Abstract: A handheld light assembly for eradicating pathogens includes a housing. A processor and a lamp are disposed inside the housing. The lamp irradiates surfaces with disinfecting ultraviolet light having a peak wavelength of 222 nm filtered to restrict illumination to between 200 nm and 230 nm within an irradiation zone. A distance measuring system includes a secondary light source generating secondary light and a photodetector for measuring distance of the secondary light to a surface being irradiated by the lamp light being reflected from the surface to the photodetector. The secondary light source is offset at an angle from the lamp thereby projecting the light beam to a central area of the irradiation zone generated by the lamp. The photodetector signals the processor to calculate a vertical distance between the lamp and the central area of the irradiation zone on the surface being irradiated from an angular projection of the secondary light.

Abstract: In some embodiments, an electronic device displays a virtual keyboard, wherein the virtual keyboard includes a plurality of selectable representations of a plurality of graphical objects. In some embodiments, the electronic device receives a user input selecting a first selectable representation of a first graphical object, wherein the first graphical object is associated with a first customizable visual element and a second customizable visual element. In some embodiments, in response to receiving the user input and in accordance with a determination that one or more first criteria are satisfied, the electronic device displays, via the display device, a customization user interface, including a first section for customizing the first customizable visual element, a second section for customizing the second customizable visual element, and a third section for displaying a first respective representation of the first graphical object that indicates a current state of customization of the first graphical object.

Abstract: A microcatheter with an enhanced inner liner that has low of friction and improved toughness which facilitates delivery of expandable vascular reconstruction devices.

Abstract: A method for operating a robotic joint of a robotic system comprising selectively operating a clutch mechanism of a clutched joint module in an engaged state to cause a quasi-passive elastic actuator to enter an elastic state, the clutched joint module operating about and defining a joint of the robotic system. The method comprising effecting a first rotation of the joint to cause the quasi-passive elastic actuator to store energy during at least a portion of the rotation of the joint. The method comprising effecting a second rotation of the joint and causing the stored energy from the quasi-passive elastic actuator to be released in the form of an augmented torque applied to an output member of the clutched joint module. The method comprising selectively operating the clutch mechanism in a disengaged state to cause the quasi-passive elastic actuator to enter an inelastic state.

Abstract: A surgical planning and assessment system is disclosed. The system may include a computing system having a processor, a data store, and a patient specific planning and analysis module. The system may be configured to store a patient specific target plan including a digital representation of a spinal rod having a target geometry and transform the digital representation into a curved line. The system may generate a spline data set comprising a plurality of spline segments that are sequentially linked to one another. The system may adjust, iteratively, each spline segment until the plurality of spline segments approximate the curved line. The system may generate a digital file comprising drawings for manufacturing a spinal rod based on the plurality of spline segments. In various embodiments, each spline segment may be defined by a corresponding arc or a corresponding line extending between a corresponding starting point and a corresponding ending point.

Abstract: Some demonstrative embodiments include devices, systems and/or methods of simultaneously communicating with a group of wireless communication devices. For example, a device may include a wireless communication unit to communicate with at least one group of a plurality of wireless communication devices over a wireless communication medium, wherein the wireless communication unit is to reserve the wireless communication medium for a time period, during which the wireless communication unit is to simultaneously transmit two or more different wireless communication transmissions to two or more wireless communication devices of the group, respectively. Other embodiments are described and claimed.

Abstract: Low-profile computer supports include features to reduce the thickness and improve the portability or storage capability of a computer system while it is disassembled, packaged, shipped, or moved. Some computer systems have a computing device and a dock device that can be stored and moved separately or that can store or support accessories associated with the computer system. Some computer systems have a movable stand configured to transition between a collapsed state and a deployed or standing state. Some stands include handles or grips for moving the computer systems while collapsed. Other computer systems include handles or grips to provide areas to more easily carry the computer systems. The handles or grips can have features such as a flexible material to hide or mask their appearance on the computer system.

Abstract: One or more computing devices, systems, and/or methods for identifying anomalous behavior of users are provided. In an example, users of a telecommunication service provider may be segmented into a plurality of user segments based upon telecommunication service metrics associated with the users. A machine learning model may be trained using telecommunication service information associated with users of the first user segment to generate a trained machine learning model. Using the trained machine learning model, a forecast of telecommunication service usage associated with a first user segment of the plurality of user segments. A telecommunication service usage metric, associated with a user belonging to the first user segment, may be compared with a range indicated by the forecast. The user may be flagged as having anomalous behavior based upon a determination that one or more telecommunication usage metrics, associated with the user, are outside one or more ranges indicated by the forecast.

Abstract: Disclosed herein are antibodies useful that bind to connexin 43 hemichannels to inhibit or block channel opening. Also disclosed herein are methods for detecting or treating osteoarthritis, rheumatoid arthritis, and tendon disorders and injuries with antibodies that inhibit or block Cx43 hemichannel opening.

Abstract: An airfoil includes an airfoil wall that has a wishbone-shaped fiber layup structure. The structure includes two arms that merge into a single leg. The single leg includes fiber tows from each of the arms that are interwoven. The single leg forms at least a portion of the trailing edge of the airfoil wall. Each of the arms includes a first section that is distal from the single leg and a second section that is proximal to the single leg. The first section defines a first thickness, the second section defines a second thickness that is greater than the first thickness, and the single leg defines a third thickness that is greater than the second thickness.

Abstract: A technology is described for redundant network communication in a robot. An example of the technology can include a main robotic controller and a robotic component including a local controller and a controlled component that is operable based on a data signal comprising control instructions executed by the local controller. A command can be sent between the main robotic controller and the local controller. The command can be encoded in a first data signal and a second data signal. The first data signal can be sent over a first network channel, and the second data signal can be sent over a second network channel. The first data signal and the second data signal can be configured to be redundant data signals for the local controller sent respectively over the first network channel and the second network channel.

Abstract: The present application relates to pharmaceutical formulations and dosage forms of an AXL/MER inhibitor, or a pharmaceutically acceptable salt, solvate, or hydrate thereof, including methods of preparation thereof, which are useful in the treatment of AXL/MER mediated diseases such as cancer.

Abstract: A method of identifying methylated cell-free DNA (cfDNA) biomarkers is provided, referred to as layered analysis of methylated biomarkers (LAMB). In particular, the LAMB methodology can be used to analyze data from patients to discover methylated cfDNA biomarkers associated with cancer. LAMB was used to identify tumor suppressor candidates using meta-analysis of cancer tissue methylation studies, followed by screening for tumor-specific promoter CpGs in these tumor suppressors and analysis of microarray data for cancerous tissues, non-cancerous tissues adjacent to tumors, and healthy blood samples. Biomarker panels for diagnosis of liver, colorectal, prostate, and lung cancer as well as biomarkers for predicting tumor response to therapy are provided based on this LAMB methodology. The biomarkers identified by LAMB can be used alone or in combination with one or more additional biomarkers or relevant clinical parameters in prognosis, diagnosis, therapy selection, or monitoring treatment of cancer.

Abstract: A head-mounted device may include a main housing portion and displays in the main housing portion that provide images to eye boxes. A light seal may be coupled to the main housing portion and may at least partially surround the eye boxes. The head-mounted device may include sweat mitigation structures such as moisture-guiding channels in the light seal to guide sweat and other moisture away from the eye boxes. The moisture-guiding channels may be formed from grooves or moisture-wicking fabric. Control circuitry may adjust a fan based on humidity, temperature, or fog detected by a sensor. The light seal may include a directional pattern of grooves through which moisture is guided away from the eye boxes. A moisture barrier layer may be interposed between an inner foam layer and an outer light-blocking fabric to prevent sweat from penetrating into the foam.

Abstract: A method of forming a FinFET is disclosed. The method includes depositing a conductive material across each of a number of adjacent fins, depositing a sacrificial mask over the conductive material, patterning the conductive material with the sacrificial mask to form a plurality of conductive material segments, depositing a sacrificial layer over the sacrificial mask, and patterning the sacrificial layer, where a portion of the patterned sacrificial layer remains over the sacrificial mask, where a portion of the sacrificial mask is exposed, and where the exposed portion of the sacrificial mask extends across each of the adjacent fins. The method also includes removing the portion of the sacrificial layer over the sacrificial mask, after removing the portion of the sacrificial layer over the sacrificial mask, removing the sacrificial mask, epitaxially growing a plurality of source/drain regions from the semiconductor substrate, and electrically connecting the source/drain regions to other devices.

Abstract: A system may include an electronic device such as a head-mounted device and a handheld controller for controlling the electronic device. The handheld controller may have a housing with an elongated shaft extending between first and second tip portions. The handheld controller may have power receiving circuitry configured to receive power from a power source. The power source may be incorporated into an electronic device such as a wireless charging dock or stick, a battery case, or a head-mounted device. The power source may supply power through terminals that form ohmic contacts with mating terminals in the finger device or may transmit power wirelessly using capacitive coupling or inductive charging arrangements. Magnets may be used to hold and align the elongated shaft of the handheld controller on the power source.

Abstract: Devices, systems, methods, and computer program products for performing a medical procedure are disclosed herein. In some embodiments, a system for performing a medical procedure in an anatomic region includes a medical instrument configured to be inserted within the anatomic region, the medical instrument including an image capture device. The system can also include a positional sensor associated with the medical instrument. The system can be configured to receive a model of the anatomic region. The system can obtain image data from the image capture device and a set of coordinate points from the positional sensor. The system can generate a registration between the model and the anatomic region based on the image data and the coordinate points.

Abstract: A rotary shaft assembly includes a rotary shaft having a first end portion, a second end portion opposite the first end portion, a longitudinal axis extending centrally through the first and second end portions, and a shaft body that defines a bore between the first and second end portions. An anti-flailing mechanism is positioned within the bore of the shaft body. The anti-flailing mechanism is coupled to rotary shaft and extends at least partially between the first and second end portions to contain the rotary shaft about the longitudinal axis when the rotary shaft fails.

Abstract: An electronic device may include a glass housing member that includes an upper portion defining a display area, a lower portion defining an input area, and a transition portion joining the upper portion and the lower portion and defining a continuous, curved surface between the upper portion and the lower portion. The electronic device may include a display coupled to the glass housing member and configured to provide a visual output at the display area. The electronic device may include an input device coupled to the glass housing member and configured to detect inputs at the input area. The electronic device may include a support structure coupled to the glass housing member and configured to support the computing device.

Abstract: The disclosure describes novel systems, methods, and compositions for the manipulation of nucleic acids in a targeted fashion. The disclosure describes non-naturally occurring, engineered CRISPR systems, components, and methods for targeted modification of nucleic acids such as DNA. Each system includes one or more protein components and one or more nucleic acid components that together target nucleic acids.