Abstract: Disclosed is a die-bonding method which provides a target substrate having a circuit structure with multiple electrical contacts and multiple semiconductor elements each semiconductor element having a pair of electrodes, arranges the multiple semiconductor elements on the target substrate with the pair of electrodes of each semiconductor element aligned with two corresponding electrical contacts of the target substrate, and applies at least one energy beam to join and electrically connect the at least one pair of electrodes of every at least one of the multiple semiconductor elements and the corresponding electrical contacts aligned therewith in a heating cycle by heat carried by the at least one energy beam in the heating cycle. The die-bonding method delivers scattering heated dots over the target substrate to avoid warpage of PCB and ensures high bonding strength between the semiconductor elements and the circuit structure of the target substrate.

Abstract: A supporting assembly configured to fix chassis of electronic device to fixing bracket. Supporting assembly includes plate body, cushion, fastener and spacer. Plate body includes mounting hole and wall surface forming mounting hole, and plate body is configured to be fixed to chassis of electronic device. Cushion is disposed through mounting hole and includes opening. Fastener is disposed through opening of cushion. A side of fastener is configured to be fixed to fixing bracket, and cushion is clamped between another side of fastener and fixing bracket so as to be compressed. Spacer is disposed in mounting hole and located between wall surface of plate body and cushion. Hardness of spacer is greater than hardness of cushion.

Abstract: A supporting assembly configured to fix a casing of an electronic device to a chassis and including a plate body, a cushioning component and a fastener. The plate body includes a mounting hole. The cushioning component is disposed through the mounting hole. The cushioning component includes a through hole. The fastener is disposed through the through hole of the cushioning component. A side of the fastener is configured to be fixed to the chassis, and the cushioning component is compressed by another side of the fastener and the chassis.

Abstract: A method for manufacturing an amorphous multielement metal oxide hydroxide film includes: A liquid mixture is formed by dissolving an oxidizing agent selected from a group consisting of potassium permanganate, potassium chromate, potassium dichromate and potassium ferrate, and a reducing agent in a solvent. The oxidizing agent forms an oxometallate anion having a first metal atom with a first valence number. The reducing agent forms a metal cation having a second metal atom with a third valence number. An amorphous multielement metal oxide hydroxide film is deposited on a substrate by soaking the substrate in the liquid mixture. The amorphous multielement metal oxide hydroxide film includes a multielement metal oxide hydroxide having the first metal atom with a second valence smaller than the first valence number and the second metal atom with a fourth valence number larger than the third valence number.

Abstract: Methods of determining one or more ratios of chemokines in gingival crevicular fluid of an individual selected from the group consisting of: MIF:MIP1a, M1F:CXCL1; MIF:CXCL5; MIF:CXCL8; M1F:CXCL2; and MIF:CXCL6 and methods of identifying an individual as having gingivitis comprising determining one or more ratios of the chemokines in gingival crevicular fluid are disclosed. Methods of treating individuals who are identified as having gingivitis by determining one or more ratios of the chemokines in gingival crevicular fluid are disclosed. Also disclosed are methods of monitoring the treatment individuals who have gingivitis.

Abstract: A method may include receiving, from a software application, pre-signup data of a user, embedding the pre-signup data to obtain a pre-signup data vector, generating, by applying a topic model to the pre-signup data vector, a pre-signup topic vector, receiving action descriptions of actions of the software application, embedding the action descriptions to obtain action description vectors, generating, by applying the topic model to the action description vectors, action description topic vectors, generating scores by multiplying the pre-signup topic vector and the action description topic vectors, and recommending, to the user and using the scores, an action.

Abstract: A radio system includes a radio voice terminal, a relay server, a command center and a radio network gateway. The radio network gateway includes a communication module in communication with the relay server; a radio voice control module in communication with the first radio voice terminal, receiving a radio voice signal from the first radio voice terminal; and a processing module in communication with the communication module and the radio voice control module, converting the radio voice signal into a digital voice file, executing a voice recognition process to extract at least one keyword from the digital voice file, and transmitting the at least one keyword to the relay server through the communication module.

Abstract: The invention provides eTEC linked glycoconjugates comprising a saccharide covalently conjugated to a carrier protein through a (2-((2-oxoethyl)thio)ethyl)carbamate (eTEC) spacer, immunogenic compositions comprising such glycoconjugates, and methods for the preparation and use of such glycoconjugates and immunogenic compositions.

Abstract: Some embodiments of the present disclosure relate to a roofing system. In some embodiments, the roofing system includes a roofing membrane, which may include a cap, a scrim, and a core. In some embodiments, the roofing system may also include an adhesive film, which may include a first adhesive layer adhered to the roofing membrane, a second adhesive layer configured to adhere the roofing membrane to a roofing substrate, and a barrier layer positioned between the first and second adhesive layers. Methods of manufacturing roofing systems are also disclosed.

Abstract: An oral biology model which comprises biofilm, oral epithelial tissue and a suspension of neutrophil-like cells in media is disclosed. The biofilm, which comprises oral bacteria, is produced by culturing oral bacteria on a solid substrate. The oral epithelial tissue may be gingival epithelial tissue to model the gingival crevice or buccal epithelial tissue to model the oral check. The suspension of neutrophil-like cells in media comprises neutrophil-like cells that are differentiated HL60 cells induced to a neutrophil-like phenotype by treatment with retinoic acid. Methods of using the oral biology model to test and compare compounds and formulations or to screen compounds and formulations for their effect on release of inflammatory signals, their effect on biofilm and oral bacteria and/or their effect on the cellular components are disclosed.

Abstract: A device and a method for detecting tumor mutation burden (TMB) based on capture sequencing are disclosed. The device includes: a panel design module configured to uniformly add population single-nucleotide polymorphism (SNP) sites to a genome and screen out gene regions that show the highest consistency with whole exome sequencing (WES); a data acquisition module configured to acquire tissue and plasma samples of a target object and acquire sequencing data of the samples; an alignment module configured to align the sequencing data with a reference genome to acquire mutation data results; a somatic mutation analysis module configured to perform somatic analysis on the mutation data results to obtain somatic mutation results; a filtering module configured to remove unreal mutation sites from the somatic mutation results; and a calculation module configured to calculate the TMB.

Abstract: Nail sealable materials comprising a matrix material and bentonite embedded within the matrix material are described herein in accordance with non-limiting embodiments of the present disclosure. In some embodiments, the nail sealable material comprises a sufficient amount of bentonite, such that the nail sealable material passes ASTM D1970 at a specified nail sealable material test thickness. Some embodiments relate to systems and methods utilizing the nail sealable materials described herein.

Abstract: A coin dispenser is disclosed to use a dialing rod of a dialing device of a coin dispensing unit to push one side of the peripheral edge of one metal coin so that the other side of the peripheral edge of the metal coin will push two coin-stopping columns of one spring plate of the coin dispensing unit, causing the two coin-stopping columns to slide along the peripheral edge of the metal coin, and thus, when the metal coin crosses two coin-stopping columns, the metal coin is sent out of the coin outlet, achieving the effect of dispensing one metal coin at one time.

Abstract: A high-voltage semiconductor device includes a substrate, a first insulating structure, a gate, a drain region, a source region and a doped region. The substrate has a first conductive type, and the first insulating structure is disposed on the substrate. The drain region and the source region are disposed in the substrate. The source region has a first portion and a second portion. The first portion has the second conductive type and the second portion has the first conductive type. The gate is disposed on the substrate, between the source region and the drain region to partially cover a side of the first insulating structure. The doped region is disposed in the substrate and has a first doped region and a second doped region, and the first doped region and the second doped region both include the first conductive type and separately disposed under the first insulating structure.

Abstract: A Fe—Ni based alloy comprising, in weight percent: Ni 30-35; Cr 12-14; Al 3-5; Ti 0-2; Ta 2-8; C<=0.05; B<=0.005; Zr<=0.2; Si<0.5; where Cr/(Cr+Fe+Ni)=0.125-0.145; Al/(Al+Ti+Ta)=0.15-0.5; and Fe?Ni; balance Fe, the alloy having a face-centered cubic (fcc) matrix with from 25 to 30 vol. % of L12-type ??-Ni3M (M=Al, Ta, Ti and mixtures thereof) precipitates.

Abstract: Provided is an antimicrobial peptide Sparamosin from Scylla paramamosain. The Sparamosin mature peptide and its functional domain Sparamosin26-54 were synthesized by solid-phase synthesis with a purity of over 95%. Both Sparamosin and Sparamosin26-54 exhibit strong antimicrobial activity. More importantly, Sparamosin26-54 has strong antifungal activity and could inhibit the growth of a variety of yeasts and filamentous fungi. Based on the potent antimicrobial activities of Sparamosin and Sparamosin26-54, both peptides could be developed as alternatives for conventional antibiotics, antimicrobial agents, feed additives in aquaculture and livestock, preservatives, and mold inhibitors.

Abstract: An avalanche-protected field effect transistor includes, within a semiconductor substrate, a body semiconductor layer and a doped body contact region having a doping of a first conductivity type, and a source region a drain region having a doping of a second conductivity type. A buried first-conductivity-type well may be located within the semiconductor substrate. The buried first-conductivity-type well underlies, and has an areal overlap in a plan view with, the drain region, and is vertically spaced apart from the drain region, and has a higher atomic concentration of dopants of the first conductivity type than the body semiconductor layer. The configuration of the field effect transistor induces more than 90% of impact ionization electrical charges during avalanche breakdown to flow from the source region, to pass through the buried first-conductivity-type well, and to impinge on a bottom surface of the drain region.

Abstract: The present application belongs to the field of biotechnology, and particularly relates to preparation and use of soluble Tim-3 recombinant protein and a mutant protein thereof. The soluble Tim-3 recombinant protein is used to prepare a drug with the function of regulating monocytes or a drug with the function of enhancing tumor immune response, and the amino acid sequence of the soluble Tim-3 recombinant protein is as shown in SEQ ID NO: 1. In addition, the present application further provides the mutant proteins of the sTim-3 recombinant protein and preparation and use of the mutant protein. The mutant recombinant protein is obtained by screening through a directed evolutionary technology, with the function of regulating monocytes or the function of enhancing tumor immune response, and combines with a host codon optimization method to improve the expression efficiency.

Abstract: The invention generally relates to a carbon-based boron removal medium with hydroxyl group and amine group, and in particular, to a method for forming the carbon-based boron removal medium. In various embodiments, nitrogen-doped (“N-doped”) graphene oxide is synthesized by a simple two-step process: (1) oxidation of graphite to graphene oxide, and (2) nitrogen-doping (“N-doping”) the graphene oxide to form the amine group. The resultant N-doped graphene oxide can efficiently remove boron from aqueous solutions. The invention also generally relates to a boron sensing medium and its use in conductometric measurement techniques to detect and measure the amount of boron present in aqueous solutions.

Abstract: A tool for combining common processes shared by at least two or more sub-queries within a query is provided. The tool determines whether one or more sub set relationships are shared between the at least two or more sub-queries. Responsive to a determination that one or more sub set relationships are shared between the at least two or more sub-queries, the tool determines an order class for the at least two or more sub-queries based on the one or more sub set relationships, wherein determining the order class includes transforming the query to include one or more differing aspects within the single shared common process, with the one or more differing aspects arranged based, at least in part, on a query style, a query type, and a query function. Responsive to determining an access path for the query, the tool executes the access path during run-time for data accessing.