Abstract: Methods are disclosed for determining the minimal residual cancer status of an individual utilizing assays that detect cancer associated genetic variation in extracellular DNA. The disclosed methods provide for personalized cancer detection based on the genetic profile of solid cancer tissue of an individual under study. The disclosed methods further provide for noise reduction in the sequencing of extracellular DNA and reduced false positive rates in minimal residual cancer status determination.

Abstract: The invention relates to activated Streptococcus pneumoniae serotype 10A, 22F or 33F polysaccharides and processes for their preparation. The invention also relates to immunogenic conjugates comprising Streptococcus pneumoniae serotype 10A, 22F or 33F polysaccharides covalently linked to a carrier protein, processes for their preparation and immunogenic compositions and vaccines comprising them.

Abstract: The present disclosure discloses an antimicrobial peptide Scyreprocin of Scylla paramamosain and a method thereof, wherein an amino acid sequence of the antimicrobial peptide Scyreprocin comprises a sequence shown in SEQ ID NO 01, and the antimicrobial peptide is expressed and purified by using genetic engineering technology. The recombinant antimicrobial peptide Scyreprocin has advantages of wide antimicrobial spectrum, good antimicrobial effect, and rapid germicidal rate, shows great application significance, and has good application in preparation of antimicrobial agents. The recombinant antimicrobial peptide Scyreprocin has no cytotoxicity to mouse hepatocytes AML12, human liver cells L02, and can be safely used for medical treatment or can be used as a feed composition.

Abstract: A method for forming a semiconductor structure includes providing a substrate including a first region with a first gate structure and a second region with a second gate structure. First to third dielectric layers are formed on the substrate. The third dielectric layer is patterned to form a first portion in the first region and a second portion in the second region. The second region is covered and at least a portion of the first portion is removed to form a first mask. The second dielectric layer is pattern by using the first mask and the second portion as the second mask to expose a portion of the first dielectric layer. The portion of the first dielectric layer is removed to form a first stacked spacer on the first gate structure and a second stacked spacer on the second gate structure.

Abstract: An avalanche-protected field effect transistor includes, within a semiconductor substrate, a body semiconductor layer and a doped body contact region having a doping of a first conductivity type, and a source region a drain region having a doping of a second conductivity type. A buried first-conductivity-type well may be located within the semiconductor substrate. The buried first-conductivity-type well underlies, and has an areal overlap in a plan view with, the drain region, and is vertically spaced apart from the drain region, and has a higher atomic concentration of dopants of the first conductivity type than the body semiconductor layer. The configuration of the field effect transistor induces more than 90% of impact ionization electrical charges during avalanche breakdown to flow from the source region, to pass through the buried first-conductivity-type well, and to impinge on a bottom surface of the drain region.

Abstract: Some embodiments of the present disclosure relate to a roofing system. In some embodiments, the roofing system includes a first roofing material, wherein the first roofing material comprises a top surface and a bottom surface. In some embodiments, the top surface of the first roofing material comprises a nail zone with a plurality of fines. In some embodiments, the roofing system includes a second roofing material, wherein the second roofing material comprises a top surface and a bottom surface. In some embodiments, the bottom surface of the second roofing material comprises a plurality of fines. In some embodiments, the roofing system comprises and a patterned adhesive, which directly contacts at least a portion of the plurality of fines in the nail zone and at least a portion of the plurality of fines on the bottom surface of the second roofing material.

Abstract: A method includes obtaining a roofing membrane. A first layer of the roofing membrane is applied along a length of a roofing substrate covering a first portion of the roofing substrate. At least a first edge of the first layer is fastened to the roofing substrate. A second layer of the roofing membrane is applied over the first layer along the length of the roofing substrate such that a first edge of the second layer overlies the second edge of the first layer. The first edge of the second layer and the second edge of the first layer are fastened to the roofing substrate using a second fastener in a fastening zone along the length the roofing substrate. The second layer is reoriented such that the second layer overlies the fastening zone and covers a second portion of the roofing substrate adjacent the first portion of the roofing substrate.

Abstract: A radio system includes a radio voice terminal, a relay server, a command center and a radio network gateway. The radio network gateway includes a communication module in communication with the relay server; a radio voice control module in communication with the first radio voice terminal, receiving a radio voice signal from the first radio voice terminal; and a processing module in communication with the communication module and the radio voice control module, converting the radio voice signal into a digital voice file, executing a voice recognition process to extract at least one keyword from the digital voice file, and transmitting the at least one keyword to the relay server through the communication module.

Abstract: Disclosed are a method and system for correcting the precision of a magnetic levitation train traction system position control ring. The precision correction method comprises: step A, a speed measuring system collecting position-related information of a train; step B, sending the position-related information to a traction system through a signal system; and step C, the traction system carrying out closed-loop control on the position of the train according to the position-related information. The method further comprises step A1 before step A: checking the time for the speed measuring system, the signal system and the traction system, and adding timestamp information. According to the correcting method and system, the time is checked for a speed measuring system, a signal system and a traction system, and timestamp information is added, such that the influences of a delay and periodic random shaking are overcome, and the requirement of traction control of a medium-high speed magnetic levitation train is met.

Abstract: Disclosed is a die-bonding method which provides a target substrate having a circuit structure with multiple electrical contacts and multiple semiconductor elements each semiconductor element having a pair of electrodes, arranges the multiple semiconductor elements on the target substrate with the pair of electrodes of each semiconductor element aligned with two corresponding electrical contacts of the target substrate, and applies at least one energy beam to join and electrically connect the at least one pair of electrodes of every at least one of the multiple semiconductor elements and the corresponding electrical contacts aligned therewith in a heating cycle by heat carried by the at least one energy beam in the heating cycle. The die-bonding method delivers scattering heated dots over the target substrate to avoid warpage of PCB and ensures high bonding strength between the semiconductor elements and the circuit structure of the target substrate.

Abstract: A peptide Scyreprocin of Scylla paramamosain, an amino acid sequence of the peptide Scyreprocin is SEQ ID NO 01.

Abstract: A bearing assembly configured to be disposed on casing of electronic device and including plate body, first damping component, second damping component, first fastener and second fastener. The plate body includes first mounting hole and second mounting hole. The first damping component is disposed in the first mounting hole. The first damping component includes first hole. The second damping component is disposed in the second mounting hole. The second damping component includes second hole. The first fastener is disposed in the first hole of the first damping component and configured to be fixed to the casing of the electronic device. The second fastener is disposed in the second hole of the second damping component and configured to be fixed to the casing of the electronic device. A hardness of the first damping component is greater than a hardness of the second damping component.

Abstract: Disclosed are a display module, a display device and a viewing-angle switching method. The display module includes a backlight module, a display panel, a lower polarizer sheet, a viewing-angle switching element and a transparent cover plate; the viewing-angle switching element and the transparent cover plate are arranged between the display panel and the lower polarizer sheet, and the transparent cover plate is arranged on a side of the viewing-angle switching element that is close to the lower polarizer sheet; the backlight module is configured to supply light that meets a preset condition, the viewing-angle switching element is configured to switch viewing-angle modes of the display module; the viewing-angle modes include; a first viewing-angle mode and a second viewing-angle mode; and a viewing-angle range of the first viewing-angle mode is smaller than a viewing angle range of the second viewing-angle mode.

Abstract: An avalanche-protected field effect transistor includes, within a semiconductor substrate, a body semiconductor layer and a doped body contact region having a doping of a first conductivity type, and a source region a drain region having a doping of a second conductivity type. A buried first-conductivity-type well may be located within the semiconductor substrate. The buried first-conductivity-type well underlies, and has an areal overlap in a plan view with, the drain region, and is vertically spaced apart from the drain region, and has a higher atomic concentration of dopants of the first conductivity type than the body semiconductor layer. The configuration of the field effect transistor induces more than 90% of impact ionization electrical charges during avalanche breakdown to flow from the source region, to pass through the buried first-conductivity-type well, and to impinge on a bottom surface of the drain region.

Abstract: Some embodiments of the present disclosure relate to a roofing system. In some embodiments, the roofing system includes a roofing membrane, which may include a cap, a scrim, and a core. In some embodiments, the roofing system may also include an adhesive film, which may include a first adhesive layer adhered to the roofing membrane, a second adhesive layer configured to adhere the roofing membrane to a roofing substrate, and a barrier layer positioned between the first and second adhesive layers. Methods of manufacturing roofing systems are also disclosed.

Abstract: The invention relates to activated Streptococcus pneumoniae serotype 10A, 22F or 33F polysaccharides and processes for their preparation. The invention also relates to immunogenic conjugates comprising Streptococcus pneumoniae serotype 10A, 22F or 33F polysaccharides covalently linked to a carrier protein, processes for their preparation and immunogenic compositions and vaccines comprising them.

Abstract: The present invention is directed to a depot composition for sustained release delivery of buprenorphine with enhanced stability and bioavailability. The composition is an injectable, low viscosity liquid and can form a depot in situ capable of delivering therapeutic level of buprenorphine over a period of time from one week to 3 months.

Abstract: Distance measuring is disclosed. In one example, a distance measuring device includes a ToF (time of flight) sensor, a distance calculation unit, a mode switching unit, and an estimation unit. The ToF sensor has a sensor clock that controls a photographing timing. The sensor clock is a device-specific clock different from a light source clock that controls a modulation frequency of a light emission pulse of a light source. The ToF sensor performs photographing by reflecting, on a surface of an object, emission light of the light source that emits pulse light. The distance calculation unit calculates a distance to the object based on image data captured by the ToF sensor. The estimation unit estimates the modulation frequency of the light source generated from the light source clock based on pieces of image data captured in an operation mode switched by the mode switching unit.

Abstract: Some embodiments of the present disclosure relate to a roofing system. In some embodiments, the roofing system includes a first roofing material, wherein the first roofing material comprises a top surface and a bottom surface. In some embodiments, the top surface of the first roofing material comprises a nail zone with a plurality of fines. In some embodiments, the roofing system includes a second roofing material, wherein the second roofing material comprises a top surface and a bottom surface. In some embodiments, the bottom surface of the second roofing material comprises a plurality of fines. In some embodiments, the roofing system comprises and a patterned adhesive, which directly contacts at least a portion of the plurality of fines in the nail zone and at least a portion of the plurality of fines on the bottom surface of the second roofing material.

Abstract: Methods of increasing sIgA and mucin 5B levels in an individual's oral cavity are disclosed. The methods comprise applying to the individual's oral cavity in an amount effective to increase sIgA and mucin 5B levels in the individual's oral cavity, an oral care composition comprising: zinc phosphate, stannous fluoride and optionally, an organic acid buffer system.