Abstract: The present invention relates to a pharmaceutical composition containing, as an active ingredient, niclosamide or pharmaceutically acceptable salts thereof, for treating or preventing disease related to Axin-GSK3 interaction, such as familial adenomatosis polyposis (FAP). According to the present invention, familial adenomatosis polyposis (FAP) which causes pain due to lack of specific treatment methods, can be effectively treated using niclosamide, which is a safe drug approved by the FDA.

Abstract: Disclosed are a chloroethylene-based nanocomposite composition comprising a chloroethylene-based resin; a nanoclay comprising a coupling agent bonded thereto; and at least one polymer selected from unsaturated organic acid-based resins or polycarboxylic acid-based resins, and a method of preparing the same.

Abstract: The present invention relates to a vinyl chloride-based polymer containing an unsaturated fatty acid ester at a specific ratio, a method for preparing the same, a thermoplastic resin composition containing the same, and a thermoplastic resin molded article produced from the composition. The vinyl chloride-based polymer may have good processability, and thus, the thermoplastic resin molded article produced from the thermoplastic resin composition containing the vinyl chloride-based polymer may have high impact strength and improved appearance characteristics.

Abstract: A touch controller includes a touch data generator that is connected to a plurality of sensing lines, the touch data generator sensing a change in capacitance of a sensing unit connected to each of the sensing lines and generating touch data by processing the sensing signal corresponding to the result of sensing; and a signal processor that controls a timing of generating the touch data by receiving at least one piece of timing information for driving a display panel from a timing controller, and then providing either the timing information or a signal generated from the timing information as a control signal to the touch data generator.

Abstract: The present invention relates to a method of preparing a vinyl chloride-based copolymer having excellent plasticity and processability, a vinyl chloride-based copolymer prepared thereby, a thermoplastic resin composition including the vinyl chloride-based copolymer, and a thermoplastic resin molded article prepared from the composition. Since the preparation method may improve copolymerizability with a vinyl chloride-based monomer by continuously adding or dividedly adding an unsaturated fatty acid ester mixture used as a comonomer during the time of specific polymerization conversion rate, the unreacted unsaturated fatty acid ester mixture may be reduced, and, as a result, the conversion rate of the vinyl chloride-based copolymer may be significantly improved. Thus, plasticity and processability of a vinyl chloride-based copolymer prepared by the above method may be significantly improved.

Abstract: Provided are a cutting insert and a tool holder on which the cutting insert is provided. The cutting insert includes a circular upper surface, a circular lower surface, a cylindrical lateral surface for connecting the upper surface and the lower surface, an upper cutting edge formed between the upper surface and the lateral surface, a lower cutting edge formed between the lower surface and the lateral surface, and a plurality of rotation-preventing parts provided at the lateral surface so as to prevent the cutting insert from rotating with respect to the tool holder. Each rotation preventing part includes an inner curved surface recessed toward the center of the lateral surface and convexly rounded so as to form concentric circles in conjunction with the lateral surface, and a stepped rotation-preventing surface parallel to the axial direction of the insert and connecting the inner curved surface and the lateral surface.

Abstract: The purpose of the present invention is to provide a cutting insert capable of reducing cutting load and enhancing squareness.

Abstract: A touch controller includes a touch data generator that is connected to a plurality of sensing lines, the touch data generator sensing a change in capacitance of a sensing unit connected to each of the sensing lines and generating touch data by processing the sensing signal corresponding to the result of sensing; and a signal processor that controls a timing of generating the touch data by receiving at least one piece of timing information for driving a display panel from a timing controller, and then providing either the timing information or a signal generated from the timing information as a control signal to the touch data generator.

Abstract: A cutting insert for an indexable drill according to the present disclosure may be used for external cutting or internal cutting depending on a position and a direction in which the cutting insert is installed even though a single type of cutting insert is provided. In addition, the cutting insert for an indexable drill according to the present disclosure has a section of the internal cutting edge which is involved in a cutting process or a section of the internal cutting edge which is not involved in the cutting process, which are clearly distinguished from each other, and as a result, the cutting insert may be rotated and mounted, and reversed and mounted on a drill body, such that maximum eight corners may be used to perform a cutting process.

Abstract: The present invention relates to a method of preparing a vinyl chloride-based polymer, which includes inducing the nucleation of particles by adding a mercaptan-based chain transfer agent to a monomer composition including a vinyl chloride-based monomer and a preliminary polymerization initiator (preliminary polymerization); and preparing a polymer by mixing a vinyl chloride-based monomer and the particle nuclei and adding a main polymerization initiator (main polymerization). In the preparation method, a vinyl chloride-based polymer having a uniform molecular weight distribution and a desired number average molecular weight may be provided by controlling a degree of polymerization of a vinyl chloride-based polymer prepared in such a way that dispersibility is ensured by adjusting the point of time to add the mercaptan-based chain transfer agent to the point of time to reach a specific conversion rate of the preliminary polymerization.

Abstract: The present invention relates to a method of preparing a vinyl chloride-based polymer, which may prepare a vinyl chloride-based polymer with excellent surface properties by adjusting a foam level generated during a polymerization reaction to an appropriate value, a vinyl chloride-based polymer prepared thereby, and an apparatus for preparing a vinyl chloride-based polymer which may prepare the vinyl chloride-based polymer. The method of preparing a vinyl chloride-based polymer according to the present invention may prepare a vinyl chloride-based polymer with excellent surface properties, for example, fewer occurrences of fish-eyes and excellent transparency, by performing a polymerization reaction while maintaining the level of a foam generated during the polymerization reaction at an appropriate value.

Abstract: The present invention relates to a method for preparing a vinyl chloride-based polymer, to a vinyl chloride-based polymer, and to a vinyl chloride-based polymer composition comprising same, the method comprising: a first step of bulk polymerizing a vinyl chloride-based monomer under the presence of an initiator; and a second step of obtaining a vinyl chloride-based polymer after completing the bulk polymerization, wherein a phosphite is input in the first step.

Abstract: Provided are a vinyl chloride-based copolymer, as a secondary particle in which primary particles are assembled, which may exhibit excellent mechanical properties and transparency as well as excellent plasticity by having an average pore diameter of 100 nm or less and a porosity of 40 vol % or less, including 65 wt % to 97 wt % of a vinyl chloride-based monomer-derived repeating unit; and 3 wt % to 35 wt % of cis and trans isomers of an unsaturated fatty acid ester-derived repeating units, and including the repeating units respectively derived from the cis and trans isomers of the unsaturated fatty acid ester in a weight ratio of 60:40 to 99:1, and a method of preparing the same.

Abstract: The technical objective of the present invention is to provide a double-sided cutting insert having a high feed rate, which can increase the edge strength and reduce the cutting load, and thus can be suitable for high feed rate processing.

Abstract: A technical object of the present disclosure is to provide an insert, which can maintain rigidity thereof regardless of a clearance angle of a clearance surface that forms a circular cutting edge. To this end, the insert according to the present disclosure includes a circular upper surface, a circular lower surface, and a clearance surface portion connecting the upper surface and the lower surface. The clearance surface portion is divided into first and second clearance surfaces along a circumference thereof, by a first wave line that forms a waveform of valleys facing the lower surface and mounts facing the upper surface.

Abstract: A technical object is to provide an insert capable of preventing escaping of the insert from an assembly of the insert and a tool holder. To this purpose, the insert includes an insert body, and a holder fastening portion provided in the insert body to be fastened to the tool holder, in which the holder fastening portion includes one or more fastening holes formed through the insert body from an upper surface to a lower surface, and one or more locking recesses formed by being recessed in a lower surface periphery of the insert body.

Abstract: The present disclosure relates to a cutting insert and an indexable drill. The cutting insert and the indexable drill according to the present disclosure are configured such that when the cutting insert is mounted on the indexable drill, the cutting insert is easily inserted into the indexable drill at the initial time, and strong coupling force is implemented between the indexable drill and the cutting insert at a point of time at which the cutting insert is completely mounted. In addition, the cutting insert, according to the present disclosure, has excellent rigidity, when compared to cutting inserts in the related art that perform identical/similar cutting processing, since a portion, which is weak in rigidity, is provided as a thick portion.

Abstract: A semiconductor memory apparatus, including a first mat which includes a first bit line and a first word line and a second mat which includes a second bit line and a second word line, includes a first bit line driving circuit configured to enable the first bit line in response to a first bit line select signal and a first machine bit line select signal; a second bit line driving circuit configured to enable the second bit line in response to a second bit line select signal and a second machine bit line select signal; a column-related decoding circuit configured to selectively enable the first and second bit line select signals in response to a column address; and a state machine configured to selectively enable the first and second machine bit line select signals in response to the column address.

Abstract: The present invention relates to a hard coating including an MT-TiCN layer and an ?-alumina layer which are formed by using a chemical vapor deposition method. A hard coating for cutting tools, which is a coating formed on a base material of a cutting tool formed of a hard material, the coating comprising: a TiCN layer; and an ?-alumina layer formed on the TiCN layer, wherein: the ?-alumina layer has a main peak (maximal strength peak) of (006) plane located between 20-40 degrees during a psi rocking analysis by an XRD; a residual stress in the ?-Al2O3 layer is ?0.9-0.4 GPa; the TiCN layer is composed of TiCxNyOz (x+y+z?1, x>0, y>0, z?0); a composition ratio of C/(C+N) is greater than or equal to 0.4 and smaller than 0.5; the ratio of TC(220)/TC(422) is smaller than 0.45; and the ratio of TC(220)/TC(422) is less than 0.45.

Abstract: A hard coating includes a thin film layer which has a total thickness of 0.5-10 ?m and has an overall composition of Al1-a-bTiaMebN (0.2<a?0.6, 0<b?0.15) , where Me is a nitride constituent element having a thermal expansion coefficient of greater than 2.7×10?6/° C. and less than 9.35×10?6/° C., wherein the thin film layer has a structure in which a nano-multilayered-structure of thin layers A, B and C, thin layer B being disposed between thin layer A and thin layer C, is repeatedly laminated at least once.