Abstract: A wide-field microscopy system and method for imaging a sample include directing infrared light onto the sample to selectively heat the sample. Probe light is also directed onto the sample. An objective collects the probe light after it interacts with the sample. The collected probe light is detected at a detector. A relative distance between the objective and sample is adjusted to introduce an optical defocus enhancement to enhance detection of a change in detected probe light that is indicative of infrared absorption by the sample.

Abstract: A wide-field bond-selective optical coherence tomography (OCT) system and method for imaging a sample includes generating infrared light and directing the infrared light onto the sample to selectively heat the sample. Probe light is also directed onto the sample. A first actuator provides sample depth scanning with respect to a first objective in a reference arm of the system, and a second actuator provides sample depth scanning with respect to a second objective in a sample arm of the system. A detection system receives scattered probe light reflected from the sample. A change in the received probe light from the sample that is indicative of absorption of infrared light.

Abstract: A display substrate and a display device. In the display substrate, at least one of the inter-opening region, the first opening peripheral region and the second opening peripheral region includes a first virtual sub-pixel; the first signal line extends along a first direction and includes a first portion passing through the first opening peripheral region, the inter-opening region and the second opening peripheral region; the first portion passes through the first virtual sub-pixel, and the first virtual sub-pixel includes a first compensation capacitor, a first plate of the first compensation capacitor is in a same layer as the first portion of the first signal line and electrically connected with the first portion of the first signal line, and in a same layer as the second plate of the storage capacitor; the second plate is in a different layer from, insulated from, and overlaps with the first plate.

Abstract: Disclosed is a scanning interference photolithography system, comprising a heterodyne optical path, a first interference optical path, a second interference optical path, a motion platform and a control subsystem, wherein a substrate is carried on the motion platform, a displacement measurement interferometer is used to measure the displacement of the motion platform, a first light beam and a second light beam are focused on the substrate for interference exposure; the control subsystem generates instructions according to various measurement information, adjusts angles of corresponding devices or the phase of a light beam, and locks the phase shift of interference exposure fringes of the first light beam and the second light beam. The system has a high precision of fringe pattern locking and a high laser utilization rate, and can be used for producing a large-area high-precision dense grating line gradient periodic grating.

Abstract: The present disclosure provides a display module and a medical spliced display system. The display module includes: a display panel; a back plate including a bottom wall and a side frame connected to each other to define an accommodating space; and a frame including a retaining wall and a supporting platform and an insert on the retaining wall; at least a portion of the retaining wall surrounds the side frame; the supporting platform extends toward the inside of the accommodating space for supporting the display panel; the insert is on a side of the side frame facing the accommodating space, to embed the side frame between the retaining wall and the insert.

Abstract: An example electronic device includes a network communication interface to connect to a conference server, a central control device communication interface to connect to a local central control device, a microphone and a processor. The processor is to receive audio at the microphone and send the audio to the local central control device and to the conference server. The processor is to send the audio to the local central control device such that it is received by a nearby electronic device before the audio is received from the conference server by the nearby electronic device.

Abstract: Disclosed are a vertical motion protection method and device based on a dual-stage motion system of a photolithography machine. The method comprises: according to a distance between measured points and reference points of the eddy current sensor and coordinates of the reference points of the eddy current sensor, calculating coordinates of the measured points on a lower surface of the micro-motion stage respectively; calculating a point normal form equation of the micro-motion stage at the current time using measured coordinates of the measured points on the micro-motion stage, then substituting X and Y coordinates of the measured points on the translated micro-motion stage to determine a maximum height of the micro-motion stage at the current time; and comparing the maximum height with a height threshold, if the maximum height exceeds the height threshold, shutting down for protection, or else continuing to operate the system.

Abstract: The disclosure provides for compounds and methods for modulating or inhibiting glutaminyl-peptide cyclotransferase-like protein (QPCTL). In one aspect, described herein are compounds of Formulas (I), (Ia), (Ib), (Iaa), (Iab), (Iba), (Ibb), (II), (IIa), (IIb), (IIaa) (IIab), (IIba), and (IIbb), stereoisomer thereof, or salts or solvates thereof. Further provided herein are methods of treating a disease or a condition comprising administering a compound of Formula (I), (Ia), (Ib), (Iaa), (Iab), (Iba), (Ibb), (II), (IIa), (IIb), (IIaa) (IIab), (IIba), or (IIbb), a stereoisomer thereof, or a salt or solvate thereof.

Abstract: A developing cartridge includes: a cartridge body for accommodating developers; a driving part at a first end in a first direction; a developing roller rotatable about a rotation axis extending along the first direction and positioned at a third end in a second direction; a storage medium for storing information; an electrical contact surface electrically connected to the storage medium and fixed relative to the cartridge body, and a lifting element configured to lift up the cartridge body in the third direction. The electrical contact surface is positioned at the first end in the first direction and is farther away from the developing roller relative to the driving part. The lifting element is farther away from the developing roller in the second direction away from the driving part.

Abstract: A propulsion module, a propulsion system, a watercraft, an assembly method for a propulsion module, an assembly method for a propulsion system and an assembly method for a watercraft are provided. The propulsion module includes a waterjet. The propulsion module also includes an electric motor configured to channel seawater through the waterjet, wherein in use, the electric motor is configured to be externally passively cooled by surrounding seawater. Further, the propulsion module includes an electronic speed controller (ESC) connected to the electric motor and configured to control the electric motor, wherein in use, the ESC is configured to be externally passively cooled by the surrounding seawater.

Abstract: Microscopic analysis of a sample includes a fluorescent dye disposed within the sample. A mid-IR optical source generates a mid-infrared beam, which is directed onto the sample to induce a temperature change by absorption of the mid-infrared beam. An optical source generates a probe beam directed to impinge on the sample. A detector detects fluorescent emissions from the sample when the probe beam impinges on the sample. A data acquisition and processing system acquires and processes the detected fluorescent emissions from the sample to: (i) generate a signal indicative of infrared absorption by the sample, (ii) generate a signal indicative of temperature in the sample based on the signal indicative of infrared absorption by the sample, (iii) generate an image of the sample using the signal indicative of temperature in the sample.

Abstract: Provided herein are acyclic oxazepinyl compounds useful in the treatment on cancers.

Abstract: Novel small molecule proteolysis-targeting chimeras (PROTACs) are provided, along with methods for their use as Bruton's tyrosine kinase (BTK) degraders. The small molecule PROTACs described herein are useful in treating and/or preventing BTK-related diseases, such as cancer, neurodegenerative disorders, inflammatory diseases, and metabolic disorders. Also provided are methods for inducing BTK degradation in a cell using the compounds and compositions described herein.

Abstract: Microscopic analysis of a sample includes a system using dark-field illumination. A mid-IR optical source generates a mid-infrared beam, which is directed onto the sample to induce a temperature change by absorption of the mid-infrared beam. A visible light source generates a light illuminating the sample on a substrate and creating a scattered field and a reflected field along a collection path of the system. A pupil mask is positioned along the collection path to block the reflected field while allowing the scattered field to pass therethrough. A camera is positioned at an end of the collection path to collect the scattered field and generate a dark-field image of the sample.

Abstract: Disclosed herein is an amplifier, comprising: an op-amp configured to receive at an input thereof a first electric current; a first MOS capacitor connected to the input and an output of the op-amp.

Abstract: With rapidly evolving technologies and emerging tools, sports-related videos generated online are rapidly increasing. To automate the sports video editing/highlight generation process, a key task is to precisely recognize and locate events-of-interest in videos. Embodiments herein comprise a two-stage paradigm to detect categories of events and when these events happen in videos. In one or more embodiments, multiple action recognition models extract high-level semantic features, and a transformer-based temporal detection module locates target events. These novel approaches achieved state-of-the-art performance in both action spotting and replay grounding. While presented in the context of sports, it shall be noted that the systems and methods herein may be used for videos comprising other content and events.

Abstract: The present application provides a model gradient update method and device, for use in improving the accuracy of model training. A central server repeatedly executes a gradient update process until a stop condition is satisfied. One gradient update process comprises: receiving first gradients respectively sent by multiple nodes, the first gradients being obtained by each node using sample data to train a model to be trained of the node one or more times; obtaining a second gradient one the basis of the multiple first gradients and the probability of each node in the present gradient update process, the probability of each node in the present gradient update process being determined by an Actor-Critic network one the basis of the probability of each node in the last gradient update process; and sending the second gradient to the multiple nodes, respectively.

Abstract: A floor-type air-conditioning indoor unit and an air conditioner are provided. The indoor unit has a housing, a top air outlet frame and a fan assembly. The housing has an installation port where the top air outlet frame is installed. The top air outlet frame is movable in an up-down direction and has a lower port and a front port. The fan assembly blows airflow from the air inlet to the lower port and out from the front port of the top air outlet frame. One of the top air outlet frame and the housing is provided with a sliding plate extending in the up-down direction, and the other is provided with a sliding groove engaging the sliding plate. A length of the sliding plate is longer than or equal to a maximum trip of the top air outlet frame in the up-down direction.

Abstract: A diagnostic method and system for measuring potential and electric field of plasma are provided. According to operation parameters of a magnetic confinement fusion device and relevant parameter data of a plurality of candidate particle elements, signal-noise ratios are calculated. to select a neutral beam particle element. Beam trajectories varying in incident velocity, incident angle and sampling area are obtained by iterative calculation, and a preset parameter which enables the beam trajectories to pass through an entrance slit of an analyzer is obtained. A neutral beam that meets the preset parameter is injected into the plasma. An energy of the primary beam generated by collision ionization in a sampling area is measured, and potential of the sampling area is obtained according to law of conservation of energy. Sampling areas are detected to obtain potential spatial distribution of the plasma and a radial electric field, and the diagnostic is finished.