Patents by Inventor Xian Zhang

Xian Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10623837
    Abstract: This application provides a node device implementing connection establishment for a Space Division Multiplexing (SDM) network. A first node receives a path (Path) message, which includes a plurality of label objects, each label object includes a field used to indicate a number of an optical core in a multi-core optical fiber, and idle spectrum information of each optical core. The first node then obtains an intersection set of the idle spectrum information of each optical core indicated in the path message and idle spectrum information of a corresponding optical core on a first link. The first node sends, over the first link, a path message that carries an intersection set result, where the first link is a link between the first node and an adjacent node in a direction from the first node to an end node.
    Type: Grant
    Filed: June 13, 2019
    Date of Patent: April 14, 2020
    Assignee: HUAWEI TECHNOLOGIES CO., LTD.
    Inventors: Zhijiang Gao, Xian Zhang
  • Patent number: 10612054
    Abstract: The present invention discloses a single-cell factory for efficiently synthesizing ?-aminobutyric acid and construction and application thereof, which belong to the technical field of microorganisms. The present invention expresses an L-threonine deaminase gene, an L-amino acid dehydrogenase gene and a dehydrogenase gene for providing cofactor NADH cycle in tandem to construct a recombinant Escherichia coli single-cell factory which is used for efficiently synthesizing ?-aminobutyric acid. The expression level of the L-threonine deaminase is optimized and controlled by an RBS sequence, so that the problem of transformation inhibition caused by the rapid accumulation of an intermediate product ketobutyric acid is solved, moreover, the expression level of the dehydrogenase for providing cofactor NADH cycle is optimized and controlled by a promoter and an RBS sequence, consequently, the NADH regeneration rate is increased, and ultimately, yield is increased.
    Type: Grant
    Filed: November 17, 2016
    Date of Patent: April 7, 2020
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Zhiming Rao, Junping Zhou, Taowei Yang, Xian Zhang, Meijuan Xu, CaiZhe Zhang, Yunlong Qi, Junxian Zheng
  • Publication number: 20200084263
    Abstract: It involves the field of power trading technology and a method for microservice transformation of power trading function comprising the following steps: (1) divide the function in extranet trading cloud into many multiple individual micro services and divide the function in intranet trading cloud into multiple individual micro services; (2) register a node information for each individual micro service in service registry when service deployment starts; (3) extranet users and intranet users enter into extranet trading cloud and intranet trading cloud respectively through PC terminal or mobile terminal, obtain the actual network address that needs to be served from service registry, send a request to the requested service, and perform related business operation.
    Type: Application
    Filed: December 22, 2017
    Publication date: March 12, 2020
    Inventors: LIN CHENG, HAINING WANG, XIAN ZHANG, CHUNCHENG GAO, YONGHUI LIU, YIN FANG, SHUHONG SHI, YONG DAI, LI TAO, CHUNYAN WANG, MINGZHU YUAN, LEI WANG, TAO WANG, JIE LIU, XIAN ZHAO, XIANG TAN, NING YANG, SHOUBAO LI, PEIYU XI, QIAN ZHANG, DONG LIU, WUJUN DONG, WENTAO LV, SHULU WAN, WEI WANG, XIAOPENG YUAN, JUNLIANG LV, LIN ZHANG, XIN CHANG, YUJIAN WU
  • Publication number: 20200081898
    Abstract: The invention involves the field of power trading and especially involves a method for construction of power trading index system based on big data technology. Main steps are as follows: 1. data acquisition; 2. construction of index system: construction of index system is mainly based on cloud focus evaluation method to solve the problem of variables transformation and make data analysis through high concurrency distributed computing power of Spark memory access; 3. index calculation: adopt objective weighting approach to determine the weight of each index after index configuration and then adopt cloud focus evaluation method to calculate the weighted deviation of each index; store final evaluation result of each index into HDFS database after Spark calculation; 4. index display.
    Type: Application
    Filed: December 22, 2017
    Publication date: March 12, 2020
    Inventors: HAINING WANG, LIN CHENG, YONGHUI LIU, SHUHONG SHI, XIAN ZHANG, CHUNCHENG GAO, YIN FANG, YONG DAI, LI TAO, MINGZHU YUAN, LEI WANG, TAO WANG, JIE LIU, XIAN ZHAO, XIANG TAN, NING YANG, SHOUBAO LI, PEIYU XI, QIAN ZHANG, CHUNYAN WANG, DONG LIU, WUJUN DONG, WENTAO LV, SHULU WAN, WEI WANG, XIAOPENG YUAN, JUNLIANG LV, LIN ZHANG, XIN CHANG, YUJIAN WU
  • Patent number: 10566856
    Abstract: The present invention discloses an alternating current (AC) permanent magnet motor, including a stator, a rotor, and a controller. Cable troughs and some same coil windings exist on a silicon steel sheet of a stator core. Grooves exist on the stator core, and stator permanent magnets are mounted in the grooves. The groove includes two types of grooves, namely, open grooves and enclosed grooves, and the two types of grooves are alternately laminated to form the stator core. A coil unit of the stator includes stator permanent magnets mounted in grooves of two stator cores and four same coils, and some same coil units form a three-phase stator coil. The rotor includes rotor cores, enclosed squirrel cages and rotor permanent magnets. The controller outputs a three-phase power source having a same positive and negative half sine-wave or step-wave pulse.
    Type: Grant
    Filed: March 1, 2018
    Date of Patent: February 18, 2020
    Inventor: Xian Zhang
  • Patent number: 10465218
    Abstract: The invention discloses a method for increasing the yield of L-arginine by knocking out flavin reductases, and belongs to the technical field of amino acid production by microbial fermentation. Genes frd1 and frd2 for encoding hypothetic NADPH-dependent FMN reductase in Corynebacterium crenatum SDNN403 are over-expressed in E. coli BL21 and are purified to form target proteins Frd181 and Frd188, and functions of the target proteins are identified to obtain a result showing that the proteins Frd181 and Frd188 both are NAD(P)H-dependent flavin reductases producing H2O2. By taking a genome of the Corynebacterium crenatum SDNN403 as a template, frd1 and frd2 gene deletion fragments are obtained by overlap extension PCR; connecting pK18mobsacB to obtain knockout plasmids pK18mobsacB-?frd1 and pK18mobsacB-?frd2; carrying out electric shock to transform the Corynebacterium crenatum SDNN403; and carrying out secondary screening to obtain recombinant strains 403?frd1 and 403?frd2.
    Type: Grant
    Filed: July 29, 2016
    Date of Patent: November 5, 2019
    Assignee: Jiangnan University
    Inventors: Zhiming Rao, Zaiwei Man, Meijuan Xu, Taowei Yang, Xian Zhang
  • Publication number: 20190306596
    Abstract: This application provides a node device implementing connection establishment for a Space Division Multiplexing (SDM) network. A first node receives a path (Path) message, which includes a plurality of label objects, each label object includes a field used to indicate a number of an optical core in a multi-core optical fiber, and idle spectrum information of each optical core. The first node then obtains an intersection set of the idle spectrum information of each optical core indicated in the path message and idle spectrum information of a corresponding optical core on a first link. The first node sends, over the first link, a path message that carries an intersection set result, where the first link is a link between the first node and an adjacent node in a direction from the first node to an end node.
    Type: Application
    Filed: June 13, 2019
    Publication date: October 3, 2019
    Inventors: Zhijiang GAO, Xian ZHANG
  • Publication number: 20190289477
    Abstract: A link control node and method, and a system are provided. An MPTCP sublink is identified; and from the MPTCP sublink, a first MPTCP sublink on which link control needs to be performed is determined, and an adjustment manner applicable to the first MPTCP sublink is determined. By adding centralized management and control measures on MPTCP connections, a data transmission process on each MPTCP sublink can be performed on an expected communication link, which adapts to running requirements of a system. Therefore, radio resources can be appropriately allocated, and system performance can be improved.
    Type: Application
    Filed: June 7, 2019
    Publication date: September 19, 2019
    Inventors: Min HUANG, Xian ZHANG
  • Patent number: 10358759
    Abstract: The present disclosure discloses a composite balance ring and a washing machine. The balance ring is internally hollow to form a chamber. The chamber is horizontally provided with a partition plate which divides the chamber into upper and lower chambers. The upper and lower chambers communicate through an overflow structure and a backflow structure, and the chamber is filled with balancing liquid with a level close to the partition plate. During the dehydration process of the washing machine, the balancing liquid in the lower chamber overflows into the upper chamber by a low overflow speed through a narrow gap that forms the overflow structure, and the balancing liquid remaining in the lower chamber provided with a counterweight force in the inner tub, so that the increase of eccentric displacement of the inner tub due to eccentric flowing of the balancing liquid is avoided.
    Type: Grant
    Filed: November 14, 2014
    Date of Patent: July 23, 2019
    Assignees: HAIER GROUP CORPORATION, QINGDAO HAIER WASHING MACHINE CO., LTD.
    Inventors: Guosheng Wan, Jingli Yang, Quancheng Feng, Xian Zhang, Changcheng Shao
  • Patent number: 10362496
    Abstract: Embodiments of the present invention provide a link control node and method, and a system. An MPTCP sublink is identified; and from the MPTCP sublink, a first MPTCP sublink on which link control needs to be performed is determined, and an adjustment manner applicable to the first MPTCP sublink is determined. By adding centralized management and control measures on MPTCP connections, a data transmission process on each MPTCP sublink can be performed on an expected communication link, which adapts to running requirements of a system. Therefore, radio resources can be appropriately allocated, and system performance can be improved.
    Type: Grant
    Filed: January 20, 2017
    Date of Patent: July 23, 2019
    Assignee: Huawei Technologies Co., Ltd.
    Inventors: Min Huang, Xian Zhang
  • Patent number: 10351816
    Abstract: The present invention relates to application of a novel signal peptide in L-arginine and its derivatives production from konjac powder, which belongs to the field of gene engineering, enzyme engineering and metabolism engineering. The present invention fused the signal peptide set forth in SEQ ID NO.1 with the ?-mannanase of Bacillus subtilis CCTCC M 209200, and expressed the fused gene in the strain with high L-arginine yield. The recombinant strain Corynebacterium crenatum CGMCC 0890/p MSPman had advantages on utilizing cheaper konjac powder as substrate, and after fermenting for 96 hours in a 5 L bioreactor, the L-arginine yield reached 45 g/L. Another two recombinant strains were constructed based on Corynebacterium crenatum CGMCC 0890/pMSPman, and after fermenting for 96 hours in a 5 L bioreactor, the L-ornithine yield and L-citrulline reached 23.5 g/L and 26.3 g/L respectively.
    Type: Grant
    Filed: November 23, 2015
    Date of Patent: July 16, 2019
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Zhiming Rao, Zhenghong Xu, Junxian Zheng, Meijuan Xu, Taowei Yang, Xian Zhang
  • Publication number: 20190207438
    Abstract: The present invention discloses an alternating current (AC) permanent magnet motor, including a stator, a rotor, and a controller. Cable troughs and some same coil windings exist on a silicon steel sheet of a stator core. Grooves exist on the stator core, and stator permanent magnets are mounted in the grooves. The groove includes two types of grooves, namely, open grooves and enclosed grooves, and the two types of grooves are alternately laminated to form the stator core. A coil unit of the stator includes stator permanent magnets mounted in grooves of two stator cores and four same coils, and some same coil units form a three-phase stator coil. The rotor includes rotor cores, enclosed squirrel cages and rotor permanent magnets. The controller outputs a three-phase power source having a same positive and negative half sine-wave or step-wave pulse.
    Type: Application
    Filed: March 1, 2018
    Publication date: July 4, 2019
    Inventor: Xian ZHANG
  • Publication number: 20190195566
    Abstract: A heat exchanger includes a shell; multiple exchange tubes disposed in multiple layers from the center to the wall of the shell inside the shell; a first board and a second board arranged in parallel inside the shell; and a first spiral gas tube winding in a same direction, the first spiral gas tube having a first wall provided with a plurality of first gas pores, and the first spiral gas tube has a first inlet and a first outlet that respectively communicates with out-source gas. The heat exchanger can carry out online disturbance to the fluid in the shell internally, even in the case that the fluid media are dirty and viscous, the mixing of the fluid media tends to be uniform continuously, thus effectively improving the heat exchange effect, and convenient for cleaning, purging and maintaining the interior of the device.
    Type: Application
    Filed: March 18, 2013
    Publication date: June 27, 2019
    Inventors: Xian'an Zhang, Jianliang Wang, Xingmiao Hu, Lijiang Liu, Lijun Wu
  • Patent number: 10331681
    Abstract: Implementations provide an improved system for presenting search results based on entity associations of the search items. An example method includes, for each of a plurality of crowdsource workers, initiating display of a first randomly selected cluster set from a plurality of cluster sets to the crowdsource worker. Each cluster set represents a different clustering algorithm applied to a set of search items responsive to a query. The method also includes receiving cluster ratings for the first cluster set from the crowdsource worker and calculating a cluster set score for the first cluster set based on the cluster ratings. This is repeated for remaining cluster sets in the plurality of cluster sets. The method also includes storing a cluster set definition for a highest scoring cluster set, associating the cluster set definition with the query, and using the definition to display search items responsive to the query.
    Type: Grant
    Filed: April 11, 2016
    Date of Patent: June 25, 2019
    Assignee: GOOGLE LLC
    Inventors: Jilin Chen, Amy Xian Zhang, Sagar Jain, Lichan Hong, Ed Huai-Hsin Chi
  • Patent number: 10329592
    Abstract: The present invention relates to application of a novel signal peptide in L-glutamate and its derivatives production from konjac powder, which belongs to the field of gene engineering, enzyme engineering and metabolism engineering. The signal peptide which mediated secretion of ?-mannanase was invented, and the recombinant strain with this signal peptide had advantages on utilizing konjac powder to produce related products, and its utilization efficiency of konjac powder, production efficiency, and yield were higher than other signal peptides. The recombinant strain possessing this new signal peptide had advantages on utilizing cheaper konjac powder as substrate to lower the process costs on L-glutamic acid and its high-value-added products.
    Type: Grant
    Filed: November 23, 2015
    Date of Patent: June 25, 2019
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Zhiming Rao, Junxian Zheng, Meijuan Xu, Taowei Yang, Xian Zhang
  • Publication number: 20190185840
    Abstract: The present disclosure discloses a thermophilic L-asparaginase mutant and screening and fermentation methods thereof, and belongs to the field of gene engineering, enzyme engineering and fermentation engineering. In bacillus subtilis 168, a Pyrococcus yayanosii CH1-derived L-asparaginase encoding gene is used as a template, and a mutation library is constructed by an error-prone PCR (epPCR) technology. A mutant strain with improved specific enzyme activity is screened through a high-flux screening method of synchronous cell disruption and enzyme activity measurement. Mutated residues included in a positive mutant are analyzed to construct a composite mutant strain S17G/A90S/R156S/K272A with improved specific enzyme activity and specific enzyme activity of 3108 U/mg. An expression quantity of the composite mutant strain in the bacillus subtilis 168 is increased through measures of a strong promoter P43 and RBS optimization.
    Type: Application
    Filed: January 24, 2019
    Publication date: June 20, 2019
    Inventors: Zhiming Rao, Xu Li, Xian Zhang, Shuqin Xu, Jingyi Hu, Meijuan Xu, Taowei Yang
  • Publication number: 20190185899
    Abstract: The present disclosure discloses a method for producing 9?-hydroxy androstane-4-alkene-3,17-diketone by enzymatic conversion, and belongs to the fields of gene engineering and enzyme engineering. According to the present disclosure, oxidation subunit KshA, reduction subunit KshB and unknown active subunit KshC of 3-ketosteroid-9?-hydroxylase sourcing from Mycobacterium sp. Strain VKM Ac-1817D are successfully expressed in E. coli BL21, and KshC is identified as an oxidation subunit, the enzyme activity of which is far higher than that of KshA. BL21/pET-28a(+)-fdh constructed in the laboratory is used for expressing formate dehydrogenase (FDH), and by using crude enzyme liquid of KSH (KshB+KshC) and FDH engineering bacteria as a biocatalyst and a steroidal compound (AD) as a substrate, optimum reaction temperature is determined as 30° C. and optimum pH is determined as 7.0. In optimum conditions, AD is converted to produce a product 9-OH-AD, and within 20 hours, the output of 9-OH-AD is 4.
    Type: Application
    Filed: January 24, 2019
    Publication date: June 20, 2019
    Inventors: Zhiming Rao, Zongyan Sha, Xian Zhang, Taowei Yang, Meijuan Xu
  • Publication number: 20190161779
    Abstract: The present invention discloses a single-cell factory for efficiently synthesizing ?-aminobutyric acid and construction and application thereof, which belong to the technical field of microorganisms. The present invention expresses an L-threonine deaminase gene, an L-amino acid dehydrogenase gene and a dehydrogenase gene for providing cofactor NADH cycle in tandem to construct a recombinant Escherichia coli single-cell factory which is used for efficiently synthesizing ?-aminobutyric acid. The expression level of the L-threonine deaminase is optimized and controlled by an RBS sequence, so that the problem of transformation inhibition caused by the rapid accumulation of an intermediate product ketobutyric acid is solved, moreover, the expression level of the dehydrogenase for providing cofactor NADH cycle is optimized and controlled by a promoter and an RBS sequence, consequently, the NADH regeneration rate is increased, and ultimately, yield is increased.
    Type: Application
    Filed: November 17, 2016
    Publication date: May 30, 2019
    Inventors: Zhiming RAO, Junping ZHOU, Taowei YANG, Xian ZHANG, Meijuan XU, CaiZhe ZHANG, Yunlong QI, Junxian ZHENG
  • Publication number: 20190161741
    Abstract: The present invention discloses a formate dehydrogenase mutant with improved enzyme activity and stability and a construction method thereof, which belongs to the technical field of genetic engineering. The mutant of the present invention is obtained by mutating alanine at a 10th site to cysteine based on the amino acid shown in SEQ ID NO. 2. The specific enzyme activity of the mutant enzyme obtained by the present invention is improved by 1.3 times compared with that before the mutation, a half-life period (t1/2) at 60° C. is increased by 6.8 times compared with that in the mutation period, the copper ion tolerance is increased by 30 times compared with that before the mutation, and when pH is 4, the stability is improved by 2.0 times, and the catalytic efficiency is increased by 1.4 times.
    Type: Application
    Filed: November 14, 2016
    Publication date: May 30, 2019
    Inventors: Zhiming RAO, Junxian ZHENG, Taowei TAO, Junping ZHOU, Xian ZHANG, Meijuan XU
  • Publication number: 20190153404
    Abstract: The present invention discloses a Mycobacterium neoaurum-derived steroid C27-monooxygenase and an application thereof, which belong to the technical fields of genetic engineering and enzyme engineering. By the method of gene knockout and intensive expression, the present invention screens out three isoenzymes of a key enzyme SMO in the process of degrading sterol side chains from Mycobacterium neoaurum. The three isoenzymes are intensively expressed respectively in the Mycobacterium neoaurum for the high yield of androsta-1,4-diene-3,17-dione (ADD), the yield of ADD is increased remarkably, wherein the effect of SMO2 is most remarkable. By overexpressing SMO2, the final ADD yield is increased from 5.2 g·L.?1 to 7.3 g·L.?1. The present invention provides a helpful guidance for the industrialization of the microbial fermentation method for increasing the ADD yield.
    Type: Application
    Filed: August 29, 2016
    Publication date: May 23, 2019
    Inventors: Zhiming RAO, Minglong SHAO, Xian ZHANG, Taowei YANG, Meijuan XU