Abstract: Embodiments of the present invention provide a network path computation method, apparatus and system, where the method includes: sending, by a first node, a path computation request to a first path computation element PCE, where the path computation request includes a resource sharing object, and a head node and a last node of a first label switched path LSP; and receiving, by the first node, a path computation result that is returned by the first PCE and that is obtained by means of computation according to the resource sharing object, and establishing a second path from the head node to the last node according to the path computation result. According to the network path computation method, apparatus, and system provided in the embodiments of the present invention, link resource utilization can be improved.

Abstract: Use of BUBR1 as a biomarker for predicting the response to a compound, preferably resistance of a disease such as cancer in a subject, wherein the compound is a compound of general formula I wherein R represents phenyl, thienyl or pyridinyl wherein phenyl is optionally substituted by one or two substituents independently selected from alkyl, halo-lower alkyl, hydroxy-lower alkyl, lower alkoxy-lower alkyl, acyloxy-lower alkyl, phenyl, hydroxy, lower alkoxy, hydroxy-lower alkoxy, lower alkoxy-lower alkoxy, phenyl-lower alkoxy, lower alkylcarbonyloxy, amino, monoalkylamino, dialkylamino, lower alkoxycarbonylamino, lower alkylcarbonylamino, substituted amino wherein the two substituents on nitrogen form together with the nitrogen heterocyclyl, lower alkylcarbonyl, carboxy, lower alkoxycarbonyl, cyano, halogen, and nitro; and wherein two adjacent substituents are methylenedioxy; and wherein pyridinyl is optionally substituted by lower alkoxy, amino or halogen; X represents a group C?Y, wherein Y stands for

Abstract: The present invention belongs to the field of chemical pharmaceuticals, and specifically relates to compounds represented by formula I having a 9,9,10,10-tetrafluoro-9,10-dihydrophenanthrene structure and being able to inhibit hepatitis C virus activity, or a pharmaceutically acceptable salt, isomer, solvate, crystal or prodrug of said compounds, a pharmaceutical composition containing said compounds, and an application of said compounds or composition in the preparation of a drug. The compounds of the present invention have a good HCV inhibitory effect.

Abstract: An alternating-current full magnetic power machine includes a stator and a rotor. The stator includes a stator iron core and multiple coil windings that are built in a cable trough of the stator iron core in sequence, a pole of the stator iron core is provided with a groove, a stator the permanent magnet is disposed in the groove, a metal-plate of a fence-like mesh structure is fixed on a pole surface, and multiple stator composite magnetic heads made of the stator the permanent magnet and the metal-plate are disposed in the coil windings, the pole, and the groove. The rotor includes a rotor iron hoop made of a compound material, a non-magnetic material surface of the rotor iron hoop is provided with multiple rotor permanent magnets, and a metallic copper or an aluminous squirrel cage closed frame is disposed on a rotor permanent magnet surface.

Abstract: The present disclosure is applicable to the field of information technologies, and provides a route information displaying method and apparatus. The method includes: creating a three-dimensional coordinate system, and loading an electronic map in the XY plane of the three-dimensional coordinate system; acquiring, by using a satellite positioning system, a real-time location of a mobile terminal and a real-time speed, of the mobile terminal, corresponding to the real-time location; and drawing both a moving route and a speed curve of the mobile terminal in the three-dimensional coordinate system according to the acquired real-time location and real-time speed, where the real-time location of the mobile terminal is represented in the XY plane of the three-dimensional coordinate system, and the real-time speed of the mobile terminal is represented on the Z axis of the three-dimensional coordinate system.

Abstract: Disclosed is as a substituted thiazolamine derivative represented by Formula I or a pharmaceutically acceptable salt thereof or a hydrate thereof (the definitions of each group in the formula are as presented in the description), and the application thereof in the prevention and/or treatment of viral diseases induced by picornavirus. Also disclosed is a pharmaceutical composition containing the compound.

Abstract: Architecture that decomposes of one or more monolithic data concepts into atomic concepts and related atomic concept dependencies, and provides streaming data processing that processes individual or separate (atomic) data concepts and defined atomic dependencies. The architecture can comprise data-driven data processing that enables the plug-in of new data concepts with minimal effort. Efficient processing of the data concepts is enabled by streaming only required data concepts and corresponding dependencies and enablement of the seamless configuration of data processing between stream processing systems and batch processing systems as a result of data concept decomposition. Incremental and non-incremental metric processing enables realtime access and monitoring of operational parameters and queries.

Abstract: A vehicle system and method that can determine object sensor misalignment while a host vehicle is being driven, and can do so within a single sensor cycle through the use of stationary and moving target objects and does not require multiple sensors with overlapping fields of view. In an exemplary embodiment where the host vehicle is traveling in a generally straight line, one or more object misalignment angle(s) ?o between an object axis and a sensor axis are calculated and used to determine the actual sensor misalignment angle ?.

Abstract: Provided are a compound of formula I which can be used as a drug against small RNA virus infections, and optical isomers, pharmaceutically acceptable salts, solvates or hydrates thereof. Also provided are the preparation method of the compound, the method for using the compound for treating bacterial infections and the use of the compound in the preparation of a drug for preventing and/or treating viral diseases caused by small RNA viruses.

Abstract: The present invention provides a location information notification method, a user equipment, and an application service gateway. The method includes: acquiring, by a user equipment UE, current camping location information through an application programming interface API; performing, by the UE, matching between the current camping location information and a preset location information configuration table; and sending out, by the UE, corresponding prompt information according to a matching result. In addition, a user equipment and an application service gateway are provided.

Abstract: A novel nucleoside phosphoramidate compound, or a stereoisomer, salt, hydrate, solvate or crystal thereof for the treatment of Flaviviridae family viral infection, especially hepatitis C viral infection is provided. The pharmaceutical composition having the compound, or a stereoisomer, salt, hydrate, solvate or crystal thereof and a use of the compound or the composition in the treatment of Flaviviridae family viral infection, especially hepatitis C viral infection. The compound has a good anti-HCV effect.

Abstract: A heat exchange, which includes a casing having a cylinder; two connectors respectively attached to one end of the cylinder through the small opening; two convex heads respectively connected through the opening end to the large opening of a connector; a core disposed inside the casing; and two heat transfer medium passages. In this way, the space at the ends of the casing of the heat exchanger may be enlarged, thereby providing a space large enough to accommodate the construction personal and better working environment for two-side welding and future maintenance and wider selection range of material of the casing of the heat exchanger; a buffer area is provided for the flow of the heat transfer medium, and the auxiliary like baffles may be mounted inside the convex heads as required to further improve the heat exchange efficiency and reduce the cost.

Abstract: A method and device for panorama-based inter-viewpoint walkthrough and a machine readable medium are provided. The method includes: selecting a current viewpoint image from a panorama, and obtaining a three-dimensional model of the current viewpoint image; selecting a sub-image from the current viewpoint image to perform a feature detection, so as to obtain feature points of neighboring viewpoints; performing a matching calculation on the feature points of the neighboring viewpoints, and determining a distance between the neighboring viewpoints according to a result of the matching calculation; and performing three-dimensional walkthrough on the three-dimensional model of the current viewpoint image, where a walkthrough depth is the distance between the neighboring viewpoints.

Abstract: Disclosed are pyridazine derivatives represented by Formula I or pharmaceutically acceptable salts or hydrates thereof, pharmaceutical compositions comprising the compounds, methods of treating and/or preventing diseases or disorders associated with viral infections in patients using the compounds, and the use of the compounds in preparing the medicaments for treating and/or preventing diseases or disorders associated with viral infections. The compounds represented by Formula I have antiviral activity, especially anti-microRNA viral activity. Symbols in the compounds represented are described in the specification.

Abstract: Disclosed are pyridazine derivatives represented by Formula I or pharmaceutically acceptable salts or hydrates thereof, pharmaceutical compositions comprising the compounds, methods of treating and/or preventing diseases or disorders associated with viral infections in patients using the compounds, and the use of the compounds in preparing the medicaments for treating and/or preventing diseases or disorders associated with viral infections. The compounds represented by Formula I have antiviral activity, especially anti-microRNA viral activity. Symbols in the compounds represented are described in the specification.

Abstract: Disclosed is as a substituted thiazolamine derivative represented by Formula I or a pharmaceutically acceptable salt thereof or a hydrate thereof (the definitions of each group in the formula are as presented in the description), and the application thereof in the prevention and/or treatment of viral diseases induced by picornavirus. Also disclosed is a pharmaceutical composition containing the compound.

Abstract: The present invention provides a location information notification method, a user equipment, and an application service gateway. The method includes: acquiring, by a user equipment UE, current camping location information through an application programming interface API; performing, by the UE, matching between the current camping location information and a preset location information configuration table; and sending out, by the UE, corresponding prompt information according to a matching result. In addition, a user equipment and an application service gateway are provided.

Abstract: Use of BUBR1 as a biomarker for predicting the response to a compound, preferably resistance of a disease such as cancer in a subject, wherein the compound is a furazanobenzimidazole compound of general formula (I).

Abstract: The invention relates to a cooler for low-temperature methanol washing gas, which comprises a first heat exchanger and a second heat exchanger. The first heat exchanger includes a first housing, a first board, and a first heat exchange tube. The first housing is provided with a first feed gas inlet, a first feed gas outlet, a first heat transfer medium inlet, and a first heat transfer medium outlet. The second heat exchanger includes a second housing, a second board, and a second heat exchange tube. The second housing is provided with a second feed gas inlet, a second feed gas, a second heat transfer medium inlet, and a second heat transfer medium outlet. The second housing and the second board of the second heat exchanger may be made with a relatively thin plate, thereby enormously reducing the material and manufacturing cost for the invention with meeting the requirements of the production.

Abstract: Disclosed are pyridazine derivatives represented by Formula I or pharmaceutically acceptable salts or hydrates thereof, pharmaceutical compositions comprising the compounds, methods of treating and/or preventing diseases or disorders associated with viral infections in patients using the compounds, and the use of the compounds in preparing the medicaments for treating and/or preventing diseases or disorders associated with viral infections. The compounds represented by Formula I have antiviral activity, especially anti-microRNA viral activity. Symbols in the compounds represented are described in the specification.