Abstract: Bioinsecticidal compositions and methods of use of the same are provided, which include monoterpenes that target GABA receptor-associated protein.

Abstract: A head-mounted device includes an external facing sensor configured to generate a signal corresponding to a characteristic of an external environment. A controller is configured to determine that a quality of the signal is below a threshold value and take an action in response. Another embodiment includes a case for storing a head-mounted device that includes a cleaner coupled with a base or a lid of case. The cleaner is configured to clean a portion of the head-mounted device when the head-mounted device is inserted into and/or removed from the case.

Abstract: The disclosure describes novel systems, methods, and compositions for the manipulation of nucleic acids in a targeted fashion. The disclosure describes non-naturally occurring, engineered CRISPR systems, components, and methods for targeted modification of nucleic acids. Each system includes one or more protein components and one or more nucleic acid components that together target nucleic acids.

Abstract: A cushion assembly for a wearable electronic device includes a polymer structure and foam. The polymer structure can include a laminar portion defining a first aperture and a second aperture, a first tube structure extending from a peripheral edge of the first aperture, and a second tube structure extending from a peripheral edge of the second aperture. The foam can be disposed between the first tube structure and the second tube structure.

Abstract: Embodiments are directed to a low profile key for a keyboard having an overmolded support structure. In one aspect, an embodiment includes a key cap having an illuminable symbol. A support structure having a pair of overmolded wings may pivotally couple to the key cap. A switch housing may surround the support structure and connect each of the first and second wings. A tactile dome may be at least partially positioned within the switch housing and configured to bias the key cap upward. A sensing membrane may be positioned along an underside surface of the tactile dome and configured to trigger a switch event in response to a collapsing of the tactile dome caused by a depression of the key cap. A feature plate may be positioned below the sensing membrane. A light guide panel may define at least one light extraction feature that may be configured to propagate light toward the key cap and cause illumination of the illuminable symbol.

Abstract: Aspects of the invention include systems and methods configured to prevent masquerading service attacks. A non-limiting example computer-implemented method includes sending, from a first server in a cloud environment, a communication request comprising an application programming interface (API) key and a first server identifier to an identity and access management (IAM) server of the cloud environment. The API key can be uniquely assigned by the IAM server to a first component of the first server. The first server receives a credential that includes a token for the first component and sends the credential to a second server. The second server sends the credential, a second server identifier, and an identifier for a second component of the second server to the IAM server. The second server receives an acknowledgment from the IAM server and sends the acknowledgment to the first server.

Abstract: A computer system receives, by a messaging application, information identifying a first shared content item as shared content. The first shared content item is of a first type. In response to receiving the information identifying the first shared content item as shared content and in accordance with a determination that a first application of the plurality of applications can open content of the first type, in accordance with a determination that providing the information identifying the first shared content item as shared content to the first application has been authorized, computer system device automatically makes the first shared content item available within the first application, and in accordance with a determination that providing information identifying the first shared content item as shared content to the first application has not been authorized, the computer system does not make the first shared content item automatically available within the first application.

Abstract: Glucose monitoring devices and related systems and methods, the glucose monitoring devices including a sensor electronics unit having a housing and a printed circuit board disposed within the housing, a transcutaneous glucose sensor assembly, and a conductive sensor connector. The printed circuit board includes a first electrical contact, the transcutaneous glucose sensor assembly includes a distal portion having a working electrode and proximal portion having a working-electrode contact in electrical communication with the working electrode, and the conductive sensor connector electrically connects the working-electrode contact with the first electrical contact. Further, the conductive sensor connector extends through a hole in the proximal portion of the transcutaneous glucose sensor assembly and through a hole in the printed circuit board.

Abstract: The present application relates to antibodies specifically binding to the V-domain immunoglobulin-containing suppressor of T-cell activation (VISTA) at acidic pH and their use in cancer treatment. In some embodiments, the antibodies bind specifically to human VISTA at acidic pH, but do not significantly bind to human VISTA at neutral or physiological pH.

Abstract: A length adjustable robotic limb comprises a first joint assembly, a second joint assembly, and a structural member extending between the first joint assembly and the second joint assembly, the structural member defining a longitudinal axis. An adjustable interface can be provided between the structural member and one of the first and second joint assemblies. The adjustable interface can facilitate adjustment of a length between the first and second joint assemblies. A rotational interface between the structural member and one of the first and second joint assemblies can facilitate relative rotation between the first joint assembly and the second joint assembly about the longitudinal axis in a degree of freedom corresponding to medial/lateral rotation of a portion of a human limb.

Abstract: Adaptively controlling a speaker assembly allows an acoustic characteristic of the speaker assembly to automatically change based on one or more factors. For example, when external noise is detected, the associated noise volume level is determined, and control instructions are generated based on the noise volume level. The control instructions cause the speaker assembly to adaptively increase the volume level to effectively cancel the noise volume. In another example, when a speaker assembly in a vehicle changes from playing a media file to conducting a phone conversation, the volume level associated with the phone conversation may increase. In this regard, control instructions can be generated and used to adaptively reduce the volume level of the phone conversation.

Abstract: Systems of the present disclosure can provide head-mountable devices with different input and output capabilities. Such differences can lead the head-mountable devices to provide the corresponding users with somewhat different experiences despite operating in a shared environment. However, the outputs provided by one head-mountable device can be indicated on another head-mountable device so that the users are aware of the characteristics of each other's experience. Where different head-mountable devices provide different sensing capabilities, the sensors of one head-mountable device can contribute to the detections of the other to provide more accurate and detailed outputs, such as object recognition, avatar generation, hand and body tracking, and the like.

Abstract: A touch sensor device (TSD) includes TSD electrodes associated with a surface of the TSD. Also, an overlay that includes marker electrode(s) is also associated with a region of the surface of the TSD. The TSD also includes drive-sense circuits (DSCs) operably coupled to the plurality of TSD electrodes. A DSC is configured to provide a TSD electrode signal to a TSD electrode and simultaneously to sense a change of the TSD electrode signal based on a change of impedance of the TSD electrode caused by capacitive coupling between the TSD electrode and the marker electrode(s) of the overlay. Processing module(s) is configured to process a digital signal generated by the DSC and other digital signals generated by other DSCs determine the region of the surface of the TSD that is associated with the overlay and to adapt sensitivity of the TSD within that region.

Abstract: An apparatus can include a head-mountable display, a facial interface, a connector between the head-mountable display and the facial interface, a cushion positioned proximate to the connector, and a wearable strap connected to at least one of the head-mountable display or the facial interface. In one example, the cushion includes an aluminum block with an air pocket. In another example, the cushion includes a foam cushion. In certain implementations, the foam cushion defines a channel, the connector being positioned within the channel. In other implementations, the foam cushion includes a foam torus, the connector being positioned inside a center hole of the foam torus.

Abstract: A system may include an electronic device such as a head-mounted device and a handheld input device for controlling the electronic device. A tracking device may be removably coupled to the handheld input device to increase the precision with which the head-mounted device tracks the handheld input device. The tracking device may have larger dimensions than the handheld input device and/or may have an expandable housing that expands and retracts. Visual markers on the tracking device may include infrared light-emitting diodes, geometric surface features, or other optical tracking features. The tracking device may serve as a secondary input device for the head-mounted device when the tracking device is decoupled from the input device. The tracking device may have a recess for receiving a shaft of the input device and may have magnets or other attachment structures for attaching the tracking device to the input device.

Abstract: The present invention relates to nucleases or nucleic acids encoding the nucleases, RNA guides or nucleic acids encoding the RNA guides, processes for characterizing the nucleases and/or RNA guides, compositions comprising the nucleases and/or RNA guides, and kits and/or methods for preparing and/or using the nucleases and/or RNA guides.

Abstract: Method and system for mapping and/or inspecting an underground pipeline infrastructure, using: a sensor probe for collecting geospatial data while travelling through a pipeline of the pipeline infrastructure, and a driving mechanism comprising a tether, for driving the sensor probe, wherein the sensor probe is provided to enter the pipeline at a vertical angle through a live-fluid entry apparatus and once inside the pipeline make a 90° angle change of direction to align with the orientation of the pipeline.

Abstract: An endoscopic irradiation device for inactivating pathogens is disclosed. The device includes a control element and a probe that is directed by the control element. A source of UVC light providing a peak irradiation of about 222 nm is integrated with at least one of the probes and the control element. An attenuating element attenuates irradiation above about 235 nm is located in a path of UVC light generated by the source of UVC light. The attenuating element is integrated with at least one of said medical probe and said control element. In one embodiment, attenuating element takes the form of a band pass filter placed between the source of UVC light and biological tissue being irradiated by the UVC light. Alternatively, the attenuating element is a dopant disposed within a crystalline structure of a light emitting diode that restricts or attenuates transmission above about 235 nm.

Abstract: A capacitive imaging glove includes electrodes implemented throughout the capacitive imaging glove and drive-sense circuits (DSCs) such that a DSC receives a reference signal generates a signal based thereon. The DSC provides the signal to a first electrode via a single line and simultaneously senses it. Note the signal is coupled from the first electrode to the second electrode via a gap therebetween. The DSC generates a digital signal representative of the electrical characteristic of the first electrode. Processing module(s), when enabled, is/are configured to execute operational instructions (e.g., stored in and/or retrieved from memory) to generate the reference signal, process the digital signal to determine the electrical characteristic of the first electrode, and process the electrical characteristic of the first electrode to determine a distance between the first electrode and the second electrode, and generate capacitive image data representative of a shape of the capacitive imaging glove.

Abstract: Cardiac activity can be mapped by receiving an electrogram, transforming the electrogram into the wavelet domain (e.g., using a continuous wavelet transformation) to create a scalogram of the electrogram, computing at least one energy function of the scalogram, and computing at least one metric of the electrogram using the at least one energy function. The metrics of the electrogram can include, without limitation: a QRS activity duration for the electrogram; a near-field component duration for the electrogram; a far-field component duration for the electrogram; a number of multiple components for the electrogram; a slope of a sharpest component of the electrogram; a scalogram width; an energy ratio in the electrogram; and a cycle-length based metric of the electrogram.