Abstract: Various embodiments for managing data by a processor in a multi-tiered computing storage environment. Based on Input/Output (I/O) statistics, a ranking mechanism is applied to differentiate data between at least a cache rank and a Solid State Drive (SSD) rank. The ranking mechanism migrates data between the cache rank and SSD rank such that storage space in the cache rank is reserved for those of the plurality of data workload types having a greater adverse effect on a storage performance characteristic if stored in the SSD rank than if those workload types were stored in the cache rank.

Abstract: Provided herein are a stable solution formulation of an ETAR antibody, and use thereof in treating, preventing, or alleviating one or more symptoms of pulmonary arterial hypertension or one or more symptoms of cancer of a reproductive organ.

Abstract: Monitoring the division of input/output (I/O) loading within a storage system is provided where the storage system includes one or more storage devices and one or more ranks, each rank including a plurality of extents. The I/O loading of individual extents is estimated for each of the one or more ranks of the storage system by determining an average disk utilization in a rank, measuring a total heat for all extents in the rank, and based on the determined average disk utilization in the rank and the measured total heat for all extents in the rank, calculating a contribution of each extent to the utilization of the rank.

Abstract: Various embodiments for managing data by a processor in a multi-tiered computing storage environment. Based on Input/Output (I/O) statistics, a ranking mechanism is applied to differentiate data between at least a cache rank and a Solid State Drive (SSD) rank. The ranking mechanism migrates data between the cache rank and SSD rank such that storage space in the cache rank is reserved for those of the plurality of data workload types having a greater adverse effect on a storage performance characteristic if stored in the SSD rank than if those workload types were stored in the cache rank.

Abstract: The present invention belongs to the technical field of embryo cryopreservation. In particular, the present invention relates to an in-vitro embryonic culture medium for improving the thawed recovery rate of an embryo, comprising an inhibitor of Cathepsin L inhibitor, for example, E-64d. The present invention also relates to a method for improving the freezing resistance and the thawing recovery rate of an embryo and a method for freezing an embryo. With the present invention, the freezing resistance and the thawing recovery rate of an embryo are significantly improved.

Abstract: Various embodiments for managing data by a processor in a multi-tiered computing storage environment. Input/Output (I/O) statistics are examined from each of cache and device drivers in the computing storage environment. Based on the I/O statistics, a ranking mechanism is applied to differentiate data between at least a cache rank and a Solid State Drive (SSD) rank. The ranking mechanism migrates data between the cache rank and SSD rank such that storage space in the cache rank is reserved for those of the plurality of data workload types having a greater adverse effect on a storage performance characteristic if stored in the SSD rank than if those workload types were stored in the cache rank.

Abstract: Provided are transmitting, receiving and communication systems of an optical network and a method for modulating a signal. The transmitting system includes: first Passive Optical Network (PON) equipment, configured to output a binary digital signal; and an M-order digital modulator, configured to modulate the binary digital signal into an M-order digital signal, and output the M-order digital signal, wherein each transmission symbol in the M-order digital signal carries information of N=log2M bits, where N is a natural number greater than 1 and M is a natural number. By the disclosure, the problems in the related art is solved, the bandwidths required by transmission are further reduced, and the actual cost of the optical transceiver modules is lowered.

Abstract: Disclosed is a stable pharmaceutical solution formulation of a GLP-1R antibody fusion protein, comprising a therapeutically effective amount of the GLP-1R antibody fusion protein, an amino acid, a surfactant and a buffer system. The final concentration of the amino acid is 1-500 mM, the final concentration of the surfactant is 0.01%-0.5%, and the pH value of the stable solution formulation is from 5.0 to 8.0. The stable solution formulation of the present invention can be used in the treatment of diabetes, obesity and conditions associated therewith.

Abstract: An optical-electrical receiving and transmitting method and apparatus, as well as an optical-electrical transceiving method and device and an optical-electrical transceiver are provided. The optical-electrical transceiving processing method may include: in a reception direction, a received optical signal is split into multipath optical signals, the multipath optical signals are processed into multipath parallel electrical signals, and the multipath parallel electrical signals are converted into a single-path serial electrical signal; in a transmission direction, a received single-path serial electrical signal, which is to be transmitted, is converted into multipath parallel electrical signals, then the multipath parallel electrical signals are processed into multipath optical signals, and finally the multipath optical signals are combined into a single beam of optical signals.

Abstract: A method, for migrating newly allocated data into a second storage tier, includes receiving a request to store a data item. The method includes allocating an extent to a first storage tier to store the new data item. The method includes determining whether an extent is newly allocated on the first storage tier. The method includes migrating, by avoiding a learning phase, the newly allocated extent to the second storage tier from the first storage tier.

Abstract: Aspects of the present disclosure are directed toward a system for managing the migration of extents on tiered systems. The system can include receiving a space reservation request for one or more requested extents on a first storage tier of a storage system. The system can also include releasing a first storage tier reserve space that includes one or more first tier reserved extents in response to the first storage tier reserve space being insufficient for the reservation request. The system can also include migrating the one or more requested extents to the first storage tier reserve space.

Abstract: Aspects of the present disclosure are directed toward a computer program product for managing the migration of extents on tiered systems. The computer program product can be configured to receive a space reservation request for one or more requested extents on a first storage tier of a storage system. The computer program product can also be configured to release a first storage tier reserve space that includes one or more first tier reserved extents in response to the first storage tier reserve space being insufficient for the reservation request. The computer program product can also be configured to migrate the one or more requested extents to the first storage tier reserve space.

Abstract: Various technologies described herein pertain to evaluating a state of a computer-executable application. User interface control information for opened graphical user interface windows of the computer-executable application can be captured during execution of the computer-executable application and used to generate a user interface fingerprint identifier. Additionally, an event log of the computer-executable application can be captured during the execution of the computer-executable application and used to generate an event fingerprint identifier. A global fingerprint identifier that maps to the state of the computer-executable application can be determined based on the user interface fingerprint identifier and the event fingerprint identifier. A query (including the global fingerprint identifier) for execution by a capture store computing system can be generated.

Abstract: Provided are a computer program product, system, and method for modeling workload information for a primary storage and a secondary storage. A determination is made of: a first type and second type of Input/Output (I/O) operations with respect to extents configured in the primary storage; a cumulative I/O workload for the primary storage based on a first type and a second type of I/O operations at different cumulative storage amounts of the primary storage indicating a concentration of the I/O workload on the primary storage; and cumulative I/O workload for the secondary storage based on the first type and the second type of I/O operations at different storage amounts indicating a concentration of the I/O workload of the first type of I/O operations on the secondary storage. A performance gap is determined based on the cumulative I/O workloads for the primary and secondary storages at one of the storage amounts.

Abstract: An optical module and an optical device applicable to the optical module, wherein the optical module includes a laser emission unit, a laser reception unit, a video detector and an optical assembly, the optical assembly including: a band-pass device F1 with a small-angle incidence filter sheet, wherein among optical signals transmitted to F1 via a common port of F1, the optical signal in a first optical wavelength band is passed by the small-angle incidence filter sheet and output to the video detector via the passing port thereof; and the optical signals in other bands are reflected by the small-angle incidence filter sheet and output via the reflection port thereof; a filter sheet F2 configured to pass the optical signal emitted by the laser emission unit to the reflection port of F1 and to reflect the optical signal, received by the laser reception unit, output via the reflection port of F1.

Abstract: A method, for migrating newly allocated data into a second storage tier, includes receiving a request to store a data item. The method includes allocating an extent to a first storage tier to store the new data item. The method includes determining whether an extent is newly allocated on the first storage tier. The method includes migrating, by avoiding a learning phase, the newly allocated extent to the second storage tier from the first storage tier.

Abstract: Aspects of the present disclosure are directed toward a computer program product for managing the migration of extents on tiered systems. The computer program product can be configured to receive a space reservation request for one or more requested extents on a first storage tier of a storage system. The computer program product can also be configured to release a first storage tier reserve space that includes one or more first tier reserved extents in response to the first storage tier reserve space being insufficient for the reservation request. The computer program product can also be configured to migrate the one or more requested extents to the first storage tier reserve space.

Abstract: Aspects of the present disclosure are directed toward a system for managing the migration of extents on tiered systems. The system can include receiving a space reservation request for one or more requested extents on a first storage tier of a storage system. The system can also include releasing a first storage tier reserve space that includes one or more first tier reserved extents in response to the first storage tier reserve space being insufficient for the reservation request. The system can also include migrating the one or more requested extents to the first storage tier reserve space.