Abstract: The present disclosure relates to use of a Clostridium ghonii spore combined with pembrolizumab in cancer treatment. It is found for the first time that the Clostridium ghonii spore combined with pembrolizumab can significantly improve a curative effect of colon cancer and reduce a dose of the pembrolizumab, and thus is efficient and low-toxic. Oncolysis by Clostridium ghonii can affect immunogenicity of a tumor microenvironment (TME) by various ways, converts an immunosuppressive state of the TME into an immune-activated state, adjusts the immunosuppressive TME, and breaks an immune tolerance. An optimal combination of the Clostridium ghonii spore and the pembrolizumab thoroughly removes about 20% of mouse tumor tissues. A benefit range of patients with tumors treated by a PD-1 antibody is expanded. The combination even has an obvious curative effect on patients failed the treatment by the PD-1 antibody.

Abstract: Disclosed is a method for reducing pressure and increasing injection by continuous operation system of biological acid acidification and nano coating, specifically including composition and preparation method of biological acidizing agent and nano coating agent. The method for reducing pressure and increasing injection by continuous operation system of biological acid acidification and nano coating of the present disclosure is able to effectively dredge the stratum water flow channel, reduce the water flow resistance, and achieve the effect of high-efficiency pressure reduction and injection increase of the water injection well.

Abstract: A soft boundary structure is implemented using a resonator structure capable of receiving sound or vibration, establishing resonance coupled with received sound or vibration, and creating a reflection with a pi phase factor. A soft boundary is located on or closely adjacent the resonator structure. The soft boundary cooperates with the resonator structure to attenuate the sound or vibration.

Abstract: The present disclosure provides an automatic minor repair operation system for an oil field, a pipe column conveying and discharging device for use in an automatic minor repair operation apparatus system, an anti-opening mechanism for an elevator and a turnover elevator, a manipulator and a workover operation device for a workover operation, an integrated automatic wellhead operation apparatus, and a power slip for an oil field workover operation. The automatic minor repair operation apparatus system includes: a workover machine, a pipe column conveying and discharging device, an elevator for a workover operation, a manipulator for a workover operation, an integrated automatic wellhead operation apparatus, and a power slip for an oil field workover operation.

Abstract: The present disclosure provides automated equipment for drilling and workover operations of oil field, and an oil field workover operation device, an integrated hydraulic clamp, a buckling apparatus and a string automated operating apparatus, and a derrick floor pipe handling manipulator for use in the automated equipment. The automated equipment comprises a workover rig, a derrick floor, an elevator, a monkey-board string automatic placement apparatus, a slip, an oil field workover operation device, a power clamp, and a derrick floor pipe handling manipulator, and the workover rig, the derrick floor, the elevator, the monkey-board string automatic placement apparatus, the slip, the oil field workover operation device, the power clamp, and the derrick floor pipe handling manipulator cooperate with each other to realize a lifting operation and a lowering operation of a string at a wellhead.

Abstract: Apparatus and methods are provided for UE to receive multicast services in RRC INACTIVE state. In one novel aspect, the UE joins a multicast session, receives an initial multicast configuration from a serving cell for the multicast, monitors a common multicast signaling for the multicast session in the RRC INACTIVE state and updates the multicast configuration based on the common multicast signaling upon detecting one or more predefined triggering conditions. In one embodiment, the UE updates the multicast configuration without notifying network. In another embodiment, the UE determines to perform a handover to a target cell upon detecting the source channel quality is below a predefined threshold. In one embodiment, the UE performs handover to the target cell after reconfiguring the multicast to the target cell. In one embodiment, the initial multicast configuration is received in an RRC Reconfiguration message or an RRC Release message.

Abstract: Apparatus and methods are provided for L1/L2-triggered mobility (LTM) cell switch. In one novel aspect, the UE performs an LTM handover by selecting and using the best beam taking advantage of the ping-pong effect of frequent cell switches for intra-CU with inter-DU and intra-DU cell switches. In one embodiment, the UE receives pre-configuration for the LTM, configures a second protocol stack based on the pre-configuration, configures a cell switch (CS) bearer upon receiving a cell switch command, wherein the CS bearer is associated to the source cell and the target cell. The UE performs the LTM handover based on the CS bearer. In one embodiment, the pre-configuration included multiple candidate cells and the UE configures the second protocol stack with multiple RLC entities. The MAC entity of the second protocol stack is a master cell group (MAC) MAC entity, which can be associated to multiple cells and multiple RLC entities.

Abstract: Apparatus and methods are provided for the UE to receive multicast transmission in RRC INACTIVE state. In one embodiment, the UE joins a multicast session, receives a MRB configuration for a multicast service, establishes an MRB for reception of the multicast service in the RRC INACTIVE state, and receives data transmission of the multicast service with the established MRB in the RRC INACTIVE state. In one embodiment, the UE stores the MRB configuration in the buffer when the multicast session has not started when the MRB configuration is received. In one embodiment, the UE receives a notification for the multicast session start in the RRC INACTIVE state and establishes the MRB based on the stored MRB configuration. In one embodiment, the UE, in the INACTIVE state, updates the multicast resource/MTCH information based on one or more predefined conditions.

Abstract: Apparatus and methods are provided for control plane inter-cell beam management with mobility. In one novel aspect, UE receives a pre-configuration message from the base station before a cell switch command; performs L1 measurements based on the pre-configuration; and receives the cell switch command via MAC CE. The UE, after receiving the pre-configuration message, performs DL sync procedure and UL time alignment procedure before or after the cell switch command. In another novel aspect, the base station sends an RRC pre-configuration to UE including configuration for one or more candidate cells before a cell switch command; receives L1 measurement report for the one or more candidate cells from the UE; and sends the cell switch command to the UE carried in a MAC CE. In one embodiment, the base station keeps UE context of the UE after the UE switched to the one or more candidate cell.

Abstract: Apparatus and methods are provided for inter-DU inter-cell cell switch with beam management. In one novel aspect, the UE receives a cell switch command, performs RLC reestablishment and MAC reset, sends a PDCP status report to indicate one or more PDCP protocol data units (PDUs) failed for a downlink (DL) or UL data transfer to the source cell for unacknowledged mode (UM) or acknowledge mode (AM) radio bearers, and performs a UE self-detected PDCP retransmission for UL data transfer when the UE detects one or more source-failed UL PDCP PDUs. The PDCP entity performs PDCP retransmission to the target cell. In one embodiment, the RLC entity identifies source-failed PDUs. In another embodiment, UE sends the pending RLC PDUs the PDCP entity and the PDCP entity identifies the source-failed PDUs. In one embodiment, UE triggers, compiles, and sends PDCP status report to the target cell.

Abstract: Apparatus and methods are provided for TA maintenance and acquisition for mobility with inter-cell beam management. In one novel aspect, the source TAG is maintained with the associated TAT running when cell switch is performed to switch from the source cell to a target cell and skips the RA procedure when a valid target TAG exists. In one embodiment, the target TAG is valid when there is the target TAG exists and a TAT of the target TAG is running. The UE performs a RA to the target when the UE determines that there is no TAG associated with the target or when a TAT of the target TAG expires. The source cell and the target cell belong to the same cell group or different cell group. In one embodiment, the UE performs a partial MAC reset and maintaining a TAT associated with the source cell.

Abstract: In one embodiment, a personal care appliance includes an electric motor having a drive shaft. In response to a voltage signal, the drive shaft is oscillated in an oscillatory motion having an oscillation amplitude. A control circuit includes, in operable cooperation, a user interface, a processor, a pulse width modulation signal generator, and a power source. The control circuit supplies the voltage signal to the electric motor, the voltage signal having a frequency and a duty cycle. The control circuit varies the frequency and the duty cycle of the voltage signal in response to an oscillation adjustment input received from the user interface so that the oscillation amplitude of the drive shaft is varied along a substantially linear rate of change profile relative to the frequency.

Abstract: A method for application-specific traffic handling is provided. A service data unit (SDU) can be received at a radio protocol layer in a radio access network (RAN) protocol stack. The SDU carries application data that is generated from an application layer and passes through multiple protocol layers existing between the application layer and the radio protocol layer. At the radio protocol layer, the SDU is inspected to obtain characteristic information from one or more protocol headers corresponding to one or more protocol layers among the multiple protocol layers. The characteristic information indicates characteristics of the application data. At the radio protocol layer, the SDU is classified into one of multiple classes based on the characteristic information obtained from the one or more protocol headers. At the radio protocol layer, the SDU is processed according to which one of the multiple classes the SDU is classified into.

Abstract: In one embodiment, a personal care appliance includes an electric motor having a drive shaft. In response to a voltage signal, the drive shaft is oscillated in an oscillatory motion having an oscillation amplitude. A control circuit includes, in operable cooperation, a user interface, a processor, a pulse width modulation signal generator, and a power source. The control circuit supplies the voltage signal to the electric motor, the voltage signal having a frequency and a duty cycle. The control circuit varies the frequency and the duty cycle of the voltage signal in response to an oscillation adjustment input received from the user interface so that the oscillation amplitude of the drive shaft is varied along a substantially linear rate of change profile relative to the frequency.

Abstract: Apparatus and methods are provided for setting initial PDCP state variables for multicast services. In one novel aspect, the UE sets initial PDCP state variables for the MBS session based on configuration values received from the network. In one embodiment, the UE receives dedicated RRC signaling from the network, which contains initial HFN value and the SN of the next PDCP PDU to be transmitted. In one embodiment, the one or more configuration values are provided in RRC Reconfiguration, RRCResume, or RRCSetup message, according to different RRC states of UE. In one embodiment, the UE initializes the RX_DELIV value based on the configuration value of HFN and SN received from the wireless network. When receiving the one or more configuration values of initial PDCP state variables, UE sets HFN to initial HFN value and sets RX_DELIV to the COUNT value of next PDCP PDU to be transmitted by network.

Abstract: A method and apparatus for training a compound property prediction model, a device, a storage medium and a program product. A implementation of the method comprises: acquiring an unannotated compound data set; pre-training a graph neural network using the unannotated compound data set to obtain a pre-trained graph neural network; acquiring a plurality of annotated compound data sets, each annotated compound data set being annotated with one kind of compound property; and performing multi-task training on the pre-trained graph neural network using the plurality of annotated compound data sets, to obtain a compound property prediction model, the compound property prediction model being used to predict a plurality kinds of properties of a compound.

Abstract: An electronic device is provided, including a device shell and a flight photographing device. The device shell is provided with an opening and an inner cavity. The opening communicates with the inner cavity. The flight photographing device is movably arranged on the device shell. The flight photographing device is capable of extending out of the device shell through the opening or retracting into the device shell. In a case that the flight photographing device is located outside the device shell, the flight photographing device is separable from the device shell.

Abstract: The present disclosure discloses an affinity prediction method and apparatus, a method and apparatus for training an affinity prediction model, a device and a medium, and relates to the field of artificial intelligence technologies, such as machine learning technologies, smart medical technologies, or the like. An implementation includes: collecting a plurality of training samples, each training sample including information of a training target, information of a training drug and a test data set corresponding to the training target; and training an affinity prediction model using the plurality of training samples. In addition, there is further disclosed the affinity prediction method. The technology in the present disclosure may effectively improve accuracy and a training effect of the trained affinity prediction model.

Abstract: In one embodiment, a personal care appliance includes an electric motor having a drive shaft. In response to a voltage signal, the drive shaft is oscillated in an oscillatory motion having an oscillation amplitude. A control circuit includes, in operable cooperation, a user interface, a processor, a pulse width modulation signal generator, and a power source. The control circuit supplies the voltage signal to the electric motor, the voltage signal having a frequency and a duty cycle. The control circuit varies the frequency and the duty cycle of the voltage signal in response to an oscillation adjustment input received from the user interface so that the oscillation amplitude of the drive shaft is varied along a substantially linear rate of change profile relative to the frequency.

Abstract: A soft boundary structure is implemented using a resonator structure capable of receiving sound or vibration, establishing resonance coupled with received sound or vibration, and creating a reflection with a pi phase factor. A soft boundary is located on or closely adjacent the resonator structure. The soft boundary cooperates with the resonator structure to attenuate the sound or vibration.