Patents by Inventor William A. Holmes
William A. Holmes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9429762Abstract: A lenticular device includes an array of lenticular focusing elements located over a corresponding array of pairs of image strips such that, in a first viewing direction, a first image strip from each pair is viewed by respective ones of the lenticular focusing elements and, in a second viewing direction, different from the first, a second image strip from each pair is viewed by respective ones of the lenticular focusing elements, One of each pair of image strips has portions defining a first image in a first color and a second image in a second color respectively, and the other of each pair of image strips has portions defining the first image in the second color and the second image in the first color respectively, whereby on tilting the device, a color switch is observed between the first and second images.Type: GrantFiled: October 27, 2010Date of Patent: August 30, 2016Assignee: DE LA RUE INTERNATIONAL LIMITEDInventors: Brian William Holmes, Lawrence George Commander
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Publication number: 20160229174Abstract: A method of manufacturing a pattern on a substrate web includes providing a production tool having a surface relief structure of elevations and depressions. The elevations correspond to a desired pattern. A curable material is applied to the elevations. The material is brought into contact with a substrate web at a first location. The substrate web and surface relief structure are transported together in contact from the first location to a second location spaced from one another along the transport direction of the substrate web. The substrate web is separated from the surface relief structure at the second location whereupon the material forming the pattern is affixed to and carried by the substrate web. The material is cured by exposure to a curing energy source, either between the first and second locations and/or after the substrate web has been separated from the surface relief structure at the second location.Type: ApplicationFiled: September 26, 2014Publication date: August 11, 2016Applicant: De La Rue International LimitedInventor: Brian William HOLMES
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Publication number: 20160152066Abstract: A security device comprises a transparent, coloured element in a first region of the device and in a surface of which a first optically variable effect generating relief structure is formed. A reflection enhancing layer extends over the first optically variable effect generating relief microstructure and follows the contour of the relief, the reflection enhancing layer also being provided in a second region of the device laterally offset from the first region.Type: ApplicationFiled: February 3, 2016Publication date: June 2, 2016Applicant: DE LA RUE INTERNATIONAL LIMITEDInventor: Brian William HOLMES
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Patent number: 9322895Abstract: The present invention provides a novel lactate difference imaging (LDI) technique, allowing assessment of the metabolic responses of tissue over a period of time. This approach utilizes lactate change over a time period as an indicator of viable tissue, and offers benefits in the management and treatment of the effects of many common diseases, in particular stroke.Type: GrantFiled: September 3, 2010Date of Patent: April 26, 2016Assignees: Greater Glasgow Health Board, The University Court of the University of GlasgowInventors: Celestine Santosh, William Holmes, Rosario Lopez
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Patent number: 9177433Abstract: A moiré magnification device includes a transparent substrate, the transparent substrate carrying a regular array of micro-focusing elements on a first surface, where the focusing elements define a focal plane, and a corresponding array of microimage element unit cells located in a plane substantially coincident with the focal plane of the focusing elements, where each unit cell includes at least two microimage components. The pitches of the micro-focusing elements and the array of microimage element unit cells and their relative locations are such that the array of micro-focusing elements cooperates with the array of microimage element unit cells to generate magnified versions of the microimage components due to the moiré effect.Type: GrantFiled: March 1, 2011Date of Patent: November 3, 2015Assignee: DE LA RUE INTERNATIONAL LIMITEDInventor: Brian William Holmes
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Patent number: 9140507Abstract: An obturator assembly for sealing the breech of a breech-loaded cannon includes a generally annular seal, a front split ring, a rear split ring, a rear inner ring, an annular disc, and a plurality of magnets disposed in the seal. The seal has a front portion with a leading angled surface and a rear portion. The rear portion includes a trailing angled surface and a flat surface. A plurality of magnets is disposed in holes in the leading angled surface of the front portion and in the flat surface of the rear portion. Magnets in the holes in the front portion hold the front split ring in abutment with the seal. Magnets in the holes in the rear portion hold the annular disc in abutment with the rear split ring and rear inner ring. The front split ring, rear split ring, rear inner ring, and annular disc may rotate with respect to the seal when the breech is opened or closed.Type: GrantFiled: March 20, 2013Date of Patent: September 22, 2015Assignee: The United States of America as Represented by the Secretary of the ArmyInventor: Edward William Holmes
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Patent number: 9070237Abstract: A moire magnification device is disclosed, including a transparent substrate carrying: a regular array of micro-focusing elements on a first surface, the focusing elements defining a focal plane; and a corresponding first array of microimage elements located in a plane substantially coincident with the focal plane of the focusing elements. The pitches of the micro-focusing elements and the array of microimage elements and their relative locations are such that the array of micro-focusing elements cooperates with the array of microimage elements to generate magnified version of the microimage elements due to the moire effect. Along at least one axis across at least a first region of the device, the pitch between the microimage elements and/or between the micro-focusing elements continuously varies across the respective array(s), whereby the moire effect causes different degrees of magnification of the image elements to occur.Type: GrantFiled: March 1, 2011Date of Patent: June 30, 2015Assignee: DE LA RUE INTERNATIONAL LIMITEDInventor: Brian William Holmes
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Publication number: 20150086512Abstract: The present invention provides improved methods for producing RPE cells from human embryonic stem cells or from other human pluripotent stem cells. The invention also relates to human retinal pigmented epithelial cells derived from human embryonic stem cells or other human multipotent or pluripotent stem cells. hRPE cells derived from embryonic stem cells are molecularly distinct from adult and fetal-derived RPE cells, and are also distinct from embryonic stem cells. The hRPE cells described herein are useful for treating retinal degenerative diseases.Type: ApplicationFiled: April 16, 2014Publication date: March 26, 2015Applicant: Advanced Cell Technology, Inc.Inventors: Christopher Malcuit, Linda Lemieux, William Holmes, Pedro Huertas, Lucy Vilner
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Patent number: 8908276Abstract: A moiré magnification device includes a transparent substrate carrying: a regular array of micro-focusing elements, that define a focal plane, on a first surface; a corresponding first array of microimage elements in a first color located in a plane substantially coincident with the focal plane; and a corresponding second array of microimage elements, in a second color, located in a plane substantially coincident with the focal plane. The pitches of the micro-focusing elements and first and second arrays and their relative locations are such that the array of micro-focusing elements cooperates with each of the first and second arrays to generate magnified versions of the microimage elements due to the moiré effect. The magnified version of the first array is viewed against a background defined by the magnified version of the second array, the first array exhibiting movement relative to the background when the device is tilted.Type: GrantFiled: March 1, 2011Date of Patent: December 9, 2014Assignee: De La Rue International LimitedInventor: Brian William Holmes
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Patent number: 8861055Abstract: A security device having a lenticular device that includes an array of lenticular focusing elements located over a corresponding array of sets of image strips such that at different viewing directions, a corresponding image strip from each set is viewed via respective ones of the lenticular focusing elements wherein the image strips are defined at least in part by a relief structure.Type: GrantFiled: October 27, 2010Date of Patent: October 14, 2014Assignee: De La Rue International LimitedInventors: Brian William Holmes, Lawrence George Commander
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Patent number: 8794530Abstract: An optically variable magnetic stripe assembly comprises a magnetic layer (5); an optically variable effect generating layer (1) over the magnetic layer; and a metallic reflecting layer (3) adjacent the optically variable effect generating layer and comprising an array of spaced metallic regions shaped as regular polygons.Type: GrantFiled: January 23, 2008Date of Patent: August 5, 2014Assignee: Opsec Security Group Inc.Inventors: Brian William Holmes, Mark Deakes
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Patent number: 8773743Abstract: A security device comprising at least first and second superposed optically variable effect generating structures (3-5, 31-51), each having a surface relief microstructure, the second optically variable effect generating structure being viewable through the first.Type: GrantFiled: November 29, 2012Date of Patent: July 8, 2014Assignee: De La Rue International LimitedInventor: Brian William Holmes
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Patent number: 8673259Abstract: Apparatus and methods are described for separate heating of substrate, catalyst and feedstock/transport gases for the controllable CVD synthesis of various carbon nanotubes and nanostructures, and particularly for CVD growth of oriented forests of multi-wall CNT forests, which are highly dry-spinnable into sheets and yarns.Type: GrantFiled: May 11, 2011Date of Patent: March 18, 2014Assignee: Solarno Inc.Inventor: William A. Holmes
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Patent number: 8617190Abstract: A system for performing an end-to-side vascular anastomosis, including an anastomosis device, an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery, particularly in port-access CABG surgery. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member, forming the attachment with the target vessel wall and a coupling member, forming the attachment with the bypass graft vessel. The anastomosis is completed by inserting the coupling member, with the graft vessel attached, into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple.Type: GrantFiled: March 28, 2011Date of Patent: December 31, 2013Assignee: Heartport, Inc.Inventors: Hanson S. Gifford, III, Lee R. Bolduc, Jeffrey A. Stein, Paul C. DiCesare, Peter F. Costa, William A. Holmes
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Patent number: 8551673Abstract: An optically variable magnetic stripe assembly includes a magnetic layer, an optically variable effect generating layer over the magnetic layer, and an electrically non-conductive reflective layer between the magnetic layer and the optically variable effect generating layer.Type: GrantFiled: February 4, 2008Date of Patent: October 8, 2013Assignee: De La Rue International LimitedInventors: Brian William Holmes, Malcolm Robert Murray Knight, David Allen Stone
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Publication number: 20130149284Abstract: The present invention provides improved methods for producing retinal pigmented epithelial (RPE) cells from human embryonic stem cells, human induced pluripotent stem (iPS), human adult stem cells, human hematopoietic stem cells, human fetal stem cells, human mesenchymal stem cells, human postpartum stem cells, human multipotent stem cells, or human embryonic germ cells. The RPE cells derived from embryonic stem cells are molecularly distinct from adult and fetal-derived RPE cells, and are also distinct from embryonic stem cells. The RPE cells described herein are useful for treating retinal degenerative conditions including retinal detachment and macular degeneration.Type: ApplicationFiled: November 17, 2010Publication date: June 13, 2013Applicant: Advanced Cell Technlogy, Inc.Inventors: Christopher Malcuit, Linda Lemieux, William Holmes, Pedro Huertas, Lucy Vilner
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Publication number: 20130107335Abstract: A security device comprising at least first and second superposed optically variable effect generating structures (3-5, 31-51), each having a surface relief microstructure, the second optically variable effect generating structure being viewable through the first.Type: ApplicationFiled: November 29, 2012Publication date: May 2, 2013Applicant: DE LA RUE INTERNATIONAL LIMITEDInventor: Brian William HOLMES
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Publication number: 20130106092Abstract: A security device including a substrate carrying a surface relief optically variable effect generating structure formed by the super position of three diffractive image generating structures (rear, surface and front planes) which respond to respectively different colour components or wavelength ranges of white light to generate a first, substantially achromatic image or background pattern located in a plane spaced from the surface of the substrate.Type: ApplicationFiled: May 6, 2011Publication date: May 2, 2013Applicant: DE LA RUE INTERNATIONAL LIMITEDInventor: Brian William Holmes
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Patent number: 8397433Abstract: A rear edge side window catch assembly for a vehicle side window may include a rear edge side window guide and a side window catch bracket. The rear edge side window guide may include an upper end, a lower end and a substantially U-shaped channel formed by an exterior side wall and an interior side wall connected by a back wall. The channel may extend substantially the entire length between the upper end and the lower end. The side window catch bracket may include a connection section and a catch section, wherein the connection section may connect to the rear edge side window guide and the catch section may extend from the rear edge side window guide along the exterior side wall in a direction towards an opening of the channel.Type: GrantFiled: December 22, 2008Date of Patent: March 19, 2013Assignee: Toyota Motor Engineering & Manufacturing North America, Inc.Inventor: George William Holmes
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Publication number: 20130056971Abstract: A moiré magnification device including a transparent substrate carrying: an array of micro-focusing elements, the focusing elements defining a focal plane; a first array of microimage elements in a first colour and a second array of microimage elements in a second colour, the first and second arrays of microimage elements are located in a plane substantially coincident with the focal plane of the focusing elements, the second array of microimage elements being laterally offset from the first. The pitches of the micro-focusing elements, first and second arrays of microimage elements and their relative locations are such that the array of micro-focusing elements cooperates with each of the first and second arrays of microimage elements to generate respective magnified versions of the microimage elements due to the moiré effect. An interruption zone is perceived between the magnified versions of the first and second microimage arrays, respectively, and exhibits no magnified versions.Type: ApplicationFiled: March 1, 2011Publication date: March 7, 2013Applicant: DE LA RUE INTERNATIONAL LIMITEDInventor: Brian William Holmes