region, received in some of the first region recesses and partially filling a first region recess set; applying a second curable material to some of the surface first region, the second curable material at least partially fills the first set of the first region recesses; contacting a pattern support layer with the die form surface to cover the recesses containing both the first and second curable materials; separating the pattern support layer from the die form surface, the first and second curable materials in the covered recesses removed therefrom and retained on the pattern support layer; and curing the first and second curable materials during and/or after the second and third steps.

Abstract: A method of making a security device including: (a) forming an array of focussing elements on at least a first region of a focussing element support layer, by: (a)(i) applying a first transparent curable material either to the focussing element support layer or to a casting tool carrying a surface relief corresponding to the focussing elements, over an first sub-region of the first region and applying a second transparent curable material to a second sub-region of the first region laterally offset from the first sub-region, the first and second transparent curable materials having different optical detection characteristics from one another; (a)(ii) forming the first and second transparent curable materials with the casting tool; and (a)(iii) curing the first and second transparent curable materials in the first region, so as to retain the surface relief.

Abstract: A security substrate has: a polymer substrate having first and second surfaces; array of focussing elements; an optical adjustment layer and masking layer. The array is formed of a surface relief. The optical adjustment layer is on the transparent base layer across a second region including the first. The optical adjustment layer has a first surface contacting the surface relief and an opposing second surface having a profile not operative to focus visible light. The optical adjustment layer has a first transparent material extending across a first sub-region of the array, the first transparent material having a refractive index different from that of the transparent base layer. The security substrate has a masking layer over the optical adjustment layer across a third region of the polymer substrate, the third region defining a gap in the masking layer(s), such that functional focusing elements of the array are revealed through the gap.

Abstract: A security device is disclosed, comprising forming an array of focussing elements on first region of first surface of focussing element support layer, applying a pedestal layer comprising one transparent material onto first region of first surface of focussing element support layer applying transparent curable material to the pedestal layer or a casting tool carrying surface relief corresponding to focussing elements, over first region forming transparent curable material(s) with the casting tool bringing first surface of focussing element support layer against the casting tool that transparent curable material between the surface relief and the pedestal layer, across first region; and curing transparent curable material(s) on the pedestal layer to retain surface relief in first region; wherein focal length of focussing elements focal plane lies on first surface of focussing element support layer, or beyond first surface of focussing element support layer relative to the location of array of focussing element

Abstract: A method of manufacturing a security document, including: providing a polymer substrate having first and second surfaces; and: applying an array of focussing elements to the first surface of the polymer substrate across a first region; forming an image array by: providing a die form having a surface including an arrangement of raised areas and recessed areas defining the pattern; applying a first curable material to the surface of the die form so it substantially fills the recessed areas; bringing a pattern support layer in contact with the surface of the die form so it covers the recessed areas; separating the pattern support layer from the surface of the die form so the first curable material in the recessed areas is removed from the recessed areas and retained on the pattern support layer; and at least partly curing the first curable material in one or more curing steps.

Abstract: A method of manufacturing an image element array for a security device is disclosed.

Abstract: Disclosed herein are a retrofit device adapted to upgrade bioreactor systems that require at least partially manual addition of liquids, and a method for using the retrofit device with the bioreactor systems. The retrofit device automatically adds the liquids by weight to the bioreactor vessels according to a protocol or procedure. The retrofit device also includes a valve that in the event of power cut-off automatically closes to prevent unintentional addition of liquids.

Abstract: A security device includes: an elongate focusing structures array, the elongate axes are aligned along a first-direction, the elongate focusing structures parallel to one another periodically along a second-direction is orthogonally to the first-direction, each elongate focusing structure having an optical footprint of different elongate strips will be directed to the viewer in dependence on the viewing angle, the centre line of each optical footprint parallel with the first-direction; image elements-array overlapping the array of elongate focusing structures, the image elements-array representing elongate image slices of at least two respective images, each image slice including one or more image elements, and at least one image slice of each respective image in the optical footprint of each elongate focusing structure.

Abstract: A security device including a transparent substrate having opposing first and second surfaces; a first focusing element array disposed on the first surface of the transparent substrate; a second focusing element array disposed on the second surface of the transparent substrate; a first image array disposed on or in the transparent substrate in a first image array plane and configured to co-operate with the first focusing element array to exhibit an optically variable effect when viewed from a first side of the security device; and a second image array disposed on or in the transparent substrate in a second image array plane configured to co-operate with the second focusing element array to exhibit an optically variable effect when viewed from a second side of the security device. At least the first image array is configured to exhibit a first static macroimage when viewed from the second side of the device.

Abstract: A security element including substrate on which is disposed: in first area, a first optically variable device including a diffractive or reflective relief structure and reflection enhancing material following contours of relief structure; and, in second area, a second optically variable device including an iridescent amplitude interference material. First optically variable device is constituted by a plurality of sub-areas arranged in cyclically repeating sequence along predetermined direction of the security element, the plurality of sub-areas collectively forming first area.

Abstract: A joint having a male joint member and female joint member, in which a raised stop on the male joint member is limited to displacement between a constriction on the female joint member and a locking ring segment, and in which the locking ring segment and constriction are separated by an unobstructed traverse region that allows the male joint member to slide axially when under stress without separation from the female joint member. The rounded shape of the groove that accommodates the locking ring segment acts like a universal joint, allowing deflection between the male and female joint members without separation. The female joint member flares on the inside of its distal region to accommodate such deflection. Thus the male and female joint members have a degree of axial and radial flexibility that prevents separation under stress, such as during earth movement events such as earthquakes, floods, and landslides.

Abstract: A lenticular device includes an array of lenticular focusing elements located over a corresponding array of pairs of image strips such that, in a first viewing direction, a first image strip from each pair is viewed by respective ones of the lenticular focusing elements and, in a second viewing direction, different from the first, a second image strip from each pair is viewed by respective ones of the lenticular focusing elements, One of each pair of image strips has portions defining a first image in a first color and a second image in a second color respectively, and the other of each pair of image strips has portions defining the first image in the second color and the second image in the first color respectively, whereby on tilting the device, a color switch is observed between the first and second images.

Abstract: A method of manufacturing a pattern on a substrate web includes providing a production tool having a surface relief structure of elevations and depressions. The elevations correspond to a desired pattern. A curable material is applied to the elevations. The material is brought into contact with a substrate web at a first location. The substrate web and surface relief structure are transported together in contact from the first location to a second location spaced from one another along the transport direction of the substrate web. The substrate web is separated from the surface relief structure at the second location whereupon the material forming the pattern is affixed to and carried by the substrate web. The material is cured by exposure to a curing energy source, either between the first and second locations and/or after the substrate web has been separated from the surface relief structure at the second location.