Patents by Inventor Yong Liang

Yong Liang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MAGNETIC APPARATUS HAVING ELECTRICALLY INSULATING LAYER
    Publication number: 20180191228
    Abstract: In one embodiment an apparatus can include a plurality of magnetic material layers. In one embodiment, an apparatus can include one or more electrically insulating layer, wherein the plurality of magnetic material layers and the one or more electrically insulating layer define a stacked up structure, wherein an electrically insulating layer of the one or more electrically insulating layer includes thermally conductive dielectric material.
    Type: Application
    Filed: December 29, 2016
    Publication date: July 5, 2018
    Applicant: General Electric
    Inventors: Yong LIANG, James BRAY, Francis JOHNSON, John KRAHN, Vance ROBINSON, Manoj SHAH
  • CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS
    Publication number: 20180134669
    Abstract: Chemical entities based on quinoxaline that are kinase inhibitors are described. Specifically quinoxaline derivatives of Formula I, containing a diarylamide or diarylurea substructure that inhibit Braf mutant kinase activity, pharmaceutical compositions containing the inhibitor compounds and methods of treatment of cancer comprising administering an effective amount of the Braf inhibitor compound are described.
    Type: Application
    Filed: October 16, 2017
    Publication date: May 17, 2018
    Inventors: Xiangping QIAN, Yong-Liang ZHU
  • SUBSTITUTED QUINAZOLINES FOR INHIBITING KINASE ACTIVITY
    Publication number: 20180125855
    Abstract: Chemical entities that are kinase inhibitors, pharmaceutical compositions and methods of treatment of cancer are described.
    Type: Application
    Filed: November 7, 2017
    Publication date: May 10, 2018
    Inventors: Xiangping Qian, Yong-Liang Zhu
  • SYSTEM AND METHOD OF ASSOCIATING METADATA WITH COMPUTING RESOURCES ACROSS MULTIPLE PROVIDERS
    Publication number: 20180123904
    Abstract: Systems, apparatuses, and methods for modifying metadata associated with database objects obtained from providers, such as cloud providers, are disclosed. Modifying metadata associated with database objects obtained from cloud providers may include identifying resources in a computer network that originate from providers, such as cloud providers that do not have associated metadata. A user interface that includes the resources may be generated, and the resource may receive input to select the resources and a descriptor that may be associated with the resources. The selected resources may then be associated, in a configuration management dataset, with metadata derived from the selected descriptor. The metadata may indicate an association of the selected resources to a parameter.
    Type: Application
    Filed: May 10, 2017
    Publication date: May 3, 2018
    Inventors: Utpal Thakrar, Yong Liang
  • COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR
    Publication number: 20180111929
    Abstract: Compounds active on protein kinases are described, as well as methods of using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases.
    Type: Application
    Filed: May 25, 2017
    Publication date: April 26, 2018
    Inventors: Prabha N. Ibrahim, Dean R. Artis, Ryan Bremer, Gaston Habets, Shumeye Mamo, Marika Nespi, Chao Zhang, Jiazhong Zhang, Yong-Liang Zhu, Rebecca Zuckerman, Brian West, Yoshisa Suzuki, James Tsai, Klaus-Peter Hirth, Gideon Bollag, Wayne Spevak, Hanna Cho, Samuel J. Gillette, Guoxian Wu, Hongyao Zhu, Shenghua Shi
  • Insulation film and method for making insulation film
    Patent number: 9942989
    Abstract: The present invention provides an insulation film and a method for making the insulation film, comprising a film upper layer and a film lower layer, wherein both of the film upper layer and film lower layer are made of a heat conduction plastics material, the heat conduction plastics material contains a heat conduction additive; and a film intermediate layer located between the film upper layer and the film lower layer. The film intermediate layer is made of a heat conduction plastics material, and the heat conduction plastics material contains a conductive additive An upper surface of the film intermediate layer is bound together with a lower surface of the film upper layer, and a lower surface of the film intermediate layer is bound together with an upper surface of the film lower layer.
    Type: Grant
    Filed: June 23, 2014
    Date of Patent: April 10, 2018
    Assignee: ILLINOIS TOOL WORKS INC.
    Inventors: Hongchuan Liao, Chris Benson, Yong Liang, Tom Carlson
  • HIGH TEMPERATURE ANNEALING IN X-RAY SOURCE FABRICATION
    Publication number: 20180090293
    Abstract: The present disclosure relates to multi-layer X-ray sources having decreased hydrogen within the layer stack and/or tungsten carbide inter-layers between the primary layers of X-ray generating and thermally-conductive materials. The resulting multi-layer target structures allow increased X-ray production, which may facilitate faster scan times for inspection or examination procedures.
    Type: Application
    Filed: September 29, 2016
    Publication date: March 29, 2018
    Inventors: Yong Liang, Vance Scott Robinson
  • CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS
    Publication number: 20180072688
    Abstract: Chemical entities that are kinase inhibitors, pharmaceutical compositions and methods of treatment of cancer are described.
    Type: Application
    Filed: August 14, 2017
    Publication date: March 15, 2018
    Inventors: Xiangping Qian, Yong-Liang Zhu
  • MULTI-LAYER X-RAY SOURCE FABRICATION
    Publication number: 20180075998
    Abstract: Fabrication of a multi-layer X-ray source is disclosed using bulk structures to fabricate a multi-layer target structure. In one implementation, layers of X-ray generating material, such as tungsten, are interleaved with thermally conductive layers, such as diamond layers. To prevent delamination of the layers, various mechanical, chemical, and/or structural approaches may also be employed.
    Type: Application
    Filed: September 15, 2016
    Publication date: March 15, 2018
    Inventors: Thomas Robert Raber, Vance Scott Robinson, Yong Liang
  • CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS
    Publication number: 20180022714
    Abstract: Chemical entities that are kinase inhibitors, pharmaceutical compositions and methods of treatment of cancer are described.
    Type: Application
    Filed: June 8, 2017
    Publication date: January 25, 2018
    Inventors: Xiangping QIAN, Yong-liang ZHU
  • MULTILAYER X-RAY SOURCE TARGET
    Publication number: 20180005794
    Abstract: The present disclosure relates to the production and use of a multi-layer X-ray source target. In certain implementations, layers of X-ray generating material may be interleaved with thermally conductive layers. To prevent delamination of the layers, various mechanical, chemical, and structural approaches are related, including approaches for reducing the internal stress associated with the deposited layers and for increasing binding strength between layers.
    Type: Application
    Filed: June 30, 2016
    Publication date: January 4, 2018
    Inventors: Yong Liang, Vance Scott Robinson, Thomas Robert Raber, George Theodore Dalakos
  • MULTI-LAYER X-RAY SOURCE TARGET
    Publication number: 20180005795
    Abstract: The present disclosure relates to the production and use of a multi-layer X-ray source target. In certain implementations, layers of X-ray generating material may be interleaved with thermally conductive layers. To prevent delamination of the layers, various mechanical, chemical, and structural approaches are related, including approaches for reducing the internal stress associated with the deposited layers and for increasing binding strength between layers.
    Type: Application
    Filed: April 13, 2017
    Publication date: January 4, 2018
    Inventors: Vance Scott Robinson, Yong Liang, Thomas Robert Raber, George Theodore Dalakos, Christoph Wild
  • Substituted quinazolines for inhibiting kinase activity
    Patent number: 9849139
    Abstract: Chemical entities that are kinase inhibitors, pharmaceutical compositions and methods of treatment of cancer are described.
    Type: Grant
    Filed: November 22, 2016
    Date of Patent: December 26, 2017
    Assignee: NeuPharma, Inc.
    Inventors: Xiangping Qian, Yong-Liang Zhu
  • Compounds and methods for kinase modulation, and indications therefor
    Patent number: 9844539
    Abstract: Compounds active on protein kinases are described, as well as methods of using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases.
    Type: Grant
    Filed: September 8, 2016
    Date of Patent: December 19, 2017
    Assignee: Plexxikon Inc.
    Inventors: Guoxian Wu, Jiazhong Zhang, Yong-Liang Zhu, Chao Zhang, Prabha N. Ibrahim, Songyuan Shi, Wayne Spevak, Dean R. Artis, James Tsai
  • BENZENESULFONAMIDE DERIVATIVES OF QUINOXALINE, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR USE IN METHODS FOR TREATING CANCER
    Publication number: 20170340630
    Abstract: Chemical entities that are kinase inhibitors, pharmaceutical compositions and methods of using these chemical entities, e.g., for treatment of cancer are described.
    Type: Application
    Filed: January 6, 2017
    Publication date: November 30, 2017
    Inventors: Yong-Liang Zhu, Xiangping Qian
  • CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS
    Publication number: 20170334859
    Abstract: Chemical entities that are kinase inhibitors, pharmaceutical compositions and methods of treatment of cancer are described.
    Type: Application
    Filed: May 18, 2017
    Publication date: November 23, 2017
    Inventors: Xiangping Qian, Yong-Liang Zhu
  • Certain chemical entities, compositions, and methods
    Patent number: 9822081
    Abstract: Chemical entities based on quinoxaline that are kinase inhibitors are described. Specifically quinoxaline derivatives of Formula I, containing a diarylamide or diarylurea substructure that inhibit Braf mutant kinase activity, pharmaceutical compositions containing the inhibitor compounds and methods of treatment of cancer comprising administering an effective amount of the Braf inhibitor compound are described.
    Type: Grant
    Filed: November 4, 2016
    Date of Patent: November 21, 2017
    Assignee: NEUPHARMA, INC.
    Inventors: Xiangping Qian, Yong-Liang Zhu
  • METHOD AND SYSTEM FOR DETERMINING AN ESTIMATED SURVIVAL TIME OF A SUBJECT WITH A MEDICAL CONDITION
    Publication number: 20170329925
    Abstract: A system and a method for determining an estimated survival time of a subject with a medical condition utilizes the novel RS-AFT model and is especially suitable and highly advantageous for survival analysis based on microarray gene expression data because of its exceptional performance of gene selection, stable noise resistance, and high prediction precision.
    Type: Application
    Filed: May 10, 2016
    Publication date: November 16, 2017
    Inventors: Yong Liang, Hua Chai, Zi-yi Yang, Xiao-Ying Liu
  • METHOD AND SYSTEM FOR DETERMINING AN ASSOCIATION OF BIOLOGICAL FEATURES WITH A MEDICAL CONDITION
    Publication number: 20170329912
    Abstract: A system and a method for determining an association of one or more biological features with a medical condition provides empirical results and simulations confirming that the involvement of both L1/2-regularized logistic regression and L2-regularized logistic regression in the regression model is highly competitive against usual approaches like Lasso, L1/2, SCAD-L2, and Elastic net in analyzing high dimensional and low sample sizes data.
    Type: Application
    Filed: May 10, 2016
    Publication date: November 16, 2017
    Inventors: Yong Liang, Hai-Hui Huang, Xiao-Ying Liu
  • METHOD AND SYSTEM FOR DETERMINING AN ASSOCIATION OF BIOLOGICAL FEATURE WITH MEDICAL CONDITION
    Publication number: 20170329913
    Abstract: A method and a system for determining an association of at least one biological feature with a medical condition utilizes the novel L1/2 penalized network-constraint regression model to achieve an improved biological analysis, in particular by solving high-dimensional problems. The method and the system of the present invention attain high accuracy and preciseness.
    Type: Application
    Filed: May 10, 2016
    Publication date: November 16, 2017
    Inventors: Yong Liang, Hai-Hui Huang, Xiao-Ying Liu