Patents by Inventor Yong Shi

Yong Shi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12274725
    Abstract: The present disclosure involves a composition and method of treatment of glioblastoma, using ZIKA virus.
    Type: Grant
    Filed: June 11, 2018
    Date of Patent: April 15, 2025
    Assignees: Washington University, The Cleveland Clinic Foundation, The Board of Regents of the University of Texas System
    Inventors: Michael Diamond, Milan Chheda, Jeremy Rich, Pei-Yong Shi, Zhe Zhu, Matthew Gorman
  • Patent number: 12269522
    Abstract: A method is disclosed. The method includes moving a vehicle having a plurality of wheels along a track, receiving a marker data or a marker signal from a marker at a location of the track using a reader of the vehicle, controlling a first rotational speed of a first wheel of the plurality of wheels at the location of the track based on the marker data or the marker signal, and controlling a second rotational speed of a second wheel of the plurality of wheels at the location of the track, independently of the first rotational speed, based on the marker data or the marker signal. The first rotational speed is different from the second rotational speed.
    Type: Grant
    Filed: March 18, 2024
    Date of Patent: April 8, 2025
    Assignee: SOUTS-NG, LLC
    Inventors: Frank F. Wu, Yong Shi
  • Publication number: 20250000963
    Abstract: The present invention discloses a live attenuated strain of Zika virus (ZIKV) having a deletion in the 3? untranslated region (3?UTR) of the viral genome, which may affect viral RNA synthesis and sensitivity to type I interferon inhibition, but may not affect viral RNA translation. The present invention also discloses the use of these live attenuated ZIKV strains in the preparation of ZIKV vaccines and for providing immunoprotection against ZIKV infection and congenital ZIKV syndrome, particularly in pregnant females.
    Type: Application
    Filed: June 16, 2023
    Publication date: January 2, 2025
    Inventors: Pei-Yong SHI, Xuping XIE, Chao SHAN
  • Patent number: 12098549
    Abstract: This technology comprises a combined accessory of an in-situ concrete 3-D printed horizontal load-bearing member and a preparation method. The combined accessory includes 3-D printed concrete and a bottom mesh, the 3-D printed concrete contains fine aggregates having the particle size of 0.08 mm-4.75 mm, and the fluidity of the 3-D printed concrete is larger than or equal to 110 mm and smaller than or equal to 190 mm; the bottom mesh is a reinforcing mesh or expanded metal, the diameter of the reinforcing bar is larger than or equal to 0.5 mm, and the mesh aperture of the reinforcing mesh is smaller than or equal to 7.5 times of an upper limit of the particle size of the fine aggregate and is larger than or equal to 7.5 times of a lower limit of the particle size of the fine aggregate.
    Type: Grant
    Filed: May 5, 2022
    Date of Patent: September 24, 2024
    Assignee: INNER MONGOLIA UNIVERSITY OF TECHNOLOGY
    Inventors: Yong Shi, Yongli Hou, Xiaoyan He, Yuanhong Hao
  • Patent number: 12077540
    Abstract: A series of substituted 4,6-dihydrospiro[[1,2,3]triazolo[4,5-b]pyridine-7,3?-indoline]-2?,5(3H)-dione analogues, the use thereof and the preparation thereof.
    Type: Grant
    Filed: July 1, 2022
    Date of Patent: September 3, 2024
    Assignee: The Board of Regents of The University of Texas System
    Inventors: Jia Zhou, Pei-Yong Shi, Jimin Xu, Xuping Xie
  • Publication number: 20240219099
    Abstract: The present disclosure relates to the technical field of refrigerators and manufacturing therefor, and in particular, to a refrigerator air duct structure, a refrigerator refrigerating air duct, a refrigerator freezing air duct, and a refrigerator. The refrigerator air duct structure comprises a groove integrally formed on a refrigerating container liner and a cover plate covering the groove; the groove is communicated with an air supply duct, and comprises a main groove and a plurality of branch grooves communicated with the main groove; the plurality of branch grooves are arranged at intervals on the refrigerator container liner; and the cover plate is provided with a through-hole for allowing cold air to flow into a refrigerator body of a refrigerator.
    Type: Application
    Filed: July 23, 2021
    Publication date: July 4, 2024
    Inventors: Yong SHI, Zhengguang LYU
  • Publication number: 20240186496
    Abstract: Zinc containing electrodes and anodes, processes for their production, and cells including said electrodes and anodes are disclosed. The electrodes and anodes can include zinc adjacent to a copper current collector and carrying lithium metal. Processes include the deposition of zinc and then lithium onto the current collector and the electrochemical products include the electrodes and anodes in a lithium-metal cell.
    Type: Application
    Filed: March 14, 2023
    Publication date: June 6, 2024
    Inventors: Jonathan T. Goodman, Yong Shi
  • Publication number: 20240116972
    Abstract: The present disclosure is concerned with 6-aza-nucleoside prodrugs that are capable of inhibiting a viral infection and methods of treating viral infections such as, for example, human immunodeficiency virus (HIV), human papillomavirus (HPV), chicken pox, infectious mononucleosis, mumps, measles, rubella, shingles, ebola, viral gastroenteritis, viral hepatitis, viral meningitis, human metapneumovirus, human parainfluenza virus type 1, parainfluenza virus type 2, parainfluenza virus type 3, respiratory syncytial virus, viral pneumonia, yellow fever virus, tick-borne encephalitis virus, Chikungunya virus (CHIKV), Venezuelan equine encephalitis (VEEV), Eastern equine encephalitis (EEEV), Western equine encephalitis (WEEV), dengue (DENV), influenza, West Nile virus (WNV), zika (ZIKV), Middle East Respiratory Syndromes (MERS), Severe Acute Respiratory Syndrome (SARS), and coronavirus disease 2019 (COVID-19), using these compounds.
    Type: Application
    Filed: November 15, 2023
    Publication date: April 11, 2024
    Inventors: Omar Moukha-Chafiq, Ashish Kumar Pathak, Shuklendu D. Karyakarte, Larry D. Bratton, Corinne E. Augelli-Szafran, Michael Diamond, Pei Yong Shi, Alec Jay Hirsch, Jessica Lee Smith, Daniel Streblow, Nicole Haese, Baoling Ying
  • Publication number: 20240110160
    Abstract: Certain embodiments are directed to a trans-complementation system, system components, and method of using the same for SARS-CoV-2 that can be performed at BSL-2 laboratories for COVID-19 research and countermeasure development. The system thus can be used by researchers in industry, academia, and government laboratories who lack access to BSL-3 facility. This approach also can be applied to other coronaviruses.
    Type: Application
    Filed: January 14, 2022
    Publication date: April 4, 2024
    Inventors: PEI-YONG SHI, XUPING XIE, XIANWEN ZHANG
  • Patent number: 11858956
    Abstract: The present disclosure is concerned with 6-aza-nucleoside prodrugs that are capable of inhibiting a viral infection and methods of treating viral infections such as, for example, human immunodeficiency virus (HIV), human papillomavirus (HPV), chicken pox, infectious mononucleosis, mumps, measles, rubella, shingles, ebola, viral gastroenteritis, viral hepatitis, viral meningitis, human metapneumovirus, human parainfluenza virus type 1, parainfluenza virus type 2, parainfluenza virus type 3, respiratory syncytial virus, viral pneumonia, yellow fever virus, tick-borne encephalitis virus, Chikungunya virus (CHIKV), Venezuelan equine encephalitis (VEEV), Eastern equine encephalitis (EEEV), Western equine encephalitis (WEEV), dengue (DENV), influenza, West Nile virus (WNV), zika (ZIKV), Middle East Respiratory Syndromes (MERS), Severe Acute Respiratory Syndrome (SARS), and coronavirus disease 2019 (COVID-19), using these compounds.
    Type: Grant
    Filed: December 17, 2021
    Date of Patent: January 2, 2024
    Assignees: Southern Research Institute, Oregon Health & Science University, Washington University in St. Louis, Board of Regents, The University of Texas System
    Inventors: Omar Moukha-Chafiq, Ashish Kumar Pathak, Shuklendu D. Karyakarte, Larry D. Bratton, Corinne E. Augelli-Szafran, Michael Diamond, Pei Yong Shi, Alec Jay Hirsch, Jessica Lee Smith, Daniel Streblow, Nicole Haese, Baoling Ying
  • Publication number: 20230416692
    Abstract: Certain embodiments of the invention include recombinant reverse genetic systems for SARS-COV-2 virus.
    Type: Application
    Filed: March 26, 2021
    Publication date: December 28, 2023
    Inventors: PEI-YONG SHI, VINEET MENACHARY, Xuping Xie
  • Publication number: 20230399384
    Abstract: Provided herein are antibodies binding to Coronavirus S protein and the uses of the antibodies in detecting and treating Coronavirus infection, such as COVID-19.
    Type: Application
    Filed: April 22, 2021
    Publication date: December 14, 2023
    Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Zhiqiang KU, Ningyan ZHANG, Zhiqiang AN, Xuping XIE, Pei-Yong SHI
  • Patent number: 11804625
    Abstract: A lithium-ion battery thermal management system and method based on PCM and mutually embedded fins. The thermal management system includes a battery box, a lithium-ion battery pack and a temperature detection unit are arranged in the battery box; the lithium-ion battery pack at least includes two cells, the periphery of each cell is wrapped by a battery inner shell and a battery outer shell, and PCM is filled between the battery inner shell and the battery outer shell; a plurality of fins are arranged on the battery outer shell on the opposite sides of the two adjacent cells, the fins are arranged at intervals, the fins on the opposite sides of the two adjacent cells are arranged in a staggered manner, and heat-conducting plates are connected between each fin and the battery inner shell.
    Type: Grant
    Filed: December 29, 2022
    Date of Patent: October 31, 2023
    Assignee: University of Nottingham Ningbo China
    Inventors: Yong Shi, Guanyi Chen, Hanyang Ye
  • Publication number: 20230303634
    Abstract: Certain embodiments of the invention include recombinant reverse genetic systems for Omicron variant of SARS-CoV-2 virus.
    Type: Application
    Filed: December 6, 2022
    Publication date: September 28, 2023
    Inventors: Hongjie Xia, Xuping Xie, Pei-Yong Shi
  • Patent number: 11730801
    Abstract: The present invention discloses a live attenuated strain of Zika virus (ZIKV) having a deletion in the 3? untranslated region (3?UTR) of the viral genome, which may affect viral RNA synthesis and sensitivity to type I interferon inhibition, but may not affect viral RNA translation. The present invention also discloses the use of these live attenuated ZIKV strains in the preparation of ZIKV vaccines and for providing immunoprotection against ZIKV infection and congenital ZIKV syndrome, particularly in pregnant females.
    Type: Grant
    Filed: February 14, 2018
    Date of Patent: August 22, 2023
    Assignee: Board of Regents, The University of Texas System
    Inventors: Pei-Yong Shi, Xuping Xie, Chao Shan
  • Publication number: 20230242440
    Abstract: The high-frequency vibration nicking device for microbead surfaces includes a high-frequency vibration assembly and a container. Microbeads or mixed materials of the microbeads and a grinding material are filled in the container, and the vibration output end of the high-frequency vibration assembly is connected with the container to perform high-frequency vibration on the microbeads. The high-frequency vibration nicking method for microbead surfaces includes steps of adding the microbeads into the container, turning on the high-frequency vibration assembly, and performing high-frequency vibration motion on the microbeads in the container under the action of the high-frequency vibration assembly.
    Type: Application
    Filed: January 17, 2023
    Publication date: August 3, 2023
    Inventor: Yong SHI
  • Publication number: 20230216102
    Abstract: A lithium-ion battery thermal management system and method based on PCM and mutually embedded fins. The thermal management system includes a battery box, a lithium-ion battery pack and a temperature detection unit are arranged in the battery box; the lithium-ion battery pack at least includes two cells, the periphery of each cell is wrapped by a battery inner shell and a battery outer shell, and PCM is filled between the battery inner shell and the battery outer shell; a plurality of fins are arranged on the battery outer shell on the opposite sides of the two adjacent cells, the fins are arranged at intervals, the fins on the opposite sides of the two adjacent cells are arranged in a staggered manner, and heat-conducting plates are connected between each fin and the battery inner shell.
    Type: Application
    Filed: December 29, 2022
    Publication date: July 6, 2023
    Inventors: Yong Shi, Guanyi Chen, Hanyang Ye
  • Patent number: 11662350
    Abstract: Provided is a method of detecting the presence of an anti-Zika virus (ZIKV) antibody in a sample, including contacting a sample with a suspension having a plurality of microspheres wherein individual microspheres are conjugated to a peptide and the peptide includes a ZIKV peptide selected from the group including ZIKV NS1, ZIKV NS5, and ZIKV envelope protein, forming a first incubated suspension by incubating said sample with said suspension to permit binding of anti-ZIKV antibodies present in the sample to said microspheres, forming a second incubated suspension by contacting said first incubated suspension with an anti-ZIKV antibody detecting-reagent to permit binding of the anti-ZIKV antibody detecting reagent to said microspheres, removing from the second incubated suspension anti-ZIKV antibody detecting-reagent molecules that are not bound to said microspheres, and detecting the presence of anti-ZIKV antibody detecting-reagent molecules in the second incubated suspension.
    Type: Grant
    Filed: November 29, 2021
    Date of Patent: May 30, 2023
    Assignee: HEALTH RESEARCH, INC.
    Inventors: Susan J. Wong, Pei-Yong Shi
  • Publication number: 20230148269
    Abstract: Provided herein is a system for measuring and analyzing skin and hair, which includes a skin and hair measurement and analysis device, a smart terminal of a user in which an application interlinked with the skin and hair measurement and analysis device is installed, and a server interlinked with the skin and hair measurement and analysis device and interlinked with the smart terminal.
    Type: Application
    Filed: December 11, 2020
    Publication date: May 11, 2023
    Inventor: Yong Shi KIM
  • Patent number: D1034261
    Type: Grant
    Filed: March 17, 2022
    Date of Patent: July 9, 2024
    Assignee: KC TECHNOLOGY CO., LTD.
    Inventor: Yong Shi Kim