Abstract: The present invention discloses an antibody specifically binding to a human endothelin receptor and uses thereof, where the antibody can inhibit the functions of the human endothelin receptor. The present invention includes the preparation, cloning, expression, and characterization of the antibody. The present invention can be used to effectively treat pulmonary arterial hypertension, a disease associated with pulmonary arterial hypertension, and a reproductive organ cancer in a human.

Abstract: A user identity verification method is disclosed. The method includes receiving an identity verification request sent by a user through a client terminal; determining a user communication number according to the identity verification request and generating a corresponding temporary communication number for the user communication number; recording the user communication number and the temporary communication number as first data; returning the temporary communication number to the client terminal; receiving a call request initiated by the user to the temporary communication number; determining a respective user communication number and a respective temporary communication number corresponding to the call request as second data; verifying whether the first data matches with the second data; and returning a verification result to the client terminal. The method can improve security and reliability of identity verification, reduce a user's waiting time, and enhance user experience.

Abstract: Aspects of the present disclosure provide techniques for design of synchronization signals for narrowband operation and other clean-slate, OFDM based systems such as enhanced component carrier (eCC) systems. An example method is provided for operations which may be performed by a BS to generate and transmit a dual-layer PSS, and correspondingly, techniques for a UE to detect the dual-layer PSS. The PSS may be generated utilizing a binary code cover and at least one sequence applied to a number of symbols within one or more subframes of a frame.

Abstract: Aspects of the present disclosure provide techniques for uplink (UL) data channel design. An example method is provided for operations which may be performed by a first apparatus. The example method generally comprises determining a number of pilot symbols to transmit for one or more slots of a first subframe based, at least in part, on a coverage enhancement (CE) level, and transmitting at least one uplink data channel having the determined number of pilot symbols in the one or more slots of the first subframe.

Abstract: An electronic device includes one or more unit pixels with a first node, a second node, and a third node. The device includes light-emitting-diode (LED) voltage (Vled) sensing circuitry, that senses Vled of the one or more unit pixels, by: sampling a charge of a capacitor of the one or more unit pixels, transitioning from the sampling, and reading out the Vled based upon a change in the charge of the capacitor, such that an operation of the unit pixel may be modified based upon the Vled.

Abstract: An electronic device includes one or more unit pixels and threshold voltage (Vth) sensing circuitry. The threshold voltage sensing circuitry senses Vth of the one or more unit pixels, by: sampling a charge of a capacitor of the one or more unit pixels, transitioning from the sampling, and reading out the threshold voltage based upon a change in the charge of the capacitor, such that an operation of the one or more unit pixels may be modified based upon the threshold voltage.

Abstract: A method of establishing an anti-attack public key cryptogram includes (1) two parties select a braid group Bn with n?7, and Bn=?1, ?2, . . . , ?n?1| ?i?j=?j?i, |i?j|?2, ?i?i+1?i=?i+1?i?i+1, 1?i?n?2, (2) the two parties select two subgroups A and B in Bn generated from a1, a2, . . . , ak and b1, b2, . . . , bm respectively, (3) the first party selects an element x=x (a1, a2, . . . , ak)?A as a first private key, and sends x?1b1x, x?1b2x, . . . , x?1bmx to the second party, (4) the second party selects an element y=y (b1, b2, . . . , bm)?B as a second private key, and sends y?1a1y, y?1a2y, . . . , y?1aky to the first party, (5) the first party obtains KA=x?1x(y?1a1y, y?1a2y, . . . , y?1aky)=x?1y?1xy, (6) the second party obtains y?1y(x?1b1x, x?1b2x, . . . , x?1bkx)=y?1x?1yx, and calculates to obtain KB=(y?1x?1yx)?1=x?1y?1xy, thereby reaching a shared secret key K=KA=KB.

Abstract: Systems and methods are provided for generating a nonlinear clock signal. Such a signal may be used to drive sub-pixels of an electronic display. The electronic display may include a microdriver that drives at least one sub-pixel based at least in part on an image data signal and an emission clock signal. The image data signal specifies a gray level for driving the sub-pixel and the emission clock signal includes a series of pulses of monotonically increasing pulse widths to enable the microdriver to drive the sub-pixel to emit light for a particular amount of time associated with the gray level. An emission timing controller may generate the emission clock signal.

Abstract: Methods and devices for encoding and decoding video using mode-dependent context determination in the case of level-run pair coding of transform coefficients are described. Intra-coding modes may be grouped into classes and each class may be associated with a partitioning of a coefficient group into regions. The region in which a coefficient falls determines, in part, the context selected for encoding bins associated with that coefficient, including a level, if the coefficient is non-zero, and a run if the coefficient correspond to the bin of a binarized run value.

Abstract: Provided herein are a stable solution formulation of an ETAR antibody, and use thereof in treating, preventing, or alleviating one or more symptoms of pulmonary arterial hypertension or one or more symptoms of cancer of a reproductive organ.

Abstract: Aspects of the present disclosure provide techniques for design of synchronization signals for narrowband operation and other clean-slate, OFDM based systems such as enhanced component carrier (eCC) systems. An example method is provided for operations which may be performed by a BS to generate and transmit a dual-layer PSS, and correspondingly, techniques for a UE to detect the dual-layer PSS. The PSS may be generated utilizing a binary code cover and at least one sequence applied to a number of symbols within one or more subframes of a frame.

Abstract: Aspects of the present disclosure provide techniques for uplink (UL) data channel design. An example method is provided for operations which may be performed by a first apparatus. The example method generally comprises determining a number of pilot symbols to transmit for one or more slots of a first subframe based, at least in part, on a coverage enhancement (CE) level, and transmitting at least one uplink data channel having the determined number of pilot symbols in the one or more slots of the first subframe.

Abstract: Aspects of the present disclosure provide techniques for design of channel raster for narrowband operation. One example method, performed by a base station, generally includes determining, based on one or more conditions, an exact frequency location of one channel of one or more channels to perform narrowband communications with a user equipment. The method also includes transmitting an indication of the one or more conditions to the user equipment. The method further includes communicating with the UE, based at least in part on the exact frequency location of the one channel.

Abstract: Novel oxalate oxidases are provided, which have suitable oxalate degrading activity near physiological pH (7.4). The properties of these OxOx make them potential drug candidates for use in reducing oxalate concentration in patients suffering from excess of oxalate. Especially due to the high activity at physiological pH, the OxOx's are suitable drug candidates for parenteral administration, i.e. to reduce the oxalate concentration in the plasma.

Abstract: The present invention relates to a method for preparing a sulfur-resistant catalyst for aromatics saturated hydrogenation, comprising the steps of: preparing noble metal impregnation solutions from a noble metal and deionized water or an acid solution; impregnating a carrier with the impregnation solutions sequentially from high to low concentrations by incipient impregnation; homogenizing, drying, and calcinating to obtain the sulfur-resistant catalyst for aromatics saturated hydrogenation. The catalyst for aromatics saturated hydrogenation prepared by the method according to the present invention is primarily used in processing low-sulfur and high-aromatics light distillate, middle distillate, atmospheric gas oil, and vacuum gas oil.

Abstract: Aspects of the present disclosure provide techniques for design of synchronization signals for narrowband operation, which can be used for stand-alone/in-band/guard-band deployment. An example method is provided for operations which may be performed by a base station (BS). The example method generally includes generating a primary synchronization signal (PSS) utilizing a first code sequence and a cover code applied to the first code sequence over a first number of symbols within one or more subframes, generating a secondary synchronization signal (SSS) based on a second code sequence over a second number of symbols within one or more subframes, and transmitting the PSS and the SSS in the first and second subframes to a first type of a user equipment (UE) that communicates on one or more narrowband regions of wider system bandwidth.

Abstract: Disclosed in the present invention is an antibody specifically binding to GLP-1R and a fusion protein thereof with GLP-1. The fusion proteins can effectively bind to a human GLP-1R receptor and activate a receptor signaling pathway, thus are useful for treating diabetes, excessive weight, obesity and related disorders thereof.

Abstract: Disclosed are a data transmission method, apparatus and system for realizing, when a UE is in a non-connected state, that shunting transmission of a local service can be completed, and that the use efficiency of a wireless resource can be improved. The data transmission method comprises: after a data packet sent by a local service server is received by an MEC server, when it is determined that a UE for receiving the data packet is in an RRC non-connected state, sending the data packet corresponding to the UE to a P-GW so as to trigger a paging process of the UE; and the MEC server querying, in a pre-set duration, downlink bearer information for transmitting the data packet to the UE, and when the downlink bearer information is found, sending the data packet according to the downlink bearer information.

Abstract: Embodiments relate to a voltage oscillator (VCO) that uses a replica bias circuit to generate a cascode bias voltage. The VCO generate an output periodic signal having a frequency and phase that is less or not susceptible to voltage swings by using a bias voltage generated in a replica bias circuit that replicates a voltage-to-current converter in the VOC. The bias voltage is generated and regulated according to a power supply voltage that supplies power to the VCO to account for voltage variations in the power supply voltage.

Abstract: In one embodiment, a method includes receiving first network usage data for user devices indicating activity by the user devices on webpages, determining first-level cluster centroids based on the first network usage data, and assigning each user device to at least one first-level cluster centroid. The method also includes determining second-level cluster centroids based on the first network usage data for user devices assigned to a particular first-level cluster centroid, and assigning each user device previously assigned to the particular first-level cluster centroid to at least one second-level cluster centroid. The method further includes determining clusters based on the first-level cluster centroids and the second-level cluster centroids, assigning each user device to at least one cluster, and sending one or more first notifications to user devices associated with a particular cluster.