Abstract: There are disclosed compounds that modulate the activity of inhibitors of apoptosis (IAPs), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.

Abstract: An intelligent fabric includes: a base layer with vent holes, a thermal insulation layer on the base layer and capable of being moved relative to the base layer, an instruction generator configured to generate a switch instruction, and a controller connected to the instruction generator and the thermal insulation layer, and configured to control the thermal insulation layer to be moved relative to the base layer in accordance with the switch instruction, so as to switch the thermal insulation layer between a state where the thermal insulation layer covers the vent holes completely and a state where the thermal insulation layer does not cover the vent holes, or among the state where the thermal insulation layer covers the vent holes completely, a state where the thermal insulation layer partially covers the vent holes, and the state where the thermal insulation layer does not cover the vent holes.

Abstract: Embodiments of the present application provide a method and a device for acquiring ECG data, and an ECG detection system. A method for acquiring ECG data, comprising: acquiring ECG signals of heart; performing a first-stage amplification on the ECG signals, a multiple of the first-stage amplification including 5 to 10 times; performing band-pass filtering process within a first frequency range on the ECG signals on which the first-stage amplification has been performed, the first frequency range being 0.1 Hz to 50 Hz; performing a second-stage amplification on the ECG signals on which the band-pass filtering process has been performed, a multiple of the second-stage amplification including 40 to 50 times; performing analog-to-digital conversion on the ECG signals on which the second-stage amplification has been performed, to generate ECG digital signals; and outputting the ECG digital signals.

Abstract: A database driven input system and a method for operating the same are provided. The database driven input system, for example, may include, but is not limited to, a memory configured to store a database comprising airport information, a touchscreen display, and a processor communicatively coupled to the touchscreen display and the database system, the processor configured to generate a database driven taxiway input interface comprising a database driven keyboard input interface, the database driven keyboard input interface comprising a smart keyboard configured to prevent invalid input based upon the airport information in the database, display the database driven taxiway input interface on the touchscreen display, receive an input from the touchscreen display, and dynamically update the database driven keyboard input interface based upon the input to the touchscreen display.

Abstract: Graphene is used as an interfacial layer to grow Si and other semiconductors or crystalline materials including two-dimensional Si and other structures on any foreign substrate that can withstand the growth temperature without the limitation matching condition typically required for epitaxial growth.

Abstract: Reviewing software source code by receiving a changeset containing identified source code text changes. A computer creates a workflow of a source code module using execution paths among logical groupings of source code statements. The computer identifies logical groupings of source code statements in the workflow that contain text changes. The computer generates an integrated graphical user interface that will display a visual indication of the text changes and the logical groupings that contain the text changes, visually indicate logical groupings that contain text changes when selected by a user, visually indicate source code statements associated with a selected logical grouping in the workflow, link user comments for a source code statement and logical groupings to the associated logical groupings and source code statements, respectively, and visually indicate the linked logical groupings and linked source code statements when a source code statement is selected.

Abstract: Benzodiazepine dimers having a structure represented by wherein R1 is wherein the variables in formulae (I), (Ia), and (Ib) are as defined in the application. Such dimers are useful as anti-cancer agents, especially when used in an antibody-drug conjugate (ADC).

Abstract: Co-selected images are labeled based on a topic score that is a measure of relevance of the co-selected image to a first topic to which a reference image belongs. The first topic to which the reference image belongs is identified based on a reference label associated with the reference image. The co-selected images are images that are selected for presentation subsequent to selection of the reference image during a user session. The co-selected images are identified based on selection data for user sessions in which the reference image was selected for presentation. The topic score is generated based on a frequency of selection of the co-selected image. Image search results for a second topic can be filtered to remove images that are labeled as belonging to the first topic or the image search results can be reordered to adjust the presentation positions at which images are referenced based on the topic to which the images belong.

Abstract: A circuit for control of time for read operation is disclosed which additionally incorporates a dummy device circuit and a dummy sensitive amplifier circuit, uses a current mirror circuit to mirror a reference current in a reference device circuit into the dummy device circuit to generate a mirrored current, and generates time control signals based on the mirrored current. Due to the same adaptation of the mirrored current to the size of a test device as the reference current, the time control signals are also adapted to the size of the test device. This addresses the problem of fixed time control signals arising from the use of a conventional RC relay circuit and enables the time control signals to change with the size of the test device as well as Process Voltage Temperature, thereby resulting in an effective reduction in average energy consumed in read operation.

Abstract: A circuit for erasing data includes: a high voltage generation unit, adapted for generating an erasing signal; a first control unit, adapted for modifying the erasing signal to a first conduction control signal with a decreased voltage ascending speed; a second control unit, adapted for sending a second conduction control signal based on the first conduction control signal; a lift unit, adapted for lifting an output voltage for erasing data based on the first conduction control signal; a switch unit, adapted for forming an electrical access between the high voltage generation unit and the output end of the circuit for erasing data; and a reference current generation unit, adapted for providing a bias current to the first control unit and the second control unit. Under a circumstance that erasing effect of storage units is improved, area of a chip is relatively reduced by using the circuit for erasing data.

Abstract: The present invention provides a shift register and a driving method thereof, a gate driving device and a display panel, such that the shift register can pull down the output terminal by means of DC voltage signals, which reduces the duty cycle of the clock signal and thereby lowers the power consumption of Thin Film Transistors. The shift register comprises a plurality of cascaded shift register elements, each of which comprises: an input module in response to the input signal outputted by an input signal terminal, an output module in response to a voltage signal outputted a the pull-up node, a reset module in response to the reset signal outputted by a reset signal terminal, a first pull-down module in response to the input signal and the reset signal, and a second pull-down module in response to a voltage signal of a pull-down node.

Abstract: Benzodiazepine dimers having a structure represented by wherein X comprises a heteroaromatic moiety and is as further defined in the application; R1 is and the other variables in formulae (I), (Ia), and (Ib) are as defined in the application. Such dimers are useful as anti-cancer agents, especially when used in an antibody-drug conjugate (ADC).

Abstract: The present disclosure provides a display panel and a display device, and the display panel includes an array substrate, a color filter substrate and at least a spacer disposed between the array substrate and the color filter substrate, where the array substrate or the color filter substrate is provided with plural touch electrodes disposed in a same layer and separated from each other, plural lines arranged in different layers from the touch electrodes, and an insulation layer disposed between the touch electrodes and the lines. The insulation layer is provided with via holes, for the connection of the corresponding touch electrodes and the lines, and the via hole is located within a region of the insulation layer on which an orthographic projection of the spacer is projected.

Abstract: Embodiments disclose a remote radio unit hub (RHUB), an indoor communications system, and a signal transmission method. The RHUB includes an input port module, a first output port module, and a processing module. The input port module is configured to connect to a baseband unit (BBU) in a wired manner and receive a first communications signal sent by the BBU. The first output port module is configured to connect to another RHUB in a wired manner. Additionally, the processing module is configured to send, according to the first communications signal received by the input port module, a second communications signal to the another RHUB by using the first output port module.

Abstract: An air filtration equipment, the air filtration equipment is installed in an ventilation area at an interface between indoor and outdoor spaces of a fixed space, the equipment comprising: a sensor configured to sense information on inhalable particles in outside air; at least one filtering layer configured to filter out inhalable particles in air entering from the ventilation area into the indoor space; and a control device connected with the sensor and the at least one filtering layer and configured to control the at least one filtering layer to expand according to the information sensed by the sensor, such that the expanded at least one filtering layer covers the ventilation area. Also, a screen window and a window are provided.

Abstract: This invention is a vinylcarbosiloxane resin that is the hydrosilation reaction product of 1,3,5,7 -tetravinyl-1,3,5,7-tetramethylcyclotetrasiloxane and a hydride-terminated linear polysiloxane, siloxane, or silane, having two terminal Si—H hydrogens reactive with vinyl groups in a hydrosilation reaction, in the presence of a platinum catalyst. Suitable hydride-terminated linear polysiloxanes, siloxances, and silanes include those having the structures: In another embodiment, the vinylcarbosiloxane resin can be reacted with one or more other hydrido-silanes and hydrido-polysiloxanes in the presence of a platinum catalyst to form a curable composition.

Abstract: The present invention is directed to devices formed from three-dimensional (3D) structures composed of metallic, ceramic or polymeric wires or bundles and yarns of wires that are either solid or hollow like a tube. The devices of the present invention offer the potential for 3D structures with multiple properties optimized concurrently, in some cases using a topology optimization routine that includes the 3D manufacturing constraints. The properties can be optimized in different directions. The 3D structures of the present invention include multiple properties that are optimized for a range of different applications, including heat transfer. The present invention also includes the methods for optimization of the 3D structures as well as methods of use of the 3D structures in heat transfer applications.

Abstract: A nucleic acid extraction method includes the following steps. Firstly, a mixture of a sample and a lysis buffer is provided. The pH of the lysis buffer is lower than 7. Then, the mixture of the sample and the lysis buffer is transferred to a nucleic acid catching chamber containing chitosan coating material, so that nucleic acid of the sample is bound to the chitosan coating material. Then, the chitosan coating material is washed with at least one wash buffer, thereby removing residual protein and cell debris. Then, the chitosan coating material is eluted with an elution buffer while heating the chitosan coating material, so that the nucleic acid is separated from the chitosan coating material. The pH of the elution buffer is higher than 7.

Abstract: An array substrate and a manufacturing method thereof and a display are disclosed. The array substrate includes a base substrate, a plurality of sub-pixels disposed on the base substrate, and a phase shift pattern disposed on the base substrate to separate the sub-pixels; the phase shift pattern is disposed to allow light passing through the phase shift pattern to undergo phase shift, and positions corresponding to the phase shift pattern are substantially opaque to light. Lateral light leakage is reduced by the phase shift pattern, and transmission rate of products become uniform, and therefore stability of products are increased.