Abstract: Provided are novel biocompatible copolymers and compositions comprising the copolymers. The copolymers are non-toxic and typically have an LCST below 37° C. Compositions comprising the copolymers can be used for wound treatment, as a cellular growth matrix or niche and for injection into cardiac tissue to repair and mechanically support damaged tissue. The copolymers comprise numerous ester linkages so that the copolymers are erodeable in situ. Degradation products of the copolymers are soluble and non-toxic. The copolymers can be amine-reactive so that they can conjugate with proteins, such as collagen. Active ingredients, such as drugs, can be incorporated into compositions comprising the copolymers.

Abstract: A cartridge device is provided for applying a fiber matrix to a tubular member such as a saphenous vein graft. The cartridge includes a housing, a tubular member holder, a rotational drive, and a polymer delivery assembly. The housing defines a chamber which surrounds the tubular member holder. The rotational drive rotates the tubular member during the fiber application process.

Abstract: A system for electrospinning a fiber matrix on a tubular member includes at least one nozzle, a tubular member in a spaced relationship to the at least one nozzle, and a fluid source for pressurizing a lumen of the tubular member. An electrical potential is applied between the at least one nozzle and either the tubular member or fluid from the fluid source. The electrical potential draws at least one fiber from the at least one nozzle to the tubular member.

Abstract: A biohybrid scaffold is provided that is useful in clinical applications for abdominal wall reconstruction, pelvic floor repair, breast reconstruction, as well as other soft tissue repairs. Methods of making and using the biohybrid scaffold are provided.

Abstract: Provided herein is a biohybrid elastomeric scaffold comprising a synthetic polymeric component and a biological polymeric component. The scaffold can be fabricated to have many different forms, non-limiting examples of which include a non-woven fibrous mesh or in a porous composite. Methods of use of the biohybrid elastomeric scaffolds in wound healing and tissue regeneration are also provided.

Abstract: Provided herein is a method of making an aligned ECM scaffold useful in refractive correction of the eye and repair of the cornea. Methods of use of the scaffold as well as a scaffold construct are provided.

Abstract: Provided are novel biocompatible copolymers and compositions comprising the copolymers. The copolymers are non-toxic and typically have an LCST below 37° C. Compositions comprising the copolymers can be used for wound treatment, as a cellular growth matrix or niche and for injection into cardiac tissue to repair and mechanically support damaged tissue. The copolymers comprise numerous ester linkages so that the copolymers are erodeable in situ. Degradation products of the copolymers are soluble and non-toxic. The copolymers can be amine-reactive so that they can conjugate with proteins, such as collagen. Active ingredients, such as drugs, can be incorporated into compositions comprising the copolymers.

Abstract: A fluid ejection cartridge for a fluid ejection device includes a print head, having a plurality of fluid ejection nozzles, a fluid reservoir, configured to hold a fluid to be ejected from the print head, and a selectively breachable isolator mechanism, separating the fluid reservoir and the print head.

Abstract: Provided are tubular structures of a biocompatible, triggerably-dissolvable material such as cellulose or a copolymer having an LCST below physiological temperatures. The structures may be embedded within a cell growth scaffold. The tubular structures are useful in growing 3-dimensional tissue structures because nutrients, cytokines or other cell growth and/or differentiation compounds, as well as drugs, such as antibiotics and steroids, can be administered over time, and the tubular structures can be dissolved non-invasively.

Abstract: A lamp assembly including an integral reflector and heat sink having a reflector portion comprising an integrated heat sink and a plurality of integral cooling fins connected to the integrated heat sink, a cathode assembly mechanically coupled to the reflector portion, an anode mechanically coupled to the reflector portion and electrically isolated from the cathode assembly, and at least one thermal stress reduction feature.

Abstract: A projection kiosk for a multi-projector digital signage system includes an enclosure and a frame disposed therein. The frame includes attachment points which can hold in position a plurality of projectors. The projectors may be aligned with sub-pixel-resolution accuracy to enable projection of pixel-aligned images onto a screen. The enclosure includes a heat ducting subsystem configured to direct air into the enclosure, duct air through the projectors, and discharge air away from a projection path between the plurality of projectors and the screen.

Abstract: A light source module includes a lamp assembly having an integrated reflector and heat sink, the lamp assembly having a pressurized gas contained therein, an anode sealingly coupled to the integrated reflector and heat sink, and a cathode sealingly coupled to the integrated reflector and heat sink; and a projector protection system including at least one first projection feature for suspending current flow from the cathode to the anode when at least one first threshold is exceeded and at least one second projector protection feature for stopping the current flow when at least one second threshold is exceeded.

Abstract: Provided herein is a biohybrid elastomeric scaffold comprising a synthetic polymeric component and a biological polymeric component. The scaffold can be fabricated to have many different forms, non-limiting examples of which include a non-woven fibrous mesh or in a porous composite. Methods of use of the biohybrid elastomeric scaffolds in wound healing and tissue regeneration are also provided.

Abstract: A tubular tissue graft device is provided comprising a tubular tissue and a restrictive fiber matrix of a bioerodible polymer about a circumference of the tubular tissue. The matrix may be electrospun onto the tubular tissue. In one embodiment, the tubular tissue is from a vein, such as a saphenous vein, useful as an arterial graft, for example and without limitation, in a coronary artery bypass procedure. Also provided is method of preparing a tubular graft comprising depositing a fiber matrix of a bioerodible polymer about a perimeter of a tubular tissue to produce a tubular tissue graft device. A cardiac bypass method comprising bypassing a coronary artery with a tubular tissue graft device comprising a vein and a restrictive fiber matrix of a bioerodible polymer about a circumference of the vein also is provided.

Abstract: A light modulator assembly includes a substrate, a micro-electro mechanical semiconductor device (MEMS device) formed on the substrate, and a temperature control device coupled to the substrate and configured to maintain the MEMS device at or above an elevated threshold temperature.

Abstract: A near net tooth shaped ceramic prosthesis is provided in a tooth shape to minimize the amount of cutting and baking required to finish the outer crown portion of the dental prosthesis. A metallic core is provided for attachment to an implant in a patient's mouth. A ceramic crown is then attached to the core.

Abstract: A dental abutment having a metallic core, a shield surrounding an outer surface of the core, and a polymeric cuff surrounding the core and shield, wherein the cuff bonds to a polymeric prosthesis.

Abstract: A near net tooth shaped ceramic prosthesis is provided in a tooth shape to minimize the amount of cutting and baking required to finish the outer crown portion of the dental prosthesis. A metallic core is provided for attachment to an implant in a patient's mouth. A ceramic crown is then attached to the core.

Abstract: A dental implant includes a body having a coronal end, and an apical end opposite the coronal end. An implant-prosthetic interface region is provided adjacent the coronal end. A tapered region is adjacent the apical end. A variable profile helical thread extends along the tapered region. The thread includes an apical side, a coronal side and a width defined between the apical and coronal sides. The variable profile thread includes an expanding width in the direction of the coronal end.

Abstract: A dental abutment having a metallic core, a shield surrounding an outer surface of the core, and a polymeric cuff surrounding the core and shield, wherein the cuff bonds to a polymeric prosthesis.