Abstract: In one aspect, the disclosure relates to benzoylhydrazide-derived PROTACs that are highly effective at degrading HDAC3 and that are also capable of targeting, to a lesser extent, other HDAC isoforms, methods of making same, pharmaceutical compositions comprising same, and methods of treating cancers including hematologic cancers, breast cancer, other malignancies, and other serious diseases involving aberrant HDAC activity using the same. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

Abstract: Some embodiments provide a novel method for distributing control-channel communication load between multiple controllers in a network control system. In some embodiments, the controllers manage physical forwarding elements that forward data between several computing devices (also called hosts or host computers), some or all of which execute one or more virtual machines (VMs). The method of some embodiments distributes a controller assignment list to the host computers. The host computers use this list to identify the controllers with which they need to interact to perform some of the forwarding operations of their associated logical forwarding elements. In some embodiments, agents executing on the host computers (1) review the controller assignment list to identify the appropriate controllers, and (2) establish control channel communications with these controllers to obtain the needed data for effectuating the forwarding operations of their associated physical forwarding elements.

Abstract: This application discloses a radio frequency resource allocation method and apparatus, and an electronic device, and pertains to the field of communication technologies. The method includes: monitoring, in a case that a first data card triggers a first preset service, whether a first radio frequency resource requested by the first data card overlaps a second radio frequency resource occupied by a second data card; and allocating a third radio frequency resource to the second data card in a case that the second radio frequency resource overlaps the first radio frequency resource.

Abstract: An integrated circuit is disclosed. The integrated circuit includes a first resonator, a second resonator, and a coupling element. The first resonator has a first terminal and a second terminal, where the first resonator comprises a gain resistor, a gain capacitor, and a gain inductor in parallel and electrically coupling the first terminal with the second terminal. The second resonator has a third terminal and a fourth terminal, where the second resonator includes a loss resistor, a loss capacitor, and a loss inductor in parallel and electrically coupling the third terminal with the fourth terminal. The coupling element selectively couples the first terminal of the first resonator with the third terminal of the second resonator.

Abstract: A surfactant composition is provided. The composition includes chemical structure represented by Formula (1): where R1 represents a hydrocarbon group, a substituted hydrocarbon group, an alkyl ester group, or an alkyl amine having from 4 to 28 carbon atoms, and R2 and R3 represent hydrocarbon groups having from 1 to 5 carbon atoms. Also provided is a composition including a brine comprising a total salinity of at least 20,000 mg/L and the chemical structure shown in Formula (1). Methods of making a composition including the chemical structure represented by Formula (1) are also provided.

Abstract: The mask includes an evaporation surface and a glass surface facing away from the evaporation surface. The mask is provided with a plurality of evaporation holes distributed in an array. The evaporation hole penetrates the evaporation surface and the glass surface, and the evaporation hole includes a first opening on the evaporation surface and a second opening on the glass surface. An orthographic projection of the first opening on the glass surface is a first projection opening, and the first projection opening covers the second opening. An interval between the first projection opening and the second opening in a first direction of tensioning the mask is a first interval. An interval between the first projection opening and the second opening in a second direction perpendicular to the first direction is a second interval. The second interval is less than the first interval.

Abstract: Compositions that include cationic surfactants and methods of synthesizing compositions that include cationic surfactants. The surfactants include a quaternary amine and a saturated or unsaturated alkyl chain with 4 to 28 carbons. The surfactants can be generated by reacting a fatty acid modified with an amino alkyl group and an epihalohydrin in the presence of a base. The cationic surfactants can be generated by reacting a fatty acid modified with an amino alkyl group, an epihalohydrin, and a carboxylic acid. The cationic surfactants can be generated by reacting a carboxylic acid, an epihalohydrin, and a catalyst to afford a halo-substituted alkyl ester, followed by reacting the halo-substituted alky ester with a fatty acid modified with an amino alkyl group.

Abstract: Compositions that include cationic surfactants and methods of synthesizing compositions that include cationic surfactants. The surfactants include a quaternary amine and a saturated or unsaturated alkyl chain with 4 to 28 carbons. The surfactants can be generated by reacting a fatty acid modified with an amino alkyl group and an epihalohydrin in the presence of a base. The cationic surfactants can be generated by reacting a fatty acid modified with an amino alkyl group, an epihalohydrin, and a carboxylic acid. The cationic surfactants can be generated by reacting a carboxylic acid, an epihalohydrin, and a catalyst to afford a halo-substituted alkyl ester, followed by reacting the halo-substituted alky ester with a fatty acid modified with an amino alkyl group.

Abstract: Some embodiments provide method for implementing a logical router of a logical network. The method receives a configuration for a first logical router. The configuration includes a static route for the first logical router. The method defines several routing components with separate routing tables for the logical router. The method adds a first route, having a first static route type, for the static route to the routing tables of at least a first subset of the routing components. Based on the connection of a second logical router to the first logical router, adding a second route, having a second static route type, to the routing tables of at least a second subset of the routing components.

Abstract: Provided is a method for analyzing the expansive stress and expansive strain of tunnel surrounding rock, including: (1) determining the surrounding rock state of the tunnel surrounding rock before expansion and the surrounding rock state after expansion; (2) according to the determined state of the surrounding rock, determining the expansive stress and expansive strain of the tunnel surrounding rock before expansion, and determining the expansive stress and expansive strain of the tunnel surrounding rock after expansion; (3) according to the surrounding rock state of the tunnel surrounding rock after expansion, determining the expansive deformation radius of the tunnel surrounding rock, so as to determine the expansive deformation displacement of the tunnel surrounding rock.

Abstract: A battery apparatus includes at least two battery units. Each of the battery units includes at least two batteries. A heat insulating pad is disposed between the adjacent two battery units, and at least a pair of the adjacent two batteries belonging to a same battery unit contact each other with largest surfaces of the batteries.

Abstract: A new set of bench-stable fluoroalkylphosphines that directly convert C—H bonds in pyridine building blocks, drug-like fragments, and pharmaceuticals, into fluoroalkyl derivatives. No pre-installed functional groups or directing motifs are required. The reaction tolerates a variety of sterically and electronically distinct pyridines and is exclusively selective for the 4-position in most cases. The reaction proceeds via initial phosphonium salt formation followed by sp2-sp3 phosphorus ligand-coupling, an underdeveloped manifold for C—C bond formation.

Abstract: An external wideband antenna and a wireless communication device are provided in the disclosure. The external wideband antenna includes a radio frequency (RF) coaxial cable, and a first antenna body and a second antenna body which are electrically connected with the RF coaxial cable respectively, where an outer contour of the first antenna body and an outer contour of the second antenna body cooperate to define a tapered slot. In the external wideband antenna provided the disclosure, the outer contour of the first antenna body and the outer contour of the second antenna body cooperate to define the tapered slot, which facilitates generation of a strong coupling current, and in turn a broadening of antenna bandwidth.

Abstract: A power supply system and a control method and control device thereof are provided. The power supply system includes a first power supply device, a heat-dissipation unit, a second power supply device, and a control device. The control device is configured to confirm whether each battery pack in the first power supply device experiences thermal runaway, and control the first power supply device to supply power to the heat-dissipation unit when no battery pack in the first power supply device experiences thermal runaway, so that the heat-dissipation unit dissipates heat from the first power supply device; and control a battery pack not experiencing thermal runaway in the first power supply device and/or the second power supply device to supply power to the heat-dissipation unit when a battery pack in the first power supply device experiences thermal runaway, so that the heat-dissipation unit dissipates heat from the first power supply device.

Abstract: The disclosure relates a battery technology field, and in particular, relates to a battery pack. The battery pack includes a battery array and a liquid cooling tube. The battery array includes at least two batteries, and the batteries are arranged in a first direction. The liquid cooling tube is disposed on a surface of the battery array and is configured to dissipate heat for the batteries. The liquid cooling tube includes cooling portions, and the cooling portions are portions of an orthographic projection of the liquid cooling tube on the battery array. Orthographic projections of the cooling portions on the battery array are cooling regions. In the battery array, at least one of the batteries is located outside a range of the cooling portions.

Abstract: A battery pack includes a battery column and a liquid cooling tube. The battery column includes at least two batteries, and the batteries are arranged in a first direction. The liquid cooling tube is disposed on a surface of the battery column and is configured to dissipate heat for the batteries. The liquid cooling tube includes cooling portions, and the cooling portions are portions having orthographic projections on the battery column. The orthographic projections of the cooling portions on the battery column are cooling regions. The cooling portions extend in a second direction, and the second direction is not parallel to the first direction.

Abstract: The invention discloses a method for analyzing the expansive stress and expansive strain of tunnel surrounding rock, including: (1) determining the surrounding rock state of the tunnel surrounding rock before expansion and the surrounding rock state after expansion; (2) according to the determined state of the surrounding rock, determining the expansive stress and expansive strain of the tunnel surrounding rock before expansion, and determining the expansive stress and expansive strain of the tunnel surrounding rock after expansion; (3) according to the surrounding rock state of the tunnel surrounding rock after expansion, the expansive deformation radius of the tunnel surrounding rock is determined, so as to determine the expansive deformation displacement of the tunnel surrounding rock.

Abstract: The invention discloses a method for analyzing the constitutive relationship of confined rock expansion, including: (1) determining parameters that affect rock expansive properties, wherein the parameters comprise category, density, and water content; (2) establishing an expression of the relationship between the parameters and rock expansive capacity; (3) establishing an expression of the relationship among the rock expansive capacity, rock expansive stress and rock expansive strain; and (4) determining an expression of the relationship among the parameters, the rock expansive stress and the rock expansive strain according to the rock expansive capacity. The present invention introduces parameters comprising category, density, and water content that affect the rock expansive properties into the analysis of rock expansive stress and rock expansive strain, which can truly reflect the variation of rock expansive stress and rock expansive strain, and can achieve quantized calculation of the rock expansive state.

Abstract: A device of correcting duty cycle includes: a duty cycle correcting circuit, a controller of the duty cycle correcting circuit and a duty cycle detecting circuit. The duty cycle correcting circuit generates a pair of phase-shifting clocks in accordance with a pair of complementary clocks and regenerates a regenerated clock in accordance with the pair of phase-shifting clocks. The controller of the duty cycle correcting circuit couples to the duty cycle correcting circuit. The duty cycle detecting circuit couples to the duty cycle correcting circuit and the controller of the duty cycle correcting circuit, and generates a detecting output to the controller of the duty cycle correcting circuit in accordance with a current duty cycle of the regenerated clock. The controller of the duty cycle correcting circuit controls the duty cycle correcting circuit in accordance with the detecting output to adjust the pair of phase-shifting clocks.

Abstract: A device (e.g., an application-specific integrated circuit chip) includes a memory module processing unit and an interface. The memory module processing unit is configured to receive an instruction to obtain values stored in one or more memory components and process the obtained values to return a processed result. The memory module processing unit is also configured to store the obtained values in a cache based on one or more criteria. The memory module processing unit is configured to be included on a computer memory module configured to be installed in a computer system. The interface is configured to communicate with the one or more memory components included on the computer memory module.