Patents by Inventor Yang LIN

Yang LIN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250223289
    Abstract: Disclosed are small molecule inhibitors of ?v?6 integrin, and methods of using them to treat a number of specific diseases or conditions.
    Type: Application
    Filed: October 11, 2024
    Publication date: July 10, 2025
    Inventors: Bryce A. Harrison, Matthew G. Bursavich, Aleksey I. Gerasyuto, Kristopher N. Hahn, Kyle D. Konze, Fu-Yang Lin, Blaise S. Lippa, Alexey A. Lugovskoy, Bruce N. Rogers, Mats A. Svensson, Dawn M. Troast
  • Publication number: 20250212431
    Abstract: A semiconductor device includes an emitter, a first base encircling the emitter, a first collector encircling the emitter and the first base, a second base encircling the emitter, the first base and the first collector, and a second collector encircling the second base. The first collector is separated from the emitter by the first base, and the second collector is separated from the emitter, the first base and the first collector by the second base. The emitter, the first base, the first collector, the second base and the second collector form a concentric pattern.
    Type: Application
    Filed: December 25, 2023
    Publication date: June 26, 2025
    Inventors: TUNG-YANG LIN, HUNG-CHIH TSAI, RUEY-HSIN LIU
  • Patent number: 12320936
    Abstract: In the present invention, an earthquake detection system based on the combination configuration of a free field and remote signal source is provided. The earthquake detection system includes: a host; a main sensor arranged in a free field and connected to the host; and a plurality of backup sensors, which are remotely arranged with respect to the main sensor, wherein each of the backup is connected to the host via the internet and transmits a remote signal to the host so as to avoid misjudging the occurrence of earthquakes because of unnatural factors, and prevent the vibration caused by human activities from interfering with the detector. The earthquake detection system achieves the effect of verification through a plurality of sensors installed in different positions.
    Type: Grant
    Filed: January 19, 2023
    Date of Patent: June 3, 2025
    Assignee: P-Waver Inc.
    Inventors: Hung-Wei Chiang, Pei-Yang Lin, Hsiu-Hsien Wang
  • Patent number: 12319724
    Abstract: The present disclosure relates to IL2 agonists with improved therapeutic profiles.
    Type: Grant
    Filed: June 17, 2022
    Date of Patent: June 3, 2025
    Assignee: Regeneron Pharmaceuticals, Inc.
    Inventors: Jiaxi Wu, Tong Zhang, Maria del Pilar Molina-Portela, Eric Smith, Chia-Yang Lin, Thomas Craig Meagher
  • Publication number: 20250166296
    Abstract: A moving-object elimination method for 3D modeling, including the following steps. The method includes detecting a plurality of feature points in each original image in a sequence of original images through a feature point detection process. The method includes detecting a plurality of feature points in each original image through a feature point detection process. The method includes dividing each original image into a plurality of regions through a region segmentation process. The method includes determining a target region and one or more non-target regions from the regions of each original image. The method includes determining whether each of the non-target regions of two consecutive frames is a moving-object region through a feature-point matching process based on the feature points. The method includes replacing, for each original image, the non-target regions determined as moving-object regions with a featureless region, to obtain a sequence of static images.
    Type: Application
    Filed: September 25, 2024
    Publication date: May 22, 2025
    Inventors: Ting-Wei CHANG, Kual-Zheng LEE, Tzu-Yang LIN
  • Publication number: 20250151850
    Abstract: A heel cup applied in a shoe is provided. The heel cup includes an inner surface and an outer surface. Each of the inner surface and the outer surface is a curved surface. The heel cup includes a first part and a second part connected along a longitudinal direction. The heel cup has a cross-section along the longitudinal direction, each cross-section has a shape of an arc. Each cross-section includes an upper arc and a lower arc connected along the longitudinal direction. When viewed from a side where the inner surface of the heel cup is located, the inner surface of the first part is convex, and the inner surface of the second part is concave. The upper arc has a first bending amplitude, and the lower arc has a second bending amplitude, wherein the first bending amplitude is greater than or equal to the second bending amplitude.
    Type: Application
    Filed: January 14, 2025
    Publication date: May 15, 2025
    Inventors: Hao He, Changsheng Cao, Yang Lin, Hongwei Liu, Yong Yang, Jian Li, Zhengqiang Zhao
  • Publication number: 20250147221
    Abstract: A light-guide optical element and a method for manufacturing the same, includes: a coating step including forming at least one functional coating on a surface of a substrate, and cutting the substrate to form at least one optical coating strip; a mounting step including placing at least one optical coating strip in a storage space of a first substrate; an assembling step including combining a second substrate corresponding to the first substrate with the first substrate, so that the at least one optical coating strip is positioned between the first substrate and the second substrate, forming a semi-finished product; and a cutting step including cutting the semi-finished product into at least one finished light-guide optical element, and the at least one finished light-guide optical element includes the at least one optical coating strip.
    Type: Application
    Filed: November 2, 2023
    Publication date: May 8, 2025
    Inventors: Yung-Chun Wang, Yung-Sheng Cheng, Hsang-Yang Lin, Sen-Tsung Hsiao
  • Patent number: 12292684
    Abstract: A method is provided including forming a first layer over a substrate and forming an adhesion layer over the first layer. The adhesion layer has a composition including an epoxy group. A photoresist layer is formed directly on the adhesion layer. A portion of the photoresist layer is exposed to a radiation source. The composition of the adhesion layer and the exposed portion of the photoresist layer cross-link using the epoxy group. Thee photoresist layer is then developed (e.g., by a negative tone developer) to form a photoresist pattern feature, which may overlie the formed cross-linked region.
    Type: Grant
    Filed: December 7, 2020
    Date of Patent: May 6, 2025
    Assignee: TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD.
    Inventors: Chen-Yu Liu, Tzu-Yang Lin, Ya-Ching Chang, Ching-Yu Chang, Chin-Hsiang Lin
  • Patent number: 12285441
    Abstract: The present disclosure is related to a conjugate of an active drug and a glycosaminoglycan, such as hyaluronic acid (HA). For example, the active drug can be lenalidomide, nimesulide, or gemcitabine. The conjugate of the present disclosure is useful in the treatment of certain cancers.
    Type: Grant
    Filed: December 15, 2021
    Date of Patent: April 29, 2025
    Assignee: Holy Stone Healthcare Co., Ltd.
    Inventor: Hua-Yang Lin
  • Patent number: 12281133
    Abstract: Disclosed herein are hyaluronic acid (HA)-nimesulide conjugates having one or two disaccharide units.
    Type: Grant
    Filed: March 20, 2023
    Date of Patent: April 22, 2025
    Assignee: Aihol Corporation
    Inventor: Hua-Yang Lin
  • Patent number: 12274747
    Abstract: The present invention provides compositions and methods for treating cancer and inhibiting cytokine release syndrome (CRS). The methods of the present invention comprise administering to a subject in need thereof a therapeutically effective amount of a CD40 antagonist or a CAR-T cell expressing a CD40 antagonist in combination with a therapeutically effective amount of a CD3 multispecific antigen binding molecule.
    Type: Grant
    Filed: January 28, 2022
    Date of Patent: April 15, 2025
    Assignee: Regeneron Pharmaceuticals, Inc.
    Inventors: Kara Olson, Olga Sineshchekova, Eric Smith, Chia-Yang Lin
  • Publication number: 20250109207
    Abstract: The present disclosure relates to chimeric heavy chain constant domains having reduced effector function. Also disclosed are recombinant polypeptides comprising such chimeric heavy chain constant domains, including antibodies such as multispecific antibodies, fusion proteins, and other recombinant proteins. Nucleic acids encoding such recombinant polypeptides are also disclosed, as well as cells expressing such recombinant polypeptides and pharmaceutical compositions comprising such recombinant polypeptides.
    Type: Application
    Filed: April 20, 2023
    Publication date: April 3, 2025
    Applicant: Regeneron Pharmaceuticals, Inc.
    Inventors: Naga Suhasini AVVARU, Samuel DAVIS, Chia-Yang LIN, Yang SHEN
  • Publication number: 20250109194
    Abstract: Antigen binding molecules (ABMs) comprising Fab domains in non-native configurations, ABM conjugates comprising the ABMs and cytotoxic or cytostatic agents, pharmaceutical compositions containing the ABMs and ABM conjugates, methods of using the ABMs, ABM conjugates and pharmaceutical compositions for treating cancer, nucleic acids encoding the ABMs, cells engineered to express the ABMs, and methods of producing ABMs.
    Type: Application
    Filed: December 11, 2024
    Publication date: April 3, 2025
    Applicant: Regeneron Pharmaceuticals, Inc.
    Inventors: Tong ZHANG, Samuel DAVIS, Chia-Yang LIN, Eric SMITH, Erica PYLES, Michael ROSCONI, Nina LIU, Supriya PATEL, Andrew J. MURPHY
  • Patent number: 12255857
    Abstract: In some embodiments, an electronic device displays a plurality of content items in a messaging conversation. In some embodiments, the electronic device displays user interfaces associated with one or more content items in a messaging conversation.
    Type: Grant
    Filed: January 29, 2024
    Date of Patent: March 18, 2025
    Assignee: Apple Inc.
    Inventors: Zheng Xuan Hong, Chia Yang Lin, Chanaka G. Karunamuni, Nicole R. Ryan, Graham R. Clarke
  • Patent number: 12255091
    Abstract: Semiconductor processing apparatuses and methods are provided in which an electrostatic discharge (ESD) prevention layer is utilized to prevent or reduce ESD events from occurring between a semiconductor wafer and one or more components of the apparatuses. In some embodiments, a semiconductor processing apparatus includes a wafer handling structure that is configured to support a semiconductor wafer during processing of the semiconductor wafer. The apparatus further includes an ESD prevention layer on the wafer handling structure. The ESD prevention layer includes a first material and a second material, and the second material has an electrical conductivity that is greater than an electrical conductivity of the first material.
    Type: Grant
    Filed: November 21, 2023
    Date of Patent: March 18, 2025
    Assignee: Taiwan Semiconductor Manufacturing Co., Ltd.
    Inventors: Tsai-Hao Hung, Ping-Cheng Ko, Tzu-Yang Lin, Fang-Yu Liu, Cheng-Han Wu
  • Publication number: 20250079849
    Abstract: The embodiment of the present disclosure provides a photovoltaic component control device including at least one bypass module configured to connect in parallel to at least one photovoltaic component; a driving circuit configured to drive the at least one bypass module to operate under control of a controller; a power supply module configured to obtain energy from the at least one photovoltaic component and output the energy to the controller in a case that the at least one photovoltaic component operates normally and the at least one photovoltaic component is bypassed; the controller configured to control an ON state of the at least one bypass module to control whether the at least one photovoltaic component is in a bypass mode. The energy consumption of the control device is greatly reduced, a problem of voltage stress is solved, and the safety performance of the bypass-type control device is improved.
    Type: Application
    Filed: May 1, 2024
    Publication date: March 6, 2025
    Applicant: SUZHOU UKT NEW ENERGY TECHNOLOGY CO., LTD.
    Inventors: Xiaojun Tai, Yichi Zhang, Huiming Cai, Yang Lin, Liang Zhou, Youhua Huang
  • Patent number: 12240907
    Abstract: Multispecific binding molecules (MBMs) comprising an N-terminal scFv, a first Fab and a second Fab, MBM conjugates comprising the MBMs and cytotoxic or cytostatic agents, pharmaceutical compositions containing the MBMs and MBM conjugates, methods of using the MBMs, MBM conjugates and pharmaceutical compositions for treating cancer, nucleic acids encoding the MBMs, cells engineered to express the MBMs, and methods of producing MBMs.
    Type: Grant
    Filed: November 4, 2020
    Date of Patent: March 4, 2025
    Assignee: Regeneron Pharmaceuticals, Inc.
    Inventors: Yang Shen, Ann-Hwee Lee, Yan Yang, Chia-Yang Lin
  • Patent number: 12240908
    Abstract: Multispecific binding molecules (MBMs) comprising an N-terminal scFv, a first Fab and a second Fab, MBM conjugates comprising the MBMs and cytotoxic or cytostatic agents, pharmaceutical compositions containing the MBMs and MBM conjugates, methods of using the MBMs, MBM conjugates and pharmaceutical compositions for treating cancer, nucleic acids encoding the MBMs, cells engineered to express the MBMs, and methods of producing MBMs.
    Type: Grant
    Filed: April 22, 2022
    Date of Patent: March 4, 2025
    Assignee: Regeneron Pharmaceuticals, Inc.
    Inventors: Yang Shen, Ann-Hwee Lee, Yan Yang, Chia-Yang Lin
  • Patent number: D1071506
    Type: Grant
    Filed: October 8, 2023
    Date of Patent: April 22, 2025
    Inventors: Yang Lin, Hongwei Liu
  • Patent number: D1079220
    Type: Grant
    Filed: January 7, 2025
    Date of Patent: June 17, 2025
    Inventors: Hao He, Xin Gu, Changsheng Cao, Yang Lin