Patents by Inventor William A. Holmes

William A. Holmes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9429762
    Abstract: A lenticular device includes an array of lenticular focusing elements located over a corresponding array of pairs of image strips such that, in a first viewing direction, a first image strip from each pair is viewed by respective ones of the lenticular focusing elements and, in a second viewing direction, different from the first, a second image strip from each pair is viewed by respective ones of the lenticular focusing elements, One of each pair of image strips has portions defining a first image in a first color and a second image in a second color respectively, and the other of each pair of image strips has portions defining the first image in the second color and the second image in the first color respectively, whereby on tilting the device, a color switch is observed between the first and second images.
    Type: Grant
    Filed: October 27, 2010
    Date of Patent: August 30, 2016
    Assignee: DE LA RUE INTERNATIONAL LIMITED
    Inventors: Brian William Holmes, Lawrence George Commander
  • Publication number: 20160229174
    Abstract: A method of manufacturing a pattern on a substrate web includes providing a production tool having a surface relief structure of elevations and depressions. The elevations correspond to a desired pattern. A curable material is applied to the elevations. The material is brought into contact with a substrate web at a first location. The substrate web and surface relief structure are transported together in contact from the first location to a second location spaced from one another along the transport direction of the substrate web. The substrate web is separated from the surface relief structure at the second location whereupon the material forming the pattern is affixed to and carried by the substrate web. The material is cured by exposure to a curing energy source, either between the first and second locations and/or after the substrate web has been separated from the surface relief structure at the second location.
    Type: Application
    Filed: September 26, 2014
    Publication date: August 11, 2016
    Applicant: De La Rue International Limited
    Inventor: Brian William HOLMES
  • Publication number: 20160152066
    Abstract: A security device comprises a transparent, coloured element in a first region of the device and in a surface of which a first optically variable effect generating relief structure is formed. A reflection enhancing layer extends over the first optically variable effect generating relief microstructure and follows the contour of the relief, the reflection enhancing layer also being provided in a second region of the device laterally offset from the first region.
    Type: Application
    Filed: February 3, 2016
    Publication date: June 2, 2016
    Applicant: DE LA RUE INTERNATIONAL LIMITED
    Inventor: Brian William HOLMES
  • Patent number: 9322895
    Abstract: The present invention provides a novel lactate difference imaging (LDI) technique, allowing assessment of the metabolic responses of tissue over a period of time. This approach utilizes lactate change over a time period as an indicator of viable tissue, and offers benefits in the management and treatment of the effects of many common diseases, in particular stroke.
    Type: Grant
    Filed: September 3, 2010
    Date of Patent: April 26, 2016
    Assignees: Greater Glasgow Health Board, The University Court of the University of Glasgow
    Inventors: Celestine Santosh, William Holmes, Rosario Lopez
  • Patent number: 9177433
    Abstract: A moiré magnification device includes a transparent substrate, the transparent substrate carrying a regular array of micro-focusing elements on a first surface, where the focusing elements define a focal plane, and a corresponding array of microimage element unit cells located in a plane substantially coincident with the focal plane of the focusing elements, where each unit cell includes at least two microimage components. The pitches of the micro-focusing elements and the array of microimage element unit cells and their relative locations are such that the array of micro-focusing elements cooperates with the array of microimage element unit cells to generate magnified versions of the microimage components due to the moiré effect.
    Type: Grant
    Filed: March 1, 2011
    Date of Patent: November 3, 2015
    Assignee: DE LA RUE INTERNATIONAL LIMITED
    Inventor: Brian William Holmes
  • Patent number: 9140507
    Abstract: An obturator assembly for sealing the breech of a breech-loaded cannon includes a generally annular seal, a front split ring, a rear split ring, a rear inner ring, an annular disc, and a plurality of magnets disposed in the seal. The seal has a front portion with a leading angled surface and a rear portion. The rear portion includes a trailing angled surface and a flat surface. A plurality of magnets is disposed in holes in the leading angled surface of the front portion and in the flat surface of the rear portion. Magnets in the holes in the front portion hold the front split ring in abutment with the seal. Magnets in the holes in the rear portion hold the annular disc in abutment with the rear split ring and rear inner ring. The front split ring, rear split ring, rear inner ring, and annular disc may rotate with respect to the seal when the breech is opened or closed.
    Type: Grant
    Filed: March 20, 2013
    Date of Patent: September 22, 2015
    Assignee: The United States of America as Represented by the Secretary of the Army
    Inventor: Edward William Holmes
  • Patent number: 9070237
    Abstract: A moire magnification device is disclosed, including a transparent substrate carrying: a regular array of micro-focusing elements on a first surface, the focusing elements defining a focal plane; and a corresponding first array of microimage elements located in a plane substantially coincident with the focal plane of the focusing elements. The pitches of the micro-focusing elements and the array of microimage elements and their relative locations are such that the array of micro-focusing elements cooperates with the array of microimage elements to generate magnified version of the microimage elements due to the moire effect. Along at least one axis across at least a first region of the device, the pitch between the microimage elements and/or between the micro-focusing elements continuously varies across the respective array(s), whereby the moire effect causes different degrees of magnification of the image elements to occur.
    Type: Grant
    Filed: March 1, 2011
    Date of Patent: June 30, 2015
    Assignee: DE LA RUE INTERNATIONAL LIMITED
    Inventor: Brian William Holmes
  • Publication number: 20150086512
    Abstract: The present invention provides improved methods for producing RPE cells from human embryonic stem cells or from other human pluripotent stem cells. The invention also relates to human retinal pigmented epithelial cells derived from human embryonic stem cells or other human multipotent or pluripotent stem cells. hRPE cells derived from embryonic stem cells are molecularly distinct from adult and fetal-derived RPE cells, and are also distinct from embryonic stem cells. The hRPE cells described herein are useful for treating retinal degenerative diseases.
    Type: Application
    Filed: April 16, 2014
    Publication date: March 26, 2015
    Applicant: Advanced Cell Technology, Inc.
    Inventors: Christopher Malcuit, Linda Lemieux, William Holmes, Pedro Huertas, Lucy Vilner
  • Patent number: 8908276
    Abstract: A moiré magnification device includes a transparent substrate carrying: a regular array of micro-focusing elements, that define a focal plane, on a first surface; a corresponding first array of microimage elements in a first color located in a plane substantially coincident with the focal plane; and a corresponding second array of microimage elements, in a second color, located in a plane substantially coincident with the focal plane. The pitches of the micro-focusing elements and first and second arrays and their relative locations are such that the array of micro-focusing elements cooperates with each of the first and second arrays to generate magnified versions of the microimage elements due to the moiré effect. The magnified version of the first array is viewed against a background defined by the magnified version of the second array, the first array exhibiting movement relative to the background when the device is tilted.
    Type: Grant
    Filed: March 1, 2011
    Date of Patent: December 9, 2014
    Assignee: De La Rue International Limited
    Inventor: Brian William Holmes
  • Patent number: 8861055
    Abstract: A security device having a lenticular device that includes an array of lenticular focusing elements located over a corresponding array of sets of image strips such that at different viewing directions, a corresponding image strip from each set is viewed via respective ones of the lenticular focusing elements wherein the image strips are defined at least in part by a relief structure.
    Type: Grant
    Filed: October 27, 2010
    Date of Patent: October 14, 2014
    Assignee: De La Rue International Limited
    Inventors: Brian William Holmes, Lawrence George Commander
  • Patent number: 8794530
    Abstract: An optically variable magnetic stripe assembly comprises a magnetic layer (5); an optically variable effect generating layer (1) over the magnetic layer; and a metallic reflecting layer (3) adjacent the optically variable effect generating layer and comprising an array of spaced metallic regions shaped as regular polygons.
    Type: Grant
    Filed: January 23, 2008
    Date of Patent: August 5, 2014
    Assignee: Opsec Security Group Inc.
    Inventors: Brian William Holmes, Mark Deakes
  • Patent number: 8773743
    Abstract: A security device comprising at least first and second superposed optically variable effect generating structures (3-5, 31-51), each having a surface relief microstructure, the second optically variable effect generating structure being viewable through the first.
    Type: Grant
    Filed: November 29, 2012
    Date of Patent: July 8, 2014
    Assignee: De La Rue International Limited
    Inventor: Brian William Holmes
  • Patent number: 8673259
    Abstract: Apparatus and methods are described for separate heating of substrate, catalyst and feedstock/transport gases for the controllable CVD synthesis of various carbon nanotubes and nanostructures, and particularly for CVD growth of oriented forests of multi-wall CNT forests, which are highly dry-spinnable into sheets and yarns.
    Type: Grant
    Filed: May 11, 2011
    Date of Patent: March 18, 2014
    Assignee: Solarno Inc.
    Inventor: William A. Holmes
  • Patent number: 8617190
    Abstract: A system for performing an end-to-side vascular anastomosis, including an anastomosis device, an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery, particularly in port-access CABG surgery. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member, forming the attachment with the target vessel wall and a coupling member, forming the attachment with the bypass graft vessel. The anastomosis is completed by inserting the coupling member, with the graft vessel attached, into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple.
    Type: Grant
    Filed: March 28, 2011
    Date of Patent: December 31, 2013
    Assignee: Heartport, Inc.
    Inventors: Hanson S. Gifford, III, Lee R. Bolduc, Jeffrey A. Stein, Paul C. DiCesare, Peter F. Costa, William A. Holmes
  • Patent number: 8551673
    Abstract: An optically variable magnetic stripe assembly includes a magnetic layer, an optically variable effect generating layer over the magnetic layer, and an electrically non-conductive reflective layer between the magnetic layer and the optically variable effect generating layer.
    Type: Grant
    Filed: February 4, 2008
    Date of Patent: October 8, 2013
    Assignee: De La Rue International Limited
    Inventors: Brian William Holmes, Malcolm Robert Murray Knight, David Allen Stone
  • Publication number: 20130149284
    Abstract: The present invention provides improved methods for producing retinal pigmented epithelial (RPE) cells from human embryonic stem cells, human induced pluripotent stem (iPS), human adult stem cells, human hematopoietic stem cells, human fetal stem cells, human mesenchymal stem cells, human postpartum stem cells, human multipotent stem cells, or human embryonic germ cells. The RPE cells derived from embryonic stem cells are molecularly distinct from adult and fetal-derived RPE cells, and are also distinct from embryonic stem cells. The RPE cells described herein are useful for treating retinal degenerative conditions including retinal detachment and macular degeneration.
    Type: Application
    Filed: November 17, 2010
    Publication date: June 13, 2013
    Applicant: Advanced Cell Technlogy, Inc.
    Inventors: Christopher Malcuit, Linda Lemieux, William Holmes, Pedro Huertas, Lucy Vilner
  • Publication number: 20130107335
    Abstract: A security device comprising at least first and second superposed optically variable effect generating structures (3-5, 31-51), each having a surface relief microstructure, the second optically variable effect generating structure being viewable through the first.
    Type: Application
    Filed: November 29, 2012
    Publication date: May 2, 2013
    Applicant: DE LA RUE INTERNATIONAL LIMITED
    Inventor: Brian William HOLMES
  • Publication number: 20130106092
    Abstract: A security device including a substrate carrying a surface relief optically variable effect generating structure formed by the super position of three diffractive image generating structures (rear, surface and front planes) which respond to respectively different colour components or wavelength ranges of white light to generate a first, substantially achromatic image or background pattern located in a plane spaced from the surface of the substrate.
    Type: Application
    Filed: May 6, 2011
    Publication date: May 2, 2013
    Applicant: DE LA RUE INTERNATIONAL LIMITED
    Inventor: Brian William Holmes
  • Patent number: 8397433
    Abstract: A rear edge side window catch assembly for a vehicle side window may include a rear edge side window guide and a side window catch bracket. The rear edge side window guide may include an upper end, a lower end and a substantially U-shaped channel formed by an exterior side wall and an interior side wall connected by a back wall. The channel may extend substantially the entire length between the upper end and the lower end. The side window catch bracket may include a connection section and a catch section, wherein the connection section may connect to the rear edge side window guide and the catch section may extend from the rear edge side window guide along the exterior side wall in a direction towards an opening of the channel.
    Type: Grant
    Filed: December 22, 2008
    Date of Patent: March 19, 2013
    Assignee: Toyota Motor Engineering & Manufacturing North America, Inc.
    Inventor: George William Holmes
  • Publication number: 20130056971
    Abstract: A moiré magnification device including a transparent substrate carrying: an array of micro-focusing elements, the focusing elements defining a focal plane; a first array of microimage elements in a first colour and a second array of microimage elements in a second colour, the first and second arrays of microimage elements are located in a plane substantially coincident with the focal plane of the focusing elements, the second array of microimage elements being laterally offset from the first. The pitches of the micro-focusing elements, first and second arrays of microimage elements and their relative locations are such that the array of micro-focusing elements cooperates with each of the first and second arrays of microimage elements to generate respective magnified versions of the microimage elements due to the moiré effect. An interruption zone is perceived between the magnified versions of the first and second microimage arrays, respectively, and exhibits no magnified versions.
    Type: Application
    Filed: March 1, 2011
    Publication date: March 7, 2013
    Applicant: DE LA RUE INTERNATIONAL LIMITED
    Inventor: Brian William Holmes