Abstract: A new set of bench-stable fluoroalkylphosphines that directly convert C—H bonds in pyridine building blocks, drug-like fragments, and pharmaceuticals, into fluoroalkyl derivatives. No pre-installed functional groups or directing motifs are required. The reaction tolerates a variety of sterically and electronically distinct pyridines and is exclusively selective for the 4-position in most cases. The reaction proceeds via initial phosphonium salt formation followed by sp2-sp3 phosphorus ligand-coupling, an underdeveloped manifold for C—C bond formation.

Abstract: A power supply system and a control method and control device thereof are provided. The power supply system includes a first power supply device, a heat-dissipation unit, a second power supply device, and a control device. The control device is configured to confirm whether each battery pack in the first power supply device experiences thermal runaway, and control the first power supply device to supply power to the heat-dissipation unit when no battery pack in the first power supply device experiences thermal runaway, so that the heat-dissipation unit dissipates heat from the first power supply device; and control a battery pack not experiencing thermal runaway in the first power supply device and/or the second power supply device to supply power to the heat-dissipation unit when a battery pack in the first power supply device experiences thermal runaway, so that the heat-dissipation unit dissipates heat from the first power supply device.

Abstract: An external wideband antenna and a wireless communication device are provided in the disclosure. The external wideband antenna includes a radio frequency (RF) coaxial cable, and a first antenna body and a second antenna body which are electrically connected with the RF coaxial cable respectively, where an outer contour of the first antenna body and an outer contour of the second antenna body cooperate to define a tapered slot. In the external wideband antenna provided the disclosure, the outer contour of the first antenna body and the outer contour of the second antenna body cooperate to define the tapered slot, which facilitates generation of a strong coupling current, and in turn a broadening of antenna bandwidth.

Abstract: A battery pack includes a battery column and a liquid cooling tube. The battery column includes at least two batteries, and the batteries are arranged in a first direction. The liquid cooling tube is disposed on a surface of the battery column and is configured to dissipate heat for the batteries. The liquid cooling tube includes cooling portions, and the cooling portions are portions having orthographic projections on the battery column. The orthographic projections of the cooling portions on the battery column are cooling regions. The cooling portions extend in a second direction, and the second direction is not parallel to the first direction.

Abstract: The disclosure relates a battery technology field, and in particular, relates to a battery pack. The battery pack includes a battery array and a liquid cooling tube. The battery array includes at least two batteries, and the batteries are arranged in a first direction. The liquid cooling tube is disposed on a surface of the battery array and is configured to dissipate heat for the batteries. The liquid cooling tube includes cooling portions, and the cooling portions are portions of an orthographic projection of the liquid cooling tube on the battery array. Orthographic projections of the cooling portions on the battery array are cooling regions. In the battery array, at least one of the batteries is located outside a range of the cooling portions.

Abstract: The invention discloses a method for analyzing the expansive stress and expansive strain of tunnel surrounding rock, including: (1) determining the surrounding rock state of the tunnel surrounding rock before expansion and the surrounding rock state after expansion; (2) according to the determined state of the surrounding rock, determining the expansive stress and expansive strain of the tunnel surrounding rock before expansion, and determining the expansive stress and expansive strain of the tunnel surrounding rock after expansion; (3) according to the surrounding rock state of the tunnel surrounding rock after expansion, the expansive deformation radius of the tunnel surrounding rock is determined, so as to determine the expansive deformation displacement of the tunnel surrounding rock.

Abstract: The invention discloses a method for analyzing the constitutive relationship of confined rock expansion, including: (1) determining parameters that affect rock expansive properties, wherein the parameters comprise category, density, and water content; (2) establishing an expression of the relationship between the parameters and rock expansive capacity; (3) establishing an expression of the relationship among the rock expansive capacity, rock expansive stress and rock expansive strain; and (4) determining an expression of the relationship among the parameters, the rock expansive stress and the rock expansive strain according to the rock expansive capacity. The present invention introduces parameters comprising category, density, and water content that affect the rock expansive properties into the analysis of rock expansive stress and rock expansive strain, which can truly reflect the variation of rock expansive stress and rock expansive strain, and can achieve quantized calculation of the rock expansive state.

Abstract: A device of correcting duty cycle includes: a duty cycle correcting circuit, a controller of the duty cycle correcting circuit and a duty cycle detecting circuit. The duty cycle correcting circuit generates a pair of phase-shifting clocks in accordance with a pair of complementary clocks and regenerates a regenerated clock in accordance with the pair of phase-shifting clocks. The controller of the duty cycle correcting circuit couples to the duty cycle correcting circuit. The duty cycle detecting circuit couples to the duty cycle correcting circuit and the controller of the duty cycle correcting circuit, and generates a detecting output to the controller of the duty cycle correcting circuit in accordance with a current duty cycle of the regenerated clock. The controller of the duty cycle correcting circuit controls the duty cycle correcting circuit in accordance with the detecting output to adjust the pair of phase-shifting clocks.

Abstract: A device (e.g., an application-specific integrated circuit chip) includes a memory module processing unit and an interface. The memory module processing unit is configured to receive an instruction to obtain values stored in one or more memory components and process the obtained values to return a processed result. The memory module processing unit is also configured to store the obtained values in a cache based on one or more criteria. The memory module processing unit is configured to be included on a computer memory module configured to be installed in a computer system. The interface is configured to communicate with the one or more memory components included on the computer memory module.

Abstract: The present invention relates generally to methods and kits for detecting one or more biomarkers, such as an Epidermal Growth Factor Receptor (EGFR) mutation, e.g., T790M mutation, L858R mutation, one or more exon19 insertions and/or one or more exon19 deletions in the EGFR gene, in a biological sample to aid in diagnosis, prognosis, monitoring, or therapy selection for a disease such as, for example, cancer. The methods and kits are useful in aiding in diagnosis, prognosis, monitoring, or therapy selection for lung cancer, e.g., non-small cell lung cancer (NSCLC).

Abstract: The present invention relates to a liquid crystal display device. The liquid crystal display device of the present invention comprises a first substrate, a second substrate, and a liquid crystal composition disposed between said first substrate and said second substrate, wherein said first substrate and said second substrate are disposed in parallel and opposite to each other; alignment layers are disposed on the sides of said first and second substrates that are close to said liquid crystal composition; and said alignment layers are provided with vertical alignment films that allow liquid crystal molecules in said liquid crystal composition to be arranged roughly perpendicular to said first and second substrates, with said liquid crystal molecules having a pretilt angle of 88.5° to 89.5°.

Abstract: The present disclosure is directed synthetic methods for the preparation of 4-valyloxybutyric acid. The synthetic methods described herein employ a diverse array of protecting group strategies and reaction conditions. Additionally, the present disclosure is directed to compounds useful as synthetic intermediates in the preparation of 4-valyloxybutyric acid.

Abstract: A roof laminate (10) includes a roof membrane (12, 100, 200, 300) and a protective sheet (14, 114, 214, 314) removably affixed thereto. The surface (20) of the roof membrane (12, 100, 200, 300) can be protected from dirt, scratches and scrapes by a protective sheet (14, 114, 214, 314) which also provides other beneficial attributes that aid an installer. The membrane (12, 100, 200) and the sheet (14, 114, 214) are heat laminated together in the absence of adhesive and tackifiers. Alternatively, the membrane (12, 300) and the sheet (14, 314) are surface treated and then brought into contact with one another in the absence of adhesive and tackifiers. The sheet (14, 114, 214, 314)) may be single layer or include at least a first layer (30) directly secured to a second layer (32). The first layer (30) provides at least one of UV protection, anti-slip, and anti-glare to the roof laminate (10) and so aids the installer in at least one of those respects.

Abstract: The invention is directed towards compounds (e.g., Formula (I)), their mechanism of action, and methods of modulating proliferation activity, and methods of treating diseases and disorders using the compounds described herein (e.g., Formula (I)).

Abstract: Provided are an organic electroluminescent material and a device thereof. The organic electroluminescent material is a metal complex containing a ligand La having a structure of Formula 1A and a ligand Lb, having a structure of Formula 1B. Such metal complexes are applicable to electroluminescent devices and can obtain a higher sublimation yield during sublimation and have a lower evaporation temperature and can provide better device performance such as an increased device lifetime and a narrower full width at half maximum. Further provided are an electroluminescent device containing the metal complex and a compound composition containing the metal complex.

Abstract: The present disclosure provides compositions and methods for selectively killing senescent cells, wherein the composition comprises a compound of Formula (I) or a compound of Formula (II). The selective killing of senescent cells may delay aging and/or treat age-related disorders.

Abstract: A roof assembly, having: a roof deck; an insulation board assembly mounted onto the roof deck; and a roofing membrane adhered onto the insulation board assembly, wherein the insulation board assembly comprises: a foam insulation board, a woven top facer on a top side of the foam insulation board, and a woven bottom facer on a bottom side of the foam insulation board.

Abstract: Compositions that include cationic surfactants and methods of synthesizing compositions that include cationic surfactants. The surfactants include a quaternary amine and a saturated or unsaturated alkyl chain with 4 to 28 carbons. The surfactants can be generated by reacting a fatty acid modified with an amino alkyl group and an epihalohydrin in the presence of a base. The cationic surfactants can be generated by reacting a fatty acid modified with an amino alkyl group, an epihalohydrin, and a carboxylic acid. The cationic surfactants can be generated by reacting a carboxylic acid, an epihalohydrin, and a catalyst to afford a halo-substituted alkyl ester, followed by reacting the halo-substituted alky ester with a fatty acid modified with an amino alkyl group.

Abstract: Compositions that include cationic surfactants and methods of synthesizing compositions that include cationic surfactants. The surfactants include a quaternary amine and a saturated or unsaturated alkyl chain with 4 to 28 carbons. The surfactants can be generated by reacting a fatty acid modified with an amino alkyl group and an epihalohydrin in the presence of a base. The cationic surfactants can be generated by reacting a fatty acid modified with an amino alkyl group, an epihalohydrin, and a carboxylic acid. The cationic surfactants can be generated by reacting a carboxylic acid, an epihalohydrin, and a catalyst to afford a halo-substituted alkyl ester, followed by reacting the halo-substituted alky ester with a fatty acid modified with an amino alkyl group.

Abstract: Compositions that include cationic surfactants and methods of synthesizing compositions that include cationic surfactants. The surfactants include a quaternary amine and a saturated or unsaturated alkyl chain with 4 to 28 carbons. The surfactants can be generated by reacting a fatty acid modified with an amino alkyl group and an epihalohydrin in the presence of a base. The cationic surfactants can be generated by reacting a fatty acid modified with an amino alkyl group, an epihalohydrin, and a carboxylic acid. The cationic surfactants can be generated by reacting a carboxylic acid, an epihalohydrin, and a catalyst to afford a halo-substituted alkyl ester, followed by reacting the halo-substituted alky ester with a fatty acid modified with an amino alkyl group.