Abstract: A pacemaker system includes a drive-sense circuit (DSC) operably coupled to a pacemaker lead. The DSC generates a pace signal including electrical impulses based on a reference signal. The DSC provides the pace signal via the pacemaker lead to an electrically responsive portion of a cardiac conductive system of a subject to facilitate cardiac operation of a cardiovascular system of the subject. The DSC senses, via the pacemaker lead, cardiac electrical activity of the cardiovascular system of the subject that is generated in response to the pace signal and electrically coupled into the pacemaker lead and generates a digital signal that is representative of the cardiac electrical activity of the cardiovascular system of the subject that is sensed via the pacemaker lead. The DSC provides digital information to one or more processing modules that includes and/or is coupled to memory and that provide the reference signal to the DSC.

Abstract: An electronic device can include a housing component at least partially defining an internal volume and including a wall. A component can be disposed within the wall and at least partially surrounded by a material forming the housing. A battery can be disposed in the internal volume and electrically connected to the component.

Abstract: Systems and methods for tracking the location of a non-destructive inspection (NDI) scanner using scan data converted into images of a target object. Scan images are formed by aggregating successive scan strips acquired using one or two one-dimensional sensor arrays. An image processor computes a change in location of the NDI scanner relative to a previous location based on the respective positions of common features in partially overlapping scan images. The performance of the NDI scanner tracking system is enhanced by: (1) using depth and intensity filtering of the scan image data to differentiate features for improved landmark identification during real-time motion control; and (2) applying a loop-closure technique using scan image data to correct for drift in computed location. The enhancements are used to improve localization, which enables better motion control and coordinate accuracy for NDI scan data.

Abstract: The present disclosure relates to compounds of Formula I: and pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof, useful in the treatment of treating viral infections, for example, coronaviridae infections.

Abstract: There are disclosed novel anti-ROR1 macrocyclic peptides and their conjugates with general structure of formula (I), which can be used as ROR1 inhibitors.

Abstract: A collection system for collecting outflow from a hysteroscopic surgical procedure includes a plurality of collection vessels each including a flexible body defining an internal volume and transitionable between a collapsed configuration and an expanded configuration. The collection system further includes connection tubing coupling adjacent collection vessels with one another, outflow tubing coupled to at least one of the collection vessels, and a plurality of retention canisters. Each retention canister includes a rigid body. Each collection vessel is configured to engage a corresponding retention canister such that each rigid body at least partially receives one of the flexible bodies therein.

Abstract: Method and system for flash recycling of batteries, including lithium-ion batteries, other metal (sodium, potassium, zinc, magnesium, and aluminum)-ion batteries, metal batteries, batteries having all metal oxide cathodes, and batteries having graphite-containing anodes. The method and system include a solvent-free and water-free flash Joule heating (FJH) method performed upon a mixture that includes materials from the batteries done in millisecond for recycling the materials. In some embodiments, the FJH method is combined with magnetic separation to recover lithium, cobalt, nickel, and manganese with high yields up to 98%. In some embodiments, the FJH method is followed by rinsing with dilute acid, such a 0.01 M HCl. In other embodiments, the FJH method is utilized to purify the graphite in the battery, such as for use in the anode of the battery.

Abstract: Disclosed herein are peptides with antimicrobial, antiviral, antifungal or antitumor activity when administered to a subject. Also disclosed herein are methods that can be used for treating or preventing a condition or disease in a human subject in need thereof comprising intravenously administering a pharmaceutical composition to said human subject over an extended period of time.

Abstract: A process for hydrotreating a feed stream comprising a biorenewable feedstock is disclosed. The process comprises hydrotreating the feed stream in the presence of a hydrotreating hydrogen stream and a hydrotreating catalyst to provide a hydrotreated stream. The hydrotreated stream is separated into a hydrotreated liquid stream and a hydrotreated gas stream. The hydrotreated liquid stream is subjected to stripping to provide a stripper off-gas stream. At least a portion of the stripper off-gas stream is contacted with a caustic stream to provide a sulfur-lean gas stream and a sulfur-rich caustic stream. The sulfur-rich caustic stream is further treated to provide a treated gas stream.

Abstract: The present invention provides crystalline solids of 6?-((6-aminopyrimidin-4-yl)amino)-8?-methyl-2?H-spiro[cyclohexane-1,3?-imidazo[1,5-a]pyridine]-1?,5?-dione: The crystalline compounds of the present application are inhibitors of Mnk and finds utility in any number of therapeutic applications, including but not limited to treatment of inflammation and various cancers.

Abstract: Systems and methods are disclosed whereby a surface detection system is employed to obtain intraoperative surface data characterizing an exposed surface of the spine. In some embodiments, this intraoperative surface data is registered to segmented surface data obtained from volumetric data of the spine in order to assess the intraoperative orientation of the spine and provide feedback associated with the intraoperative orientation of the spine. The feedback may characterize the intraoperative spinal orientation as a change relative to the preoperative orientation.

Abstract: Compounds of Formulae I, II or III, and pharmaceutically acceptable salts thereof, are useful as CDK inhibitors.

Abstract: A series of piperidine-substituted benzoic acid compounds and the use thereof, and specifically disclosed is a compound represented by formula (I) and a pharmaceutically acceptable salt thereof.

Abstract: The invention relates to novel methods and compositions for conferring tolerance to glyphosate to plants. The invention also provides glyphosate-tolerant plants, seeds, tissue, cells, and plant parts comprising modified EPSP synthases and recombinant DNA molecules encoding modified EPSP synthases, as well as methods of producing the same and the use thereof.

Abstract: Described herein are methods of forming a VOC and odor-reducing building panel. The methods include providing a substrate; applying a wet-state coating to a major surface of the substrate, the wet-state coating comprising carrier comprising water; and drying the wet-state coating, thereby evaporating at least 95 wt. % of the carrier to form a dry-state coating.

Abstract: An electronic device can include a housing defining an aperture and a display positioned in the aperture. The display and the housing can define an internal volume in which a speaker assembly is positioned. The speaker assembly can include a speaker module and a speaker enclosure in fluid communication, with the speaker enclosure at least partially defining a speaker volume.

Abstract: Systems and methods are provided in which an intraoperative video feed is augmented with one or more virtual display features based on a detected orientation and position of the tracked medical instrument. In some example embodiments, the virtual display features may be employed to represent, in an augmented video feed, information associated with a previously-detected intraoperative position and orientation of the tracked medical instrument. The virtual display element may be employed, for example, to facilitate the alignment of an untracked medical instrument with a previously determined intraoperative position and orientation of the tracked medical instrument. In other example embodiments, the virtual display element may be dynamically displayed in a fixed spatial relationship relative to the tracked medical instrument.

Abstract: A superconductor junction includes a normal metal layer having a first side and a second side, an insulating layer overlying the second side of the normal metal layer, and a first superconductor layer formed of a first superconductor material that overlies a side of the insulating layer opposite the side that overlies the normal metal layer. The superconductor junction further includes a second superconductor layer formed of a second superconductor material with a first side overlying a side of the first superconductor material opposite the side that overlies the insulating layer. The second superconductor material has a higher diffusion coefficient than the first superconductor material and/or the second superconductor material has a lower recombination coefficient than the first superconductor metal layer. A normal metal layer quasiparticle trap is coupled to a second side of the second superconductor layer.

Abstract: A head-mountable display with a light shield that can be modified to reduce the friction against softer more pliable portions of a user's face when the head-mountable display is worn by the user. The head-mountable display can also be configured to capture images of the user's face when it is worn and then create an avatar of the user's face. The avatar can be digitally adjusted to reflect an avatar that more closely aligns with the user's desired configuration.

Abstract: A removable facial interface for a head-mountable device (HMD) is disclosed. In an example, an HMD includes a display; a facial interface frame at least partially surrounding the display; a removable facial interface attached to the facial interface frame; a first attachment mechanism attached to one of the facial interface frame or the removable facial interface; and a second attachment mechanism attached to the other of the facial interface frame or the removable facial interface, the removable facial interface being attached to the facial interface frame by the first attachment mechanism and the second attachment mechanism.