Abstract: Systems, platforms, methods and media for providing genomic services are disclosed. In one example, a genomic services platform comprises a network interface through which genomic sequence reads derived from a biological sample obtained from a user are received. The platform also includes a bioinformatics processing pipeline that includes a read alignment module configured to receive a genomics file from genomic sequencing equipment and use data contained therein to generate observed sequence data by aligning the sequence reads relative to a reference sequence. A variant calling module identifies observed variants in the observed sequence data and stores the observed variants in a variant calling file. A variant refinement module produces genotype data including a set of refined variants associated with the user, and a variant imputation module produces a set of imputed variants associated with the user.

Abstract: Systems, platforms, methods and media for providing genomic services are disclosed. In one example, a platform comprises a network interface, in communication with a sequencing laboratory, through which are received genomic sequence reads derived from a biological sample obtained from a user, and a bioinformatics processing pipeline. The pipeline includes a read alignment module configured to generate observed sequence data by aligning the sequence reads relative to a reference sequence, a variant calling module operative to identify observed variants in the observed sequence data, a genomic data storage containing at least the observed variants in the observed sequence data, and a variant storage module disposed to receive a query from network infrastructure of a partner application provider and to provide genomic information based on or derived from the observed variants in response to the query.

Abstract: The invention provides a tool 10 of the invention for welding a PET gland 12 onto a PET bottle 14 for the fitment of a dispensing tap. The tool 10 is generically indicated as ultrasonic horn or sonotrode in the figure. The ultrasonic horn has a tapered serrated portion 16 which has a lead-in taper section 18 to initiate the melt of the plastics to be welded, and a knife section 20 (when required), being the cutting zone thereof, which in use cuts open a sealed spigot 22 so that the horn can enter into the spigot 24 for the welding operation.

Abstract: Methods, systems and media for providing genomic services are disclosed. In one example, a system for providing genomic services comprises genomic sequencing equipment configured to generate sequence reads based upon a biological sample obtained from a user, and a genomic services platform. The platform includes genomic data storage containing observed sequence data generated by aligning the sequence reads relative to a reference sequence and variants in the observed sequence data derived from the observed sequence data. File storage includes one or more files defining one or more genomic windows respectively associated with each of a plurality of partner application providers or partner applications.

Abstract: Methods, systems and media for providing genomic services are disclosed. In one example, a system comprises genomic sequencing equipment configured to generate sequence reads based upon a biological sample obtained from a user, and a genomic services platform. The platform includes a network interface through which the sequence reads are received. A bioinformatics processing pipeline includes a read alignment module configured to generate observed sequence data by aligning the sequence reads relative to a reference sequence, and a variant calling module is operative to identify observed variants in the observed sequence data. Genomic data storage contains the observed variants in the observed sequence data. A variant storage module is disposed to receive a query from network infrastructure of a partner application provider and to provide genomic information based on or derived from the observed variants in response to the query.

Abstract: A system for component based aggregation of medication orders may include a processor and memory. The processor may receive display a queue that lists medication orders to be prepared by a healthcare professional, the medication orders indicating component medications that will be used to prepare the ordered medications. The processor may receive a selection of a first medication order listed in the queue, where the first medication order indicates a first component medication. The processor may determine a second medication order listed in the queue that indicates the first component medication. The processor may reorder the displayed queue such that the second medication order is listed adjacent to the first medication order. The processor may notify the healthcare professional of the second medication order, such as by displaying an indication of the second medication order separately from the queue.

Abstract: An enclosure includes an enclosure interior and an enclosure opening through which air passes from outside the enclosure into the enclosure interior. An evaporator located at the enclosure interior is positioned so that at least some of the air that passes through the enclosure opening flows in a direct and uninterrupted path to the evaporator. A shield within the enclosure interior is interposed between the enclosure opening and the evaporator and is positioned so as to deflect at least a part of the air flowing from that direct and uninterrupted path. The shield provides a site at which moisture contained within at least some of the air passing through the enclosure opening can collect. The enclosure can comprise the freezer compartment of a refrigerator, and the enclosure opening can be in fluid communication with an interior of a fresh food compartment of the refrigerator.

Abstract: Embodiments of the present disclosure include a pig ramp for receiving and supporting a pig in a pig receiver includes a frame portion having an inner diameter, the inner diameter of the ring being larger than an outer diameter of a pig. The pig ramp also includes one or more ramp segments extending longitudinally away from the frame portion, the one or more ramp segments being coupled to a back side of the frame portion at a lower portion and positioned to receive and support the pig when positioned thereon to elevate the pig above a bottom of a tubular.

Abstract: A hydrostatic transmission for a working machine having a frame, an engine on the frame, and at least one wheel driven by the hydrostatic transmission is disclosed. The hydrostatic transmission includes a housing, a hydraulic pump, the hydraulic pump driven by an output shaft from the engine, a hydraulic motor for driving an output shaft connected to the at least one wheel, a first fluid line fillable with hydraulic fluid to be maintained under a first pressure, a second fluid line fillable with hydraulic fluid to be maintained under a second pressure, a first check valve for allowing hydraulic fluid to enter the first fluid line, a second check valve for allowing hydraulic fluid to enter the second fluid line, and an entrained air deflector for preventing hydraulic fluid entrained with air from entering the first check valve and the second check valve.

Abstract: Technology is described for a relative timed clock gated cell. In one example, the relative timed clock gated cell includes a trigger latch and a data clock latch. The trigger latch includes a clock input coupled to a trigger line for transmitting a trigger signal. The trigger latch is configured to generate a data clock signal on an output. The trigger signal is based on a clock signal. The data clock latch includes a clock input coupled to the output of the trigger latch that latches a data input of the data clock latch based on the data clock signal. Various other computing circuitries and methods are also disclosed.

Abstract: A face mask assembly (FMA) for supplying breathable gas to a wearer. The face mask assembly (FMA) includes a mask frame including a support, a facial cushion attached to the mask frame, and a forehead support. The forehead support includes a forehead cushion assembly and an adjustment knob operatively coupled to the forehead cushion assembly. The adjustment knob is threadably engaged with the forehead cushion assembly such that turning movement of the adjustment knob causes the mask frame to be moved between retracted and extended positions with respect to the forehead cushion assembly.

Abstract: Systems, methods, apparatuses, and software for graphics processing systems in computing environments are provided herein. In one example, a method of handling tiled resources in graphics processing environments is presented. The method includes establishing, in a graphics processing unit, a residency map having values determined from memory residency properties of a texture resource, and sampling from the residency map at a specified location to determine a residency map sample for the texture resource at the specified location, where the residency map sample indicates at least an initial level of detail presently resident and a smoothing component to reach a next level of detail.

Abstract: The subject disclosure relates to deploying segments of global and local message content to form several distinct email messages for transmission in a single send instance. In an example, a method comprises assigning, by a system operatively coupled to a processor, a set of tag data to a set of content data within a message, wherein a first subset of tag data is assigned to a first subset of content data and a second subset of tag data is assigned to a second subset of content data. In another aspect, the system comprises transmitting, by the system, the first subset of content data to a first device based on the first subset of tag data and the second subset of content data to a second device based on the second subset of tag data.

Abstract: Embodiments of the present disclosure include a pig ramp for receiving and supporting a pig in a pig receiver includes a frame portion having an inner diameter, the inner diameter of the ring being larger than an outer diameter of a pig. The pig ramp also includes one or more ramp segments extending longitudinally away from the frame portion, the one or more ramp segments being coupled to a back side of the frame portion at a lower portion and positioned to receive and support the pig when positioned thereon to elevate the pig above a bottom of a tubular.

Abstract: Compositions are provided herein comprising a base polymer having engrafted with a secondary polymeric matrix having hydrophilic and lubricious copolymer brushes. Each copolymer brush further comprises functional groups immobilized along the surface of the brush in a plurality of layers, the functional groups conferring hydrophilic and lubricious properties to the base polymer. These polymer compositions are useful for e.g., fabricating devices for delivery of intraocular lenses (IOLs) as well as improving the hydrophilic properties of contact lenses.

Abstract: Embodiments of the present disclosure include a pig ramp for receiving and supporting a pig in a pig receiver includes a frame portion having an inner diameter, the inner diameter of the ring being larger than an outer diameter of a pig. The pig ramp also includes one or more ramp segments extending longitudinally away from the frame portion, the one or more ramp segments being coupled to a back side of the frame portion at a lower portion and positioned to receive and support the pig when positioned thereon to elevate the pig above a bottom of a tubular.

Abstract: Compositions are provided herein comprising a base polymer having engrafted with a secondary polymeric matrix having hydrophilic and lubricious copolymer brushes. Each copolymer brush further comprises functional groups immobilized along the surface of the brush in a plurality of layers, the functional groups conferring hydrophilic and lubricious properties to the base polymer. These polymer compositions are useful for e.g., fabricating devices for delivery of intraocular lenses (IOLs) as well as improving the hydrophilic properties of contact lenses.

Abstract: Compositions are provided herein comprising a base polymer having engrafted with a secondary polymeric matrix having hydrophilic and lubricious copolymer brushes. Each copolymer brush further comprises functional groups immobilized along the surface of the brush in a plurality of layers, the functional groups conferring hydrophilic and lubricious properties to the base polymer. These polymer compositions are useful for e.g., fabricating devices for delivery of intraocular lenses (IOLs) as well as improving the hydrophilic properties of contact lenses.