Abstract: A tapered fiber optoacoustic emitter includes a nanosecond laser configured to emit laser pulses and an optic fiber. The optic fiber includes a tip configured to guide the laser pulses. The tip has a coating including a diffusion layer and a thermal expansion layer, wherein the diffusion layer includes epoxy and zinc oxide nanoparticles configured to diffuse the light while restricting localized heating. The thermal expansion layer includes carbon nanotubes (CNTs) and Polydimethylsiloxane (PDMS) configured to convert the laser pulses to generate ultrasound. The frequency of the ultrasound is tuned with a thickness of the diffusion layer and a CNT concentration of the expansion layer.

Abstract: A signal sending method includes generating M signals. The signal sending method also includes sending the M signals on M time-frequency resource elements. The M signals are in a one-to-one correspondence with the M time-frequency resource elements. At least two of the M time-frequency resource elements overlap in a frequency domain. Any two of the M time-frequency resource elements are free from overlapping in a time domain. M is an integer greater than 1.

Abstract: A device and a method for regulating and controlling an incident angle of a light beam in a laser interference lithography process are disclosed. The device comprises: a beam splitter prism between a first lens and a second lens, a first position detector, a first decoupling lens between the first position detector and the beam splitter prism, a feedback control system connected to the first position detector and a first universal reflecting mirror. The beam splitter prism reflects first incident light passing through the first universal reflecting mirror, the first decoupling lens enables a first reflected light enter into the first position detector, the first position detector measures the light beam position, the feedback control system outputs a control command according to the measurement result to regulate a mirror base of the first universal reflecting mirror, thereby regulating and controlling an incident angle of an exposure light beam.

Abstract: An integrated platform system that employ a series of machine learning techniques and prediction and detection units that can process input data and extract and generate meaningful insights and predictions therefrom. The system integrates together multiple different data storage types and applications that generates data of different types, and an associated processing system for processing the different data types, store the data in a common data model to normalize the data, determine the data lineage of the data, and then process the data using different types of techniques. The data can also be processed by a prediction unit for generating meaningful insights and predictions or by an anomaly detection unit for detecting one or more anomalies in the data.

Abstract: Methods of the present invention comprise photoinactivation of catalase in combination with low-concentration peroxide solutions and/or ROS generating agents to provide antibacterial effects.

Abstract: Systems and methods are provided for performing photothermal dynamic imaging. An exemplary method includes: scanning a sample to produce a plurality of raw photothermal dynamic signals; receiving the raw photothermal dynamic signals of the sample; generating a plurality of second signals by matched filtering the raw photothermal dynamic signals to reject non-modulated noise; and performing an inverse operation on the second signals to retrieve at least one thermodynamic signal in a temporal domain.

Abstract: An example photoacoustic system for neurostimulation includes a light producing device for producing light of a specific wavelength. At least one nanotransducer is binded on a surface of a neuron. The nanotransducer converts the light with the specific wavelength into at least one acoustic wave at or near the neuron.

Abstract: A method includes: obtaining a push content request from an object; determining a push content set according to the push content request; detecting historical behavior feature data of the object for a push content in response to a behavior feature of the object for the push content satisfying a preset negative behavior condition; performing content-based matching for the push content set based on the historical behavior feature data to obtain a target push content set of the object; performing content sorting of the push content set and performing content-based matching of the push content of the object to obtain a target push content set of the object; and determining a target push content of the object from the target push content set, and transmitting the target push content to the object.

Abstract: An apparatus for preparing polyalpha-olefins includes a mixing unit, a microchannel reaction unit, a high-pressure separation unit, a low-pressure separation unit, a gas circulation unit, a post-treatment unit and a pressure control unit, the mixing unit, the microchannel reaction unit, the high-pressure separation unit, the low-pressure separation unit that are successively connected. The gas circulation unit, the microchannel reaction unit is provided with the BF3 gas inlet, the mixing unit is provided with the auxiliary feed inlet, and the olefin raw material inlet, the gas circulation unit is connected with the BF3 gas inlet, the low-pressure separation unit is further connected with the post-treatment unit, and the high-pressure separation unit, the pressure control unit, and the gas circulation unit are further successively connected.

Abstract: A tapered fiber optoacoustic emitter includes a nanosecond laser configured to emit laser pulses and an optic fiber. The optic fiber includes a tip configured to guide the laser pulses. The tip has a coating including a diffusion layer and a thermal expansion layer, wherein the diffusion layer includes epoxy and zinc oxide nanoparticles configured to diffuse the light while restricting localized heating. The thermal expansion layer includes carbon nanotubes (CNTs) and Polydimethylsiloxane (PDMS) configured to convert the laser pulses to generate ultrasound. The frequency of the ultrasound is tuned with a thickness of the diffusion layer and a CNT concentration of the expansion layer.

Abstract: In some examples, a system receives measurement data obtained based on a non-destructive imaging of an identifiable structure within a three-dimensional (3D) object formed using an additive manufacturing machine, the identifiable structure formed based on control of a characteristic of a build material of a first internal object portion relative to a characteristic of the build material in a second internal object portion, the first and second internal object portions being within the 3D object. The system determines, based on the measurement data, a deviation of a physical property of the identifiable structure from a target physical property, and outputs information indicating the deviation.

Abstract: The disclosure provides for compounds and methods for modulating or inhibiting glutaminyl-peptide cyclotransferase-like protein (QPCTL). In one aspect, described herein are compounds of Formulas (I), (Ia), (Ib), (Iaa), (Iab), (Iba), (Ibb), (II), (IIa), (IIb), (IIaa) (IIab), (IIba), and (IIbb), stereoisomer thereof, or salts or solvates thereof. Further provided herein are methods of treating a disease or a condition comprising administering a compound of Formula (I), (Ia), (Ib), (Iaa), (Iab), (Iba), (Ibb), (II), (IIa), (IIb), (IIaa) (IIab), (IIba), or (IIbb), a stereoisomer thereof, or a salt or solvate thereof.

Abstract: Systems and methods for sensing vibrational absorption induced photothermal effect via a visible light source. A Mid-infrared photothermal probe (MI-PTP, or MIP) approach achieves 10 mM detection sensitivity and sub-micron lateral spatial resolution. Such performance exceeds the diffraction limit of infrared microscopy and allows label-free three-dimensional chemical imaging of live cells and organisms. Distributions of endogenous lipid and exogenous drug inside single cells can be visualized. MIP imaging technology may enable applications from monitoring metabolic activities to high-resolution mapping of drug molecules in living systems, which are beyond the reach of current infrared microscopy.

Abstract: A method for the determination of antibiotic susceptibility through stimulated Raman scattering microscopy is disclosed. The method utilizes a imaging apparatus adapted to collect a laser signal through a sample having a bacteria for imaging the metabolism of the sample. The sample can be manipulated with an antibiotic for imaging to determine the susceptibility of a bacteria to the provided antibiotic.

Abstract: Systems and methods for sensing vibrational absorption induced photothermal effect via a visible light source. A Mid-infrared photothermal probe (MI-PTP, or MIP) approach achieves 10 mM detection sensitivity and sub-micron lateral spatial resolution. Such performance exceeds the diffraction limit of infrared microscopy and allows label-free three-dimensional chemical imaging of live cells and organisms. Distributions of endogenous lipid and exogenous drug inside single cells can be visualized. MIP imaging technology may enable applications from monitoring metabolic activities to high-resolution mapping of drug molecules in living systems, which are beyond the reach of current infrared microscopy.

Abstract: Microscopic analysis of a sample includes a fluorescent dye disposed within the sample. A mid-IR optical source generates a mid-infrared beam, which is directed onto the sample to induce a temperature change by absorption of the mid-infrared beam. An optical source generates a probe beam directed to impinge on the sample. A detector detects fluorescent emissions from the sample when the probe beam impinges on the sample. A data acquisition and processing system acquires and processes the detected fluorescent emissions from the sample to: (i) generate a signal indicative of infrared absorption by the sample, (ii) generate a signal indicative of temperature in the sample based on the signal indicative of infrared absorption by the sample, (iii) generate an image of the sample using the signal indicative of temperature in the sample.

Abstract: The utility model relates to a noise reduction device for an outlet side of a fan, and a heat exchange system including the noise reduction device. The noise reduction device includes: a connecting portion configured to be connected with at least a part of the air duct cover, and form an accommodation space communicating with an airflow on the outlet side via at least one of the through holes; and at least one first chamber and/or at least one second chamber, the first chamber being located in the accommodation space and filled with a sound-absorbing material, and the second chamber being located in the accommodation space and configured as a resonant noise-reduction cavity. The utility model is easy to manufacture, install and maintain, the noise reduction effect is obvious, and therefore the utility model has significant practicability.

Abstract: A lesion detection system for use with a patient, comprising an optoacoustic guide wire assembly configured to be insertable into a patient's tissue. The optical acoustic guide wire assembly can be comprised of an optical waveguide have a first end and a second end, a light source coupled to the second end of the optical waveguide, wherein said light source configured to emit energy to the patient's tissue, at least one transducer configured to detect an ultrasound signal emitted from the patient's tissue in response to energy emitted from the light source, and a computer system.

Abstract: An apparatus for preparing polyalpha-olefins has an input unit (1), a microchannel reactor (2), and a post-treatment unit (3) that are successively connected. The input unit has a mixer and/or pipeline(s) for delivering an olefin raw material, an auxiliary feed and a BF3 catalyst to the microchannel reactor (2). The apparatus and process that utilizes the apparatus allow flexible and rapid mixing of the catalyst, the auxiliary feed and the olefin raw material, and have the advantages of high polymerization reaction speed, good mass and heat transfer effects, high reaction conversion, good product selectivity and excellent performance, thereby being suitable for large-scale industrial production.

Abstract: A semiconductor device including a plurality of nanosheet transistor channels adjacent to a source/drain. An inner spacer located between each of the plurality of nanosheet transistor channels and the inner spacer wraps around the end of each of the plurality of nanosheet transistors. The source/drain is in contact with the inner spacer and each of the plurality of nanosheet transistor channels. A gate surrounding each of the plurality of nanosheet transistor channels and an electrical contact connected to the source/drain. An ultra low-k spacer located between the gate and the source/drain. The ultra low-k spacer reduces the parasitic capacitance of the nanosheet transistor.